SIX6 (Tupaia belangeri)
Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox) IPR001356 ENSTBEG00000017196 T216211_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
SIX6
M00326_2.00 		Homo sapiens
NNDATMB
VKATHNN		 PBM
Barrera et al.(2016)
SIX6_REF 		0.867 1.000
Six6
M00169_2.00 		Mus musculus
NNAYMNN
NNKRTNN		 PBM
Badis et al.(2009)
Six6_2267 		0.867 1.000
Six6
M00412_2.00 		Mus musculus
NNNTGATAYCN
NGRTATCANNN		 PBM
Berger et al.(2008)
Six6_2267 		0.867 1.000
SIX6
M05357_2.00 		Homo sapiens
NNYGATASVB
VBSTATCRNN		 SELEX
Yin et al.(2017)
SIX6_eDBD_HT-SELEX 		0.867 1.000
SIX6
M05358_2.00 		Homo sapiens
VBVYAYCRNN
NNYGRTRBVB		 SELEX
Yin et al.(2017)
SIX6_eDBD_Methyl-HT-SELEX 		0.867 1.000
Six3
M00483_2.00 		Mus musculus
NNNAYMN
NKRTNNN		 PBM
Berger et al.(2008)
Six3_1732 		0.865 0.982
SIX3
M05159_2.00 		Homo sapiens
NNYGATABBN
NVVTATCRNN		 SELEX
Yin et al.(2017)
SIX3_eDBD_HT-SELEX 		0.865 0.982
SIX3
M10698_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SIX3_Q6 		0.865 0.982
SIX6
M00325_2.00 		Homo sapiens
NNNDATMB
VKATHNNN		 PBM
Barrera et al.(2016)
SIX6_H141N 		0.865 0.982
SIX3
M05160_2.00 		Homo sapiens
NNYGATABVB
VBVTATCRNN		 SELEX
Yin et al.(2017)
SIX3_eDBD_Methyl-HT-SELEX 		0.865 0.982
six3
M02102_2.00 		Oryzias latipes
NNDAYMBNNN
NNNVKRTHNN		 PBM
Weirauch et al.(2014)
pTH5928 		0.865 0.947
Optix
M02124_2.00 		Drosophila melanogaster
NNNNNDATMN
NKATHNNNNN		 PBM
Weirauch et al.(2014)
pTH5437 		0.865 0.930
Optix
M03850_2.00 		Drosophila melanogaster
TAATYTAATTA
TAATTARATTA		 SELEX
Nitta et al.(2015)
Optix_1 		0.865 0.930
Optix
M06526_2.00 		Drosophila melanogaster
TGATA
TATCA		 B1H
Mathelier et al.(2014)
MA0199.1 		0.865 0.930
Optix
M06327_2.00 		Drosophila melanogaster
HHVTGATA
TATCABDD		 B1H
Zhu et al.(2011)
Optix_Cell_FBgn0025360 		0.865 0.930
Optix
M06328_2.00 		Drosophila melanogaster
NNNTGATA
TATCANNN		 B1H
Zhu et al.(2011)
Optix_SOLEXA_FBgn0025360 		0.865 0.930
SIX6
M00327_2.00 		Homo sapiens
NHDAYMBNN
NNVKRTHDN		 PBM
Barrera et al.(2016)
SIX6_T165A 		0.860 0.982
For this family, TFs with SR scores > 0.599 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSTBEP00000014940 Homeodomain 187 243

Links

Other Homeodomain family TFs
Other Tupaia belangeri TFs

296 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
HBP1 Homo sapiens ENSG00000105856 D 0.000
BBX Homo sapiens ENSG00000114439 D 0.000
Hbp1 Mus musculus ENSMUSG00000002996 D 0.000
CpipJ_CPIJ012042 Culex pipiens CpipJ_CPIJ012042 I 0.000
CpipJ_CPIJ014424 Culex pipiens CpipJ_CPIJ014424 I 0.000
CpipJ_CPIJ017659 Culex pipiens CpipJ_CPIJ017659 I 0.000
WUBG_09252 Wuchereria bancrofti WUBG_09252 I 0.000
AAEL000792 Aedes aegypti AAEL000792 I 0.000
ACEP10855 Atta cephalotes ACEP10855 I 0.000
ACEP10859 Atta cephalotes ACEP10859 I 0.000
ACEP25857 Atta cephalotes ACEP25857 I 0.000
ACYPI22575 Acyrthosiphon pisum ACYPI22575 I 0.000
AGAP012033 Anopheles gambiae AGAP012033 I 0.000
BGIBMGA003080 Bombyx mori BGIBMGA003080 I 0.000
BGIBMGA004367 Bombyx mori BGIBMGA004367 I 0.000
CPIJ012042 Culex quinquefasciatus CPIJ012042 I 0.000
CPIJ014424 Culex quinquefasciatus CPIJ014424 I 0.000
CPIJ017659 Culex quinquefasciatus CPIJ017659 I 0.000
SOX1 Anolis carolinensis ENSACAG00000006346 I 0.000
ENSAMXG00000007582 Astyanax mexicanus ENSAMXG00000007582 I 0.000
SOX6 Choloepus hoffmanni ENSCHOG00000005751 I 0.000
ENSCPOG00000024750 Cavia porcellus ENSCPOG00000024750 I 0.000
ENSCSAVG00000009278 Ciona savignyi ENSCSAVG00000009278 I 0.000
sox9b Danio rerio ENSDARG00000043923 I 0.000
SOX9 Dasypus novemcinctus ENSDNOG00000033826 I 0.000
ENSDORG00000003967 Dipodomys ordii ENSDORG00000003967 I 0.000
Hbp1 Dipodomys ordii ENSDORG00000010576 I 0.000
ENSDORG00000012440 Dipodomys ordii ENSDORG00000012440 I 0.000
SOX6 Erinaceus europaeus ENSEEUG00000006749 I 0.000
SOX10 Erinaceus europaeus ENSEEUG00000011263 I 0.000
SOX6 Echinops telfairi ENSETEG00000001898 I 0.000
HBP1 Echinops telfairi ENSETEG00000018542 I 0.000
ENSFALG00000002572 Ficedula albicollis ENSFALG00000002572 I 0.000
SOX13 Felis catus ENSFCAG00000002900 I 0.000
ENSMEUG00000008151 Macropus eugenii ENSMEUG00000008151 I 0.000
ENSMEUG00000011116 Macropus eugenii ENSMEUG00000011116 I 0.000
ENSMEUG00000015665 Macropus eugenii ENSMEUG00000015665 I 0.000
SOX10 Meleagris gallopavo ENSMGAG00000012508 I 0.000
SOX13 Microcebus murinus ENSMICG00000009236 I 0.000
ENSNLEG00000009528 Nomascus leucogenys ENSNLEG00000009528 I 0.000
ENSOARG00000009998 Ovis aries ENSOARG00000009998 I 0.000
SOX10 Ochotona princeps ENSOPRG00000013575 I 0.000
SOX17 Procavia capensis ENSPCAG00000003188 I 0.000
SOX10 Procavia capensis ENSPCAG00000005913 I 0.000
ENSPMAG00000010371 Petromyzon marinus ENSPMAG00000010371 I 0.000
ENSPSIG00000009504 Pelodiscus sinensis ENSPSIG00000009504 I 0.000
ENSPTRG00000005969 Pan troglodytes ENSPTRG00000005969 I 0.000
SOX3 Pteropus vampyrus ENSPVAG00000003166 I 0.000
SOX9 Pteropus vampyrus ENSPVAG00000010505 I 0.000
HBP1 Sorex araneus ENSSARG00000007731 I 0.000
SOX5 Sorex araneus ENSSARG00000007963 I 0.000
SOX12 Sus scrofa ENSSSCG00000021920 I 0.000
SOX6 Tupaia belangeri ENSTBEG00000002476 I 0.000
ENSTGUG00000002931 Taeniopygia guttata ENSTGUG00000002931 I 0.000
ENSTSYG00000012536 Tarsius syrichta ENSTSYG00000012536 I 0.000
ENSTTRG00000005878 Tursiops truncatus ENSTTRG00000005878 I 0.000
ENSVPAG00000000908 Vicugna pacos ENSVPAG00000000908 I 0.000
GB40960 Apis mellifera GB40960 I 0.000
HMEL016850 Heliconius melpomene HMEL016850 I 0.000
ISCW009925 Ixodes scapularis ISCW009925 I 0.000
L798_02392 Zootermopsis nevadensis L798_02392 I 0.000
L798_12045 Zootermopsis nevadensis L798_12045 I 0.000
LotgiG88815 Lottia gigantea LotgiG88815 I 0.000
MCINX002905 Melitaea cinxia MCINX002905 I 0.000
MESCA000459 Megaselia scalaris MESCA000459 I 0.000
MESCA009852 Megaselia scalaris MESCA009852 I 0.000
XM_002306945.1 Populus trichocarpa POPTR_0005s27390 I 0.000
Ppa-sem-2 Pristionchus pacificus PPA04955 I 0.000
RPRC012780 Rhodnius prolixus RPRC012780 I 0.000
RPRC014334 Rhodnius prolixus RPRC014334 I 0.000
SINV16626 Solenopsis invicta SINV16626 I 0.000
SINV19744 Solenopsis invicta SINV19744 I 0.000
SINV19753 Solenopsis invicta SINV19753 I 0.000
TC003791 Tribolium castaneum TC003791 I 0.000
TC009854 Tribolium castaneum TC009854 I 0.000
YQE_08560 Dendroctonus ponderosae YQE_08560 I 0.000
YQE_13042 Dendroctonus ponderosae YQE_13042 I 0.000
Gfo_R009506 Geospiza fortis Gfo_R009506 I 0.000
Hsal_04828--XP_001122993.1_APIME Harpegnathos saltator Hsal_04828--XP_001122993.1_APIME I 0.000
orange1.1g029982m.g Citrus sinensis orange1.1g029982m.g I 0.000
CLEC006959 Cimex lectularius CLEC006959 I 0.000
CLEC006961 Cimex lectularius CLEC006961 I 0.000
LCUP001585 Lucilia cuprina LCUP001585 I 0.000
XP_002935939 Xenopus tropicalis XP_002935939 I 0.000
AALB009865 Anopheles albimanus AALB009865 I 0.000
AALB009868 Anopheles albimanus AALB009868 I 0.000
AARA000827 Anopheles arabiensis AARA000827 I 0.000
AARA005391 Anopheles arabiensis AARA005391 I 0.000
AARA005393 Anopheles arabiensis AARA005393 I 0.000
AARA011914 Anopheles arabiensis AARA011914 I 0.000
ACHR009359 Anopheles christyi ACHR009359 I 0.000
ACOM022800 Anopheles coluzzii ACOM022800 I 0.000
ACOM034662 Anopheles coluzzii ACOM034662 I 0.000
ACUA008554 Anopheles culicifacies ACUA008554 I 0.000
ACUA026266 Anopheles culicifacies ACUA026266 I 0.000
ACUA026638 Anopheles culicifacies ACUA026638 I 0.000
ADIR005630 Anopheles dirus ADIR005630 I 0.000
ADIR005633 Anopheles dirus ADIR005633 I 0.000
ADIR009659 Anopheles dirus ADIR009659 I 0.000
AEPI003628 Anopheles epiroticus AEPI003628 I 0.000
AEPI010515 Anopheles epiroticus AEPI010515 I 0.000
AFAF017335 Anopheles farauti AFAF017335 I 0.000
AFUN009319 Anopheles funestus AFUN009319 I 0.000
AFUN010196 Anopheles funestus AFUN010196 I 0.000
AFUN010199 Anopheles funestus AFUN010199 I 0.000
AMAM006332 Anopheles maculatus AMAM006332 I 0.000
AMAM015893 Anopheles maculatus AMAM015893 I 0.000
AMAM018985 Anopheles maculatus AMAM018985 I 0.000
AMEC008804 Anopheles melas AMEC008804 I 0.000
AMEC012053 Anopheles melas AMEC012053 I 0.000
AMEC014560 Anopheles melas AMEC014560 I 0.000
AMEC016085 Anopheles melas AMEC016085 I 0.000
AMEM014190 Anopheles merus AMEM014190 I 0.000
AMIN001219 Anopheles minimus AMIN001219 I 0.000
AMIN008219 Anopheles minimus AMIN008219 I 0.000
AMIN009301 Anopheles minimus AMIN009301 I 0.000
AMIN009304 Anopheles minimus AMIN009304 I 0.000
AQUA001262 Anopheles quadriannulatus AQUA001262 I 0.000
AQUA004309 Anopheles quadriannulatus AQUA004309 I 0.000
ASTEI06407 Anopheles stephensi ASTEI06407 I 0.000
BGLB002734 Biomphalaria glabrata BGLB002734 I 0.000
BGLB010904 Biomphalaria glabrata BGLB010904 I 0.000
LLOJ005525 Lutzomyia longipalpis LLOJ005525 I 0.000
ANCCEY_13259 Ancylostoma ceylanicum ANCCEY_13259 I 0.000
ANCCEY_13724 Ancylostoma ceylanicum ANCCEY_13724 I 0.000
ANCDUO_17471 Ancylostoma duodenale ANCDUO_17471 I 0.000
ASIM_0001251801 Anisakis simplex ASIM_0001251801 I 0.000
ASU_00571 Ascaris suum ASU_00571 I 0.000
CGOC_0001130501 Cylicostephanus goldi CGOC_0001130501 I 0.000
DICVIV_00403 Dictyocaulus viviparus DICVIV_00403 I 0.000
genemark-nMf.1.1.scaf16788-processed-gene-0.1 Meloidogyne floridensis genemark-nMf.1.1.scaf16788-processed-gene-0.1 I 0.000
Hba_12930 Heterorhabditis bacteriophora Hba_12930 I 0.000
HCOI00604400 Haemonchus contortus HCOI00604400 I 0.000
HPLM_0001473301 Haemonchus placei HPLM_0001473301 I 0.000
L898_g3197 Steinernema monticolum L898_g3197 I 0.000
NBR_0000360901 Nippostrongylus brasiliensis NBR_0000360901 I 0.000
NBR_0002216901 Nippostrongylus brasiliensis NBR_0002216901 I 0.000
nDi.2.2.2.g10379 Dirofilaria immitis nDi.2.2.2.g10379 I 0.000
NECAME_01431 Necator americanus NECAME_01431 I 0.000
nLs.2.1.2.g10155 Litomosoides sigmodontis nLs.2.1.2.g10155 I 0.000
OESDEN_03870 Oesophagostomum dentatum OESDEN_03870 I 0.000
PEQ_0000771101 Parascaris equorum PEQ_0000771101 I 0.000
PTRK_0001690900 Parastrongyloides trichosuri PTRK_0001690900 I 0.000
RSKR_0000175300 Rhabditophanes kr3021 RSKR_0000175300 I 0.000
RSKR_0000922300 Rhabditophanes kr3021 RSKR_0000922300 I 0.000
scaffold2272-EXSNAP2012.1 Pristionchus exspectatus scaffold2272-EXSNAP2012.1 I 0.000
SMUV_0000965701 Syphacia muris SMUV_0000965701 I 0.000
SPAL_0000118400 Strongyloides papillosus SPAL_0000118400 I 0.000
SSTP_0000971600 Strongyloides stercoralis SSTP_0000971600 I 0.000
SVE_0463600 Strongyloides venezuelensis SVE_0463600 I 0.000
TCLT_0000083701 Thelazia callipaeda TCLT_0000083701 I 0.000
TCNE_0001308501 Toxocara canis TCNE_0001308501 I 0.000
TELCIR_02961 Teladorsagia circumcincta TELCIR_02961 I 0.000
CpipJ_CPIJ012500 Culex pipiens CpipJ_CPIJ012500 N 0.000
CpipJ_CPIJ014016 Culex pipiens CpipJ_CPIJ014016 N 0.000
ACEP25270 Atta cephalotes ACEP25270 N 0.000
CPIJ012500 Culex quinquefasciatus CPIJ012500 N 0.000
CPIJ014016 Culex quinquefasciatus CPIJ014016 N 0.000
DAPPUDRAFT_346928 Daphnia pulex DAPPUDRAFT_346928 N 0.000
ENSGMOG00000014613 Gadus morhua ENSGMOG00000014613 N 0.000
SOX11 Ornithorhynchus anatinus ENSOANG00000006361 N 0.000
SOX6 Procavia capensis ENSPCAG00000001398 N 0.000
GH23191 Drosophila grimshawi FBgn0130648 N 0.000
GLOINDRAFT_28614 Rhizophagus irregularis GLOINDRAFT_28614 N 0.000
GLYMA01G28253 Glycine max GLYMA01G28253 N 0.000
GRMZM2G144398 Zea mays GRMZM2G144398 N 0.000
HelroG148277 Helobdella robusta HelroG148277 N 0.000
KGM_05609 Danaus plexippus KGM_05609 N 0.000
L798_04020 Zootermopsis nevadensis L798_04020 N 0.000
L798_09360 Zootermopsis nevadensis L798_09360 N 0.000
ML23337a Mnemiopsis leidyi ML23337a N 0.000
PHUM433270 Pediculus humanus PHUM433270 N 0.000
RPRC012125 Rhodnius prolixus RPRC012125 N 0.000
SEPMUDRAFT_152382 Sphaerulina musiva SEPMUDRAFT_152382 N 0.000
SMAR010127 Strigamia maritima SMAR010127 N 0.000
Cflo_01077--XP_001122045.1_APIME Camponotus floridanus Cflo_01077--XP_001122045.1_APIME N 0.000
Hsal_04214--XP_001122045.1_APIME Harpegnathos saltator Hsal_04214--XP_001122045.1_APIME N 0.000
Ogr19131 Ophisaurus gracilis Ogr19131 N 0.000
Ocbimv22020621m.g Octopus bimaculoides Ocbimv22020621m.g N 0.000
LDEC007549 Leptinotarsa decemlineata LDEC007549 N 0.000
Sjc_0095610 Schistosoma japonicum Sjc_0095610 N 0.000
AATE006542 Anopheles atroparvus AATE006542 N 0.000
AATE012157 Anopheles atroparvus AATE012157 N 0.000
ACOM026664 Anopheles coluzzii ACOM026664 N 0.000
ACUA011783 Anopheles culicifacies ACUA011783 N 0.000
AEPI007651 Anopheles epiroticus AEPI007651 N 0.000
AEPI007946 Anopheles epiroticus AEPI007946 N 0.000
AMAM022760 Anopheles maculatus AMAM022760 N 0.000
ASIS016076 Anopheles sinensis ASIS016076 N 0.000
ASTEI06129 Anopheles stephensi ASTEI06129 N 0.000
PPAI008595 Phlebotomus papatasi PPAI008595 N 0.000
PPAI009257 Phlebotomus papatasi PPAI009257 N 0.000
ACAC_0000143401 Angiostrongylus cantonensis ACAC_0000143401 N 0.000
ANCCAN_22368 Ancylostoma caninum ANCCAN_22368 N 0.000
augustus_masked-nMf.1.1.scaf12176-processed-gene-0.0 Meloidogyne floridensis augustus_masked-nMf.1.1.scaf12176-processed-gene-0.0 N 0.000
D918_08316 Trichuris suis D918_08316 N 0.000
PXEA_0001829801 Protopolystoma xenopodis PXEA_0001829801 N 0.000
RSKR_0000394100 Rhabditophanes kr3021 RSKR_0000394100 N 0.000
SPER_0000213401 Spirometra erinaceieuropaei SPER_0000213401 N 0.000