six2 (Xenopus tropicalis)
Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00046 (Homeobox) IPR001356 XB-GENE-481504 T230449_2.00 Misc (2018-Jan-19)

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Six2
M00425_2.00 		Mus musculus
NNAYMYNN
NNRKRTNN		 PBM
Berger et al.(2008)
Six2_2307 		0.867 1.000
SIX2
M05285_2.00 		Homo sapiens
NNYGATACSB
VSGTATCRNN		 SELEX
Yin et al.(2017)
SIX2_eDBD_HT-SELEX 		0.867 1.000
SIX2
M05287_2.00 		Homo sapiens
NSGTRWCRYN
NRYGWYACSN		 SELEX
Yin et al.(2017)
SIX2_FL_HT-SELEX 		0.867 1.000
SIX2
M08133_2.00 		Homo sapiens
NNNTGWAACCTGAKMH
DKMTCAGGTTWCANNN		 ChIP-seq
Mathelier et al.(2014)
MA1119.1 		0.867 1.000
SIX2
M09157_2.00 		Homo sapiens
DGWAAYHHGABMH
DKVTCDDRTTWCH		 Misc
Kulakovskiy et al.(2013)
SIX2_HUMAN.H11MO.0.A 		0.867 1.000
Six2
M09185_2.00 		Mus musculus
DGWAAYHYRABMYB
VRKVTYRDRTTWCH		 Misc
Kulakovskiy et al.(2013)
SIX2_MOUSE.H11MO.0.A 		0.867 1.000
SIX2
M05286_2.00 		Homo sapiens
NBRTATCRNN
NNYGATAYVN		 SELEX
Yin et al.(2017)
SIX2_eDBD_Methyl-HT-SELEX 		0.867 1.000
SIX2
M05288_2.00 		Homo sapiens
VBRTAWCRNN
NNYGWTAYVB		 SELEX
Yin et al.(2017)
SIX2_FL_Methyl-HT-SELEX 		0.867 1.000
so
M02117_2.00 		Drosophila melanogaster
NDATMYNNN
NNNRKATHN		 PBM
Weirauch et al.(2014)
pTH5690 		0.866 0.945
so
M03800_2.00 		Drosophila melanogaster
NYGATAYB
VRTATCRN		 SELEX
Nitta et al.(2015)
so_1 		0.866 0.945
so
M03801_2.00 		Drosophila melanogaster
YKATAYNNNYGATAY
RTATCRNNNRTATMR		 SELEX
Nitta et al.(2015)
so_2 		0.866 0.945
so
M03802_2.00 		Drosophila melanogaster
YGATACGTATCR
YGATACGTATCR		 SELEX
Nitta et al.(2015)
so_3 		0.866 0.945
so
M03803_2.00 		Drosophila melanogaster
RTATCRYGATAC
GTATCRYGATAY		 SELEX
Nitta et al.(2015)
so_4 		0.866 0.945
so
M06497_2.00 		Drosophila melanogaster
TGATAC
GTATCA		 B1H
Mathelier et al.(2014)
MA0246.1 		0.866 0.945
so
M06268_2.00 		Drosophila melanogaster
NRTGATA
TATCAYN		 B1H
Zhu et al.(2011)
So_Cell_FBgn0003460 		0.866 0.945
so
M06269_2.00 		Drosophila melanogaster
NNNTGATA
TATCANNN		 B1H
Zhu et al.(2011)
So_SOLEXA_FBgn0003460 		0.866 0.945
Six1
M00512_2.00 		Mus musculus
NNDATMYNNN
NNNRKATHNN		 PBM
Berger et al.(2008)
Six1_0935 		0.865 0.982
SIX1
M05094_2.00 		Homo sapiens
NNYGATACVB
VBGTATCRNN		 SELEX
Yin et al.(2017)
SIX1_eDBD_HT-SELEX 		0.865 0.982
SIX1
M05096_2.00 		Homo sapiens
NNYGATAYVB
VBRTATCRNN		 SELEX
Yin et al.(2017)
SIX1_FL_HT-SELEX 		0.865 0.982
SIX1
M08130_2.00 		Homo sapiens
GWAACCTGANM
KNTCAGGTTWC		 ChIP-seq
Mathelier et al.(2014)
MA1118.1 		0.865 0.982
SIX1
M09142_2.00 		Homo sapiens
DGWAAYHTGABMYN
NRKVTCADRTTWCH		 Misc
Kulakovskiy et al.(2013)
SIX1_HUMAN.H11MO.0.A 		0.865 0.982
Six1
M09579_2.00 		Mus musculus
GWAAYHTGABMH
DKVTCADRTTWC		 Misc
Heinz et al.(2010)
Myoblast-Six1_GSE20150 		0.865 0.982
SIX1
M10684_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SIX1_Q3_01 		0.865 0.982
SIX1
M10685_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SIX1_Q3 		0.865 0.982
SIX1
M05095_2.00 		Homo sapiens
NNYGATABNB
VNVTATCRNN		 SELEX
Yin et al.(2017)
SIX1_eDBD_Methyl-HT-SELEX 		0.865 0.982
SIX1
M05097_2.00 		Homo sapiens
NNYGATAYSB
VSRTATCRNN		 SELEX
Yin et al.(2017)
SIX1_FL_Methyl-HT-SELEX 		0.865 0.982
Six4
M00461_2.00 		Mus musculus
NNKABMHNN
NNDKVTMNN		 PBM
Berger et al.(2008)
Six4_2860 		0.708 0.709
SIX4
M04939_2.00 		Homo sapiens
NVYGATACVB
VBGTATCRBN		 SELEX
Yin et al.(2017)
SIX4_eDBD_HT-SELEX 		0.708 0.709
Six4
M09198_2.00 		Mus musculus
DGDAABHNSASNNN
NNNSTSNDVTTHCH		 Misc
Kulakovskiy et al.(2013)
SIX4_MOUSE.H11MO.0.C 		0.708 0.709
SIX4
M10646_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SIX4_Q3 		0.708 0.709
SIX4
M04940_2.00 		Homo sapiens
NBGTAWCRHN
NDYGWTACVN		 SELEX
Yin et al.(2017)
SIX4_eDBD_Methyl-HT-SELEX 		0.708 0.709
Six4
M00563_2.00 		Drosophila melanogaster
NNDANMHNN
NNDKNTHNN		 PBM
Busser et al.(2012a)
Six4 		0.708 0.673
Six4
M06530_2.00 		Drosophila melanogaster
TGABAC
GTVTCA		 B1H
Mathelier et al.(2014)
MA0204.1 		0.708 0.673
Six4
M06334_2.00 		Drosophila melanogaster
WDDTGABAC
GTVTCAHHW		 B1H
Zhu et al.(2011)
Six4_Cell_FBgn0027364 		0.708 0.673
Six4
M06335_2.00 		Drosophila melanogaster
NTGAKACB
VGTMTCAN		 B1H
Zhu et al.(2011)
Six4_SOLEXA_2_FBgn0027364 		0.708 0.673
Six4
M06336_2.00 		Drosophila melanogaster
NNNTGABA
TVTCANNN		 B1H
Zhu et al.(2011)
Six4_SOLEXA_FBgn0027364 		0.708 0.673
SIX5
M08208_2.00 		Homo sapiens
GARWTGTAGT
ACTACAWYTC		 ChIP-seq
Contrino et al.(2012)
Mv121 		0.708 0.655
SIX5
M08209_2.00 		Homo sapiens
GGAGTTGT
ACAACTCC		 ChIP-seq
Contrino et al.(2012)
Mv123 		0.708 0.655
SIX5
M10738_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SIX5_01 		0.708 0.655
SIX5
M10739_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SIX5_02 		0.708 0.655
ceh-34
M00672_2.00 		Caenorhabditis elegans
NNNRDAWNNN
NNNWTHYNNN		 PBM
Narasimhan et al.(2015)
pTH9708 		0.664 0.618
For this family, TFs with SR scores > 0.599 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
AAI35533 Homeodomain 127 181

Links

Other Homeodomain family TFs
Other Xenopus tropicalis TFs

540 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
Traes_3AS_037375C84 Triticum aestivum Traes_3AS_037375C84 N 0.000
ORGLA01G0397100 Oryza glaberrima ORGLA01G0397100 N 0.000
ORGLA08G0199700 Oryza glaberrima ORGLA08G0199700 N 0.000
ORUFI01G06710 Oryza rufipogon ORUFI01G06710 N 0.000
OS01G0195801 Oryza sativa OS01G0195801 N 0.000
OS01G0196300 Oryza sativa OS01G0196300 N 0.000
Sb03g002910 Sorghum bicolor Sb03g002910 N 0.000
Sb09g006220 Sorghum bicolor Sb09g006220 N 0.000
Si001328m.g Setaria italica Si001328m.g N 0.000
ORGLA01G0058200 Oryza glaberrima ORGLA01G0058200 N 0.000
Traes_3B_99CDB9674 Triticum aestivum Traes_3B_99CDB9674 N 0.000
TRAES3BF075700010CFD_g Triticum aestivum TRAES3BF075700010CFD_g N 0.000
TRAES3BF076600020CFD_g Triticum aestivum TRAES3BF076600020CFD_g N 0.000
TRIUR3_35423 Triticum urartu TRIUR3_35423 N 0.000
Cla011379 Citrullus lanatus Cla011379 N 0.000
Cucsa.155340 Cucumis sativus Cucsa.155340 N 0.000
Pavir.Ba03537 Panicum virgatum Pavir.Ba03537 N 0.000
Pavir.Ea00369 Panicum virgatum Pavir.Ea00369 N 0.000
OBART01G06120 Oryza barthii OBART01G06120 N 0.000
BGIOSGA002943 Oryza indica BGIOSGA002943 N 0.000
BRADI2G05950 Brachypodium distachyon BRADI2G05950 N 0.000
GRMZM2G132550 Zea mays GRMZM2G132550 N 0.000
GRMZM2G333582 Zea mays GRMZM2G333582 N 0.000
GRMZM2G397755 Zea mays GRMZM2G397755 N 0.000
LPERR01G05820 Leersia perrieri LPERR01G05820 N 0.000
MLOC_21524 Hordeum vulgare MLOC_21524 N 0.000
OB01G16120 Oryza brachyantha OB01G16120 N 0.000
BGIOSGA002940 Oryza indica BGIOSGA002940 N 0.000
OBART01G06170 Oryza barthii OBART01G06170 N 0.000
OGLUM01G06690 Oryza glumaepatula OGLUM01G06690 N 0.000
OGLUM01G06730 Oryza glumaepatula OGLUM01G06730 N 0.000
OMERI01G06310 Oryza meridionalis OMERI01G06310 N 0.000
ONIVA01G07080 Oryza nivara ONIVA01G07080 N 0.000
ONIVA01G07190 Oryza nivara ONIVA01G07190 N 0.000
OPUNC01G05940 Oryza punctata OPUNC01G05940 N 0.000