nkx6.1 (Tetraodon nigroviridis)
Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox) IPR001356 ENSTNIG00000009010 T216468_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Nkx6-1
M00466_2.00 		Mus musculus
NDTDATNRN
NYNATHAHN		 PBM
Berger et al.(2008)
Nkx6-1_2825 		0.867 1.000
NKX6-1
M09151_2.00 		Homo sapiens
RAHWRATKDSNWWWTRATD
HATYAWWWNSHMATYWDTY		 Misc
Kulakovskiy et al.(2013)
NKX61_HUMAN.H11MO.0.B 		0.867 1.000
Nkx6-1
M09200_2.00 		Mus musculus
HNWRATKDNHWWWTRATDR
YHATYAWWWDNHMATYWND		 Misc
Kulakovskiy et al.(2013)
NKX61_MOUSE.H11MO.0.A 		0.867 1.000
Nkx6-1
M09573_2.00 		Mus musculus
NDTAATKR
YMATTAHN		 Misc
Heinz et al.(2010)
Islet-Nkx6.1_GSE40975 		0.867 1.000
NKX6-1
M10718_2.00 		Homo sapiens
HWTTTAATKGRWT
AWYCMATTAAAWD		 Transfac
Matys et al.(2006)
V$NKX61_01 		0.867 1.000
NKX6-1
M10719_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NKX61_08 		0.867 1.000
Nkx6-3
M00522_2.00 		Mus musculus
NDYDATNRN
NYNATHRHN		 PBM
Berger et al.(2008)
Nkx6-3_3446 		0.867 0.965
NKX6-3
M05242_2.00 		Homo sapiens
NWTAATGRB
VYCATTAWN		 SELEX
Yin et al.(2017)
NKX6-3_eDBD_HT-SELEX 		0.867 0.965
NKX6-3
M05243_2.00 		Homo sapiens
DWTAATGRB
VYCATTAWH		 SELEX
Yin et al.(2017)
NKX6-3_eDBD_Methyl-HT-SELEX 		0.867 0.965
NKX6-2
M05184_2.00 		Homo sapiens
DTAATTRN
NYAATTAH		 SELEX
Yin et al.(2017)
NKX6-2_eDBD_HT-SELEX 		0.858 0.982
NKX6-2
M05186_2.00 		Homo sapiens
WTAATKAB
VTMATTAW		 SELEX
Yin et al.(2017)
NKX6-2_FL_HT-SELEX 		0.858 0.982
NKX6-2
M10711_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NKX62_Q2 		0.858 0.982
NKX6-2
M05185_2.00 		Homo sapiens
NTMATKRN
NYMATKAN		 SELEX
Yin et al.(2017)
NKX6-2_eDBD_Methyl-HT-SELEX 		0.858 0.982
NKX6-2
M05187_2.00 		Homo sapiens
WTAATKAB
VTMATTAW		 SELEX
Yin et al.(2017)
NKX6-2_FL_Methyl-HT-SELEX 		0.858 0.982
HGTX
M03869_2.00 		Drosophila melanogaster
DTAATKRN
NYMATTAH		 SELEX
Nitta et al.(2015)
HGTX_1 		0.855 0.947
HGTX
M03870_2.00 		Drosophila melanogaster
DTAATKRN
NYMATTAH		 SELEX
Nitta et al.(2015)
HGTX_2 		0.855 0.947
HGTX
M06542_2.00 		Drosophila melanogaster
DTAATKA
TMATTAH		 B1H
Mathelier et al.(2014)
MA0191.1 		0.855 0.947
HGTX
M06360_2.00 		Drosophila melanogaster
DDTAATKA
TMATTAHH		 B1H
Zhu et al.(2011)
Hgtx_Cell_FBgn0040318 		0.855 0.947
HGTX
M06361_2.00 		Drosophila melanogaster
NWTAATKA
TMATTAWN		 B1H
Zhu et al.(2011)
Hgtx_SOLEXA_FBgn0040318 		0.855 0.947
CBG20882
M01244_2.00 		Caenorhabditis briggsae
NDHDATDRN
NYHATHDHN		 PBM
Lambert et al.(2019)
pTH11477 		0.811 0.737
Q0N4H9_NEMVE
M02165_2.00 		Nematostella vectensis
NNYRWWNNN
NNNWWYRNN		 PBM
Weirauch et al.(2014)
pTH6101 		0.685 0.579
NEMVEDRAFT_v1g129868
M02146_2.00 		Nematostella vectensis
NYRAWNDNN
NNHNWTYRN		 PBM
Weirauch et al.(2014)
pTH5749 		0.679 0.579
NK7.1
M03847_2.00 		Drosophila melanogaster
VTTAAAYGDTD
HAHCRTTTAAB		 SELEX
Nitta et al.(2015)
NK7.1_1 		0.617 0.614
NK7.1
M03848_2.00 		Drosophila melanogaster
NSTTAATTGVY
RBCAATTAASN		 SELEX
Nitta et al.(2015)
NK7.1_2 		0.617 0.614
NK7.1
M06524_2.00 		Drosophila melanogaster
TTAATDR
YHATTAA		 B1H
Mathelier et al.(2014)
MA0196.1 		0.617 0.614
NK7.1
M06323_2.00 		Drosophila melanogaster
NTTAATDR
YHATTAAN		 B1H
Zhu et al.(2011)
NK7.1_Cell_FBgn0024321 		0.617 0.614
NK7.1
M06324_2.00 		Drosophila melanogaster
YTAATDR
YHATTAR		 B1H
Zhu et al.(2011)
NK7.1_SOLEXA_FBgn0024321 		0.617 0.614
For this family, TFs with SR scores > 0.599 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSTNIP00000011865 Homeodomain 178 234

Links

Other Homeodomain family TFs
Other Tetraodon nigroviridis TFs

311 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
AAEL013896 Aedes aegypti AAEL013896 I
AAH84196 Xenopus laevis AAH84196 I
AALB009485 Anopheles albimanus AALB009485 I
Aan_R014474 Calypte anna Aan_R014474 I
AARA004719 Anopheles arabiensis AARA004719 I
AATE010695 Anopheles atroparvus AATE010695 I
ACHR000067 Anopheles christyi ACHR000067 I
ACOM037505 Anopheles coluzzii ACOM037505 I
ACUA025512 Anopheles culicifacies ACUA025512 I
ACYPI000365 Acyrthosiphon pisum ACYPI000365 I
ACYPI003759 Acyrthosiphon pisum ACYPI003759 I
ACYPI005550 Acyrthosiphon pisum ACYPI005550 I
ACYPI008450 Acyrthosiphon pisum ACYPI008450 I
ADAC007516 Anopheles darlingi ADAC007516 I
ADIR002761 Anopheles dirus ADIR002761 I
AEPI002385 Anopheles epiroticus AEPI002385 I
AFAF011208 Anopheles farauti AFAF011208 I
Afo_R008709 Aptenodytes forsteri Afo_R008709 I
AFUN009864 Anopheles funestus AFUN009864 I
AGAP002902 Anopheles gambiae AGAP002902 I
Alligator_sinensis_CCG001823.1 Alligator sinensis Alligator_sinensis_CCG001823.1 I
Alligator_sinensis_CCG008910.1 Alligator sinensis Alligator_sinensis_CCG008910.1 I
AMAM019778 Anopheles maculatus AMAM019778 I
AMEM015931 Anopheles merus AMEM015931 I
AMIN000723 Anopheles minimus AMIN000723 I
Aqu1.215833 Amphimedon queenslandica Aqu1.215833 I
Aqu1.215834 Amphimedon queenslandica Aqu1.215834 I
AQUA009305 Anopheles quadriannulatus AQUA009305 I
ASTEI00079 Anopheles stephensi ASTEI00079 I
BGIBMGA010110 Bombyx mori BGIBMGA010110 I
BGLB014287 Biomphalaria glabrata BGLB014287 I
Brh_R010414 Buceros rhinoceros Brh_R010414 I
CapteG179368 Capitella teleta CapteG179368 I
Cflo_07183--XP_392838.3_APIME Camponotus floridanus Cflo_07183--XP_392838.3_APIME I
CGI_10000594 Crassostrea gigas CGI_10000594 I
CLEC002594 Cimex lectularius CLEC002594 I
Cmyd_10005540 Chelonia mydas Cmyd_10005540 I
CPIJ002563 Culex quinquefasciatus CPIJ002563 I
CpipJ_CPIJ002563 Culex pipiens CpipJ_CPIJ002563 I
DAPPUDRAFT_304115 Daphnia pulex DAPPUDRAFT_304115 I
ENSAMEG00000002899 Ailuropoda melanoleuca ENSAMEG00000002899 I
ENSAMXG00000017275 Astyanax mexicanus ENSAMXG00000017275 I
ENSAMXG00000018339 Astyanax mexicanus ENSAMXG00000018339 I
ENSAMXG00000019219 Astyanax mexicanus ENSAMXG00000019219 I
ENSAPLG00000003924 Anas platyrhynchos ENSAPLG00000003924 I
ENSCSAG00000018094 Chlorocebus sabaeus ENSCSAG00000018094 I
ENSCSAVG00000006480 Ciona savignyi ENSCSAVG00000006480 I
ENSGACG00000003171 Gasterosteus aculeatus ENSGACG00000003171 I
ENSGACG00000016858 Gasterosteus aculeatus ENSGACG00000016858 I
ENSGMOG00000000297 Gadus morhua ENSGMOG00000000297 I
ENSGMOG00000005844 Gadus morhua ENSGMOG00000005844 I
ENSGMOG00000013964 Gadus morhua ENSGMOG00000013964 I
ENSLACG00000007810 Latimeria chalumnae ENSLACG00000007810 I
ENSMEUG00000001823 Macropus eugenii ENSMEUG00000001823 I
ENSMPUG00000008776 Mustela putorius furo ENSMPUG00000008776 I
ENSNLEG00000011859 Nomascus leucogenys ENSNLEG00000011859 I
ENSOANG00000030959 Ornithorhynchus anatinus ENSOANG00000030959 I
ENSOARG00000004662 Ovis aries ENSOARG00000004662 I
ENSONIG00000001557 Oreochromis niloticus ENSONIG00000001557 I
ENSONIG00000010360 Oreochromis niloticus ENSONIG00000010360 I
ENSONIG00000014036 Oreochromis niloticus ENSONIG00000014036 I
ENSONIG00000015035 Oreochromis niloticus ENSONIG00000015035 I
ENSP00000341551-D1 Bos grunniens ENSP00000341551-D1 I
ENSP00000381452 Macaca fascicularis ENSP00000381452 I
ENSPANG00000024703 Papio anubis ENSPANG00000024703 I
ENSPFOG00000018987 Poecilia formosa ENSPFOG00000018987 I
ENSPFOG00000019807 Poecilia formosa ENSPFOG00000019807 I
ENSPFOG00000019867 Poecilia formosa ENSPFOG00000019867 I
ENSPMAG00000008404 Petromyzon marinus ENSPMAG00000008404 I
ENSPMAG00000009414 Petromyzon marinus ENSPMAG00000009414 I
ENSPPYG00000009165 Pongo abelii ENSPPYG00000009165 I
ENSPSIG00000014614 Pelodiscus sinensis ENSPSIG00000014614 I
ENSSHAG00000010344 Sarcophilus harrisii ENSSHAG00000010344 I
ENSSTOG00000028580 Ictidomys tridecemlineatus ENSSTOG00000028580 I
ENSTSYG00000009792 Tarsius syrichta ENSTSYG00000009792 I
ENSXMAG00000005051 Xiphophorus maculatus ENSXMAG00000005051 I
ENSXMAG00000015245 Xiphophorus maculatus ENSXMAG00000015245 I
e_gw.452.68.1 Branchiostoma floridae e_gw.452.68.1 I
fgenesh2_pg.scaffold_230000050 Branchiostoma floridae fgenesh2_pg.scaffold_230000050 I
GA14643 Drosophila pseudoobscura FBgn0074670 I
GB50071 Apis mellifera GB50071 I
gb:cr929477 Tetraodon nigroviridis ENSTNIG00000003193 I
gb:cr929477 Takifugu rubripes ENSTRUG00000011769 I
GE10952 Drosophila yakuba FBgn0228782 I
GF22974 Drosophila ananassae FBgn0099968 I
Gfo_R011803 Geospiza fortis Gfo_R011803 I
Gfo_R016223 Geospiza fortis Gfo_R016223 I
GG11819 Drosophila erecta FBgn0104114 I
GH18642 Drosophila grimshawi FBgn0126109 I
GI23400 Drosophila mojavensis FBgn0146126 I
GJ23092 Drosophila virilis FBgn0210194 I
GK11724 Drosophila willistoni FBgn0213735 I
GL23637 Drosophila persimilis FBgn0161227 I
GM16436 Drosophila sechellia FBgn0171351 I
HHAL000393-PA Halyomorpha halys HHAL000393-PA I
HHAL000394-PA Halyomorpha halys HHAL000394-PA I
HMEL002203 Heliconius melpomene HMEL002203 I
Hsal_09633--XP_392838.3_APIME Harpegnathos saltator Hsal_09633--XP_392838.3_APIME I
ISCW018468 Ixodes scapularis ISCW018468 I
KGM_12572 Danaus plexippus KGM_12572 I
L798_13939 Zootermopsis nevadensis L798_13939 I
LCUP007928 Lucilia cuprina LCUP007928 I
LDEC015949 Leptinotarsa decemlineata LDEC015949 I
LLOJ008806 Lutzomyia longipalpis LLOJ008806 I
LotgiG131078 Lottia gigantea LotgiG131078 I
MCINX014520 Melitaea cinxia MCINX014520 I
MDOA012885 Musca domestica MDOA012885 I
Med Drosophila melanogaster FBgn0011655 D
Myotis_brandtii_Smad4_10005924 Myotis brandtii Myotis_brandtii_Smad4_10005924 I
NEMVEDRAFT_v1g248037 Nematostella vectensis NEMVEDRAFT_v1g248037 I
NV12984 Nasonia vitripennis NV12984 I
Ocbimv22032358m.g Octopus bimaculoides Ocbimv22032358m.g I
Ogr06720 Ophisaurus gracilis Ogr06720 I
Ogr14199 Ophisaurus gracilis Ogr14199 I
PHUM002670 Pediculus humanus PHUM002670 I
PPAI002168 Phlebotomus papatasi PPAI002168 I
Pvit_01119 Pogona vitticeps Pvit_01119 I
RPRC010188 Rhodnius prolixus RPRC010188 I
si:dkey-222b8.1 Danio rerio ENSDARG00000045094 I
si:dkey-222b8.1 Gasterosteus aculeatus ENSGACG00000000538 I
si:dkey-222b8.1 Tetraodon nigroviridis ENSTNIG00000005007 I
si:dkey-222b8.1 Takifugu rubripes ENSTRUG00000004163 I
si:dkey-239n17.4 Danio rerio ENSDARG00000070428 I
SINV15516 Solenopsis invicta SINV15516 I
SMAD4 Anolis carolinensis ENSACAG00000010186 I
SMAD4 Bos taurus ENSBTAG00000006919 I
SMAD4 Canis familiaris ENSCAFG00000000164 I
SMAD4 Choloepus hoffmanni ENSCHOG00000000860 I
smad4 Ciona intestinalis ENSCING00000005559 I
SMAD4 Callithrix jacchus ENSCJAG00000001910 I
SMAD4 Cavia porcellus ENSCPOG00000006470 I
SMAD4 Danio rerio ENSDARG00000012649 I
SMAD4 Dasypus novemcinctus ENSDNOG00000005063 I
Smad4 Dipodomys ordii ENSDORG00000009089 I
SMAD4 Equus caballus ENSECAG00000017857 I
SMAD4 Echinops telfairi ENSETEG00000007750 I
SMAD4 Felis catus ENSFCAG00000005257 I
SMAD4 Homo sapiens ENSG00000141646 D
SMAD4 Gorilla gorilla ENSGGOG00000013662 I
SMAD4 Loxodonta africana ENSLAFG00000012595 I
SMAD4 Myotis lucifugus ENSMLUG00000013944 I
SMAD4 Macaca mulatta ENSMMUG00000018334 I
SMAD4 Monodelphis domestica ENSMODG00000010995 I
Smad4 Mus musculus ENSMUSG00000024515 D
SMAD4 Ornithorhynchus anatinus ENSOANG00000008117 I
SMAD4 Oryctolagus cuniculus ENSOCUG00000003929 I
SMAD4 Otolemur garnettii ENSOGAG00000012081 I
SMAD4 Ochotona princeps ENSOPRG00000013601 I
SMAD4 Oryzias latipes ENSORLG00000007703 I
SMAD4 Pan troglodytes ENSPTRG00000010028 I
Smad4 Rattus norvegicus ENSRNOG00000051965 I
SMAD4 Sus scrofa ENSSSCG00000004524 I
SMAD4 Tupaia belangeri ENSTBEG00000014105 I
SMAD4 Tetraodon nigroviridis ENSTNIG00000009050 I
SMAD4 Takifugu rubripes ENSTRUG00000014045 I
SMAD4 Vicugna pacos ENSVPAG00000006757 I
smad4.1 Xenopus tropicalis XB-GENE-485691 I
smad4.1.L Xenopus laevis XB-GENE-865543 I
smad4.2.L Xenopus laevis XB-GENE-6256010 I
smad4.2.S Xenopus laevis XB-GENE-5995204 I
smad4a Danio rerio ENSDARG00000075226 I
smad4a Gasterosteus aculeatus ENSGACG00000007495 I
smad4a Oryzias latipes ENSORLG00000005020 I
SMAR013850 Strigamia maritima SMAR013850 I
SMU15015494 Schmidtea mediterranea SMU15015494 I
SPU_004287 Strongylocentrotus purpuratus SPU_004287 I
SPU_017971 Strongylocentrotus purpuratus SPU_017971 I
TC010848 Tribolium castaneum TC010848 I
tetur10g00400 Tetranychus urticae tetur10g00400 I
YQE_06624 Dendroctonus ponderosae YQE_06624 I
YQE_08737 Dendroctonus ponderosae YQE_08737 I