CIS-BP Database: Catalog of Inferred Sequence Binding Preferences

TF Information

pax2a *(Danio rerio)* Paired box
Pfam ID	Interpro ID	Gene ID	CIS-BP ID	Sequence source	Animal TF db
PF00292 (PAX)	IPR001523	ENSDARG00000028148	T311611_2.00	Ensembl (2018-Dec-8)	Link out
Directly determined binding motifs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
No direct experiments
Motifs from related TFs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
Pax5B M01301_2.00	Gallus gallus	NSNDTNNNN	NNNNAHNSN	PBM Lambert et al.(2019) pTH9781	0.992	0.992
PAX5 M03443_2.00	Homo sapiens	RNBYANYSAWSCGTRACN	NGTYACGSWTSRNTRVNY	SELEX Jolma et al.(2013) PAX5_1	0.992	0.992
PAX5 M08160_2.00	Homo sapiens	RDGCGTGACCNN	NNGGTCACGCHY	ChIP-seq Mathelier et al.(2014) MA0014.3	0.984	0.984
PAX5 M07995_2.00	Homo sapiens	BCAVYSRDSCRKRRC	GYYMYGSHYSRBTGV	ChIP-seq Gerstein et al.(2012) GM12878_PAX5C20_HudsonAlpha	0.984	0.984
PAX5 M07996_2.00	Homo sapiens	BCASYSRDSCRTRAC	GTYAYGSHYSRSTGV	ChIP-seq Gerstein et al.(2012) GM12878_PAX5N19_HudsonAlpha	0.992	0.992
PAX5 M07997_2.00	Homo sapiens	CASYSRDSCRKRACN	NGTYMYGSHYSRSTG	ChIP-seq Gerstein et al.(2012) GM12891_PAX5C20_HudsonAlpha	0.984	0.984
PAX5 M07998_2.00	Homo sapiens	BCASYSRDSCGKRRC	GYYMCGSHYSRSTGV	ChIP-seq Gerstein et al.(2012) GM12892_PAX5C20_HudsonAlpha	0.992	0.992
PAX5 M08227_2.00	Homo sapiens	BCANYSRDGCGTRAM	KTYACGCHYSRNTGV	ChIP-seq Contrino et al.(2012) Mv108	0.992	0.992
PAX5 M08228_2.00	Homo sapiens	AGCGTGRCYG	CRGYCACGCT	ChIP-seq Contrino et al.(2012) Mv109	0.992	0.992
PAX5 M09341_2.00	Homo sapiens	SNVDGNKCARCVRAGCRDGAC	GTCHYGCTYBGYTGMNCHBNS	Misc Kulakovskiy et al.(2013) PAX5_HUMAN.H11MO.0.A	0.992	0.992
Pax5 M09342_2.00	Mus musculus	VDRNBCAVYVRDSCRKRRM	KYYMYGSHYBRBTGVNYHB	Misc Kulakovskiy et al.(2013) PAX5_MOUSE.H11MO.0.A	0.984	0.984
PAX5 M09622_2.00	Homo sapiens	BCASYSRDSCRTGRMN	NKYCAYGSHYSRSTGV	Misc Heinz et al.(2010) GM12878-PAX5_GSE32465_1	0.984	0.984
PAX5 M09623_2.00	Homo sapiens	BCABNVRSCGTGAC	GTCACGSYBNVTGV	Misc Heinz et al.(2010) GM12878-PAX5_GSE32465_2	0.984	0.984
PAX5 M11208_2.00	Homo sapiens	BCNNNRNKCANBGNWGNRKRGMSRSHNB	VNDSYSKCYMYNCWNCVNTGMNYNNNGV	Transfac Matys et al.(2006) V$PAX5_01	0.984	0.984
PAX5 M11209_2.00	Homo sapiens	VRHVDGDNDBBTNRAGCGKRACVRYNVH	DBNRYBGTYMCGCTYNAVVHNHCHBDYB	Transfac Matys et al.(2006) V$PAX5_02	0.992	0.992
PAX5 M11210_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$PAX5_06	0.992	0.992
PAX5 M11211_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$PAX5_07	0.992	0.992
PAX5 M11212_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$PAX5_Q6	0.984	0.984
pax2 M02428_2.00	Xenopus tropicalis	NNNRNBCRNN	NNYGVNYNNN	PBM Weirauch et al.(2014) pTH8556	0.976	0.976
pax2b M02425_2.00	Danio rerio	HVNYSRNSCR	YGSNYSRNBD	PBM Weirauch et al.(2014) pTH8679	0.968	0.968
PAX8 M05685_2.00	Homo sapiens	NRNBYRNYSRWGCGTGACSN	NSGTCACGCWYSRNYRVNYN	SELEX Yin et al.(2017) PAX8_FL_HT-SELEX	0.944	0.944
Pax8 M09624_2.00	Rattus norvegicus	BCAGBCADSCRKGVM	KBCMYGSHTGVCTGV	Misc Heinz et al.(2010) Thyroid-Pax8_GSE26938	0.936	0.936
PAX8 M11205_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$PAX8_01	0.936	0.936
PAX8 M11206_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$PAX8_B	0.936	0.936
PAX8 M05686_2.00	Homo sapiens	NRNBCRNTSAWSCGYGACNN	NNGTCRCGSWTSANYGVNYN	SELEX Yin et al.(2017) PAX8_FL_Methyl-HT-SELEX	0.944	0.944
sv M01302_2.00	Drosophila melanogaster	NNNSCRBRDM	KHYVYGSNNN	PBM Lambert et al.(2019) pTH9773	0.880	0.880
sv M03949_2.00	Drosophila melanogaster	NBCRNYSAWGCGTGACS	SGTCACGCWTSRNYGVN	SELEX Nitta et al.(2015) sv_1	0.880	0.880
sv M06438_2.00	Drosophila melanogaster	RNYSRDSCGTRACNN	NNGTYACGSHYSRNY	B1H Zhu et al.(2011) sv_SOLEXA_5_FBgn0005561	0.872	0.872
egl-38 M02426_2.00	Caenorhabditis elegans	ACCGTGAYCAC	GTGRTCACGGT	PBM Weirauch et al.(2014) pTH8981	0.752	0.752
pax-2 M00706_2.00	Caenorhabditis elegans	RMSCRTRACS	SGTYAYGSKY	PBM Narasimhan et al.(2015) pTH10794	0.752	0.752
PAX1 M03442_2.00	Homo sapiens	DBCANTSAWGCGTGACS	SGTCACGCWTSANTGVH	SELEX Jolma et al.(2013) PAX1_1	0.744	0.744
PAX7 M00346_2.00	Homo sapiens	NGTYAYGSHN	NDSCRTRACN	PBM Barrera et al.(2016) PAX7_REF	0.744	0.744
PAX9 M03444_2.00	Homo sapiens	NKCANTSAWGCGTGACS	SGTCACGCWTSANTGMN	SELEX Jolma et al.(2013) PAX9_1	0.744	0.744
Poxm M03944_2.00	Drosophila melanogaster	CAVTCAWGCGTGACR	YGTCACGCWTGABTG	SELEX Nitta et al.(2015) Poxm_1	0.744	0.744
Poxm M03945_2.00	Drosophila melanogaster	NYSAWGCRTRACS	SGTYAYGCWTSRN	SELEX Nitta et al.(2015) Poxm_2	0.744	0.744
PAX1 M05687_2.00	Homo sapiens	BCRNTSRWGCGTGACSN	NSGTCACGCWYSANYGV	SELEX Yin et al.(2017) PAX1_eDBD_HT-SELEX	0.744	0.744
PAX9 M05689_2.00	Homo sapiens	BHRNYSRDSCGTRACSN	NSGTYACGSHYSRNYDV	SELEX Yin et al.(2017) PAX9_eDBD_HT-SELEX	0.744	0.744
Poxm M06436_2.00	Drosophila melanogaster	NNNNNNMVNHNRNSCRTGA	TCAYGSNYNDNBKNNNNNN	B1H Zhu et al.(2011) Poxm_SOLEXA_5_FBgn0003129	0.744	0.744
PAX1 M11207_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$PAX1_B	0.744	0.744
PAX1 M05688_2.00	Homo sapiens	BCRNTSAWGCGTGACSN	NSGTCACGCWTSANYGV	SELEX Yin et al.(2017) PAX1_eDBD_Methyl-HT-SELEX	0.744	0.744
PAX9 M05690_2.00	Homo sapiens	BCRNTSAWSCGYGACNN	NNGTCRCGSWTSANYGV	SELEX Yin et al.(2017) PAX9_eDBD_Methyl-HT-SELEX	0.744	0.744
pax9 M11204_2.00	Danio rerio	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$PAX9_B	0.736	0.736
Poxn M03946_2.00	Drosophila melanogaster	DGCGTGACSGTCACGSY	RSCGTGACSGTCACGCH	SELEX Nitta et al.(2015) Poxn_1	0.736	0.736
Poxn M03947_2.00	Drosophila melanogaster	RSCGKGACSGTTMCGSW	WSCGKAACSGTCMCGSY	SELEX Nitta et al.(2015) Poxn_2	0.736	0.736
Poxn M03948_2.00	Drosophila melanogaster	NCGTTCCGGAACGD	HCGTTCCGGAACGN	SELEX Nitta et al.(2015) Poxn_3	0.736	0.736
Poxn M06437_2.00	Drosophila melanogaster	RSCGTGACG	CGTCACGSY	B1H Zhu et al.(2011) Poxn_SOLEXA_5_FBgn0003130	0.736	0.736
PAX7 M00345_2.00	Homo sapiens	NSGTCACGSN	NSCGTGACSN	PBM Barrera et al.(2016) PAX7_P112L	0.728	0.728
For this family, TFs with SR scores > 0.700* will likely have a similar motif*

DNA Binding Domains

Protein ID	Domain	From	To	Sequence
ENSDARP00000071460	Paired box	19	143	GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSSINRIIR
ENSDARP00000071466	Paired box	15	139	RHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSSINRIIR
ENSDARP00000112529	Paired box	15	139	RHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSSINRIIR
ENSDARP00000113404	Paired box	15	139	RHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSSINRIIR
ENSDARP00000115771	Paired box	5	129	GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSSINRIIR
ENSDARP00000119623	Paired box	5	129	GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSSINRIIR
ENSDARP00000121417	Paired box	15	139	RHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSSINRIIR
ENSDARP00000123397	Paired box	5	129	GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSSINRIIR
ENSDARP00000123540	Paired box	5	129	GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSSINRIIR
ENSDARP00000131368	Paired box	19	143	WHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSSINRIIR
ENSDARP00000134011	Paired box	15	139	RHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSSINRIIR

Links
Other Paired box family TFs
Other *Danio rerio* TFs

653 Related TFs

Name	Species	Gene ID	Motif Evidence	SR Score	Action
scaffold498-EXSNAP2012.10	Pristionchus exspectatus	scaffold498-EXSNAP2012.10	N
scaffold56-EXSNAP2012.28	Pristionchus exspectatus	scaffold56-EXSNAP2012.28	N

pax2a (Danio rerio) Paired box

TF Information

Directly determined binding motifs

Motifs from related TFs

DNA Binding Domains

Links

653 Related TFs

pax2a **(Danio rerio)
Paired box**