Cucsa.162720 (Cucumis sativus)
AP2

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00847 (AP2) IPR001471 Cucsa.162720 T007045_2.00 JGI (2012-Mar-17)

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
ERF003
M06667_2.00 		Arabidopsis thaliana
DYCDCCRCCGYMDHHDYHN
NDRHDDHKRCGGYGGHGRH		 Dap-seq
OMalley et al.(2016)
ESE3_col_a 		0.857 0.980
ERF003
M06668_2.00 		Arabidopsis thaliana
HDYCKCCGCCGYHDH
DHDRCGGCGGMGRHD		 Dap-seq
OMalley et al.(2016)
ESE3_colamp_a 		0.857 0.980
WIN1
M01603_2.00 		Arabidopsis thaliana
VCRCCGCNNN
NNNGCGGYGB		 PBM
Weirauch et al.(2014)
pTH7566 		0.727 0.824
For this family, TFs with SR scores > 0.677 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
Cucsa.162720.1 AP2 6 57

Links

Other AP2 family TFs
Other Cucumis sativus TFs

298 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
AB06770.1 Alternaria brassicicola AB06770.1 N 0.000
M378DRAFT_197822 Amanita muscaria M378DRAFT_197822 I 0.000
ARB_03015 Arthroderma benhamiae ARB_03015 I 0.000
MCYG_05833 Arthroderma otae MCYG_05833 I 0.000
e_gw1.00710.51.1 Aspergillus carbonarius e_gw1.00710.51.1 I 0.000
e_gw1.00771.80.1 Aspergillus carbonarius e_gw1.00771.80.1 I 0.000
fgenesh1_pm.00168_#_452 Aspergillus carbonarius fgenesh1_pm.00168_#_452 I 0.000
ACLA_002350 Aspergillus clavatus CADACLAG00000323 I 0.000
ACLA_014120 Aspergillus clavatus CADACLAG00001395 I 0.000
CADAFLAG00007096 Aspergillus flavus CADAFLAG00007096 I 0.000
CADAFLAG00012297 Aspergillus flavus CADAFLAG00012297 I 0.000
AFUA_5G02800 Aspergillus fumigatus CADAFUAG00002739 I 0.000
AFUA_5G01460 Aspergillus fumigatus CADAFUAG00002865 N 0.000
AFUA_5G11070 Aspergillus fumigatus CADAFUAG00005917 I 0.000
ANIA_05691 Aspergillus nidulans CADANIAG00003374 I 0.000
ANIA_05870 Aspergillus nidulans CADANIAG00007168 I 0.000
ANIA_06846 Aspergillus nidulans CADANIAG00007644 D 0.000
CADANGAG00000212 Aspergillus niger CADANGAG00000212 I 0.000
CADAORAG00004258 Aspergillus oryzae CADAORAG00004258 I 0.000
CADAORAG00008529 Aspergillus oryzae CADAORAG00008529 N 0.000
CADAORAG00008740 Aspergillus oryzae CADAORAG00008740 I 0.000
EURHEDRAFT_226967 Aspergillus ruber EURHEDRAFT_226967 I 0.000
EURHEDRAFT_417798 Aspergillus ruber EURHEDRAFT_417798 I 0.000
EURHEDRAFT_528519 Aspergillus ruber EURHEDRAFT_528519 I 0.000
ATEG_07690 Aspergillus terreus CADATEAG00003243 I 0.000
M437DRAFT_14692 Aureobasidium melanogenum M437DRAFT_14692 I 0.000
M437DRAFT_56308 Aureobasidium melanogenum M437DRAFT_56308 I 0.000
M438DRAFT_317248 Aureobasidium pullulans M438DRAFT_317248 I 0.000
M438DRAFT_323991 Aureobasidium pullulans M438DRAFT_323991 I 0.000
M438DRAFT_344531 Aureobasidium pullulans M438DRAFT_344531 I 0.000
M438DRAFT_64434 Aureobasidium pullulans M438DRAFT_64434 I 0.000
AUEXF2481DRAFT_24415 Aureobasidium subglaciale AUEXF2481DRAFT_24415 I 0.000
AUEXF2481DRAFT_4029 Aureobasidium subglaciale AUEXF2481DRAFT_4029 I 0.000
AUEXF2481DRAFT_456199 Aureobasidium subglaciale AUEXF2481DRAFT_456199 I 0.000
BAUCODRAFT_124270 Baudoinia compniacensis BAUCODRAFT_124270 I 0.000
BAUCODRAFT_79055 Baudoinia compniacensis BAUCODRAFT_79055 I 0.000
BBA_07071 Beauveria bassiana BBA_07071 I 0.000
BBA_09836 Beauveria bassiana BBA_09836 I 0.000
COCC4DRAFT_19355 Bipolaris maydis COCC4DRAFT_19355 I 0.000
COCC4DRAFT_44681 Bipolaris maydis COCC4DRAFT_44681 N 0.000
COCMIDRAFT_1482 Bipolaris oryzae COCMIDRAFT_1482 N 0.000
COCMIDRAFT_22555 Bipolaris oryzae COCMIDRAFT_22555 I 0.000
COCMIDRAFT_24418 Bipolaris oryzae COCMIDRAFT_24418 I 0.000
COCSADRAFT_158429 Bipolaris sorokiniana COCSADRAFT_158429 N 0.000
COCSADRAFT_306311 Bipolaris sorokiniana COCSADRAFT_306311 I 0.000
COCVIDRAFT_20649 Bipolaris victoriae COCVIDRAFT_20649 I 0.000
COCCADRAFT_32122 Bipolaris zeicola COCCADRAFT_32122 I 0.000
BDDG_02031 Blastomyces dermatitidis BDDG_02031 I 0.000
BDDG_06193 Blastomyces dermatitidis BDDG_06193 I 0.000
BGHDH14_bgh01598 Blumeria graminis BGHDH14_bgh01598 I 0.000
Bcin04g01240 Botrytis cinerea Bcin04g01240 I 0.000
Bcin08g00170 Botrytis cinerea Bcin08g00170 I 0.000
Bcin10g01580 Botrytis cinerea Bcin10g01580 I 0.000
Bcin12g03530 Botrytis cinerea Bcin12g03530 I 0.000
PVAR5_3215 Byssochlamys spectabilis PVAR5_3215 I 0.000
PVAR5_3228 Byssochlamys spectabilis PVAR5_3228 I 0.000
PVAR5_5942 Byssochlamys spectabilis PVAR5_5942 I 0.000
PVAR5_6880 Byssochlamys spectabilis PVAR5_6880 I 0.000
CaO19.1168 Candida albicans CaO19.1168 I 0.000
CaO19.8761 Candida albicans CaO19.8761 I 0.000
CD36_10810 Candida dubliniensis CD36_10810 I 0.000
G210_5732 Candida maltosa G210_5732 I 0.000
CTRG_03493 Candida tropicalis CTRG_03493 I 0.000
A1O1_02670 Capronia coronata A1O1_02670 I 0.000
A1O1_04263 Capronia coronata A1O1_04263 I 0.000
A1O3_01522 Capronia epimyces A1O3_01522 N 0.000
A1O3_05241 Capronia epimyces A1O3_05241 I 0.000
A1O3_07754 Capronia epimyces A1O3_07754 I 0.000
PV04_00855 Capronia semiimmersa PV04_00855 I 0.000
PV04_09333 Capronia semiimmersa PV04_09333 I 0.000
CERSUDRAFT_114532 Ceriporiopsis subvermispora CERSUDRAFT_114532 I 0.000
CHGG_04995 Chaetomium globosum CHGG_04995 I 0.000
Z519_08538 Cladophialophora bantiana Z519_08538 I 0.000
G647_00858 Cladophialophora carrionii G647_00858 I 0.000
G647_01190 Cladophialophora carrionii G647_01190 I 0.000
G647_07724 Cladophialophora carrionii G647_07724 I 0.000
G647_09400 Cladophialophora carrionii G647_09400 N 0.000
PV07_00458 Cladophialophora immunda PV07_00458 I 0.000
PV07_01614 Cladophialophora immunda PV07_01614 I 0.000
A1O5_01272 Cladophialophora psammophila A1O5_01272 I 0.000
A1O7_01132 Cladophialophora yegresii A1O7_01132 I 0.000
A1O7_08749 Cladophialophora yegresii A1O7_08749 I 0.000
CIMG_00672 Coccidioides immitis CIMG_00672 I 0.000
CIMG_04661 Coccidioides immitis CIMG_04661 I 0.000
CPC735_055980 Coccidioides posadasii CPC735_055980 I 0.000
estExt_fgenesh1_pg.C_40169 Cochliobolus heterostrophus C5 estExt_fgenesh1_pg.C_40169 I 0.000
CFIO01_03805 Colletotrichum fioriniae CFIO01_03805 I 0.000
CFIO01_07975 Colletotrichum fioriniae CFIO01_07975 I 0.000
CGGC5_10057 Colletotrichum gloeosporioides CGGC5_10057 N 0.000
CGGC5_14706 Colletotrichum gloeosporioides CGGC5_14706 I 0.000
CGGC5_2205 Colletotrichum gloeosporioides CGGC5_2205 I 0.000
CGGC5_3013 Colletotrichum gloeosporioides CGGC5_3013 I 0.000
GLRG_00281 Colletotrichum graminicola GLRG_00281 I 0.000
GLRG_05692 Colletotrichum graminicola GLRG_05692 I 0.000
GLRG_09907 Colletotrichum graminicola GLRG_09907 I 0.000
Cob_02318 Colletotrichum orbiculare Cob_02318 I 0.000
Cob_02984 Colletotrichum orbiculare Cob_02984 I 0.000
CSUB01_02738 Colletotrichum sublineola CSUB01_02738 I 0.000
CSUB01_04709 Colletotrichum sublineola CSUB01_04709 I 0.000
CSUB01_12509 Colletotrichum sublineola CSUB01_12509 I 0.000
W97_00313 Coniosporium apollinis W97_00313 I 0.000
W97_02535 Coniosporium apollinis W97_02535 I 0.000
e_gw1.3.1267.1 Cryphonectria parasitica e_gw1.3.1267.1 I 0.000
e_gw1.3.1365.1 Cryphonectria parasitica e_gw1.3.1365.1 I 0.000
HMPREF1541_03778 Cyphellophora europaea HMPREF1541_03778 I 0.000
HMPREF1541_05887 Cyphellophora europaea HMPREF1541_05887 I 0.000
DEHA2C03058g Debaryomyces hansenii DEHA2C03058g I 0.000
DOTSEDRAFT_158220 Dothistroma septosporum DOTSEDRAFT_158220 I 0.000
DOTSEDRAFT_68677 Dothistroma septosporum DOTSEDRAFT_68677 N 0.000
EPUS_00566 Endocarpon pusillum EPUS_00566 I 0.000
A1O9_01837 Exophiala aquamarina A1O9_01837 I 0.000
A1O9_03442 Exophiala aquamarina A1O9_03442 N 0.000
A1O9_09993 Exophiala aquamarina A1O9_09993 I 0.000
HMPREF1120_01122 Exophiala dermatitidis HMPREF1120_01122 I 0.000
HMPREF1120_07945 Exophiala dermatitidis HMPREF1120_07945 N 0.000
HMPREF1120_08148 Exophiala dermatitidis HMPREF1120_08148 I 0.000
PV10_02783 Exophiala mesophila PV10_02783 I 0.000
PV10_04981 Exophiala mesophila PV10_04981 I 0.000
PV10_06359 Exophiala mesophila PV10_06359 I 0.000
PV06_05113 Exophiala oligosperma PV06_05113 I 0.000
PV06_07392 Exophiala oligosperma PV06_07392 I 0.000
PV06_08141 Exophiala oligosperma PV06_08141 I 0.000
PV11_00348 Exophiala sideris PV11_00348 I 0.000
PV11_02421 Exophiala sideris PV11_02421 I 0.000
PV11_05636 Exophiala sideris PV11_05636 N 0.000
PV08_06966 Exophiala spinifera PV08_06966 I 0.000
PV08_09084 Exophiala spinifera PV08_09084 I 0.000
PV05_00782 Exophiala xenobiotica PV05_00782 I 0.000
PV05_03582 Exophiala xenobiotica PV05_03582 I 0.000
PV05_09226 Exophiala xenobiotica PV05_09226 I 0.000
FIBRA_03539 Fibroporia radiculosa FIBRA_03539 I 0.000
FOMPIDRAFT_1024907 Fomitopsis pinicola FOMPIDRAFT_1024907 I 0.000
Z517_01546 Fonsecaea pedrosoi Z517_01546 I 0.000
Z517_04525 Fonsecaea pedrosoi Z517_04525 I 0.000
FFUJ_09638 Fusarium fujikuroi FFUJ_09638 I 0.000
FGRRES_02854 Fusarium graminearum FGRRES_02854 I 0.000
FGRRES_16137 Fusarium graminearum FGRRES_16137 I 0.000
FOXG_11440 Fusarium oxysporum FOXG_11440 I 0.000
FPSE_10395 Fusarium pseudograminearum FPSE_10395 I 0.000
NechaG43849 Fusarium solani NechaG43849 I 0.000
NechaG46033 Fusarium solani NechaG46033 I 0.000
FVEG_10380 Fusarium verticillioides FVEG_10380 I 0.000
GGTG_03357 Gaeumannomyces graminis GGTG_03357 I 0.000
GGTG_05803 Gaeumannomyces graminis GGTG_05803 I 0.000
GALMADRAFT_249209 Galerina marginata GALMADRAFT_249209 I 0.000
M413DRAFT_441943 Hebeloma cylindrosporum M413DRAFT_441943 I 0.000
HCBG_04888 Histoplasma capsulatum HCBG_04888 I 0.000
JAAARDRAFT_136956 Jaapia argillacea JAAARDRAFT_136956 I 0.000
LEMA_P120870.1 Leptosphaeria maculans LEMA_P120870.1 I 0.000
MGG_01887 Magnaporthe oryzae MGG_01887 I 0.000
MGG_05153 Magnaporthe oryzae MGG_05153 I 0.000
MGG_07131 Magnaporthe oryzae MGG_07131 I 0.000
MAPG_01428 Magnaporthe poae MAPG_01428 I 0.000
MAPG_04101 Magnaporthe poae MAPG_04101 I 0.000
MBM_00253 Marssonina brunnea MBM_00253 I 0.000
MAC_00726 Metarhizium acridum MAC_00726 N 0.000
MAC_02441 Metarhizium acridum MAC_02441 I 0.000
MAC_04259 Metarhizium acridum MAC_04259 I 0.000
MAM_03911 Metarhizium album MAM_03911 N 0.000
MANI_020691 Metarhizium anisopliae MANI_020691 N 0.000
MBR_00349 Metarhizium brunneum MBR_00349 N 0.000
MGU_01192 Metarhizium guizhouense MGU_01192 N 0.000
MAJ_01716 Metarhizium majus MAJ_01716 N 0.000
X797_005336 Metarhizium robertsii X797_005336 N 0.000
X797_005471 Metarhizium robertsii X797_005471 I 0.000
X797_008651 Metarhizium robertsii X797_008651 I 0.000
MCYG_03627 Microsporum canis MCYG_03627 I 0.000
MCYG_05833 Microsporum canis MCYG_05833 I 0.000
MGYG_03225 Microsporum gypseum MGYG_03225 I 0.000
MGYG_06143 Microsporum gypseum MGYG_06143 I 0.000
Moror_6819 Moniliophthora roreri Moror_6819 I 0.000
gw1.10.415.1 Mycosphaerella fijiensis gw1.10.415.1 I 0.000
estExt_Genewise1Plus.C_chr_11826 Mycosphaerella graminicola estExt_Genewise1Plus.C_chr_11826 N 0.000
gw1.9.126.1 Mycosphaerella graminicola gw1.9.126.1 I 0.000
e_gw1.17.466.1 Nectria haematococca e_gw1.17.466.1 I 0.000
e_gw1.20.1180.1 Nectria haematococca e_gw1.20.1180.1 I 0.000
UCRNP2_1133 Neofusicoccum parvum UCRNP2_1133 N 0.000
UCRNP2_6646 Neofusicoccum parvum UCRNP2_6646 I 0.000
NFIA_040650 Neosartorya fischeri CADNFIAG00003354 I 0.000
NFIA_039290 Neosartorya fischeri CADNFIAG00003792 I 0.000
NFIA_076190 Neosartorya fischeri CADNFIAG00007846 I 0.000
NCU00017 Neurospora crassa NCU00017 D 0.000
NCU08658 Neurospora crassa NCU08658 D 0.000
estExt_fgenesh2_pg.C_30094 Neurospora discreta estExt_fgenesh2_pg.C_30094 I 0.000
estExt_fgenesh3_pm.C_50537 Neurospora discreta estExt_fgenesh3_pm.C_50537 I 0.000
NEUTE1DRAFT_129586 Neurospora tetrasperma NEUTE1DRAFT_129586 I 0.000
NEUTE1DRAFT_39574 Neurospora tetrasperma NEUTE1DRAFT_39574 I 0.000
HPODL_02161 Ogataea parapolymorpha HPODL_02161 I 0.000
OIDMADRAFT_109168 Oidiodendron maius OIDMADRAFT_109168 I 0.000
OIDMADRAFT_42277 Oidiodendron maius OIDMADRAFT_42277 I 0.000
OIDMADRAFT_45534 Oidiodendron maius OIDMADRAFT_45534 I 0.000
OIDMADRAFT_57009 Oidiodendron maius OIDMADRAFT_57009 I 0.000
OCS_01600 Ophiocordyceps sinensis OCS_01600 I 0.000
F503_05786 Ophiostoma piceae uamh F503_05786 I 0.000
F503_05814 Ophiostoma piceae uamh F503_05814 I 0.000
PABG_04832 Paracoccidioides brasiliensis PABG_04832 I 0.000
PAAG_02331 Paracoccidioides sp lutzii PAAG_02331 I 0.000
PAXRUDRAFT_132889 Paxillus rubicundulus PAXRUDRAFT_132889 I 0.000
Pc12g14900 Penicillium chrysogenum Pc12g14900 I 0.000
Pc21g05540 Penicillium chrysogenum Pc21g05540 I 0.000
PDIP_60970 Penicillium digitatum PDIP_60970 I 0.000
PEX1_066340 Penicillium expansum PEX1_066340 I 0.000
PEX1_087000 Penicillium expansum PEX1_087000 I 0.000
PITC_033600 Penicillium italicum PITC_033600 I 0.000
PITC_054700 Penicillium italicum PITC_054700 I 0.000
PMAA_014320 Penicillium marneffei PMAA_014320 N 0.000
PMAA_033170 Penicillium marneffei PMAA_033170 I 0.000
PMAA_041870 Penicillium marneffei PMAA_041870 I 0.000
PDE_07596 Penicillium oxalicum PDE_07596 I 0.000
PDE_08558 Penicillium oxalicum PDE_08558 I 0.000
PDE_09179 Penicillium oxalicum PDE_09179 I 0.000
PCH_Pc12g14900 Penicillium rubens PCH_Pc12g14900 I 0.000
PCH_Pc21g05540 Penicillium rubens PCH_Pc21g05540 I 0.000
U727_0043114071 Penicillium solitum U727_0043114071 I 0.000
U727_00434270371 Penicillium solitum U727_00434270371 I 0.000
SNOG_09854 Phaeosphaeria nodorum SNOG_09854 I 0.000
PILCRDRAFT_51 Piloderma croceum PILCRDRAFT_51 I 0.000
PISMIDRAFT_675317 Pisolithus microcarpus PISMIDRAFT_675317 I 0.000
M404DRAFT_130508 Pisolithus tinctorius M404DRAFT_130508 I 0.000
PLEOSDRAFT_158391 Pleurotus ostreatus PLEOSDRAFT_158391 I 0.000
MYCFIDRAFT_107799 Pseudocercospora fijiensis MYCFIDRAFT_107799 I 0.000
GMDG_04293 Pseudogymnoascus destructans GMDG_04293 I 0.000
V499_01659 Pseudogymnoascus pannorum V499_01659 I 0.000
PTT_16310 Pyrenophora teres PTT_16310 I 0.000
PTRG_07169 Pyrenophora triticirepentis PTRG_07169 I 0.000
Z518_05201 Rhinocladiella mackenziei Z518_05201 I 0.000
V565_106980 Rhizoctonia solani V565_106980 N 0.000
SAPIO_CDS8046 Scedosporium apiospermum SAPIO_CDS8046 I 0.000
SPOG_02829 Schizosaccharomyces cryophilus SPOG_02829 I 0.000
SBOR_6101 Sclerotinia borealis SBOR_6101 I 0.000
SBOR_6332 Sclerotinia borealis SBOR_6332 I 0.000
SBOR_8674 Sclerotinia borealis SBOR_8674 I 0.000
SERLA73DRAFT_159962 Serpula lacrymans SERLA73DRAFT_159962 I 0.000
SETTUDRAFT_166718 Setosphaeria turcica SETTUDRAFT_166718 N 0.000
SMAC_03743 Sordaria macrospora SMAC_03743 I 0.000
SPAPADRAFT_61489 Spathaspora passalidarum SPAPADRAFT_61489 I 0.000
SEPMUDRAFT_92213 Sphaerulina musiva SEPMUDRAFT_92213 I 0.000
S40288_05491 Stachybotrys chartarum S40288_05491 I 0.000
S40288_10288 Stachybotrys chartarum S40288_10288 I 0.000
S40285_03475 Stachybotrys chlorohalonata S40285_03475 I 0.000
SNOG_00909 Stagonospora nodorum SNOG_00909 I 0.000
SNOG_09854 Stagonospora nodorum SNOG_09854 I 0.000
PMAA_014320 Talaromyces marneffei PMAA_014320 N 0.000
PMAA_033170 Talaromyces marneffei PMAA_033170 I 0.000
PMAA_041870 Talaromyces marneffei PMAA_041870 I 0.000
TSTA_020390 Talaromyces stipitatus TSTA_020390 I 0.000
TSTA_064390 Talaromyces stipitatus TSTA_064390 I 0.000
TSTA_076120 Talaromyces stipitatus TSTA_076120 I 0.000
TSTA_122850 Talaromyces stipitatus TSTA_122850 I 0.000
THITE_11494 Thielavia terrestris THITE_11494 I 0.000
BN946_scf184775.g19 Trametes cinnabarina BN946_scf184775.g19 N 0.000
fgeneshTM_pg.13_#_14 Tremella mesenterica fgeneshTM_pg.13_#_14 N 0.000
TRIATDRAFT_13008 Trichoderma atroviride TRIATDRAFT_13008 I 0.000
TRIREDRAFT_53106 Trichoderma reesei TRIREDRAFT_53106 I 0.000
TRIREDRAFT_55274 Trichoderma reesei TRIREDRAFT_55274 I 0.000
TRIVIDRAFT_133401 Trichoderma virens TRIVIDRAFT_133401 I 0.000
TRIVIDRAFT_55531 Trichoderma virens TRIVIDRAFT_55531 I 0.000
TEQG_01335 Trichophyton equinum TEQG_01335 I 0.000
TEQG_06790 Trichophyton equinum TEQG_06790 I 0.000
H101_03862 Trichophyton interdigitale H101_03862 I 0.000
H101_04164 Trichophyton interdigitale H101_04164 I 0.000
H102_03722 Trichophyton rubrum H102_03722 I 0.000
H105_03749 Trichophyton soudanense H105_03749 I 0.000
TESG_05486 Trichophyton tonsurans TESG_05486 I 0.000
TESG_06981 Trichophyton tonsurans TESG_06981 I 0.000
TRV_01730 Trichophyton verrucosum TRV_01730 I 0.000
UREG_00669 Uncinocarpus reesii UREG_00669 I 0.000
PV09_06702 Verruconis gallopava PV09_06702 I 0.000
VDBG_02399 Verticillium albo atrum VDBG_02399 I 0.000
VDBG_02399 Verticillium alfalfae VDBG_02399 I 0.000
VDAG_00765 Verticillium dahliae VDAG_00765 I 0.000
VDAG_08992 Verticillium dahliae VDAG_08992 I 0.000
VDAG_10186 Verticillium dahliae VDAG_10186 I 0.000
YALI0_D23045g Yarrowia lipolytica YALI0_D23045g I 0.000
Mycgr3G11650 Zymoseptoria tritici Mycgr3G11650 I 0.000
Mycgr3G66114 Zymoseptoria tritici Mycgr3G66114 N 0.000