TFEC (Homo sapiens)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00010 (HLH) IPR001092 ENSG00000105967 T034258_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
TFEC
M02778_2.00		 Homo sapiens
RNCACRTGAB
VTCAYGTGNY		 SELEX
Jolma et al.(2013)
TFEC_1		 (Direct) (Direct)
TFEC
M04078_2.00		 Homo sapiens
NVCACGTGACN
NGTCACGTGBN		 SELEX
Yin et al.(2017)
TFEC_eDBD_HT-SELEX		 (Direct) (Direct)
TFEC
M04079_2.00		 Homo sapiens
VNCATGTGAYN
NRTCACATGNB		 SELEX
Yin et al.(2017)
TFEC_eDBD_Methyl-HT-SELEX		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Tfec
M00755_2.00 		Mus musculus
NNCACGTGNN
NNCACGTGNN		 PBM
Weirauch et al.(2013)
pTH2885 		0.914 0.981
Tfec
M01736_2.00 		Mus musculus
NCNCRTGVYN
NRBCAYGNGN		 PBM
Weirauch et al.(2014)
pTH5065 		0.914 0.981
Mitf
M01741_2.00 		Mus musculus
NCDCGTGAYN
NRTCACGHGN		 PBM
Weirauch et al.(2014)
pTH5465 		0.870 0.907
MITF
M08058_2.00 		Homo sapiens
NNNDRTCACGTGAYHNNN
NNNDRTCACGTGAYHNNN		 ChIP-seq
Mathelier et al.(2014)
MA0620.2 		0.870 0.907
MITF
M08740_2.00 		Homo sapiens
YCAYGTGACH
DGTCACRTGR		 Misc
Kulakovskiy et al.(2013)
MITF_HUMAN.H11MO.0.A 		0.870 0.907
Mitf
M08765_2.00 		Mus musculus
BCHYGTGACY
RGTCACRDGV		 Misc
Kulakovskiy et al.(2013)
MITF_MOUSE.H11MO.0.A 		0.870 0.907
Mitf
M09475_2.00 		Mus musculus
GTCACRWGVB
VBCWYGTGAC		 Misc
Heinz et al.(2010)
MastCells-MITF_GSE48085 		0.870 0.907
MITF
M09880_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$MITF_Q4 		0.870 0.907
MITF
M09881_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$MITF_Q6 		0.870 0.907
Tfe3
M01715_2.00 		Mus musculus
NCDCRTGAYN
NRTCAYGHGN		 PBM
Weirauch et al.(2014)
pTH5057 		0.870 0.889
Tfe3
M05833_2.00 		Mus musculus
CACGTGAY
RTCACGTG		 SMiLE-seq
Isakova et al.(2017)
TFE3 		0.870 0.889
Tfe3
M08743_2.00 		Mus musculus
TCACGTGACH
DGTCACGTGA		 Misc
Kulakovskiy et al.(2013)
TFE3_MOUSE.H11MO.0.A 		0.870 0.889
Tfe3
M09884_2.00 		Mus musculus Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TFEA_01 		0.870 0.889
For this family, TFs with SR scores > 0.838 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000265440 bHLH 140 193
ENSP00000318676 bHLH 111 164
ENSP00000377125 bHLH 111 164
ENSP00000387650 bHLH 73 126
ENSP00000417432 bHLH 230 283

Links

Other bHLH family TFs
Other Homo sapiens TFs

149 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ACYPI003652 Acyrthosiphon pisum ACYPI003652 N 0.000
AAEL010472 Aedes aegypti AAEL010472 I 0.000
ENSAMEG00000000014 Ailuropoda melanoleuca ENSAMEG00000000014 I 0.000
ENSAMEG00000012594 Ailuropoda melanoleuca ENSAMEG00000012594 I 0.000
Alligator_sinensis_CCG019028.1 Alligator sinensis Alligator_sinensis_CCG019028.1 I 0.000
ENSAPLG00000000896 Anas platyrhynchos ENSAPLG00000000896 I 0.000
ENSACAG00000005980 Anolis carolinensis ENSACAG00000005980 I 0.000
ENSACAG00000017046 Anolis carolinensis ENSACAG00000017046 I 0.000
AALB003178 Anopheles albimanus AALB003178 I 0.000
AARA011500 Anopheles arabiensis AARA011500 I 0.000
ACHR000367 Anopheles christyi ACHR000367 I 0.000
ACOM033000 Anopheles coluzzii ACOM033000 I 0.000
ACUA016345 Anopheles culicifacies ACUA016345 I 0.000
ADIR002616 Anopheles dirus ADIR002616 I 0.000
AEPI003935 Anopheles epiroticus AEPI003935 I 0.000
AFAF009626 Anopheles farauti AFAF009626 I 0.000
AFUN001469 Anopheles funestus AFUN001469 I 0.000
AMAM004582 Anopheles maculatus AMAM004582 I 0.000
AMEC016032 Anopheles melas AMEC016032 I 0.000
AMEM008015 Anopheles merus AMEM008015 I 0.000
AMIN002999 Anopheles minimus AMIN002999 I 0.000
ASTEI11387 Anopheles stephensi ASTEI11387 I 0.000
GB40906 Apis mellifera GB40906 I 0.000
ENSAMXG00000011388 Astyanax mexicanus ENSAMXG00000011388 I 0.000
ENSAMXG00000017924 Astyanax mexicanus ENSAMXG00000017924 I 0.000
ACEP26870 Atta cephalotes ACEP26870 I 0.000
BGLB003718 Biomphalaria glabrata BGLB003718 I 0.000
BGIBMGA013959 Bombyx mori BGIBMGA013959 I 0.000
ENSBTAP00000025739-D1 Bos grunniens ENSBTAP00000025739-D1 I 0.000
ENSP00000360950-D1 Bos grunniens ENSP00000360950-D1 I 0.000
TAL1 Bos taurus ENSBTAG00000005029 I 0.000
LYL1 Bos taurus ENSBTAG00000019329 I 0.000
gw.349.31.1 Branchiostoma floridae gw.349.31.1 I 0.000
Brh_R008908 Buceros rhinoceros Brh_R008908 I 0.000
TAL1 Callithrix jacchus ENSCJAG00000021222 I 0.000
Aan_R000747 Calypte anna Aan_R000747 I 0.000
Cflo_01951--XP_001121011.1_APIME Camponotus floridanus Cflo_01951--XP_001121011.1_APIME I 0.000
TAL1 Canis familiaris ENSCAFG00000004032 I 0.000
CapteG49381 Capitella teleta CapteG49381 I 0.000
ENSCPOG00000003558 Cavia porcellus ENSCPOG00000003558 I 0.000
ENSCPOG00000024157 Cavia porcellus ENSCPOG00000024157 I 0.000
Cmyd_10006869 Chelonia mydas Cmyd_10006869 I 0.000
ENSCSAG00000001247 Chlorocebus sabaeus ENSCSAG00000001247 I 0.000
ENSCSAG00000006504 Chlorocebus sabaeus ENSCSAG00000006504 I 0.000
CpipJ_CPIJ014602 Culex pipiens CpipJ_CPIJ014602 I 0.000
CPIJ014602 Culex quinquefasciatus CPIJ014602 I 0.000
KGM_01922 Danaus plexippus KGM_01922 I 0.000
tal1 Danio rerio ENSDARG00000019930 I 0.000
CABZ01066696.1 Danio rerio ENSDARG00000091603 I 0.000
ENSDNOG00000043562 Dasypus novemcinctus ENSDNOG00000043562 I 0.000
TAL1 Dasypus novemcinctus ENSDNOG00000047501 I 0.000
ENSDORG00000004570 Dipodomys ordii ENSDORG00000004570 I 0.000
GF21374 Drosophila ananassae FBgn0098376 I 0.000
GG18617 Drosophila erecta FBgn0110828 I 0.000
GH24106 Drosophila grimshawi FBgn0131562 I 0.000
HLH3B Drosophila melanogaster FBgn0011276 I 0.000
GI14376 Drosophila mojavensis FBgn0137128 I 0.000
GL26737 Drosophila persimilis FBgn0164318 I 0.000
GA15411 Drosophila pseudoobscura FBgn0075429 I 0.000
GD24607 Drosophila simulans FBgn0195935 I 0.000
GJ19415 Drosophila virilis FBgn0206558 I 0.000
GK10268 Drosophila willistoni FBgn0212283 I 0.000
GE16932 Drosophila yakuba FBgn0234420 I 0.000
ENSETEG00000008816 Echinops telfairi ENSETEG00000008816 I 0.000
ENSECAG00000018746 Equus caballus ENSECAG00000018746 I 0.000
ENSFCAG00000031106 Felis catus ENSFCAG00000031106 I 0.000
ENSFALG00000009303 Ficedula albicollis ENSFALG00000009303 I 0.000
ENSGMOG00000005856 Gadus morhua ENSGMOG00000005856 I 0.000
TAL1 Gallus gallus ENSGALG00000023296 I 0.000
tal1 Gasterosteus aculeatus ENSGACG00000013846 I 0.000
tal1 Gasterosteus aculeatus ENSGACG00000019476 I 0.000
Gfo_R009231 Geospiza fortis Gfo_R009231 I 0.000
TAL1 Gorilla gorilla ENSGGOG00000011776 I 0.000
LYL1 Gorilla gorilla ENSGGOG00000023512 I 0.000
HHAL006178-PA Halyomorpha halys HHAL006178-PA N 0.000
Hsal_07700--XP_001121011.1_APIME Harpegnathos saltator Hsal_07700--XP_001121011.1_APIME I 0.000
HelroG81338 Helobdella robusta HelroG81338 I 0.000
LYL1 Homo sapiens ENSG00000104903 D 0.000
TAL1 Homo sapiens ENSG00000162367 D 0.000
ENSSTOG00000008396 Ictidomys tridecemlineatus ENSSTOG00000008396 I 0.000
ENSSTOG00000028401 Ictidomys tridecemlineatus ENSSTOG00000028401 I 0.000
ISCW010324 Ixodes scapularis ISCW010324 I 0.000
ENSLACG00000011366 Latimeria chalumnae ENSLACG00000011366 I 0.000
ENSLACG00000017036 Latimeria chalumnae ENSLACG00000017036 I 0.000
ENSLOCG00000007669 Lepisosteus oculatus ENSLOCG00000007669 I 0.000
ENSLOCG00000009966 Lepisosteus oculatus ENSLOCG00000009966 I 0.000
LDEC012804 Leptinotarsa decemlineata LDEC012804 I 0.000
LotgiG59839 Lottia gigantea LotgiG59839 N 0.000
LYL1 Loxodonta africana ENSLAFG00000005235 I 0.000
TAL1 Loxodonta africana ENSLAFG00000013880 I 0.000
LCUP012404 Lucilia cuprina LCUP012404 N 0.000
LLOJ006043 Lutzomyia longipalpis LLOJ006043 I 0.000
ENSP00000360950 Macaca fascicularis ENSP00000360950 I 0.000
LYL1 Macaca mulatta ENSMMUG00000001166 I 0.000
ENSMMUG00000017870 Macaca mulatta ENSMMUG00000017870 I 0.000
ENSMEUG00000008559 Macropus eugenii ENSMEUG00000008559 I 0.000
ENSMEUG00000011615 Macropus eugenii ENSMEUG00000011615 I 0.000
ENSMGAG00000010823 Meleagris gallopavo ENSMGAG00000010823 I 0.000
MCINX015509 Melitaea cinxia MCINX015509 I 0.000
TAL1 Monodelphis domestica ENSMODG00000001502 I 0.000
LYL1 Monodelphis domestica ENSMODG00000011593 I 0.000
MDOA013066 Musca domestica MDOA013066 N 0.000
ENSMPUG00000004316 Mustela putorius furo ENSMPUG00000004316 I 0.000
ENSMPUG00000012410 Mustela putorius furo ENSMPUG00000012410 I 0.000
Tal1 Mus musculus ENSMUSG00000028717 D 0.000
Myotis_brandtii_LYL1_10009227 Myotis brandtii Myotis_brandtii_LYL1_10009227 I 0.000
Myotis_brandtii_TAL1_10003055 Myotis brandtii Myotis_brandtii_TAL1_10003055 I 0.000
ENSMLUG00000006388 Myotis lucifugus ENSMLUG00000006388 I 0.000
LYL1 Myotis lucifugus ENSMLUG00000012805 I 0.000
NV24799 Nasonia vitripennis NV24799 I 0.000
ENSNLEG00000013010 Nomascus leucogenys ENSNLEG00000013010 I 0.000
ENSNLEG00000016398 Nomascus leucogenys ENSNLEG00000016398 I 0.000
TAL1 Ochotona princeps ENSOPRG00000004033 I 0.000
Ogr06402 Ophisaurus gracilis Ogr06402 I 0.000
Ogr13537 Ophisaurus gracilis Ogr13537 I 0.000
ENSONIG00000009960 Oreochromis niloticus ENSONIG00000009960 I 0.000
ENSONIG00000018071 Oreochromis niloticus ENSONIG00000018071 I 0.000
LYL1 Ornithorhynchus anatinus ENSOANG00000006846 I 0.000
ENSOANG00000032005 Ornithorhynchus anatinus ENSOANG00000032005 I 0.000
TAL1 Oryctolagus cuniculus ENSOCUG00000017248 I 0.000
tal1 Oryzias latipes ENSORLG00000003776 I 0.000
ENSORLG00000013953 Oryzias latipes ENSORLG00000013953 I 0.000
tal1 Oryzias latipes ENSORLG00000016044 I 0.000
ENSOGAG00000016551 Otolemur garnettii ENSOGAG00000016551 I 0.000
LYL1 Otolemur garnettii ENSOGAG00000033339 I 0.000
ENSOARG00000003450 Ovis aries ENSOARG00000003450 I 0.000
ENSOARG00000009454 Ovis aries ENSOARG00000009454 I 0.000
TAL1 Pan troglodytes ENSPTRG00000000710 I 0.000
ENSPANG00000009893 Papio anubis ENSPANG00000009893 I 0.000
ENSPANG00000014670 Papio anubis ENSPANG00000014670 I 0.000
PHUM038940 Pediculus humanus PHUM038940 N 0.000
ENSPSIG00000010614 Pelodiscus sinensis ENSPSIG00000010614 I 0.000
ENSPMAG00000002259 Petromyzon marinus ENSPMAG00000002259 I 0.000
ENSPFOG00000005195 Poecilia formosa ENSPFOG00000005195 I 0.000
ENSPFOG00000013394 Poecilia formosa ENSPFOG00000013394 I 0.000
Pvit_02813 Pogona vitticeps Pvit_02813 I 0.000
Pvit_14582 Pogona vitticeps Pvit_14582 I 0.000
ENSPPYG00000009621 Pongo abelii ENSPPYG00000009621 I 0.000
LYL1 Procavia capensis ENSPCAG00000003676 I 0.000
TAL1 Procavia capensis ENSPCAG00000006179 I 0.000
ENSPVAG00000005351 Pteropus vampyrus ENSPVAG00000005351 I 0.000
LYL1 Pteropus vampyrus ENSPVAG00000015075 I 0.000
Tal1 Rattus norvegicus ENSRNOG00000025051 I 0.000
RPRC000013 Rhodnius prolixus RPRC000013 N 0.000
ENSSHAG00000010681 Sarcophilus harrisii ENSSHAG00000010681 I 0.000
ENSSHAG00000014421 Sarcophilus harrisii ENSSHAG00000014421 I 0.000
SINV21956 Solenopsis invicta SINV21956 I 0.000
SMAR000405 Strigamia maritima SMAR000405 I 0.000
ENSSSCG00000013743 Sus scrofa ENSSSCG00000013743 I 0.000
ENSSSCG00000026460 Sus scrofa ENSSSCG00000026460 I 0.000
TAL1 Taeniopygia guttata ENSTGUG00000008542 I 0.000
ENSTRUG00000004487 Takifugu rubripes ENSTRUG00000004487 I 0.000
tal1 Takifugu rubripes ENSTRUG00000008218 I 0.000
tal1 Tetraodon nigroviridis ENSTNIG00000001525 I 0.000
tal1 Tetraodon nigroviridis ENSTNIG00000006133 I 0.000
TC009117 Tribolium castaneum TC009117 I 0.000
LYL1 Tursiops truncatus ENSTTRG00000006376 I 0.000
TAL1 Tursiops truncatus ENSTTRG00000011653 I 0.000
TAL1 Vicugna pacos ENSVPAG00000004268 I 0.000
tal1.S Xenopus laevis XB-GENE-865312 I 0.000
tal1 Xenopus tropicalis XB-GENE-479827 I 0.000
lyl1 Xenopus tropicalis XB-GENE-940268 I 0.000
ENSXMAG00000007215 Xiphophorus maculatus ENSXMAG00000007215 I 0.000
ENSXMAG00000015686 Xiphophorus maculatus ENSXMAG00000015686 I 0.000
L798_06639 Zootermopsis nevadensis L798_06639 I 0.000