ARNTL (Homo sapiens)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00010 (HLH) IPR001092 ENSG00000133794 T034285_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
ARNTL
M02787_2.00		 Homo sapiens
GTCACGTGAC
GTCACGTGAC		 SELEX
Jolma et al.(2013)
ARNTL_1		 (Direct) (Direct)
ARNTL
M04124_2.00		 Homo sapiens
RDCACGTGHN
NDCACGTGHY		 SELEX
Yin et al.(2017)
ARNTL_eDBD_HT-SELEX		 (Direct) (Direct)
ARNTL
M04125_2.00		 Homo sapiens
NDCACRTGHY
RDCAYGTGHN		 SELEX
Yin et al.(2017)
ARNTL_eDBD_Methyl-HT-SELEX		 (Direct) (Direct)
ARNTL
M08725_2.00		 Homo sapiens
NVDCACGTGBN
NVCACGTGHBN		 Misc
Kulakovskiy et al.(2013)
BMAL1_HUMAN.H11MO.0.A		 (Direct) (Direct)
ARNTL
M09841_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$BMAL1_Q6		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Arntl
M01751_2.00 		Mus musculus
NCACGTGAYN
NRTCACGTGN		 PBM
Weirauch et al.(2014)
pTH5064 		0.914 1.000
Arntl
M08776_2.00 		Mus musculus
VCACGTGMN
NKCACGTGB		 Misc
Kulakovskiy et al.(2013)
BMAL1_MOUSE.H11MO.0.A 		0.914 1.000
Arntl
M09478_2.00 		Mus musculus
CACGTGNN
NNCACGTG		 Misc
Heinz et al.(2010)
Liver-Bmal1_GSE39860 		0.914 1.000
Arntl
M09889_2.00 		Rattus norvegicus Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$BMAL1_01 		0.826 1.000
For this family, TFs with SR scores > 0.838 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000374357 bHLH 73 126
ENSP00000384517 bHLH 73 126
ENSP00000385581 bHLH 30 83
ENSP00000385897 bHLH 71 124
ENSP00000385915 bHLH 30 83
ENSP00000431488 bHLH 73 100
ENSP00000433571 bHLH 73 126
ENSP00000434263 bHLH 30 46
ENSP00000436313 bHLH 30 83
ENSP00000436721 bHLH 30 72

Links

Other bHLH family TFs
Other Homo sapiens TFs

97 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ACYPI001442 Acyrthosiphon pisum ACYPI001442 I
ACYPI006937 Acyrthosiphon pisum ACYPI006937 I
ACYPI007541 Acyrthosiphon pisum ACYPI007541 I
AAEL006160 Aedes aegypti AAEL006160 I
AAEL006167 Aedes aegypti AAEL006167 I
AAEL007040 Aedes aegypti AAEL007040 I
ENSAMEG00000005325 Ailuropoda melanoleuca ENSAMEG00000005325 I
ENSAMEG00000010102 Ailuropoda melanoleuca ENSAMEG00000010102 I
Alligator_sinensis_CCG001676.1 Alligator sinensis Alligator_sinensis_CCG001676.1 I
ENSAPLG00000016439 Anas platyrhynchos ENSAPLG00000016439 I
RUNX2 Anolis carolinensis ENSACAG00000013003 I
AALB007752 Anopheles albimanus AALB007752 I
AALB007754 Anopheles albimanus AALB007754 I
AALB009220 Anopheles albimanus AALB009220 I
AARA004356 Anopheles arabiensis AARA004356 I
AARA011332 Anopheles arabiensis AARA011332 I
AARA011472 Anopheles arabiensis AARA011472 I
AATE002063 Anopheles atroparvus AATE002063 I
AATE017340 Anopheles atroparvus AATE017340 I
ACHR004078 Anopheles christyi ACHR004078 I
ACHR006341 Anopheles christyi ACHR006341 I
ACOM031089 Anopheles coluzzii ACOM031089 I
ACUA016618 Anopheles culicifacies ACUA016618 I
ADIR005600 Anopheles dirus ADIR005600 I
AEPI003479 Anopheles epiroticus AEPI003479 I
AEPI010884 Anopheles epiroticus AEPI010884 I
AFAF000166 Anopheles farauti AFAF000166 I
AFUN010423 Anopheles funestus AFUN010423 I
AGAP001094 Anopheles gambiae AGAP001094 I
AGAP002506 Anopheles gambiae AGAP002506 I
AMAM016300 Anopheles maculatus AMAM016300 I
AMEC007551 Anopheles melas AMEC007551 I
AMEC011614 Anopheles melas AMEC011614 I
AMEM004753 Anopheles merus AMEM004753 I
AMEM017856 Anopheles merus AMEM017856 I
AMIN002518 Anopheles minimus AMIN002518 I
AMIN005759 Anopheles minimus AMIN005759 I
AQUA009970 Anopheles quadriannulatus AQUA009970 I
ASIS001308 Anopheles sinensis ASIS001308 I
ASTEI07770 Anopheles stephensi ASTEI07770 I
ASTEI07771 Anopheles stephensi ASTEI07771 I
ASTEI07959 Anopheles stephensi ASTEI07959 I
GB52718 Apis mellifera GB52718 I
GB52719 Apis mellifera GB52719 I
GB52721 Apis mellifera GB52721 I
GB52761 Apis mellifera GB52761 I
ENSAMXG00000000881 Astyanax mexicanus ENSAMXG00000000881 I
ENSAMXG00000004048 Astyanax mexicanus ENSAMXG00000004048 I
ENSAMXG00000012244 Astyanax mexicanus ENSAMXG00000012244 I
ENSAMXG00000017349 Astyanax mexicanus ENSAMXG00000017349 I
BGIBMGA008906 Bombyx mori BGIBMGA008906 I
ENSP00000409227-D1 Bos grunniens ENSP00000409227-D1 I
RUNX2 Bos taurus ENSBTAG00000004104 I
RUNX1 Bos taurus ENSBTAG00000004742 I
estExt_fgenesh2_kg.C_3770001 Branchiostoma floridae estExt_fgenesh2_kg.C_3770001 I
estExt_fgenesh2_kg.C_750001 Branchiostoma floridae estExt_fgenesh2_kg.C_750001 I
RUNX1 Callithrix jacchus ENSCJAG00000002816 I
RUNX3 Callithrix jacchus ENSCJAG00000020815 I
Cflo_03909--XP_394016.2_APIME Camponotus floridanus Cflo_03909--XP_394016.2_APIME I
Cflo_03910--XP_001121886.1_APIME Camponotus floridanus Cflo_03910--XP_001121886.1_APIME I
Cflo_03911--XP_394014.2_APIME Camponotus floridanus Cflo_03911--XP_394014.2_APIME I
Cflo_03913--XP_394013.3_APIME Camponotus floridanus Cflo_03913--XP_394013.3_APIME I
RUNX1 Canis familiaris ENSCAFG00000009596 I
RUNX3 Canis familiaris ENSCAFG00000012903 I
CapteG142159 Capitella teleta CapteG142159 I
ENSCPOG00000000551 Cavia porcellus ENSCPOG00000000551 I
ENSCPOG00000002684 Cavia porcellus ENSCPOG00000002684 I
RUNX2 Cavia porcellus ENSCPOG00000005277 I
Cmyd_10020455 Chelonia mydas Cmyd_10020455 I
Cmyd_10020845 Chelonia mydas Cmyd_10020845 I
Cmyd_10021516 Chelonia mydas Cmyd_10021516 I
ENSCSAG00000000947 Chlorocebus sabaeus ENSCSAG00000000947 I
ENSCSAG00000008703 Chlorocebus sabaeus ENSCSAG00000008703 I
ENSCSAG00000012528 Chlorocebus sabaeus ENSCSAG00000012528 I
CLEC011122 Cimex lectularius CLEC011122 I
CGI_10005366 Crassostrea gigas CGI_10005366 I
CpipJ_CPIJ001309 Culex pipiens CpipJ_CPIJ001309 I
CPIJ001309 Culex quinquefasciatus CPIJ001309 I
KGM_21067 Danaus plexippus KGM_21067 I
KGM_21075 Danaus plexippus KGM_21075 I
runx2a Danio rerio ENSDARG00000040261 I
runx3 Danio rerio ENSDARG00000052826 I
runx2b Danio rerio ENSDARG00000059233 I
DAPPUDRAFT_290554 Daphnia pulex DAPPUDRAFT_290554 I
DAPPUDRAFT_290555 Daphnia pulex DAPPUDRAFT_290555 I
DAPPUDRAFT_290557 Daphnia pulex DAPPUDRAFT_290557 I
RUNX1 Dasypus novemcinctus ENSDNOG00000015041 I
RUNX2 Dasypus novemcinctus ENSDNOG00000034361 I
RUNX3 Dasypus novemcinctus ENSDNOG00000043493 I
YQE_12218 Dendroctonus ponderosae YQE_12218 I
Runx1 Dipodomys ordii ENSDORG00000004347 I
GF15967 Drosophila ananassae FBgn0092990 I
GF15970 Drosophila ananassae FBgn0092993 I
GF15983 Drosophila ananassae FBgn0093006 I
run Drosophila erecta FBgn0085118 I
GG17578 Drosophila erecta FBgn0109803 I
GG18309 Drosophila erecta FBgn0110525 I
GG19691 Drosophila erecta FBgn0111893 I
GH17737 Drosophila grimshawi FBgn0125207 I
GH17740 Drosophila grimshawi FBgn0125210 I
GH17774 Drosophila grimshawi FBgn0125244 I
lz Drosophila melanogaster FBgn0002576 D
run Drosophila melanogaster FBgn0003300 D
RunxA Drosophila melanogaster FBgn0083981 I
RunxB Drosophila melanogaster FBgn0259162 I
GI14398 Drosophila mojavensis FBgn0137150 I
GI15119 Drosophila mojavensis FBgn0137869 I
GI15491 Drosophila mojavensis FBgn0138240 I
GL15800 Drosophila persimilis FBgn0153404 I
GL15806 Drosophila persimilis FBgn0153410 I
GL15927 Drosophila persimilis FBgn0153531 I
GL16499 Drosophila persimilis FBgn0154103 I
run Drosophila pseudoobscura FBgn0013862 I
GA13742 Drosophila pseudoobscura FBgn0073778 I
GA22609 Drosophila pseudoobscura FBgn0244012 I
GA25684 Drosophila pseudoobscura FBgn0247061 I
GM22478 Drosophila sechellia FBgn0177348 I
GM23044 Drosophila sechellia FBgn0177912 I
GM23050 Drosophila sechellia FBgn0177918 I
run Drosophila simulans FBgn0016352 I
GD16951 Drosophila simulans FBgn0188530 I
GD17495 Drosophila simulans FBgn0189047 I
run Drosophila virilis FBgn0013920 I
GJ18742 Drosophila virilis FBgn0205894 I
GJ18917 Drosophila virilis FBgn0206063 I
GJ19245 Drosophila virilis FBgn0206390 I
GK19810 Drosophila willistoni FBgn0221808 I
GK19815 Drosophila willistoni FBgn0221813 I
GK20052 Drosophila willistoni FBgn0222049 I
GK25373 Drosophila willistoni FBgn0227332 I
run Drosophila yakuba FBgn0084618 I
GE15340 Drosophila yakuba FBgn0232921 I
GE17788 Drosophila yakuba FBgn0235232 I
GE17890 Drosophila yakuba FBgn0235328 I
RUNX1 Equus caballus ENSECAG00000003462 I
RUNX2 Equus caballus ENSECAG00000020875 I
RUNX2 Erinaceus europaeus ENSEEUG00000009243 I
RUNX3 Felis catus ENSFCAG00000000680 I
ENSFALG00000000025 Ficedula albicollis ENSFALG00000000025 I
ENSFALG00000000470 Ficedula albicollis ENSFALG00000000470 I
ENSGMOG00000010468 Gadus morhua ENSGMOG00000010468 I
ENSGMOG00000014088 Gadus morhua ENSGMOG00000014088 I
ENSGMOG00000019132 Gadus morhua ENSGMOG00000019132 I
RUNX1 Gallus gallus ENSGALG00000016022 I
ENSGALG00000026821 Gallus gallus ENSGALG00000026821 I
runx3 Gasterosteus aculeatus ENSGACG00000007301 I
runx2b Gasterosteus aculeatus ENSGACG00000012322 I
RUNX1 Gasterosteus aculeatus ENSGACG00000015276 I
Gfo_R011596 Geospiza fortis Gfo_R011596 I
RUNX3 Gorilla gorilla ENSGGOG00000004848 I
RUNX1 Gorilla gorilla ENSGGOG00000012862 I
RUNX2 Gorilla gorilla ENSGGOG00000012890 I
Hsal_04635--XP_394013.3_APIME Harpegnathos saltator Hsal_04635--XP_394013.3_APIME I
Hsal_12319--XP_394016.2_APIME Harpegnathos saltator Hsal_12319--XP_394016.2_APIME I
Hsal_12321--XP_001121886.1_APIME Harpegnathos saltator Hsal_12321--XP_001121886.1_APIME I
Hsal_12322--XP_394014.2_APIME Harpegnathos saltator Hsal_12322--XP_394014.2_APIME I
RUNX3 Homo sapiens ENSG00000020633 D
RUNX2 Homo sapiens ENSG00000124813 D
RUNX1 Homo sapiens ENSG00000159216 D
ENSSTOG00000010163 Ictidomys tridecemlineatus ENSSTOG00000010163 I
ENSSTOG00000022471 Ictidomys tridecemlineatus ENSSTOG00000022471 I
ISCW004493 Ixodes scapularis ISCW004493 I
ENSLACG00000011545 Latimeria chalumnae ENSLACG00000011545 I
ENSLACG00000013776 Latimeria chalumnae ENSLACG00000013776 I
ENSLACG00000015930 Latimeria chalumnae ENSLACG00000015930 I
ENSLOCG00000002744 Lepisosteus oculatus ENSLOCG00000002744 I
ENSLOCG00000010990 Lepisosteus oculatus ENSLOCG00000010990 I
ENSLOCG00000015816 Lepisosteus oculatus ENSLOCG00000015816 I
LDEC006645 Leptinotarsa decemlineata LDEC006645 I
LotgiG96224 Lottia gigantea LotgiG96224 I
RUNX1 Loxodonta africana ENSLAFG00000004290 I
RUNX3 Loxodonta africana ENSLAFG00000008382 I
LCUP002657 Lucilia cuprina LCUP002657 I
LCUP002659 Lucilia cuprina LCUP002659 I
LLOJ002717 Lutzomyia longipalpis LLOJ002717 I
ENSP00000300305 Macaca fascicularis ENSP00000300305 I
RUNX1 Macaca mulatta ENSMMUG00000001649 I
RUNX3 Macaca mulatta ENSMMUG00000002420 I
RUNX2 Macaca mulatta ENSMMUG00000019819 I
ENSMEUG00000014419 Macropus eugenii ENSMEUG00000014419 I
MESCA007078 Megaselia scalaris MESCA007078 I
MCINX000302 Melitaea cinxia MCINX000302 I
MCINX005906 Melitaea cinxia MCINX005906 I
RUNX1 Microcebus murinus ENSMICG00000011998 I
ENSMODG00000013941 Monodelphis domestica ENSMODG00000013941 I
RUNX2 Monodelphis domestica ENSMODG00000018912 I
RUNX1 Monodelphis domestica ENSMODG00000021051 I
MDOA009046 Musca domestica MDOA009046 I
MDOA010744 Musca domestica MDOA010744 I
MDOA011942 Musca domestica MDOA011942 I
MDOA013149 Musca domestica MDOA013149 I
ENSMPUG00000001340 Mustela putorius furo ENSMPUG00000001340 I
ENSMPUG00000015804 Mustela putorius furo ENSMPUG00000015804 I
Runx1 Mus musculus ENSMUSG00000022952 D
Runx2 Mus musculus ENSMUSG00000039153 D
Runx3 Mus musculus ENSMUSG00000070691 D
Myotis_brandtii_RUNX2_10026084 Myotis brandtii Myotis_brandtii_RUNX2_10026084 I
RUNX3 Myotis lucifugus ENSMLUG00000003395 I
NV10998 Nasonia vitripennis NV10998 I
NV11000 Nasonia vitripennis NV11000 I
NV17759 Nasonia vitripennis NV17759 I
NV17793 Nasonia vitripennis NV17793 I
NEMVEDRAFT_v1g129231 Nematostella vectensis NEMVEDRAFT_v1g129231 I
ENSNLEG00000004310 Nomascus leucogenys ENSNLEG00000004310 I
ENSOPRG00000000765 Ochotona princeps ENSOPRG00000000765 I
RUNX2 Ochotona princeps ENSOPRG00000002943 I
RUNX3 Ochotona princeps ENSOPRG00000011273 I
Ogr17914 Ophisaurus gracilis Ogr17914 I
ENSONIG00000001025 Oreochromis niloticus ENSONIG00000001025 I
ENSONIG00000004914 Oreochromis niloticus ENSONIG00000004914 I
ENSONIG00000008210 Oreochromis niloticus ENSONIG00000008210 I
ENSOANG00000031074 Ornithorhynchus anatinus ENSOANG00000031074 I
RUNX1 Oryctolagus cuniculus ENSOCUG00000013731 I
RUNX3 Oryctolagus cuniculus ENSOCUG00000017751 I
runx2 Oryzias latipes ENSORLG00000010169 I
runx3 Oryzias latipes ENSORLG00000017515 I
RUNX1 Oryzias latipes ENSORLG00000020699 I
RUNX2 Otolemur garnettii ENSOGAG00000003900 I
RUNX3 Otolemur garnettii ENSOGAG00000025633 I
RUNX1 Otolemur garnettii ENSOGAG00000033362 I
ENSOARG00000006421 Ovis aries ENSOARG00000006421 I
RUNX3 Pan troglodytes ENSPTRG00000000351 I
RUNX1 Pan troglodytes ENSPTRG00000013883 I
RUNX2 Pan troglodytes ENSPTRG00000018228 I
ENSPANG00000006186 Papio anubis ENSPANG00000006186 I
ENSPANG00000007357 Papio anubis ENSPANG00000007357 I
ENSPANG00000008140 Papio anubis ENSPANG00000008140 I
PHUM333300 Pediculus humanus PHUM333300 I
PHUM333310 Pediculus humanus PHUM333310 I
PHUM333320 Pediculus humanus PHUM333320 I
PHUM333340 Pediculus humanus PHUM333340 I
ENSPSIG00000012728 Pelodiscus sinensis ENSPSIG00000012728 I
ENSPSIG00000014293 Pelodiscus sinensis ENSPSIG00000014293 I
ENSPSIG00000017547 Pelodiscus sinensis ENSPSIG00000017547 I
PPAI006591 Phlebotomus papatasi PPAI006591 I
PPAI010986 Phlebotomus papatasi PPAI010986 I
ENSPFOG00000003997 Poecilia formosa ENSPFOG00000003997 I
ENSPFOG00000008944 Poecilia formosa ENSPFOG00000008944 I
ENSPFOG00000016115 Poecilia formosa ENSPFOG00000016115 I
Pvit_01165 Pogona vitticeps Pvit_01165 I
Pvit_04762 Pogona vitticeps Pvit_04762 I
Pvit_17193 Pogona vitticeps Pvit_17193 I
ENSPPYG00000001714 Pongo abelii ENSPPYG00000001714 I
ENSPPYG00000011394 Pongo abelii ENSPPYG00000011394 I
ENSPPYG00000016664 Pongo abelii ENSPPYG00000016664 I
RUNX1 Procavia capensis ENSPCAG00000016747 I
RUNX1 Pteropus vampyrus ENSPVAG00000001606 I
Runx1 Rattus norvegicus ENSRNOG00000001704 I
Runx2 Rattus norvegicus ENSRNOG00000020193 I
Runx3 Rattus norvegicus ENSRNOG00000054217 I
RPRC005391 Rhodnius prolixus RPRC005391 I
Sakowv30005496m.g Saccoglossus kowalevskii Sakowv30005496m.g I
ENSSHAG00000009950 Sarcophilus harrisii ENSSHAG00000009950 I
ENSSHAG00000014782 Sarcophilus harrisii ENSSHAG00000014782 I
SINV13317 Solenopsis invicta SINV13317 I
SINV13356 Solenopsis invicta SINV13356 I
SINV13363 Solenopsis invicta SINV13363 I
SPU_006917 Strongylocentrotus purpuratus SPU_006917 I
SPU_007852 Strongylocentrotus purpuratus SPU_007852 I
ENSSSCG00000012051 Sus scrofa ENSSSCG00000012051 I
RUNX3 Taeniopygia guttata ENSTGUG00000001130 I
ENSTGUG00000004719 Taeniopygia guttata ENSTGUG00000004719 I
RUNX2 Taeniopygia guttata ENSTGUG00000013249 I
runx3 Takifugu rubripes ENSTRUG00000001517 I
runx2 Takifugu rubripes ENSTRUG00000003501 I
runx1 Takifugu rubripes ENSTRUG00000012611 I
ENSTSYG00000005097 Tarsius syrichta ENSTSYG00000005097 I
tetur01g02340 Tetranychus urticae tetur01g02340 I
runx2b Tetraodon nigroviridis ENSTNIG00000009685 I
runx3 Tetraodon nigroviridis ENSTNIG00000016911 I
ENSTNIG00000018690 Tetraodon nigroviridis ENSTNIG00000018690 I
TC005566 Tribolium castaneum TC005566 I
TC005796 Tribolium castaneum TC005796 I
TC006536 Tribolium castaneum TC006536 I
TC006542 Tribolium castaneum TC006542 I
TriadG25179 Trichoplax adhaerens TriadG25179 I
RUNX2 Tursiops truncatus ENSTTRG00000006943 I
RUNX3 Tursiops truncatus ENSTTRG00000009396 I
RUNX1 Tursiops truncatus ENSTTRG00000014160 I
runx3.L Xenopus laevis XB-GENE-6487158 I
runx2.L Xenopus laevis XB-GENE-864817 I
runx1.L Xenopus laevis XB-GENE-864949 I
runx2 Xenopus tropicalis XB-GENE-482021 I
runx3 Xenopus tropicalis XB-GENE-487784 I
XP_002939386 Xenopus tropicalis XP_002939386 I
XP_002939387 Xenopus tropicalis XP_002939387 I
XP_002939388 Xenopus tropicalis XP_002939388 I
ENSXMAG00000003400 Xiphophorus maculatus ENSXMAG00000003400 I
ENSXMAG00000004396 Xiphophorus maculatus ENSXMAG00000004396 I
ENSXMAG00000018835 Xiphophorus maculatus ENSXMAG00000018835 I
L798_10922 Zootermopsis nevadensis L798_10922 I