MITF (Homo sapiens)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00010 (HLH) IPR001092 ENSG00000187098 T034335_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
MITF
M08058_2.00		 Homo sapiens
NNNDRTCACGTGAYHNNN
NNNDRTCACGTGAYHNNN		 ChIP-seq
Mathelier et al.(2014)
MA0620.2		 (Direct) (Direct)
MITF
M08740_2.00		 Homo sapiens
YCAYGTGACH
DGTCACRTGR		 Misc
Kulakovskiy et al.(2013)
MITF_HUMAN.H11MO.0.A		 (Direct) (Direct)
MITF
M09880_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$MITF_Q4		 (Direct) (Direct)
MITF
M09881_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$MITF_Q6		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Mitf
M01741_2.00 		Mus musculus
NCDCGTGAYN
NRTCACGHGN		 PBM
Weirauch et al.(2014)
pTH5465 		0.914 1.000
Mitf
M08765_2.00 		Mus musculus
BCHYGTGACY
RGTCACRDGV		 Misc
Kulakovskiy et al.(2013)
MITF_MOUSE.H11MO.0.A 		0.914 1.000
Mitf
M09475_2.00 		Mus musculus
GTCACRWGVB
VBCWYGTGAC		 Misc
Heinz et al.(2010)
MastCells-MITF_GSE48085 		0.914 1.000
Tfe3
M01715_2.00 		Mus musculus
NCDCRTGAYN
NRTCAYGHGN		 PBM
Weirauch et al.(2014)
pTH5057 		0.914 0.981
Tfe3
M05833_2.00 		Mus musculus
CACGTGAY
RTCACGTG		 SMiLE-seq
Isakova et al.(2017)
TFE3 		0.914 0.981
Tfe3
M08743_2.00 		Mus musculus
TCACGTGACH
DGTCACGTGA		 Misc
Kulakovskiy et al.(2013)
TFE3_MOUSE.H11MO.0.A 		0.914 0.981
Tfe3
M09884_2.00 		Mus musculus Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TFEA_01 		0.914 0.981
TFE3
M02773_2.00 		Homo sapiens
VNCACGTGMY
RKCACGTGNB		 SELEX
Jolma et al.(2013)
TFE3_1 		0.871 0.963
TFE3
M04058_2.00 		Homo sapiens
YVCACGTGAYN
NRTCACGTGBR		 SELEX
Yin et al.(2017)
TFE3_eDBD_HT-SELEX 		0.871 0.963
TFE3
M08709_2.00 		Homo sapiens
TCACGTGACH
DGTCACGTGA		 Misc
Kulakovskiy et al.(2013)
TFE3_HUMAN.H11MO.0.B 		0.871 0.963
TFE3
M09790_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TFEA_Q6 		0.871 0.963
TFE3
M04059_2.00 		Homo sapiens
NRTCACATGBB
VVCATGTGAYN		 SELEX
Yin et al.(2017)
TFE3_eDBD_Methyl-HT-SELEX 		0.871 0.963
Tfec
M00755_2.00 		Mus musculus
NNCACGTGNN
NNCACGTGNN		 PBM
Weirauch et al.(2013)
pTH2885 		0.870 0.926
Tfec
M01736_2.00 		Mus musculus
NCNCRTGVYN
NRBCAYGNGN		 PBM
Weirauch et al.(2014)
pTH5065 		0.870 0.926
TFEC
M02778_2.00 		Homo sapiens
RNCACRTGAB
VTCAYGTGNY		 SELEX
Jolma et al.(2013)
TFEC_1 		0.870 0.907
TFEC
M04078_2.00 		Homo sapiens
NVCACGTGACN
NGTCACGTGBN		 SELEX
Yin et al.(2017)
TFEC_eDBD_HT-SELEX 		0.870 0.907
TFEC
M04079_2.00 		Homo sapiens
VNCATGTGAYN
NRTCACATGNB		 SELEX
Yin et al.(2017)
TFEC_eDBD_Methyl-HT-SELEX 		0.870 0.907
Tfeb
M01728_2.00 		Mus musculus
CWCGTGAY
RTCACGWG		 PBM
Weirauch et al.(2014)
pTH5072 		0.855 0.889
TFEB
M02781_2.00 		Homo sapiens
RNCACGTGAY
RTCACGTGNY		 SELEX
Jolma et al.(2013)
TFEB_1 		0.855 0.889
TFEB
M02727_2.00 		Homo sapiens
RTCACGTGAY
RTCACGTGAY		 SELEX
Jolma et al.(2010)
TFEB_dimer 		0.855 0.889
TFEB
M04088_2.00 		Homo sapiens
YVCACGTGAYN
NRTCACGTGBR		 SELEX
Yin et al.(2017)
TFEB_eDBD_HT-SELEX 		0.855 0.889
TFEB
M08718_2.00 		Homo sapiens
CACGTGAYY
RRTCACGTG		 Misc
Kulakovskiy et al.(2013)
TFEB_HUMAN.H11MO.0.C 		0.855 0.889
Tfeb
M08753_2.00 		Mus musculus
CACGTGAYY
RRTCACGTG		 Misc
Kulakovskiy et al.(2013)
TFEB_MOUSE.H11MO.0.C 		0.855 0.889
TFEB
M04089_2.00 		Homo sapiens
VNCATGTGAYN
NRTCACATGNB		 SELEX
Yin et al.(2017)
TFEB_eDBD_Methyl-HT-SELEX 		0.855 0.889
For this family, TFs with SR scores > 0.838 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000295600 bHLH 306 359
ENSP00000324246 bHLH 199 252
ENSP00000324443 bHLH 290 343
ENSP00000327867 bHLH 305 358
ENSP00000377880 bHLH 205 258
ENSP00000391803 bHLH 312 365
ENSP00000398639 bHLH 296 349
ENSP00000418845 bHLH 254 307
ENSP00000435909 bHLH 143 196

Links

Other bHLH family TFs
Other Homo sapiens TFs

243 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ENSAMEG00000003595 Ailuropoda melanoleuca ENSAMEG00000003595 I
ENSAMEG00000008438 Ailuropoda melanoleuca ENSAMEG00000008438 I
Alligator_sinensis_CCG011357.1 Alligator sinensis Alligator_sinensis_CCG011357.1 I
Alligator_sinensis_CCG011722.1 Alligator sinensis Alligator_sinensis_CCG011722.1 I
ENSAPLG00000002486 Anas platyrhynchos ENSAPLG00000002486 I
ENSAPLG00000004662 Anas platyrhynchos ENSAPLG00000004662 I
BACH1 Anolis carolinensis ENSACAG00000001974 I
BACH2 Anolis carolinensis ENSACAG00000014366 I
Afo_R004850 Aptenodytes forsteri Afo_R004850 I
Afo_R005014 Aptenodytes forsteri Afo_R005014 I
ENSAMXG00000008686 Astyanax mexicanus ENSAMXG00000008686 I
ENSAMXG00000014356 Astyanax mexicanus ENSAMXG00000014356 I
ENSAMXG00000015064 Astyanax mexicanus ENSAMXG00000015064 I
ENSAMXG00000020851 Astyanax mexicanus ENSAMXG00000020851 I
ENSBTAP00000005416-D1 Bos grunniens ENSBTAP00000005416-D1 I
ENSBTAP00000027603-D1 Bos grunniens ENSBTAP00000027603-D1 I
BACH1 Bos taurus ENSBTAG00000004139 I
BACH2 Bos taurus ENSBTAG00000020713 I
Brh_R002617 Buceros rhinoceros Brh_R002617 I
Brh_R008770 Buceros rhinoceros Brh_R008770 I
BACH2 Callithrix jacchus ENSCJAG00000001013 I
BACH1 Callithrix jacchus ENSCJAG00000008651 I
Aan_R001177 Calypte anna Aan_R001177 I
Aan_R007355 Calypte anna Aan_R007355 I
BACH2 Canis familiaris ENSCAFG00000003116 I
BACH1 Canis familiaris ENSCAFG00000008729 I
BACH1 Cavia porcellus ENSCPOG00000008737 I
ENSCPOG00000009261 Cavia porcellus ENSCPOG00000009261 I
Cmyd_10011594 Chelonia mydas Cmyd_10011594 I
Cmyd_10020811 Chelonia mydas Cmyd_10020811 I
ENSCSAG00000009211 Chlorocebus sabaeus ENSCSAG00000009211 I
ENSCSAG00000017273 Chlorocebus sabaeus ENSCSAG00000017273 I
BACH1 Choloepus hoffmanni ENSCHOG00000008331 I
bach1b Danio rerio ENSDARG00000002196 I
bach2b Danio rerio ENSDARG00000004074 I
bach2a Danio rerio ENSDARG00000036569 I
bach1a Danio rerio ENSDARG00000062553 I
BACH1 Dasypus novemcinctus ENSDNOG00000034053 I
BACH2 Dasypus novemcinctus ENSDNOG00000042939 I
ENSDORG00000003106 Dipodomys ordii ENSDORG00000003106 I
BACH1 Echinops telfairi ENSETEG00000017222 I
BACH1 Equus caballus ENSECAG00000000307 I
BACH2 Equus caballus ENSECAG00000010522 I
BACH2 Erinaceus europaeus ENSEEUG00000001063 I
BACH1 Erinaceus europaeus ENSEEUG00000011474 I
BACH2 Felis catus ENSFCAG00000008901 I
BACH1 Felis catus ENSFCAG00000010547 I
ENSFALG00000003160 Ficedula albicollis ENSFALG00000003160 I
ENSFALG00000006318 Ficedula albicollis ENSFALG00000006318 I
ENSGMOG00000002053 Gadus morhua ENSGMOG00000002053 I
ENSGMOG00000002062 Gadus morhua ENSGMOG00000002062 I
ENSGMOG00000009808 Gadus morhua ENSGMOG00000009808 I
ENSGMOG00000015765 Gadus morhua ENSGMOG00000015765 I
BACH2 Gallus gallus ENSGALG00000015605 I
BACH1 Gallus gallus ENSGALG00000015828 I
bach2a Gasterosteus aculeatus ENSGACG00000002017 I
bach2b Gasterosteus aculeatus ENSGACG00000006245 I
bach1a Gasterosteus aculeatus ENSGACG00000011798 I
Gfo_R007851 Geospiza fortis Gfo_R007851 I
Gfo_R008348 Geospiza fortis Gfo_R008348 I
BACH1 Gorilla gorilla ENSGGOG00000006094 I
BACH2 Gorilla gorilla ENSGGOG00000012497 I
BACH2 Homo sapiens ENSG00000112182 D
BACH1 Homo sapiens ENSG00000156273 D
ENSSTOG00000003942 Ictidomys tridecemlineatus ENSSTOG00000003942 I
ENSSTOG00000005129 Ictidomys tridecemlineatus ENSSTOG00000005129 I
ENSLACG00000001994 Latimeria chalumnae ENSLACG00000001994 I
ENSLACG00000003435 Latimeria chalumnae ENSLACG00000003435 I
ENSLOCG00000009077 Lepisosteus oculatus ENSLOCG00000009077 I
ENSLOCG00000016952 Lepisosteus oculatus ENSLOCG00000016952 I
BACH1 Loxodonta africana ENSLAFG00000029492 I
ENSP00000286800 Macaca fascicularis ENSP00000286800 I
ENSP00000345642 Macaca fascicularis ENSP00000345642 I
BACH2 Macaca mulatta ENSMMUG00000009736 I
BACH1 Macaca mulatta ENSMMUG00000011095 I
ENSMEUG00000000125 Macropus eugenii ENSMEUG00000000125 I
ENSMEUG00000016322 Macropus eugenii ENSMEUG00000016322 I
BACH2 Meleagris gallopavo ENSMGAG00000013626 I
BACH1 Meleagris gallopavo ENSMGAG00000014508 I
ENSMICG00000005097 Microcebus murinus ENSMICG00000005097 I
BACH2 Monodelphis domestica ENSMODG00000018176 I
BACH1 Monodelphis domestica ENSMODG00000020976 I
ENSMPUG00000001053 Mustela putorius furo ENSMPUG00000001053 I
ENSMPUG00000009102 Mustela putorius furo ENSMPUG00000009102 I
Bach1 Mus musculus ENSMUSG00000025612 D
Bach2 Mus musculus ENSMUSG00000040270 D
Myotis_brandtii_BACH1_10005484 Myotis brandtii Myotis_brandtii_BACH1_10005484 I
Myotis_brandtii_Bach2_10023882 Myotis brandtii Myotis_brandtii_Bach2_10023882 I
BACH2 Myotis lucifugus ENSMLUG00000001651 I
ENSNLEG00000003356 Nomascus leucogenys ENSNLEG00000003356 I
ENSNLEG00000013316 Nomascus leucogenys ENSNLEG00000013316 I
BACH1 Ochotona princeps ENSOPRG00000003937 I
BACH2 Ochotona princeps ENSOPRG00000008266 I
Ogr00706 Ophisaurus gracilis Ogr00706 I
Ogr07752 Ophisaurus gracilis Ogr07752 I
ENSONIG00000001606 Oreochromis niloticus ENSONIG00000001606 I
ENSONIG00000004708 Oreochromis niloticus ENSONIG00000004708 I
ENSONIG00000005635 Oreochromis niloticus ENSONIG00000005635 I
BACH1 Ornithorhynchus anatinus ENSOANG00000005242 I
BACH2 Oryctolagus cuniculus ENSOCUG00000004231 I
BACH1 Oryctolagus cuniculus ENSOCUG00000016716 I
bach1a Oryzias latipes ENSORLG00000003339 I
ENSORLG00000004475 Oryzias latipes ENSORLG00000004475 I
bach2a Oryzias latipes ENSORLG00000011098 I
bach2b Oryzias latipes ENSORLG00000017926 I
BACH1 Otolemur garnettii ENSOGAG00000012819 I
BACH2 Otolemur garnettii ENSOGAG00000024390 I
ENSOARG00000012361 Ovis aries ENSOARG00000012361 I
ENSOARG00000014393 Ovis aries ENSOARG00000014393 I
BACH1 Pan troglodytes ENSPTRG00000013824 I
BACH2 Pan troglodytes ENSPTRG00000018426 I
ENSPANG00000006817 Papio anubis ENSPANG00000006817 I
ENSPANG00000007661 Papio anubis ENSPANG00000007661 I
ENSPSIG00000009237 Pelodiscus sinensis ENSPSIG00000009237 I
ENSPSIG00000016485 Pelodiscus sinensis ENSPSIG00000016485 I
ENSPMAG00000005517 Petromyzon marinus ENSPMAG00000005517 I
ENSPFOG00000002681 Poecilia formosa ENSPFOG00000002681 I
ENSPFOG00000009427 Poecilia formosa ENSPFOG00000009427 I
ENSPFOG00000013310 Poecilia formosa ENSPFOG00000013310 I
ENSPFOG00000017325 Poecilia formosa ENSPFOG00000017325 I
Pvit_09321 Pogona vitticeps Pvit_09321 I
Pvit_10701 Pogona vitticeps Pvit_10701 I
ENSPPYG00000011322 Pongo abelii ENSPPYG00000011322 I
ENSPPYG00000016849 Pongo abelii ENSPPYG00000016849 I
BACH2 Procavia capensis ENSPCAG00000001355 I
BACH1 Pteropus vampyrus ENSPVAG00000003585 I
BACH2 Pteropus vampyrus ENSPVAG00000016152 I
Bach1 Rattus norvegicus ENSRNOG00000001582 I
Bach2 Rattus norvegicus ENSRNOG00000006170 I
ENSSHAG00000006419 Sarcophilus harrisii ENSSHAG00000006419 I
ENSSHAG00000016295 Sarcophilus harrisii ENSSHAG00000016295 I
BACH1 Sorex araneus ENSSARG00000010869 I
BACH2 Sus scrofa ENSSSCG00000004332 I
BACH1 Sus scrofa ENSSSCG00000012029 I
BACH2 Taeniopygia guttata ENSTGUG00000012380 I
BACH1 Taeniopygia guttata ENSTGUG00000013585 I
ENSTRUG00000009007 Takifugu rubripes ENSTRUG00000009007 I
bach1a Takifugu rubripes ENSTRUG00000014936 I
ENSTSYG00000009578 Tarsius syrichta ENSTSYG00000009578 I
ENSTSYG00000010694 Tarsius syrichta ENSTSYG00000010694 I
ENSTNIG00000001421 Tetraodon nigroviridis ENSTNIG00000001421 I
bach2b Tetraodon nigroviridis ENSTNIG00000003864 I
bach1a Tetraodon nigroviridis ENSTNIG00000019024 I
BACH2 Tupaia belangeri ENSTBEG00000008433 I
BACH1 Tupaia belangeri ENSTBEG00000010199 I
BACH2 Tursiops truncatus ENSTTRG00000003941 I
Tal_R000432 Tyto alba Tal_R000432 I
BACH1 Vicugna pacos ENSVPAG00000012419 I
bach1 Xenopus tropicalis XB-GENE-957116 I
bach2 Xenopus tropicalis XB-GENE-994313 I
ENSXMAG00000007309 Xiphophorus maculatus ENSXMAG00000007309 I
ENSXMAG00000013761 Xiphophorus maculatus ENSXMAG00000013761 I
ENSXMAG00000014429 Xiphophorus maculatus ENSXMAG00000014429 I
ENSXMAG00000017662 Xiphophorus maculatus ENSXMAG00000017662 I