srebf2.L (Xenopus laevis)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00010 (HLH) IPR001092 XB-GENE-1011364 T051762_2.00 Misc (2018-Jan-19)

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Srebf2
M01725_2.00 		Mus musculus
TSRCGTGA
TCACGYSA		 PBM
Weirauch et al.(2014)
pTH4327 		0.914 0.961
SREBF2
M02811_2.00 		Homo sapiens
RTCACGTGAY
RTCACGTGAY		 SELEX
Jolma et al.(2013)
SREBF2_1 		0.914 0.961
SREBF2
M03591_2.00 		Homo sapiens
NRTCACVCCAYH
DRTGGBGTGAYN		 SELEX
Nitta et al.(2015)
SREBF2_1 		0.914 0.961
SREBF2
M04219_2.00 		Homo sapiens
RTCACGCCAY
RTGGCGTGAY		 SELEX
Yin et al.(2017)
SREBF2_eDBD_HT-SELEX_1 		0.914 0.961
SREBF2
M04220_2.00 		Homo sapiens
ATCACGTGAY
RTCACGTGAT		 SELEX
Yin et al.(2017)
SREBF2_eDBD_HT-SELEX_2 		0.914 0.961
SREBF2
M08059_2.00 		Homo sapiens
RTCACVCCAB
VTGGBGTGAY		 ChIP-seq
Mathelier et al.(2014)
MA0596.1 		0.914 0.961
SREBF2
M08741_2.00 		Homo sapiens
NNYCWSBCCABBB
VVVTGGVSWGRNN		 Misc
Kulakovskiy et al.(2013)
SRBP2_HUMAN.H11MO.0.B 		0.914 0.961
Srebf2
M08752_2.00 		Mus musculus
NNYCWSBCCABBB
VVVTGGVSWGRNN		 Misc
Kulakovskiy et al.(2013)
SRBP2_MOUSE.H11MO.0.B 		0.914 0.961
SREBF2
M09462_2.00 		Homo sapiens
MNRTCACVCCAC
GTGGBGTGAYNK		 Misc
Heinz et al.(2010)
HepG2-Srebp2_GSE31477 		0.914 0.961
SREBF2
M09882_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SREBP2_Q6_01 		0.914 0.961
SREBF2
M09883_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SREBP2_Q6 		0.914 0.961
SREBF2
M04221_2.00 		Homo sapiens
RTCACVCCAY
RTGGBGTGAY		 SELEX
Yin et al.(2017)
SREBF2_eDBD_Methyl-HT-SELEX_1 		0.914 0.961
SREBF2
M04222_2.00 		Homo sapiens
RTCACSTGAY
RTCASGTGAY		 SELEX
Yin et al.(2017)
SREBF2_eDBD_Methyl-HT-SELEX_2 		0.914 0.961
Srebf1
M00754_2.00 		Mus musculus
VWCAYVYSAB
VTSRBRTGWB		 PBM
Weirauch et al.(2013)
pTH0914 		0.862 0.765
Srebf1
M01724_2.00 		Mus musculus
RWCAYVYBD
HVRBRTGWY		 PBM
Weirauch et al.(2014)
pTH5161 		0.862 0.765
Srebf1
M02816_2.00 		Mus musculus
RTCACGTGAY
RTCACGTGAY		 SELEX
Jolma et al.(2013)
Srebf1_1 		0.862 0.765
SREBF1
M04062_2.00 		Homo sapiens
VHCACVCSAY
RTSGBGTGDB		 SELEX
Yin et al.(2017)
SREBF1_eDBD_HT-SELEX_1 		0.862 0.765
SREBF1
M04063_2.00 		Homo sapiens
VHCRCGYGDB
VHCRCGYGDB		 SELEX
Yin et al.(2017)
SREBF1_eDBD_HT-SELEX_2 		0.862 0.765
SREBF1
M08048_2.00 		Homo sapiens
VTCACSCCAY
RTGGSGTGAB		 ChIP-seq
Mathelier et al.(2014)
MA0595.1 		0.862 0.765
SREBF1
M08711_2.00 		Homo sapiens
VTCACVYSAYH
DRTSRBGTGAB		 Misc
Kulakovskiy et al.(2013)
SRBP1_HUMAN.H11MO.0.A 		0.862 0.765
Srebf1
M08749_2.00 		Mus musculus
VTCASSYSABN
NVTSRSSTGAB		 Misc
Kulakovskiy et al.(2013)
SRBP1_MOUSE.H11MO.0.B 		0.862 0.765
SREBF1
M09796_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SREBF1_02 		0.862 0.765
SREBF1
M09797_2.00 		Homo sapiens
NATCACGTGAB
VTCACGTGATN		 Transfac
Matys et al.(2006)
V$SREBP1_01 		0.862 0.765
SREBF1
M09798_2.00 		Homo sapiens
KRTCACCCCAC
GTGGGGTGAYM		 Transfac
Matys et al.(2006)
V$SREBP1_02 		0.862 0.765
SREBF1
M09799_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SREBP1_Q5 		0.862 0.765
SREBF1
M09800_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SREBP1_Q6_01 		0.862 0.765
SREBF1
M09801_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SREBP1_Q6 		0.862 0.765
SREBF1
M04064_2.00 		Homo sapiens
MTCACVCCAY
RTGGBGTGAK		 SELEX
Yin et al.(2017)
SREBF1_eDBD_Methyl-HT-SELEX_1 		0.862 0.765
SREBF1
M04065_2.00 		Homo sapiens
RTCACCTGAY
RTCAGGTGAY		 SELEX
Yin et al.(2017)
SREBF1_eDBD_Methyl-HT-SELEX_2 		0.862 0.765
HLH106
M03626_2.00 		Drosophila melanogaster
RTCACGTGAY
RTCACGTGAY		 SELEX
Nitta et al.(2015)
HLH106_1 		0.838 0.627
HLH106
M03627_2.00 		Drosophila melanogaster
NRTCACGCCAYH
DRTGGCGTGAYN		 SELEX
Nitta et al.(2015)
HLH106_2 		0.838 0.627
For this family, TFs with SR scores > 0.838 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
AAH72922 bHLH 291 341

Links

Other bHLH family TFs
Other Xenopus laevis TFs

143 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ENSAMEG00000005129 Ailuropoda melanoleuca ENSAMEG00000005129 I 0.862
ENSAMEG00000015506 Ailuropoda melanoleuca ENSAMEG00000015506 I 0.914
Alligator_sinensis_CCG007971.1 Alligator sinensis Alligator_sinensis_CCG007971.1 I 0.914
Alligator_sinensis_CCG012315.1 Alligator sinensis Alligator_sinensis_CCG012315.1 I 0.838
ENSAPLG00000003145 Anas platyrhynchos ENSAPLG00000003145 I 0.912
SREBF2 Anolis carolinensis ENSACAG00000004146 I 0.914
Afo_R007963 Aptenodytes forsteri Afo_R007963 I 0.914
ENSAMXG00000008028 Astyanax mexicanus ENSAMXG00000008028 I 0.914
ENSAMXG00000009016 Astyanax mexicanus ENSAMXG00000009016 I 0.862
ENSBTAP00000018956-D1 Bos grunniens ENSBTAP00000018956-D1 I 0.914
SREBF1 Bos taurus ENSBTAG00000007884 I 0.862
SREBF2 Bos taurus ENSBTAG00000014265 I 0.914
ENSCJAG00000002378 Callithrix jacchus ENSCJAG00000002378 I 0.914
SREBF1 Callithrix jacchus ENSCJAG00000008953 I 0.862
Aan_R009070 Calypte anna Aan_R009070 I 0.862
Aan_R013218 Calypte anna Aan_R013218 I 0.914
SREBF2 Canis familiaris ENSCAFG00000001013 I 0.914
SREBF1 Canis familiaris ENSCAFG00000018436 I 0.862
SREBF1 Cavia porcellus ENSCPOG00000002439 I 0.862
SREBF2 Cavia porcellus ENSCPOG00000013199 I 0.914
Cmyd_10007930 Chelonia mydas Cmyd_10007930 I 0.914
Cmyd_10008393 Chelonia mydas Cmyd_10008393 I 0.848
ENSCSAG00000005734 Chlorocebus sabaeus ENSCSAG00000005734 I 0.914
ENSCSAG00000008412 Chlorocebus sabaeus ENSCSAG00000008412 I 0.862
srebf2 Danio rerio ENSDARG00000063438 I 0.914
srebf1 Danio rerio ENSDARG00000067607 I 0.862
SREBF2 Dasypus novemcinctus ENSDNOG00000048031 I 0.914
YQE_07365 Dendroctonus ponderosae YQE_07365 I 0.838
Srebf2 Dipodomys ordii ENSDORG00000000691 I 0.914
Srebf1 Dipodomys ordii ENSDORG00000012333 I 0.862
SREBP Drosophila ananassae FBgn0100584 I 0.838
SREBP Drosophila erecta FBgn0108291 I 0.838
SREBP Drosophila grimshawi FBgn0122129 I 0.838
HLH106 Drosophila melanogaster FBgn0261283 D 0.838
SREBP Drosophila persimilis FBgn0153336 I 0.838
SREBP Drosophila pseudoobscura FBgn0081122 I 0.838
SREBP Drosophila sechellia FBgn0174544 I 0.838
SREBP Drosophila simulans FBgn0186498 I 0.838
SREBP Drosophila virilis FBgn0198580 I 0.838
SREBP Drosophila willistoni FBgn0219495 I 0.838
SREBP Drosophila yakuba FBgn0236960 I 0.838
SREBF2 Echinops telfairi ENSETEG00000000459 I 0.914
SREBF1 Echinops telfairi ENSETEG00000004179 I 0.862
SREBF1 Equus caballus ENSECAG00000019802 I 0.862
SREBF2 Equus caballus ENSECAG00000024608 I 0.914
SREBF2 Erinaceus europaeus ENSEEUG00000003437 I 0.914
SREBF1 Felis catus ENSFCAG00000001983 I 0.862
SREBF2 Felis catus ENSFCAG00000014289 I 0.914
ENSFALG00000011811 Ficedula albicollis ENSFALG00000011811 I 0.914
ENSFALG00000013762 Ficedula albicollis ENSFALG00000013762 I 0.862
ENSGMOG00000006325 Gadus morhua ENSGMOG00000006325 I 0.914
ENSGALG00000011916 Gallus gallus ENSGALG00000011916 I 0.912
SREBF1 Gallus gallus ENSGALG00000027188 I 0.862
srebf2 Gasterosteus aculeatus ENSGACG00000007259 I 0.901
srebf1 Gasterosteus aculeatus ENSGACG00000012064 I 0.862
Gfo_R004756 Geospiza fortis Gfo_R004756 I 0.914
Gfo_R006283 Geospiza fortis Gfo_R006283 I 0.862
SREBF1 Gorilla gorilla ENSGGOG00000002713 I 0.862
SREBF2 Gorilla gorilla ENSGGOG00000012065 I 0.914
HHAL003331-PA Halyomorpha halys HHAL003331-PA I 0.846
SREBF1 Homo sapiens ENSG00000072310 D 0.862
SREBF2 Homo sapiens ENSG00000198911 D 0.914
ENSSTOG00000012916 Ictidomys tridecemlineatus ENSSTOG00000012916 I 0.914
ENSSTOG00000014939 Ictidomys tridecemlineatus ENSSTOG00000014939 I 0.862
ENSLACG00000013149 Latimeria chalumnae ENSLACG00000013149 I 0.862
ENSLOCG00000008766 Lepisosteus oculatus ENSLOCG00000008766 I 0.862
ENSLOCG00000011887 Lepisosteus oculatus ENSLOCG00000011887 I 0.914
LotgiG224211 Lottia gigantea LotgiG224211 I 0.838
SREBF2 Loxodonta africana ENSLAFG00000005791 I 0.914
SREBF1 Loxodonta africana ENSLAFG00000021644 I 0.862
ENSP00000348069 Macaca fascicularis ENSP00000348069 I 0.862
ENSP00000354476 Macaca fascicularis ENSP00000354476 I 0.914
SREBF2 Macaca mulatta ENSMMUG00000003357 I 0.914
SREBF1 Macaca mulatta ENSMMUG00000023375 I 0.862
ENSMEUG00000001306 Macropus eugenii ENSMEUG00000001306 I 0.862
ENSMEUG00000011986 Macropus eugenii ENSMEUG00000011986 I 0.914
SREBF2 Meleagris gallopavo ENSMGAG00000012074 I 0.912
SREBF2 Microcebus murinus ENSMICG00000000913 I 0.914
SREBF1 Microcebus murinus ENSMICG00000012535 I 0.862
SREBF1 Monodelphis domestica ENSMODG00000014074 I 0.862
SREBF2 Monodelphis domestica ENSMODG00000016612 I 0.914
ENSMPUG00000000024 Mustela putorius furo ENSMPUG00000000024 I 0.862
ENSMPUG00000016372 Mustela putorius furo ENSMPUG00000016372 I 0.914
Srebf1 Mus musculus ENSMUSG00000020538 D 0.862
Srebf2 Mus musculus ENSMUSG00000022463 D 0.914
Myotis_brandtii_SREBF1_10023215 Myotis brandtii Myotis_brandtii_SREBF1_10023215 I 0.862
Myotis_brandtii_SREBF2_10014539 Myotis brandtii Myotis_brandtii_SREBF2_10014539 I 0.914
SREBF2 Myotis lucifugus ENSMLUG00000002549 I 0.914
NV10553 Nasonia vitripennis NV10553 I 0.838
ENSNLEG00000013625 Nomascus leucogenys ENSNLEG00000013625 I 0.862
SREBF1 Ochotona princeps ENSOPRG00000015069 I 0.862
Ogr11708 Ophisaurus gracilis Ogr11708 I 0.838
Ogr14454 Ophisaurus gracilis Ogr14454 I 0.914
ENSONIG00000002304 Oreochromis niloticus ENSONIG00000002304 I 0.862
ENSONIG00000008375 Oreochromis niloticus ENSONIG00000008375 I 0.914
SREBF2 Ornithorhynchus anatinus ENSOANG00000002461 I 0.914
SREBF1 Ornithorhynchus anatinus ENSOANG00000012278 I 0.862
SREBF2 Oryctolagus cuniculus ENSOCUG00000003178 I 0.914
srebf1 Oryzias latipes ENSORLG00000009437 I 0.862
srebf2 Oryzias latipes ENSORLG00000014672 I 0.914
SREBF1 Otolemur garnettii ENSOGAG00000002910 I 0.862
SREBF2 Otolemur garnettii ENSOGAG00000014736 I 0.914
ENSOARG00000001504 Ovis aries ENSOARG00000001504 I 0.862
ENSOARG00000018717 Ovis aries ENSOARG00000018717 I 0.914
SREBF2 Pan troglodytes ENSPTRG00000014439 I 0.914
ENSPANG00000008691 Papio anubis ENSPANG00000008691 I 0.914
ENSPANG00000023675 Papio anubis ENSPANG00000023675 I 0.862
ENSPSIG00000014746 Pelodiscus sinensis ENSPSIG00000014746 I 0.914
ENSPMAG00000001400 Petromyzon marinus ENSPMAG00000001400 I 0.860
ENSPFOG00000000475 Poecilia formosa ENSPFOG00000000475 I 0.914
ENSPFOG00000010306 Poecilia formosa ENSPFOG00000010306 I 0.862
Pvit_05020 Pogona vitticeps Pvit_05020 I 0.838
Pvit_18605 Pogona vitticeps Pvit_18605 I 0.914
ENSPPYG00000008037 Pongo abelii ENSPPYG00000008037 I 0.862
ENSPPYG00000011880 Pongo abelii ENSPPYG00000011880 I 0.914
SREBF2 Procavia capensis ENSPCAG00000006497 I 0.914
SREBF1 Procavia capensis ENSPCAG00000014903 I 0.862
SREBF2 Pteropus vampyrus ENSPVAG00000001177 I 0.914
SREBF1 Pteropus vampyrus ENSPVAG00000005765 I 0.862
Srebf1 Rattus norvegicus ENSRNOG00000003463 I 0.862
Srebf2 Rattus norvegicus ENSRNOG00000007400 I 0.914
RPRC014734 Rhodnius prolixus RPRC014734 I 0.846
Sakowv30028178m.g Saccoglossus kowalevskii Sakowv30028178m.g I 0.902
ENSSHAG00000011682 Sarcophilus harrisii ENSSHAG00000011682 I 0.914
ENSSHAG00000018607 Sarcophilus harrisii ENSSHAG00000018607 I 0.862
ENSSARG00000006597 Sorex araneus ENSSARG00000006597 I 0.914
ENSSSCG00000023124 Sus scrofa ENSSSCG00000023124 I 0.862
SREBF2 Sus scrofa ENSSSCG00000026092 I 0.914
SREBF1 Taeniopygia guttata ENSTGUG00000007313 I 0.862
ENSTGUG00000009772 Taeniopygia guttata ENSTGUG00000009772 I 0.914
srebf2 Takifugu rubripes ENSTRUG00000007413 I 0.914
tetur08g03870 Tetranychus urticae tetur08g03870 I 0.838
srebf2 Tetraodon nigroviridis ENSTNIG00000010835 I 0.914
srebf1 Tetraodon nigroviridis ENSTNIG00000011957 I 0.862
TC007163 Tribolium castaneum TC007163 I 0.865
SREBF2 Tupaia belangeri ENSTBEG00000016542 I 0.914
SREBF2 Tursiops truncatus ENSTTRG00000017350 I 0.914
Tal_R010023 Tyto alba Tal_R010023 I 0.914
srebf2 Xenopus tropicalis XB-GENE-1011360 I 0.914
srebf1 Xenopus tropicalis XB-GENE-987572 I 0.862
XP_002944649 Xenopus tropicalis XP_002944649 I 0.862
ENSXMAG00000003080 Xiphophorus maculatus ENSXMAG00000003080 I 0.914
ENSXMAG00000014774 Xiphophorus maculatus ENSXMAG00000014774 I 0.862