Gli3 (Mus musculus)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSMUSG00000021318 T101021_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Gli3
M01022_2.00		 Mus musculus
NGACCACCCNN
NNGGGTGGTCN		 PBM
Peterson et al.(2012)
Gli3		 (Direct) (Direct)
Gli3
M08023_2.00		 Mus musculus
RGVCCACCCAS
STGGGTGGBCY		 ChIP-seq
Chen et al.(2011)
GSE11062_Gli3		 (Direct) (Direct)
Gli3
M09512_2.00		 Mus musculus
RGACCACCCASR
YSTGGGTGGTCY		 Misc
Heinz et al.(2010)
Limb-GLI3_GSE11077		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
GLI3
M04416_2.00 		Homo sapiens
VGACCACCCACVNHG
CDNBGTGGGTGGTCB		 SELEX
Yin et al.(2017)
GLI3_eDBD_HT-SELEX 		0.781 0.983
GLI3
M02642_2.00 		Homo sapiens
GACCACCCANK
MNTGGGTGGTC		 SELEX
Hallikas et al.(2006)
GLI3 		0.781 0.983
GLI3
M08875_2.00 		Homo sapiens
VRACCACCCAV
BTGGGTGGTYB		 Misc
Kulakovskiy et al.(2013)
GLI3_HUMAN.H11MO.0.B 		0.781 0.983
GLI3
M10167_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$GLI3_01 		0.781 0.983
GLI3
M10168_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$GLI3_Q5_01 		0.781 0.983
GLI3
M04417_2.00 		Homo sapiens
CWHBGTGGGTGGTCY
RGACCACCCACVDWG		 SELEX
Yin et al.(2017)
GLI3_eDBD_Methyl-HT-SELEX 		0.781 0.983
Gli2
M01024_2.00 		Mus musculus
NGACCACCYN
NRGGTGGTCN		 PBM
Peterson et al.(2012)
Gli2 		0.761 0.930
GLI2
M02875_2.00 		Homo sapiens
GMCCACMCANVNHB
VDNBNTGKGTGGKC		 SELEX
Jolma et al.(2013)
GLI2_1 		0.761 0.930
GLI2
M02876_2.00 		Homo sapiens
GCGACCACVCWR
YWGBGTGGTCGC		 SELEX
Jolma et al.(2013)
GLI2_2 		0.761 0.930
GLI2
M02732_2.00 		Homo sapiens
GACCACMCAN
NTGKGTGGTC		 SELEX
Jolma et al.(2010)
GLI2_monomer 		0.761 0.930
GLI2
M04402_2.00 		Homo sapiens
VGACCACCCACVDHG
CDHBGTGGGTGGTCB		 SELEX
Yin et al.(2017)
GLI2_eDBD_HT-SELEX 		0.761 0.930
GLI2
M02641_2.00 		Homo sapiens
GACCACCCAHG
CDTGGGTGGTC		 SELEX
Hallikas et al.(2006)
GLI2 		0.761 0.930
GLI2
M10114_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$GLI2_Q3 		0.761 0.930
GLI2
M10115_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$GLI2_Q6 		0.761 0.930
GLI2
M04403_2.00 		Homo sapiens
RGACCACCCACVWWG
CWWBGTGGGTGGTCY		 SELEX
Yin et al.(2017)
GLI2_eDBD_Methyl-HT-SELEX 		0.761 0.930
For this family, TFs with SR scores > 0.755 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M01022_2.00 C2H2 ZF 16 41
M01022_2.00 C2H2 ZF 49 76
M01022_2.00 C2H2 ZF 82 106
M01022_2.00 C2H2 ZF 112 137
M01022_2.00 C2H2 ZF 143 168

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000106137 C2H2 ZF 480 505
ENSMUSP00000106137 C2H2 ZF 513 540
ENSMUSP00000106137 C2H2 ZF 546 570
ENSMUSP00000106137 C2H2 ZF 576 601
ENSMUSP00000106137 C2H2 ZF 607 632
ENSMUSP00000115989 C2H2 ZF 480 505
ENSMUSP00000115989 C2H2 ZF 513 540
ENSMUSP00000115989 C2H2 ZF 546 570
ENSMUSP00000115989 C2H2 ZF 576 596

Links

Other C2H2 ZF family TFs
Other Mus musculus TFs

139 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ENSAMEG00000008405 Ailuropoda melanoleuca ENSAMEG00000008405 I 0.781
ENSAMEG00000008708 Ailuropoda melanoleuca ENSAMEG00000008708 I 0.761
ENSAPLG00000004361 Anas platyrhynchos ENSAPLG00000004361 I 0.781
ENSAPLG00000005128 Anas platyrhynchos ENSAPLG00000005128 I 0.774
ENSAPLG00000015141 Anas platyrhynchos ENSAPLG00000015141 I 0.775
GLI2 Anolis carolinensis ENSACAG00000004133 I 0.773
GLI1 Anolis carolinensis ENSACAG00000006541 I 0.778
GLI3 Anolis carolinensis ENSACAG00000017547 I 0.781
Afo_R006826 Aptenodytes forsteri Afo_R006826 I 0.775
Afo_R007816 Aptenodytes forsteri Afo_R007816 I 0.781
ENSAMXG00000002477 Astyanax mexicanus ENSAMXG00000002477 I 0.776
ENSAMXG00000003125 Astyanax mexicanus ENSAMXG00000003125 I 0.773
ENSAMXG00000006646 Astyanax mexicanus ENSAMXG00000006646 I 0.773
ENSAMXG00000017236 Astyanax mexicanus ENSAMXG00000017236 I 0.776
ENSP00000390436-D1 Bos grunniens ENSP00000390436-D1 I 0.761
GLI3 Bos taurus ENSBTAG00000010671 I 0.781
GLI2 Bos taurus ENSBTAG00000011682 I 0.761
fgenesh2_pg.scaffold_137000068 Branchiostoma floridae fgenesh2_pg.scaffold_137000068 I 0.811
fgenesh2_pg.scaffold_169000072 Branchiostoma floridae fgenesh2_pg.scaffold_169000072 I 0.811
Brh_R008256 Buceros rhinoceros Brh_R008256 I 0.781
Brh_R010932 Buceros rhinoceros Brh_R010932 I 0.775
GLI3 Callithrix jacchus ENSCJAG00000007690 I 0.781
ENSCJAG00000013342 Callithrix jacchus ENSCJAG00000013342 I 0.761
Aan_R003640 Calypte anna Aan_R003640 I 0.775
Aan_R014715 Calypte anna Aan_R014715 I 0.781
GLI3 Canis familiaris ENSCAFG00000003535 I 0.781
GLI2 Canis familiaris ENSCAFG00000004821 I 0.761
GLI3 Cavia porcellus ENSCPOG00000013233 I 0.827
GLI2 Cavia porcellus ENSCPOG00000015189 I 0.761
Cmyd_10007839 Chelonia mydas Cmyd_10007839 I 0.781
Cmyd_10009086 Chelonia mydas Cmyd_10009086 I 0.775
ENSCSAG00000015361 Chlorocebus sabaeus ENSCSAG00000015361 I 0.781
ENSCSAG00000016668 Chlorocebus sabaeus ENSCSAG00000016668 I 0.761
GLI3 Choloepus hoffmanni ENSCHOG00000003774 I 0.781
gli2b Danio rerio ENSDARG00000020884 I 0.773
gli2a Danio rerio ENSDARG00000025641 I 0.815
gli3 Danio rerio ENSDARG00000052131 I 0.779
gli1 Danio rerio ENSDARG00000101244 I 0.766
GLI2 Dasypus novemcinctus ENSDNOG00000008730 I 0.761
GLI3 Dasypus novemcinctus ENSDNOG00000049286 I 0.781
GLI3 Echinops telfairi ENSETEG00000003955 I 0.765
GLI3 Equus caballus ENSECAG00000009281 I 0.781
GLI3 Felis catus ENSFCAG00000011989 I 0.781
GLI2 Felis catus ENSFCAG00000014531 I 0.761
ENSFALG00000005113 Ficedula albicollis ENSFALG00000005113 I 0.781
ENSFALG00000013217 Ficedula albicollis ENSFALG00000013217 I 0.775
ENSGMOG00000007975 Gadus morhua ENSGMOG00000007975 I 0.820
ENSGMOG00000010335 Gadus morhua ENSGMOG00000010335 I 0.817
GLI2 Gallus gallus ENSGALG00000011630 I 0.775
ENSGALG00000012329 Gallus gallus ENSGALG00000012329 I 0.781
ENSGALG00000014639 Gallus gallus ENSGALG00000014639 I 0.764
gli2b Gasterosteus aculeatus ENSGACG00000001547 I 0.809
gli1 Gasterosteus aculeatus ENSGACG00000006458 I 0.820
Gfo_R001212 Geospiza fortis Gfo_R001212 I 0.775
Gfo_R007869 Geospiza fortis Gfo_R007869 I 0.781
Gfo_R013682 Geospiza fortis Gfo_R013682 I 0.774
GLI3 Gorilla gorilla ENSGGOG00000002026 I 0.781
GLI2 Gorilla gorilla ENSGGOG00000009653 I 0.757
GLI2 Homo sapiens ENSG00000074047 D 0.761
GLI3 Homo sapiens ENSG00000106571 D 0.781
ENSSTOG00000004582 Ictidomys tridecemlineatus ENSSTOG00000004582 I 0.761
ENSSTOG00000020844 Ictidomys tridecemlineatus ENSSTOG00000020844 I 0.827
ENSLACG00000017364 Latimeria chalumnae ENSLACG00000017364 I 0.781
ENSLOCG00000002028 Lepisosteus oculatus ENSLOCG00000002028 I 0.819
ENSLOCG00000005938 Lepisosteus oculatus ENSLOCG00000005938 I 0.776
ENSLOCG00000011983 Lepisosteus oculatus ENSLOCG00000011983 I 0.771
GLI3 Loxodonta africana ENSLAFG00000008944 I 0.781
ENSMMUP00000002494 Macaca fascicularis ENSMMUP00000002494 I 0.761
ENSP00000379258 Macaca fascicularis ENSP00000379258 I 0.781
GLI2 Macaca mulatta ENSMMUG00000001868 I 0.761
GLI3 Macaca mulatta ENSMMUG00000013614 I 0.781
ENSMEUG00000013134 Macropus eugenii ENSMEUG00000013134 I 0.781
ENSMGAG00000003540 Meleagris gallopavo ENSMGAG00000003540 I 0.764
GLI2 Meleagris gallopavo ENSMGAG00000011872 I 0.775
GLI3 Meleagris gallopavo ENSMGAG00000012277 I 0.781
GLI3 Microcebus murinus ENSMICG00000010785 I 0.765
GLI2 Monodelphis domestica ENSMODG00000000245 I 0.766
GLI3 Monodelphis domestica ENSMODG00000002714 I 0.781
ENSMPUG00000000986 Mustela putorius furo ENSMPUG00000000986 I 0.761
ENSMPUG00000018143 Mustela putorius furo ENSMPUG00000018143 I 0.781
Gli2 Mus musculus ENSMUSG00000048402 D 0.761
Myotis_brandtii_Gli2_10019076 Myotis brandtii Myotis_brandtii_Gli2_10019076 I 0.761
GLI3 Myotis lucifugus ENSMLUG00000015711 I 0.781
ENSNLEG00000000944 Nomascus leucogenys ENSNLEG00000000944 I 0.761
ENSNLEG00000003160 Nomascus leucogenys ENSNLEG00000003160 I 0.781
GLI3 Ochotona princeps ENSOPRG00000011225 I 0.781
Ogr02489 Ophisaurus gracilis Ogr02489 I 0.773
ENSONIG00000003608 Oreochromis niloticus ENSONIG00000003608 I 0.821
ENSONIG00000004472 Oreochromis niloticus ENSONIG00000004472 I 0.819
ENSONIG00000005084 Oreochromis niloticus ENSONIG00000005084 I 0.818
GLI3 Ornithorhynchus anatinus ENSOANG00000010699 I 0.781
GLI2 Oryctolagus cuniculus ENSOCUG00000000638 I 0.761
GLI3 Oryctolagus cuniculus ENSOCUG00000006563 I 0.781
gli1 Oryzias latipes ENSORLG00000005455 I 0.818
GLI3 Otolemur garnettii ENSOGAG00000012651 I 0.781
GLI2 Otolemur garnettii ENSOGAG00000032438 I 0.766
ENSOARG00000013052 Ovis aries ENSOARG00000013052 I 0.761
ENSOARG00000017420 Ovis aries ENSOARG00000017420 I 0.781
GLI2 Pan troglodytes ENSPTRG00000012413 I 0.761
GLI3 Pan troglodytes ENSPTRG00000019117 I 0.781
ENSPANG00000014545 Papio anubis ENSPANG00000014545 I 0.781
ENSPANG00000024168 Papio anubis ENSPANG00000024168 I 0.761
ENSPSIG00000008752 Pelodiscus sinensis ENSPSIG00000008752 I 0.775
ENSPSIG00000017804 Pelodiscus sinensis ENSPSIG00000017804 I 0.781
ENSPFOG00000005116 Poecilia formosa ENSPFOG00000005116 I 0.775
ENSPFOG00000006269 Poecilia formosa ENSPFOG00000006269 I 0.818
ENSPFOG00000014778 Poecilia formosa ENSPFOG00000014778 I 0.822
Pvit_05813 Pogona vitticeps Pvit_05813 I 0.778
Pvit_06470 Pogona vitticeps Pvit_06470 I 0.773
Pvit_19093 Pogona vitticeps Pvit_19093 I 0.781
ENSPPYG00000012778 Pongo abelii ENSPPYG00000012778 I 0.761
ENSPPYG00000017613 Pongo abelii ENSPPYG00000017613 I 0.781
GLI2 Procavia capensis ENSPCAG00000001704 I 0.758
GLI3 Procavia capensis ENSPCAG00000015092 I 0.781
GLI3 Pteropus vampyrus ENSPVAG00000015920 I 0.781
Gli2 Rattus norvegicus ENSRNOG00000007261 I 0.761
Gli3 Rattus norvegicus ENSRNOG00000014395 I 0.827
ENSSHAG00000004233 Sarcophilus harrisii ENSSHAG00000004233 I 0.766
ENSSHAG00000009727 Sarcophilus harrisii ENSSHAG00000009727 I 0.781
GLI2 Sus scrofa ENSSSCG00000015733 I 0.761
GLI2 Taeniopygia guttata ENSTGUG00000004599 I 0.775
gli2b Takifugu rubripes ENSTRUG00000001954 I 0.809
gli2b Takifugu rubripes ENSTRUG00000010444 I 0.773
gli1 Takifugu rubripes ENSTRUG00000014998 I 0.820
ENSTSYG00000009406 Tarsius syrichta ENSTSYG00000009406 I 0.781
gli1 Tetraodon nigroviridis ENSTNIG00000007058 I 0.822
gli2b Tetraodon nigroviridis ENSTNIG00000010251 I 0.762
gli2b Tetraodon nigroviridis ENSTNIG00000017828 I 0.763
GLI3 Tupaia belangeri ENSTBEG00000006673 I 0.781
GLI3 Tursiops truncatus ENSTTRG00000003628 I 0.781
Tal_R006208 Tyto alba Tal_R006208 I 0.775
Tal_R009020 Tyto alba Tal_R009020 I 0.774
gli2.L Xenopus laevis XB-GENE-17342592 I 0.815
gli2.S Xenopus laevis XB-GENE-6251939 I 0.815
gli3.L Xenopus laevis XB-GENE-865509 I 0.781
XP_002933449 Xenopus tropicalis XP_002933449 I 0.781
XP_002933450 Xenopus tropicalis XP_002933450 I 0.781
ENSXMAG00000006443 Xiphophorus maculatus ENSXMAG00000006443 I 0.775
ENSXMAG00000017965 Xiphophorus maculatus ENSXMAG00000017965 I 0.818