HMBOX1 (Homo sapiens)
Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox) IPR001356 ENSG00000147421 T209858_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
HMBOX1
M03167_2.00		 Homo sapiens
BKTAACTARB
VYTAGTTAMV		 SELEX
Jolma et al.(2013)
HMBOX1_1		 (Direct) (Direct)
HMBOX1
M05180_2.00		 Homo sapiens
BTAACYAGB
VCTRGTTAV		 SELEX
Yin et al.(2017)
HMBOX1_eDBD_HT-SELEX		 (Direct) (Direct)
HMBOX1
M05181_2.00		 Homo sapiens
NTAACTAGB
VCTAGTTAN		 SELEX
Yin et al.(2017)
HMBOX1_eDBD_Methyl-HT-SELEX		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Hmbox1
M00419_2.00 		Mus musculus
NNNGWNNN
NNNWCNNN		 PBM
Berger et al.(2008)
Hmbox1_2674 		0.867 1.000
Hnf1b
M00408_2.00 		Mus musculus
NNHWCNNN
NNNGWDNN		 PBM
Berger et al.(2008)
Tcf2_0913 		0.638 0.368
Hnf1a
M00171_2.00 		Mus musculus
HTAAYYNN
NNRRTTAD		 PBM
Badis et al.(2009)
Tcf1_2666 		0.638 0.368
Hnf1a
M00444_2.00 		Mus musculus
HTAAYYNNN
NNNRRTTAD		 PBM
Berger et al.(2008)
Tcf1_2666 		0.638 0.368
HNF1A
M03150_2.00 		Homo sapiens
NGTTAATNATTAAYN
NRTTAATNATTAACN		 SELEX
Jolma et al.(2013)
HNF1A_1 		0.638 0.368
HNF1B
M03245_2.00 		Homo sapiens
GTTAATNATTAAY
RTTAATNATTAAC		 SELEX
Jolma et al.(2013)
HNF1B_1 		0.638 0.368
HNF1B
M03246_2.00 		Homo sapiens
NGTTAATNATTAAYN
NRTTAATNATTAACN		 SELEX
Jolma et al.(2013)
HNF1B_2 		0.638 0.368
HNF1A
M09144_2.00 		Homo sapiens
DGTTAATKATTAACH
DGTTAATMATTAACH		 Misc
Kulakovskiy et al.(2013)
HNF1A_HUMAN.H11MO.0.C 		0.638 0.368
HNF1B
M09168_2.00 		Homo sapiens
DGTTAATRATTAACH
DGTTAATYATTAACH		 Misc
Kulakovskiy et al.(2013)
HNF1B_HUMAN.H11MO.0.A 		0.638 0.368
Hnf1a
M09191_2.00 		Mus musculus
RGTTAATNWTTDMHN
NDKHAAWNATTAACY		 Misc
Kulakovskiy et al.(2013)
HNF1A_MOUSE.H11MO.0.A 		0.638 0.368
Hnf1b
M09179_2.00 		Mus musculus
DGTTAATRATTAACH
DGTTAATYATTAACH		 Misc
Kulakovskiy et al.(2013)
HNF1B_MOUSE.H11MO.0.A 		0.638 0.368
HNF1A
M10690_2.00 		Homo sapiens
RGTTAATDWTTRMHV
BDKYAAWHATTAACY		 Transfac
Matys et al.(2006)
V$HNF1_01 		0.638 0.368
HNF1A
M10691_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$HNF1A_Q4 		0.638 0.368
HNF1A
M10692_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$HNF1A_Q5 		0.638 0.368
HNF1B
M10758_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$HNF1B_Q6_01 		0.638 0.368
HNF1B
M10759_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$HNF1B_Q6 		0.638 0.368
HNF1A
M10693_2.00 		Homo sapiens
DGBTAATBAWTHAMYWM
KWRKTDAWTVATTAVCH		 Transfac
Matys et al.(2006)
V$HNF1_C 		0.638 0.368
HNF1B
M10760_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$LFA1_Q6 		0.638 0.368
For this family, TFs with SR scores > 0.599 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000287701 Homeodomain 268 339
ENSP00000380516 Homeodomain 268 339
ENSP00000430059 Homeodomain 268 339
ENSP00000430110 Homeodomain 268 339
ENSP00000452827 Homeodomain 268 339
ENSP00000453185 Homeodomain 268 310
ENSP00000453211 Homeodomain 268 339
ENSP00000475196 Homeodomain 268 339

Links

Other Homeodomain family TFs
Other Homo sapiens TFs

237 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ENSAMEG00000013375 Ailuropoda melanoleuca ENSAMEG00000013375 I
ENSP00000381304-D19 Bos grunniens ENSP00000381304-D19 I
ZNF26 Callithrix jacchus ENSCJAG00000013090 I
ENSCSAG00000001819 Chlorocebus sabaeus ENSCSAG00000001819 I
ZNF26 Dasypus novemcinctus ENSDNOG00000039327 I
ZNF26 Felis catus ENSFCAG00000002509 I
ZNF26 Gorilla gorilla ENSGGOG00000004068 I
ZNF26 Homo sapiens ENSG00000198393 D
ENSSTOG00000008431 Ictidomys tridecemlineatus ENSSTOG00000008431 I
ENSP00000333725 Macaca fascicularis ENSP00000333725 I
ZNF26 Macaca mulatta ENSMMUG00000013868 I
ENSMPUG00000002709 Mustela putorius furo ENSMPUG00000002709 I
Myotis_brandtii_ZNF26_10005226 Myotis brandtii Myotis_brandtii_ZNF26_10005226 I
ENSNLEG00000012466 Nomascus leucogenys ENSNLEG00000012466 I
ZNF26 Oryctolagus cuniculus ENSOCUG00000029684 I
ZNF26 Otolemur garnettii ENSOGAG00000024271 I
ENSOARG00000008447 Ovis aries ENSOARG00000008447 I
ZNF26 Pan troglodytes ENSPTRG00000023082 I
ENSPANG00000011322 Papio anubis ENSPANG00000011322 I
ENSPPYG00000005151 Pongo abelii ENSPPYG00000005151 I
ZNF26 Procavia capensis ENSPCAG00000014220 I
ZNF26 Pteropus vampyrus ENSPVAG00000002106 I
ZNF26 Sorex araneus ENSSARG00000013092 I
ZNF26 Sus scrofa ENSSSCG00000009730 I
ENSTSYG00000013291 Tarsius syrichta ENSTSYG00000013291 I
ZNF26 Tupaia belangeri ENSTBEG00000010158 I
ZNF26 Tursiops truncatus ENSTTRG00000010664 I