Irx6 (Mus musculus)
Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox) IPR001356 ENSMUSG00000031738 T212468_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Irx6
M00456_2.00		 Mus musculus
NNDAHWN
NWDTHNN		 PBM
Berger et al.(2008)
Irx6_2623		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
ara
M06518_2.00 		Drosophila melanogaster
WWACA
TGTWW		 B1H
Mathelier et al.(2014)
MA0210.1 		0.832 0.930
ara
M06313_2.00 		Drosophila melanogaster
TGTWWWNN
NNWWWACA		 B1H
Zhu et al.(2011)
Ara_Cell_FBgn0015904 		0.832 0.930
ara
M06314_2.00 		Drosophila melanogaster
DWWACA
TGTWWH		 B1H
Zhu et al.(2011)
Ara_SOLEXA_FBgn0015904 		0.832 0.930
caup
M06519_2.00 		Drosophila melanogaster
WAACA
TGTTW		 B1H
Mathelier et al.(2014)
MA0217.1 		0.824 0.895
caup
M06315_2.00 		Drosophila melanogaster
HWDWAACA
TGTTWHWD		 B1H
Zhu et al.(2011)
Caup_Cell_FBgn0015919 		0.824 0.895
caup
M06316_2.00 		Drosophila melanogaster
NDDACA
TGTHHN		 B1H
Zhu et al.(2011)
Caup_SOLEXA_FBgn0015919 		0.824 0.895
Irx4
M00416_2.00 		Mus musculus
NNNDAMAH
DTKTHNNN		 PBM
Berger et al.(2008)
Irx4_2242 		0.790 0.912
Irx2
M00386_2.00 		Mus musculus
NNDACAHNN
NNDTGTHNN		 PBM
Berger et al.(2008)
Irx2_0900 		0.780 0.860
Irx5
M00455_2.00 		Mus musculus
NNNDACAHN
NDTGTHNNN		 PBM
Berger et al.(2008)
Irx5_2385 		0.780 0.860
IRX2
M03212_2.00 		Homo sapiens
NDACAYRACAHN
NDTGTYRTGTHN		 SELEX
Jolma et al.(2013)
IRX2_1 		0.780 0.860
IRX5
M03222_2.00 		Homo sapiens
NDACAYRACAHN
NDTGTYRTGTHN		 SELEX
Jolma et al.(2013)
IRX5_1 		0.780 0.860
IRX5
M05315_2.00 		Homo sapiens
NBDTGTHNDACAYVN
NBRTGTHNDACAHVN		 SELEX
Yin et al.(2017)
IRX5_eDBD_HT-SELEX 		0.780 0.860
IRX5
M05316_2.00 		Homo sapiens
WYRYGHHNHAYRYRY
RYRYRTDNDDCRYRW		 SELEX
Yin et al.(2017)
IRX5_eDBD_Methyl-HT-SELEX 		0.780 0.860
For this family, TFs with SR scores > 0.599 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00456_2.00 Homeodomain 17 76

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000034185 Homeodomain 144 203
ENSMUSP00000127446 Homeodomain 144 203

Links

Other Homeodomain family TFs
Other Mus musculus TFs

390 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
LPERR07G02310 Leersia perrieri LPERR07G02310 N
OBART07G02450 Oryza barthii OBART07G02450 N
OB07G12010 Oryza brachyantha OB07G12010 N
ORGLA07G0021600 Oryza glaberrima ORGLA07G0021600 N
OGLUM07G14260 Oryza glumaepatula OGLUM07G14260 N
BGIOSGA024846 Oryza indica BGIOSGA024846 N
OLONG_009970 Oryza longistaminata OLONG_009970 N
OMERI01G11970 Oryza meridionalis OMERI01G11970 N
ONIVA04G19340 Oryza nivara ONIVA04G19340 N
OPUNC07G02500 Oryza punctata OPUNC07G02500 N
Pavir.Ba03827 Panicum virgatum Pavir.Ba03827 N
Pavir.Bb00243 Panicum virgatum Pavir.Bb00243 N
Si028919m.g Setaria italica Si028919m.g N
GRMZM2G051793 Zea mays GRMZM2G051793 N