ascl1 (Xenopus tropicalis)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00010 (HLH) IPR001092 XB-GENE-1032967 T051770_2.00 Misc (2018-Jan-19)

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
ASCL1
M04135_2.00 		Homo sapiens
NRCASSTGYN
NRCASSTGYN		 SELEX
Yin et al.(2017)
ASCL1_eDBD_HT-SELEX 		0.914 1.000
ASCL1
M08055_2.00 		Homo sapiens
NNRGCAGCTGSNN
NNSCAGCTGCYNN		 ChIP-seq
Mathelier et al.(2014)
MA1100.1 		0.914 1.000
ASCL1
M08730_2.00 		Homo sapiens
NNVCASCTGCYBYN
NRVRGCAGSTGBNN		 Misc
Kulakovskiy et al.(2013)
ASCL1_HUMAN.H11MO.0.A 		0.914 1.000
Ascl1
M08748_2.00 		Mus musculus
BHSCASCTGCYBBN
NVVRGCAGSTGSDV		 Misc
Kulakovskiy et al.(2013)
ASCL1_MOUSE.H11MO.0.A 		0.914 1.000
Ascl1
M09464_2.00 		Mus musculus
NVCABCTGBBNN
NNVVCAGVTGBN		 Misc
Heinz et al.(2010)
NeuralTubes-Ascl1_GSE55840 		0.914 1.000
ASCL1
M09855_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$MASH1_Q6_01 		0.914 1.000
ASCL1
M09856_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$MASH1_Q6_02 		0.914 1.000
ASCL1
M09857_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$MASH1_Q6 		0.914 1.000
ASCL1
M04136_2.00 		Homo sapiens
NRCAGCTGYN
NRCAGCTGYN		 SELEX
Yin et al.(2017)
ASCL1_eDBD_Methyl-HT-SELEX 		0.914 1.000
Ascl2
M00117_2.00 		Mus musculus
NVCABVTGBN
NVCABVTGBN		 PBM
Badis et al.(2009)
Ascl2_2654 		0.871 0.880
Ascl2
M02814_2.00 		Mus musculus
RRCAGCTGYY
RRCAGCTGYY		 SELEX
Jolma et al.(2013)
Ascl2_1 		0.871 0.880
Ascl2
M08744_2.00 		Mus musculus
RGCAGSTGB
VCASCTGCY		 Misc
Kulakovskiy et al.(2013)
ASCL2_MOUSE.H11MO.0.C 		0.871 0.880
ASCL2
M04207_2.00 		Homo sapiens
NRCAGCTGYN
NRCAGCTGYN		 SELEX
Yin et al.(2017)
ASCL2_eDBD_HT-SELEX 		0.871 0.860
ASCL2
M04209_2.00 		Homo sapiens
VCACRACGCD
HGCGTYGTGB		 SELEX
Yin et al.(2017)
ASCL2_FL_HT-SELEX_1 		0.871 0.860
ASCL2
M04210_2.00 		Homo sapiens
NRCAGCTGYN
NRCAGCTGYN		 SELEX
Yin et al.(2017)
ASCL2_FL_HT-SELEX_2 		0.871 0.860
ASCL2
M04208_2.00 		Homo sapiens
NRCAGCTGYN
NRCAGCTGYN		 SELEX
Yin et al.(2017)
ASCL2_eDBD_Methyl-HT-SELEX 		0.871 0.860
ASCL2
M04211_2.00 		Homo sapiens
VRCAGCTGYB
VRCAGCTGYB		 SELEX
Yin et al.(2017)
ASCL2_FL_Methyl-HT-SELEX 		0.871 0.860
For this family, TFs with SR scores > 0.838 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
XP_002944648 bHLH 32 82

Links

Other bHLH family TFs
Other Xenopus tropicalis TFs

87 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ENSAMEG00000006449 Ailuropoda melanoleuca ENSAMEG00000006449 I 0.914
ASCL1 Bos taurus ENSBTAG00000016227 I 0.914
ASCL1 Canis familiaris ENSCAFG00000007324 I 0.914
ASCL1 Callithrix jacchus ENSCJAG00000014345 I 0.914
ASCL1 Cavia porcellus ENSCPOG00000020666 I 0.914
ENSCSAG00000018938 Chlorocebus sabaeus ENSCSAG00000018938 I 0.914
ASCL1 Dasypus novemcinctus ENSDNOG00000001616 I 0.914
ASCL1 Felis catus ENSFCAG00000008250 I 0.914
ASCL1 Homo sapiens ENSG00000139352 D 0.914
ASCL1 Gorilla gorilla ENSGGOG00000005479 I 0.914
ENSMEUG00000010370 Macropus eugenii ENSMEUG00000010370 I 0.914
ASCL1 Macaca mulatta ENSMMUG00000005747 I 0.914
ASCL1 Monodelphis domestica ENSMODG00000002347 I 0.914
Ascl1 Mus musculus ENSMUSG00000020052 D 0.914
ENSNLEG00000006410 Nomascus leucogenys ENSNLEG00000006410 I 0.914
ASCL1 Ornithorhynchus anatinus ENSOANG00000013973 I 0.914
ENSOARG00000015879 Ovis aries ENSOARG00000015879 I 0.914
ASCL1 Oryctolagus cuniculus ENSOCUG00000006992 I 0.914
ASCL1 Otolemur garnettii ENSOGAG00000030324 I 0.914
ENSPPYG00000004884 Pongo abelii ENSPPYG00000004884 I 0.914
ASCL1 Pteropus vampyrus ENSPVAG00000011272 I 0.914
Ascl1 Rattus norvegicus ENSRNOG00000004294 I 0.914
ENSSHAG00000011936 Sarcophilus harrisii ENSSHAG00000011936 I 0.914
ENSSTOG00000028420 Ictidomys tridecemlineatus ENSSTOG00000028420 I 0.914
ASCL1 Tursiops truncatus ENSTTRG00000016243 I 0.914
ASCL1 Vicugna pacos ENSVPAG00000002018 I 0.914
ENSBTAP00000021592-D1 Bos grunniens ENSBTAP00000021592-D1 I 0.914
ENSP00000266744 Macaca fascicularis ENSP00000266744 I 0.914
Ogr07565 Ophisaurus gracilis Ogr07565 I 0.914
Pvit_15764 Pogona vitticeps Pvit_15764 I 0.914
ascl1.L Xenopus laevis XB-GENE-1032969 I 0.914
ascl1.S Xenopus laevis XB-GENE-17340658 I 0.914
ascl1a Danio rerio ENSDARG00000038386 I 0.894
ascl1a Gasterosteus aculeatus ENSGACG00000020048 I 0.894
ENSGMOG00000002268 Gadus morhua ENSGMOG00000002268 I 0.894
ENSLACG00000010712 Latimeria chalumnae ENSLACG00000010712 I 0.894
ENSONIG00000021219 Oreochromis niloticus ENSONIG00000021219 I 0.894
ascl1a Oryzias latipes ENSORLG00000016504 I 0.894
ENSPFOG00000018073 Poecilia formosa ENSPFOG00000018073 I 0.894
ascl1a Takifugu rubripes ENSTRUG00000012801 I 0.894
ENSXMAG00000019614 Xiphophorus maculatus ENSXMAG00000019614 I 0.894
ENSLACG00000001911 Latimeria chalumnae ENSLACG00000001911 I 0.886
SMAR011494 Strigamia maritima SMAR011494 I 0.886
ENSAMEG00000002164 Ailuropoda melanoleuca ENSAMEG00000002164 I 0.871
ASCL2 Bos taurus ENSBTAG00000026769 I 0.871
ASCL2 Canis familiaris ENSCAFG00000010103 I 0.871
ASCL2 Callithrix jacchus ENSCJAG00000011549 I 0.871
ENSCPOG00000023523 Cavia porcellus ENSCPOG00000023523 I 0.871
ENSCSAG00000018956 Chlorocebus sabaeus ENSCSAG00000018956 I 0.871
ASCL2 Felis catus ENSFCAG00000018914 I 0.871
ASCL2 Homo sapiens ENSG00000183734 D 0.871
ASCL2 Gorilla gorilla ENSGGOG00000007421 I 0.871
ASCL2 Loxodonta africana ENSLAFG00000020947 I 0.871
ASCL2 Macaca mulatta ENSMMUG00000001322 I 0.871
ENSMPUG00000019849 Mustela putorius furo ENSMPUG00000019849 I 0.871
Ascl2 Mus musculus ENSMUSG00000009248 D 0.871
ENSNLEG00000002663 Nomascus leucogenys ENSNLEG00000002663 I 0.871
ASCL2 Otolemur garnettii ENSOGAG00000034847 I 0.871
ASCL2 Ochotona princeps ENSOPRG00000019165 I 0.871
ENSPANG00000019205 Papio anubis ENSPANG00000019205 I 0.871
ASCL2 Procavia capensis ENSPCAG00000000676 I 0.871
ENSPPYG00000002926 Pongo abelii ENSPPYG00000002926 I 0.871
ASCL2 Pan troglodytes ENSPTRG00000003174 I 0.871
ASCL2 Pteropus vampyrus ENSPVAG00000002964 I 0.871
Ascl2 Rattus norvegicus ENSRNOG00000020434 I 0.871
ENSSTOG00000028167 Ictidomys tridecemlineatus ENSSTOG00000028167 I 0.871
ENSAMXG00000014210 Astyanax mexicanus ENSAMXG00000014210 I 0.864
SPU_028148 Strongylocentrotus purpuratus SPU_028148 I 0.864
Sakowv30008499m.g Saccoglossus kowalevskii Sakowv30008499m.g I 0.864
ENSFALG00000014466 Ficedula albicollis ENSFALG00000014466 I 0.860
ASCL2 Taeniopygia guttata ENSTGUG00000009283 I 0.860
ENSAMXG00000024858 Astyanax mexicanus ENSAMXG00000024858 I 0.859
ascl1b Danio rerio ENSDARG00000101628 I 0.859
ascl1b Gasterosteus aculeatus ENSGACG00000011375 I 0.859
ENSGMOG00000009589 Gadus morhua ENSGMOG00000009589 I 0.859
ENSLOCG00000017318 Lepisosteus oculatus ENSLOCG00000017318 I 0.859
ENSONIG00000020440 Oreochromis niloticus ENSONIG00000020440 I 0.859
ascl1b Oryzias latipes ENSORLG00000012117 I 0.859
ENSPFOG00000020633 Poecilia formosa ENSPFOG00000020633 I 0.859
ascl1b Tetraodon nigroviridis ENSTNIG00000011380 I 0.859
ascl1b Takifugu rubripes ENSTRUG00000011651 I 0.859
ENSXMAG00000019890 Xiphophorus maculatus ENSXMAG00000019890 I 0.859
ENSAMXG00000025568 Astyanax mexicanus ENSAMXG00000025568 I 0.849
ENSGALG00000023607 Gallus gallus ENSGALG00000023607 I 0.847
e_gw.302.11.1 Branchiostoma floridae e_gw.302.11.1 I 0.842
e_gw.59.47.1 Branchiostoma floridae e_gw.59.47.1 I 0.842
ENSAPLG00000001445 Anas platyrhynchos ENSAPLG00000001445 I 0.666