TCF4 (Choloepus hoffmanni)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00010 (HLH) IPR001092 ENSCHOG00000000331 T033224_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Tcf4
M01750_2.00 		Mus musculus
VCAGVTGBN
NVCABCTGB		 PBM
Weirauch et al.(2014)
pTH5101 		0.914 1.000
TCF4
M02807_2.00 		Homo sapiens
HRCACCTGBN
NVCAGGTGYD		 SELEX
Jolma et al.(2013)
TCF4_1 		0.914 1.000
TCF4
M02808_2.00 		Homo sapiens
NVCACCTBBN
NVVAGGTGBN		 SELEX
Jolma et al.(2013)
TCF4_2 		0.914 1.000
TCF4
M02728_2.00 		Homo sapiens
RCACCTG
CAGGTGY		 SELEX
Jolma et al.(2010)
TCF4_dimer 		0.914 1.000
TCF4
M04214_2.00 		Homo sapiens
VCACCTGB
VCAGGTGB		 SELEX
Yin et al.(2017)
TCF4_eDBD_HT-SELEX 		0.914 1.000
Tcf4
M08775_2.00 		Mus musculus
HRCACCTGB
VCAGGTGYD		 Misc
Kulakovskiy et al.(2013)
ITF2_MOUSE.H11MO.0.B 		0.914 1.000
TCF4
M09461_2.00 		Homo sapiens
ASWTCAAAGRVN
NBYCTTTGAWST		 Misc
Heinz et al.(2010)
Hct116-Tcf4_SRA012054 		0.914 1.000
TCF4
M04215_2.00 		Homo sapiens
VCACCTGN
NCAGGTGB		 SELEX
Yin et al.(2017)
TCF4_eDBD_Methyl-HT-SELEX 		0.914 1.000
Tcf12
M01740_2.00 		Mus musculus
NVCAYCTGB
VCAGRTGBN		 PBM
Weirauch et al.(2014)
pTH5071 		0.912 0.962
TCF12
M04137_2.00 		Homo sapiens
VCACSTGB
VCASGTGB		 SELEX
Yin et al.(2017)
TCF12_eDBD_HT-SELEX 		0.912 0.962
Tcf12
M08062_2.00 		Mus musculus
RRCAGCTGNNN
NNNCAGCTGYY		 ChIP-seq
Mathelier et al.(2014)
MA0521.1 		0.912 0.962
TCF12
M07805_2.00 		Homo sapiens
NVDSCAGSTGB
VCASCTGSHBN		 ChIP-seq
Gerstein et al.(2012)
GM12878_TCF12_HudsonAlpha 		0.912 0.962
TCF12
M07806_2.00 		Homo sapiens
VCASCTGB
VCAGSTGB		 ChIP-seq
Gerstein et al.(2012)
H1-hESC_TCF12_HudsonAlpha 		0.912 0.962
TCF12
M08731_2.00 		Homo sapiens
CMCASCTGSH
DSCAGSTGKG		 Misc
Kulakovskiy et al.(2013)
HTF4_HUMAN.H11MO.0.A 		0.912 0.962
Tcf12
M08762_2.00 		Mus musculus
VMCASCTGSH
DSCAGSTGKB		 Misc
Kulakovskiy et al.(2013)
HTF4_MOUSE.H11MO.0.A 		0.912 0.962
TCF12
M09458_2.00 		Homo sapiens
NNVCAGCTGB
VCAGCTGBNN		 Misc
Heinz et al.(2010)
GM12878-Tcf12_GSE32465 		0.912 0.962
TCF12
M09858_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$HEB_Q6 		0.912 0.962
TCF12
M09859_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$HTF4_Q2 		0.912 0.962
TCF12
M09860_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TCF12_01 		0.912 0.962
TCF12
M09861_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TCF12_03 		0.912 0.962
TCF12
M09862_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TCF12_05 		0.912 0.962
TCF12
M04138_2.00 		Homo sapiens
NCAYCTGN
NCAGRTGN		 SELEX
Yin et al.(2017)
TCF12_eDBD_Methyl-HT-SELEX 		0.912 0.962
Tcf3
M00753_2.00 		Mus musculus
VCACCTGBN
NVCAGGTGB		 PBM
Weirauch et al.(2013)
pTH3866 		0.912 0.885
Tcf3
M01723_2.00 		Mus musculus
NNVCACSTGB
VCASGTGBNN		 PBM
Weirauch et al.(2014)
pTH4580 		0.912 0.885
Tcf3
M00118_2.00 		Mus musculus
VCAYCTGB
VCAGRTGB		 PBM
Badis et al.(2009)
Tcfe2a_3865 		0.912 0.885
Tcf3
M09465_2.00 		Mus musculus
ABWTCAAAGS
SCTTTGAWVT		 Misc
Heinz et al.(2010)
mES-Tcf3_GSE11724 		0.884 0.923
Tcf3
M09466_2.00 		Mus musculus
VCAGCTGBNN
NNVCAGCTGB		 Misc
Heinz et al.(2010)
proBcell-E2A_GSE21978 		0.884 0.923
Tcf3
M09886_2.00 		Mus musculus Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E47_05 		0.884 0.923
TCF3
M02775_2.00 		Homo sapiens
NVCACCTGBN
NVCAGGTGBN		 SELEX
Jolma et al.(2013)
TCF3_1 		0.884 0.885
TCF3
M08710_2.00 		Homo sapiens
VVCASCTGCHN
NDGCAGSTGBB		 Misc
Kulakovskiy et al.(2013)
TFE2_HUMAN.H11MO.0.A 		0.884 0.885
TCF3
M09791_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E12_Q6 		0.884 0.885
TCF3
M09792_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E2A_Q6_01 		0.884 0.885
TCF3
M09793_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E2A_Q6_02 		0.884 0.885
TCF3
M09794_2.00 		Homo sapiens
VVVVMCACCTGCNBB
VVNGCAGGTGKBBBB		 Transfac
Matys et al.(2006)
V$E47_01 		0.884 0.885
TCF3
M09795_2.00 		Homo sapiens
NNKWRCACCTGYDNNN
NNNHRCAGGTGYWMNN		 Transfac
Matys et al.(2006)
V$E47_02 		0.884 0.885
For this family, TFs with SR scores > 0.838 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSCHOP00000000292 bHLH 575 628

Links

Other bHLH family TFs
Other Choloepus hoffmanni TFs

212 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
AAEL001347 Aedes aegypti AAEL001347 N
AATE011073 Anopheles atroparvus AATE011073 N
AATE011230 Anopheles atroparvus AATE011230 N
ACEP15165 Atta cephalotes ACEP15165 N
ACHR000032 Anopheles christyi ACHR000032 N
ACHR010096 Anopheles christyi ACHR010096 N
ACOM033895 Anopheles coluzzii ACOM033895 N
ACUA000836 Anopheles culicifacies ACUA000836 N
ACUA024277 Anopheles culicifacies ACUA024277 N
ADAC008697 Anopheles darlingi ADAC008697 N
ADAC009393 Anopheles darlingi ADAC009393 N
AEPI009636 Anopheles epiroticus AEPI009636 N
AFAF002449 Anopheles farauti AFAF002449 N
AFAF002772 Anopheles farauti AFAF002772 N
AFUN010373 Anopheles funestus AFUN010373 N
AGAP012950 Anopheles gambiae AGAP012950 N
AMAM000172 Anopheles maculatus AMAM000172 N
AMEC000479 Anopheles melas AMEC000479 N
AMEC003904 Anopheles melas AMEC003904 N
AMEM008406 Anopheles merus AMEM008406 N
AMIN002198 Anopheles minimus AMIN002198 N
AQUA006477 Anopheles quadriannulatus AQUA006477 N
ASIS012990 Anopheles sinensis ASIS012990 N
BGIBMGA007797 Bombyx mori BGIBMGA007797 N
Cflo_10942--XP_001121936.1_APIME Camponotus floridanus Cflo_10942--XP_001121936.1_APIME N
CLEC005025 Cimex lectularius CLEC005025 N
CLEC005028 Cimex lectularius CLEC005028 N
CPIJ015425 Culex quinquefasciatus CPIJ015425 N
CpipJ_CPIJ015425 Culex pipiens CpipJ_CPIJ015425 N
DAPPUDRAFT_9525 Daphnia pulex DAPPUDRAFT_9525 N
CG4374 Drosophila melanogaster FBgn0039078 N
GA18142 Drosophila pseudoobscura FBgn0078150 N
GF18765 Drosophila ananassae FBgn0095782 N
GG12435 Drosophila erecta FBgn0104723 N
GH20801 Drosophila grimshawi FBgn0128264 N
GI10710 Drosophila mojavensis FBgn0133474 N
GL13850 Drosophila persimilis FBgn0151455 N
GM23566 Drosophila sechellia FBgn0178432 N
GD18382 Drosophila simulans FBgn0189909 N
GJ23125 Drosophila virilis FBgn0210227 N
GK13158 Drosophila willistoni FBgn0215167 N
GE23956 Drosophila yakuba FBgn0241098 N
GB52523 Apis mellifera GB52523 N
HHAL000145-PA Halyomorpha halys HHAL000145-PA N
HMEL006238 Heliconius melpomene HMEL006238 N
KGM_19023 Danaus plexippus KGM_19023 N
L798_13006 Zootermopsis nevadensis L798_13006 N
LCUP001485 Lucilia cuprina LCUP001485 N
LDEC003260 Leptinotarsa decemlineata LDEC003260 N
MCINX016666 Melitaea cinxia MCINX016666 N
MDOA009050 Musca domestica MDOA009050 N
NV22259 Nasonia vitripennis NV22259 N
PHUM535390 Pediculus humanus PHUM535390 N
PPAI008603 Phlebotomus papatasi PPAI008603 N
SINV21477 Solenopsis invicta SINV21477 N
TC013857 Tribolium castaneum TC013857 N
YQE_03596 Dendroctonus ponderosae YQE_03596 N