TFAP4 (Homo sapiens)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00010 (HLH) IPR001092 ENSG00000090447 T034253_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
TFAP4
M02776_2.00		 Homo sapiens
AWCAGCTGWY
RWCAGCTGWT		 SELEX
Jolma et al.(2013)
TFAP4_1		 (Direct) (Direct)
TFAP4
M02777_2.00		 Homo sapiens
AWCAGCTGWT
AWCAGCTGWT		 SELEX
Jolma et al.(2013)
TFAP4_2		 (Direct) (Direct)
TFAP4
M04066_2.00		 Homo sapiens
VHCAKVTGDB
VHCABMTGDB		 SELEX
Yin et al.(2017)
TFAP4_eDBD_HT-SELEX_1		 (Direct) (Direct)
TFAP4
M04067_2.00		 Homo sapiens
VWCAGCTGWB
VWCAGCTGWB		 SELEX
Yin et al.(2017)
TFAP4_eDBD_HT-SELEX_2		 (Direct) (Direct)
TFAP4
M04068_2.00		 Homo sapiens
DHCABMTGDN
NHCAKVTGDH		 SELEX
Yin et al.(2017)
TFAP4_eDBD_Methyl-HT-SELEX_1		 (Direct) (Direct)
TFAP4
M04069_2.00		 Homo sapiens
AWCAGCTGWT
AWCAGCTGWT		 SELEX
Yin et al.(2017)
TFAP4_eDBD_Methyl-HT-SELEX_2		 (Direct) (Direct)
TFAP4
M04070_2.00		 Homo sapiens
RHCAYVTGDB
VHCABRTGDY		 SELEX
Yin et al.(2017)
TFAP4_FL_HT-SELEX_1		 (Direct) (Direct)
TFAP4
M04071_2.00		 Homo sapiens
VHCAGCTGDB
VHCAGCTGDB		 SELEX
Yin et al.(2017)
TFAP4_FL_HT-SELEX_2		 (Direct) (Direct)
TFAP4
M04072_2.00		 Homo sapiens
VHCABVTGDB
VHCABVTGDB		 SELEX
Yin et al.(2017)
TFAP4_FL_Methyl-HT-SELEX_1		 (Direct) (Direct)
TFAP4
M04073_2.00		 Homo sapiens
VHCAGCTGDB
VHCAGCTGDB		 SELEX
Yin et al.(2017)
TFAP4_FL_Methyl-HT-SELEX_2		 (Direct) (Direct)
TFAP4
M08712_2.00		 Homo sapiens
VMNCAGCTGR
YCAGCTGNKB		 Misc
Kulakovskiy et al.(2013)
TFAP4_HUMAN.H11MO.0.A		 (Direct) (Direct)
TFAP4
M09453_2.00		 Homo sapiens
NVHCAGCTGD
HCAGCTGDBN		 Misc
Heinz et al.(2010)
AML-Tfap4_GSE45738		 (Direct) (Direct)
TFAP4
M09802_2.00		 Homo sapiens
MNGNCHVCAGCTGDBBBW
WVVVHCAGCTGBDGNCNK		 Transfac
Matys et al.(2006)
V$AP4_01		 (Direct) (Direct)
TFAP4
M09803_2.00		 Homo sapiens
NNSAGCTGHB
VDCAGCTSNN		 Transfac
Matys et al.(2006)
V$AP4_Q5		 (Direct) (Direct)
TFAP4
M09804_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$AP4_Q6_01		 (Direct) (Direct)
TFAP4
M09805_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$AP4_Q6_02		 (Direct) (Direct)
TFAP4
M09806_2.00		 Homo sapiens
NVCAGCTGHB
VDCAGCTGBN		 Transfac
Matys et al.(2006)
V$AP4_Q6		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Tfap4
M01717_2.00 		Mus musculus
VHCABVYGB
VCRBVTGDB		 PBM
Weirauch et al.(2014)
pTH5067 		0.724 1.000
crp
M03595_2.00 		Drosophila melanogaster
AACAGCTGWT
AWCAGCTGTT		 SELEX
Nitta et al.(2015)
crp_1 		0.843 0.808
crp
M05937_2.00 		Drosophila melanogaster
VAHCAGCTGAY
RTCAGCTGDWB		 B1H
Zhu et al.(2011)
crp_SANGER_10_FBgn0001994 		0.843 0.808
For this family, TFs with SR scores > 0.838 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000204517 bHLH 49 100
ENSP00000459390 bHLH 1 40

Links

Other bHLH family TFs
Other Homo sapiens TFs

105 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
Aan_R014038 Calypte anna Aan_R014038 I 0.623
ACYPI003006 Acyrthosiphon pisum ACYPI003006 I 0.865
Afo_R007145 Aptenodytes forsteri Afo_R007145 I 0.623
AGAP010201 Anopheles gambiae AGAP010201 I 0.884
Alligator_sinensis_CCG004455.1 Alligator sinensis Alligator_sinensis_CCG004455.1 I 0.914
BGIBMGA010353 Bombyx mori BGIBMGA010353 I 0.854
CapteG45346 Capitella teleta CapteG45346 I 0.903
CGI_10026909 Crassostrea gigas CGI_10026909 I 0.903
Cmyd_10017689 Chelonia mydas Cmyd_10017689 I 0.914
TFAP4 Anolis carolinensis ENSACAG00000016352 I 0.914
ENSAMEG00000002016 Ailuropoda melanoleuca ENSAMEG00000002016 I 0.914
ENSAPLG00000013446 Anas platyrhynchos ENSAPLG00000013446 I 0.890
TFAP4 Bos taurus ENSBTAG00000033174 I 0.914
TFAP4 Canis familiaris ENSCAFG00000019231 I 0.914
ENSCING00000014406 Ciona intestinalis ENSCING00000014406 I 0.912
TFAP4 Callithrix jacchus ENSCJAG00000019756 I 0.914
TFAP4 Cavia porcellus ENSCPOG00000004174 I 0.914
ENSCSAG00000009620 Chlorocebus sabaeus ENSCSAG00000009620 I 0.914
ENSCSAVG00000000333 Ciona savignyi ENSCSAVG00000000333 I 0.912
tfap4 Danio rerio ENSDARG00000103923 I 0.914
TFAP4 Dasypus novemcinctus ENSDNOG00000039193 I 0.914
Tfap4 Dipodomys ordii ENSDORG00000004656 I 0.914
TFAP4 Equus caballus ENSECAG00000022311 I 0.914
TFAP4 Erinaceus europaeus ENSEEUG00000006004 I 0.914
TFAP4 Echinops telfairi ENSETEG00000008634 I 0.914
ENSFALG00000004331 Ficedula albicollis ENSFALG00000004331 I 0.914
TFAP4 Felis catus ENSFCAG00000011227 I 0.914
tfap4 Gasterosteus aculeatus ENSGACG00000011329 I 0.894
tfap4 Gasterosteus aculeatus ENSGACG00000018768 I 0.870
ENSGALG00000027823 Gallus gallus ENSGALG00000027823 I 0.914
TFAP4 Gorilla gorilla ENSGGOG00000000451 I 0.914
ENSGMOG00000014930 Gadus morhua ENSGMOG00000014930 I 0.903
ENSGMOG00000015232 Gadus morhua ENSGMOG00000015232 I 0.901
ENSLACG00000000328 Latimeria chalumnae ENSLACG00000000328 I 0.914
TFAP4 Loxodonta africana ENSLAFG00000022341 I 0.914
ENSLOCG00000002626 Lepisosteus oculatus ENSLOCG00000002626 I 0.914
ENSMEUG00000000888 Macropus eugenii ENSMEUG00000000888 I 0.914
TFAP4 Meleagris gallopavo ENSMGAG00000009411 I 0.914
TFAP4 Myotis lucifugus ENSMLUG00000005725 I 0.914
TFAP4 Monodelphis domestica ENSMODG00000016377 I 0.914
ENSMPUG00000015023 Mustela putorius furo ENSMPUG00000015023 I 0.914
Tfap4 Mus musculus ENSMUSG00000005718 D 0.914
ENSNLEG00000009797 Nomascus leucogenys ENSNLEG00000009797 I 0.914
TFAP4 Ornithorhynchus anatinus ENSOANG00000019858 I 0.914
ENSOARG00000003120 Ovis aries ENSOARG00000003120 I 0.914
TFAP4 Oryctolagus cuniculus ENSOCUG00000024550 I 0.914
TFAP4 Otolemur garnettii ENSOGAG00000008955 I 0.914
ENSONIG00000005196 Oreochromis niloticus ENSONIG00000005196 I 0.914
ENSONIG00000016338 Oreochromis niloticus ENSONIG00000016338 I 0.912
ENSOPRG00000001061 Ochotona princeps ENSOPRG00000001061 I 0.914
tfap4 Oryzias latipes ENSORLG00000008286 I 0.914
tfap4 Oryzias latipes ENSORLG00000015050 I 0.912
ENSP00000204517 Macaca fascicularis ENSP00000204517 I 0.914
ENSP00000204517-D1 Bos grunniens ENSP00000204517-D1 I 0.914
ENSPANG00000010499 Papio anubis ENSPANG00000010499 I 0.914
TFAP4 Procavia capensis ENSPCAG00000011134 I 0.914
ENSPFOG00000000836 Poecilia formosa ENSPFOG00000000836 I 0.912
ENSPFOG00000011355 Poecilia formosa ENSPFOG00000011355 I 0.914
ENSPPYG00000007054 Pongo abelii ENSPPYG00000007054 I 0.914
ENSPSIG00000009002 Pelodiscus sinensis ENSPSIG00000009002 I 0.914
TFAP4 Pan troglodytes ENSPTRG00000007713 I 0.914
ENSPVAG00000005418 Pteropus vampyrus ENSPVAG00000005418 I 0.914
Tfap4 Rattus norvegicus ENSRNOG00000005227 I 0.914
ENSSHAG00000011487 Sarcophilus harrisii ENSSHAG00000011487 I 0.914
ENSSTOG00000028040 Ictidomys tridecemlineatus ENSSTOG00000028040 I 0.914
TFAP4 Tupaia belangeri ENSTBEG00000014089 I 0.914
tfap4 Tetraodon nigroviridis ENSTNIG00000002015 I 0.912
tfap4 Tetraodon nigroviridis ENSTNIG00000009740 I 0.914
tfap4 Tetraodon nigroviridis ENSTNIG00000014095 I 0.912
tfap4 Takifugu rubripes ENSTRUG00000006111 I 0.914
tfap4 Takifugu rubripes ENSTRUG00000013344 I 0.912
TFAP4 Tursiops truncatus ENSTTRG00000002710 I 0.914
TFAP4 Vicugna pacos ENSVPAG00000008001 I 0.914
ENSXMAG00000004632 Xiphophorus maculatus ENSXMAG00000004632 I 0.914
ENSXMAG00000011968 Xiphophorus maculatus ENSXMAG00000011968 I 0.912
estExt_fgenesh2_pg.C_3260041 Branchiostoma floridae estExt_fgenesh2_pg.C_3260041 I 0.914
crp Drosophila melanogaster FBgn0001994 D 0.843
GA20511 Drosophila pseudoobscura FBgn0080505 I 0.843
GF21721 Drosophila ananassae FBgn0098721 I 0.843
GG24179 Drosophila erecta FBgn0116312 I 0.843
GH10096 Drosophila grimshawi FBgn0117577 I 0.843
GI14377 Drosophila mojavensis FBgn0137129 I 0.843
GL14101 Drosophila persimilis FBgn0151706 I 0.843
GM17917 Drosophila sechellia FBgn0172824 I 0.843
GD21926 Drosophila simulans FBgn0193342 I 0.843
GJ16254 Drosophila virilis FBgn0203439 I 0.843
GK24289 Drosophila willistoni FBgn0226250 I 0.843
GE19372 Drosophila yakuba FBgn0236717 I 0.843
fgenesh2_pg.scaffold_326000054 Branchiostoma floridae fgenesh2_pg.scaffold_326000054 I 0.914
GB48999 Apis mellifera GB48999 I 0.884
HMEL008759 Heliconius melpomene HMEL008759 I 0.854
KGM_15765 Danaus plexippus KGM_15765 I 0.854
L798_07621 Zootermopsis nevadensis L798_07621 I 0.884
LLOJ009485 Lutzomyia longipalpis LLOJ009485 I 0.884
MDOA012071 Musca domestica MDOA012071 I 0.843
Myotis_brandtii_TFAP4_10028039 Myotis brandtii Myotis_brandtii_TFAP4_10028039 I 0.914
Ocbimv22002701m.g Octopus bimaculoides Ocbimv22002701m.g N 0.873
Ogr05167 Ophisaurus gracilis Ogr05167 I 0.914
Pvit_18996 Pogona vitticeps Pvit_18996 I 0.914
Sakowv30040946m.g Saccoglossus kowalevskii Sakowv30040946m.g I 0.880
SPU_003179 Strongylocentrotus purpuratus SPU_003179 I 0.852
TCLT_0000678201 Thelazia callipaeda TCLT_0000678201 I 0.846
tetur30g00270 Tetranychus urticae tetur30g00270 I 0.860
tfap4 Xenopus tropicalis XB-GENE-999265 I 0.914