CIS-BP Database: Catalog of Inferred Sequence Binding Preferences

TF Information

SOHLH2 *(Homo sapiens)* bHLH
Pfam ID	Interpro ID	Gene ID	CIS-BP ID	Sequence source	Animal TF db
PF00010 (HLH)	IPR001092	ENSG00000120669	T034271_2.00	Ensembl (2018-Dec-8)	Link out
Directly determined binding motifs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
SOHLH2 M01113_2.00	Homo sapiens	BCACGDRNN	NNYHCGTGV	PBM Lambert et al.(2019) pTH11270	(Direct)	(Direct)
SOHLH2 M04096_2.00	Homo sapiens	NBCACGTGCN	NGCACGTGVN	SELEX Yin et al.(2017) SOHLH2_eDBD_HT-SELEX	(Direct)	(Direct)
SOHLH2 M04097_2.00	Homo sapiens	NNMACGWDNN	NNHWCGTKNN	SELEX Yin et al.(2017) SOHLH2_eDBD_Methyl-HT-SELEX	(Direct)	(Direct)
Motifs from related TFs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
Sohlh2 M09890_2.00	Rattus norvegicus	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$TEB1_01	0.849	0.860
Sohlh2 M01733_2.00	Mus musculus	NNHNCGTGVN	NBCACGNDNN	PBM Weirauch et al.(2014) pTH5058	0.849	0.840
For this family, TFs with SR scores > 0.838* will likely have a similar motif*

Experimental Constructs

Motif ID	Domain	From	To	Sequence
M01113_2.00	bHLH	51	100	LLHSSKEKLRRERIKYCCEQLRTLLPYVKGRKNDAASVLEATVDYVKYIR

DNA Binding Domains

Protein ID	Domain	From	To	Sequence
ENSP00000369210	bHLH	204	253	LLHSSKEKLRRERIKYCCEQLRTLLPYVKGRKNDAASVLEATVDYVKYIR

Links
Other bHLH family TFs
Other *Homo sapiens* TFs