BACH2 (Homo sapiens)
bZIP

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00170 (bZIP_1) IPR011616 ENSG00000112182 T059730_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables sequence-specific double-stranded DNA binding activity. Involved in primary adaptive immune response involving T cells and B cells. Located in cytosol and nucleoplasm. Implicated in immunodeficiency 60. [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
BACH2
M04247_2.00		 Homo sapiens
NWWNCATGASTCATSNHWN
NWDNSATGASTCATGNWWN		 SELEX
Yin et al.(2017)
BACH2_eDBD_HT-SELEX_1		 (Direct) (Direct)
BACH2
M04248_2.00		 Homo sapiens
DWANSATGACGTSATSNTWD
HWANSATSACGTCATSNTWH		 SELEX
Yin et al.(2017)
BACH2_eDBD_HT-SELEX_2		 (Direct) (Direct)
BACH2
M04249_2.00		 Homo sapiens
NWANCATGASTCATSNWWN
NWWNSATGASTCATGNTWN		 SELEX
Yin et al.(2017)
BACH2_eDBD_Methyl-HT-SELEX		 (Direct) (Direct)
BACH2
M08065_2.00		 Homo sapiens
NVTGACTCAGCANN
NNTGCTGAGTCABN		 ChIP-seq
Mathelier et al.(2014)
MA1101.1		 (Direct) (Direct)
BACH2
M08787_2.00		 Homo sapiens
VTGASTCAGCA
TGCTGASTCAB		 Misc
Kulakovskiy et al.(2013)
BACH2_HUMAN.H11MO.0.A		 (Direct) (Direct)
BACH2
M09484_2.00		 Homo sapiens
TGASTCAGCN
NGCTGASTCA		 Misc
Heinz et al.(2010)
OCILy7-Bach2_GSE44420		 (Direct) (Direct)
BACH2
M09938_2.00		 Homo sapiens
BVTGACKCAYS
SRTGMGTCABV		 Transfac
Matys et al.(2006)
V$BACH2_01		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Bach2
M08832_2.00 		Mus musculus
RTGACTCAGCN
NGCTGAGTCAY		 Misc
Kulakovskiy et al.(2013)
BACH2_MOUSE.H11MO.0.A 		0.935 0.967
BACH1
M08184_2.00 		Homo sapiens
RTCACGTG
CACGTGAY		 ChIP-seq
Contrino et al.(2012)
Mv45 		0.838 0.689
BACH1
M08185_2.00 		Homo sapiens
TGASTCAGCA
TGCTGASTCA		 ChIP-seq
Contrino et al.(2012)
Mv46 		0.838 0.689
BACH1
M08186_2.00 		Homo sapiens
TCAGCADTT
AAHTGCTGA		 ChIP-seq
Contrino et al.(2012)
Mv47 		0.838 0.689
BACH1
M08800_2.00 		Homo sapiens
VNVTGACTCAGCA
TGCTGAGTCABNB		 Misc
Kulakovskiy et al.(2013)
BACH1_HUMAN.H11MO.0.A 		0.838 0.689
Bach1
M08823_2.00 		Mus musculus
ASCRTGACTCAGCR
YGCTGAGTCAYGST		 Misc
Kulakovskiy et al.(2013)
BACH1_MOUSE.H11MO.0.C 		0.838 0.689
BACH1
M09488_2.00 		Homo sapiens
RTGACTCAGCANWWH
DWWNTGCTGAGTCAY		 Misc
Heinz et al.(2010)
K562-Bach1_GSE31477 		0.838 0.689
BACH1
M09975_2.00 		Homo sapiens
VNBATGACTCATSNB
VNSATGAGTCATVNB		 Transfac
Matys et al.(2006)
V$BACH1_01 		0.838 0.689
BACH1
M09976_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$BACH1_Q3 		0.838 0.689
For this family, TFs with SR scores > 0.782 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000257749 bZIP 647 707
ENSP00000345642 bZIP 647 707
ENSP00000437473 bZIP 647 707

Links

Other bZIP family TFs
Other Homo sapiens TFs

Invalid Input OrderBy

149 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action