ZNF281 (Homo sapiens)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSG00000162702 T095017_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
ZNF281
M04509_2.00
Homo sapiens
SCCCCTCCCCCM

KGGGGGAGGGGS
SELEX
Yin et al.(2017)
ZNF281_eDBD_HT-SELEX
(Direct) (Direct)
ZNF281
M04510_2.00
Homo sapiens
RCCCMTCCCCCR

YGGGGGAKGGGY
SELEX
Yin et al.(2017)
ZNF281_eDBD_Methyl-HT-SELEX
(Direct) (Direct)
ZNF281
M08321_2.00
Homo sapiens
BNCCCCTCCCCC

GGGGGAGGGGNV
ChIP-seq
Schmitges et al.(2016)
Q9Y2X9_1-4.RCADE
(Direct) (Direct)
ZNF281
M08906_2.00
Homo sapiens
BCCCCTCCCCCHNYN

NRNDGGGGGAGGGGV
Misc
Kulakovskiy et al.(2013)
ZN281_HUMAN.H11MO.0.A
(Direct) (Direct)
ZNF281
M10237_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$ZFP281_01
(Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
Zfp281
M00139_2.00
Mus musculus
NHDCCCCCHH

DDGGGGGHDN
PBM
Badis et al.(2009)
Zfp281_0973
0.827 1.000
Zfp281
M08025_2.00
Mus musculus
CCCCWCCCCCMVCHB

VDGBKGGGGGWGGGG
ChIP-seq
Chen et al.(2011)
GSE11329_zfp281
0.827 1.000
Zfp281
M08999_2.00
Mus musculus
CCCCTCCCCCMMCBB

VVGKKGGGGGAGGGG
Misc
Kulakovskiy et al.(2013)
ZN281_MOUSE.H11MO.0.A
0.827 1.000
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000294740 C2H2 ZF 261 283
ENSP00000294740 C2H2 ZF 289 311
ENSP00000294740 C2H2 ZF 317 339
ENSP00000294740 C2H2 ZF 345 366
ENSP00000356321 C2H2 ZF 225 247
ENSP00000356321 C2H2 ZF 253 275
ENSP00000356321 C2H2 ZF 281 303
ENSP00000356321 C2H2 ZF 309 330
ENSP00000356322 C2H2 ZF 261 283
ENSP00000356322 C2H2 ZF 289 311
ENSP00000356322 C2H2 ZF 317 339
ENSP00000356322 C2H2 ZF 345 366

Links

Other C2H2 ZF family TFs
Other Homo sapiens TFs

67 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
MDP0000315706 Malus domestica MDP0000315706 N
Pm019863 Prunus mume Pm019863 N
PRUPE_ppa002688mg Prunus persica PRUPE_ppa002688mg N