ZNF454 (Homo sapiens)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSG00000178187 T095166_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
ZNF454
M04571_2.00		 Homo sapiens
WRGCGCCWGGCGCYW
WRGCGCCWGGCGCYW		 SELEX
Yin et al.(2017)
ZNF454_eDBD_HT-SELEX_1		 (Direct) (Direct)
ZNF454
M04572_2.00		 Homo sapiens
TRGCGCCGGCGCYN
NRGCGCCGGCGCYA		 SELEX
Yin et al.(2017)
ZNF454_eDBD_HT-SELEX_2		 (Direct) (Direct)
ZNF454
M04573_2.00		 Homo sapiens
WRGCGCCWGGCGCYW
WRGCGCCWGGCGCYW		 SELEX
Yin et al.(2017)
ZNF454_eDBD_Methyl-HT-SELEX_1		 (Direct) (Direct)
ZNF454
M04574_2.00		 Homo sapiens
TRGCGCCGGCGCYN
NRGCGCCGGCGCYA		 SELEX
Yin et al.(2017)
ZNF454_eDBD_Methyl-HT-SELEX_2		 (Direct) (Direct)
ZNF454
M07651_2.00		 Homo sapiens
CRKVVRHCCVYCRGGVCCBVGAGCCNKYB
VRMNGGCTCBVGGBCCYGRBRGDYBBMYG		 ChIP-seq+ChIP-exo
Barazandeh et al.(2018)
ZNF454.MEME.OriginalMapping		 (Direct) (Direct)
ZNF454
M08256_2.00		 Homo sapiens
GWGCYTT
AARGCWC		 ChIP-seq
Najafabadi et al.(2015b)
ZNF454		 (Direct) (Direct)
ZNF454
M08346_2.00		 Homo sapiens
KVVRNCHNYMRGGGCCNDGDGCCWTTB
VAAWGGCHCHNGGCCCYKRNDGNYBBM		 ChIP-seq
Schmitges et al.(2016)
Q8N9F8_4-12.RCADE		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000326249 C2H2 ZF 178 200
ENSP00000326249 C2H2 ZF 216 238
ENSP00000326249 C2H2 ZF 244 266
ENSP00000326249 C2H2 ZF 272 294
ENSP00000326249 C2H2 ZF 300 322
ENSP00000326249 C2H2 ZF 328 350
ENSP00000326249 C2H2 ZF 356 378
ENSP00000326249 C2H2 ZF 384 406
ENSP00000326249 C2H2 ZF 412 434
ENSP00000326249 C2H2 ZF 440 462
ENSP00000326249 C2H2 ZF 468 490
ENSP00000326249 C2H2 ZF 496 518
ENSP00000430354 C2H2 ZF 178 200
ENSP00000430354 C2H2 ZF 216 238
ENSP00000430354 C2H2 ZF 244 266
ENSP00000430354 C2H2 ZF 272 294
ENSP00000430354 C2H2 ZF 300 322
ENSP00000430354 C2H2 ZF 328 350
ENSP00000430354 C2H2 ZF 356 378
ENSP00000430354 C2H2 ZF 384 406
ENSP00000430354 C2H2 ZF 412 434
ENSP00000430354 C2H2 ZF 440 462
ENSP00000430354 C2H2 ZF 468 490
ENSP00000430354 C2H2 ZF 496 518

Links

Other C2H2 ZF family TFs
Other Homo sapiens TFs

27 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ANIA_03769 Aspergillus nidulans CADANIAG00004949 D
MAC_06259 Metarhizium acridum MAC_06259 N
MAJ_08664 Metarhizium majus MAJ_08664 I
MANI_010873 Metarhizium anisopliae MANI_010873 I
MGU_08935 Metarhizium guizhouense MGU_08935 I
S40285_07224 Stachybotrys chlorohalonata S40285_07224 I
S40288_05556 Stachybotrys chartarum S40288_05556 I
TRIATDRAFT_182375 Trichoderma atroviride TRIATDRAFT_182375 I
TRIREDRAFT_3605 Trichoderma reesei TRIREDRAFT_3605 I
TRIVIDRAFT_124610 Trichoderma virens TRIVIDRAFT_124610 I
X797_010537 Metarhizium robertsii X797_010537 I