EGR1 (Gallus gallus)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSGALG00000007669 T095883_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Egr1
M01864_2.00 		Mus musculus
CCCMCGYNN
NNRCGKGGG		 PBM
Weirauch et al.(2014)
pTH5337 		0.827 1.000
Egr1
M00375_2.00 		Mus musculus
NCCYMCDNN
NNHGKRGGN		 PBM
Berger et al.(2006)
Zif268 		0.827 1.000
EGR1
M02883_2.00 		Homo sapiens
NMCGCCCMCGCANN
NNTGCGKGGGCGKN		 SELEX
Jolma et al.(2013)
EGR1_1 		0.827 1.000
EGR1
M02884_2.00 		Homo sapiens
HMCGCCCACGCAHW
WDTGCGTGGGCGKD		 SELEX
Jolma et al.(2013)
EGR1_2 		0.827 1.000
Egr1
M02932_2.00 		Mus musculus
HHMCGCCCMCBCAHHH
DDDTGVGKGGGCGKDD		 SELEX
Jolma et al.(2013)
Egr1_1 		0.827 1.000
EGR1
M04437_2.00 		Homo sapiens
NNCRCCCMCRCNN
NNGYGKGGGYGNN		 SELEX
Yin et al.(2017)
EGR1_eDBD_HT-SELEX 		0.827 1.000
Egr1
M05860_2.00 		Mus musculus
NNMCRCCCMCGCN
NGCGKGGGYGKNN		 SMiLE-seq
Isakova et al.(2017)
EGR1 		0.827 1.000
EGR1
M07927_2.00 		Homo sapiens
NVBNNNNBCCGCCCMCGCNB
VNGCGKGGGCGGVNNNNVBN		 ChIP-seq
Gerstein et al.(2012)
GM12878_EGR1_HudsonAlpha 		0.827 1.000
EGR1
M07928_2.00 		Homo sapiens
BNCCGCCCMCGCNBB
VVNGCGKGGGCGGNV		 ChIP-seq
Gerstein et al.(2012)
H1-hESC_EGR1_HudsonAlpha 		0.827 1.000
EGR1
M07929_2.00 		Homo sapiens
NNNNNNBNNCCRCCCMCGCN
NGCGKGGGYGGNNVNNNNNN		 ChIP-seq
Gerstein et al.(2012)
K562_EGR1_HudsonAlpha 		0.827 1.000
EGR1
M08882_2.00 		Homo sapiens
BHNCCDCCCMCDCHBNB
VNVDGHGKGGGHGGNDV		 Misc
Kulakovskiy et al.(2013)
EGR1_HUMAN.H11MO.0.A 		0.827 1.000
Egr1
M08996_2.00 		Mus musculus
YYCCRCCCMCGCNB
VNGCGKGGGYGGRR		 Misc
Kulakovskiy et al.(2013)
EGR1_MOUSE.H11MO.0.A 		0.827 1.000
EGR1
M09506_2.00 		Homo sapiens
CRCCCMCRCA
TGYGKGGGYG		 Misc
Heinz et al.(2010)
K562-Egr1_GSE32465 		0.827 1.000
EGR1
M10188_2.00 		Homo sapiens
MCGCCYACGCAW
WTGCGTRGGCGK		 Transfac
Matys et al.(2006)
V$EGR1_01 		0.827 1.000
EGR1
M10189_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$EGR1_02 		0.827 1.000
EGR1
M10190_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$EGR1_09 		0.827 1.000
EGR1
M10191_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$EGR1_11 		0.827 1.000
EGR1
M10192_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$EGR1_12 		0.827 1.000
EGR1
M10193_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$EGR1_13 		0.827 1.000
EGR1
M10194_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$EGR1_15 		0.827 1.000
EGR1
M10195_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$EGR1_Q3 		0.827 1.000
EGR1
M10196_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$EGR1_Q6 		0.827 1.000
EGR1
M04438_2.00 		Homo sapiens
NHCDCCCMCNYNN
NNRNGKGGGHGDN		 SELEX
Yin et al.(2017)
EGR1_eDBD_Methyl-HT-SELEX 		0.827 1.000
Egr3
M00776_2.00 		Mus musculus
HHDCCCMCDN
NHGKGGGHDD		 PBM
Weirauch et al.(2013)
pTH2820 		0.816 0.899
EGR3
M02915_2.00 		Homo sapiens
NHMCGCCCMCGCAHN
NDTGCGKGGGCGKDN		 SELEX
Jolma et al.(2013)
EGR3_1 		0.816 0.899
Egr3
M02931_2.00 		Mus musculus
HMCGCCCACGCAHWN
NWDTGCGTGGGCGKD		 SELEX
Jolma et al.(2013)
Egr3_1 		0.816 0.899
EGR3
M04583_2.00 		Homo sapiens
HMCGCCCACGCRH
DYGCGTGGGCGKD		 SELEX
Yin et al.(2017)
EGR3_FL_HT-SELEX 		0.816 0.899
EGR3
M08349_2.00 		Homo sapiens
CDCCYCCDC
GHGGRGGHG		 ChIP-seq
Schmitges et al.(2016)
Q06889_1-3.RCADE 		0.816 0.899
EGR3
M10279_2.00 		Homo sapiens
MCGCCYACGCWN
NWGCGTRGGCGK		 Transfac
Matys et al.(2006)
V$EGR3_01 		0.816 0.899
EGR3
M10280_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$EGR3_Q3 		0.816 0.899
EGR3
M10281_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$EGR3_Q6 		0.816 0.899
EGR3
M04584_2.00 		Homo sapiens
NMCGCCCACGCRH
DYGCGTGGGCGKN		 SELEX
Yin et al.(2017)
EGR3_FL_Methyl-HT-SELEX 		0.816 0.899
EGR4
M02889_2.00 		Homo sapiens
NHMCGCCCACGCAHHN
NDDTGCGTGGGCGKDN		 SELEX
Jolma et al.(2013)
EGR4_1 		0.804 0.812
EGR4
M02890_2.00 		Homo sapiens
NHMCGCCCACGCAHWH
DWDTGCGTGGGCGKDN		 SELEX
Jolma et al.(2013)
EGR4_2 		0.804 0.812
EGR4
M04461_2.00 		Homo sapiens
HMCGCCCACGCAH
DTGCGTGGGCGKD		 SELEX
Yin et al.(2017)
EGR4_eDBD_HT-SELEX 		0.804 0.812
EGR4
M10216_2.00 		Homo sapiens
MCRCCCACGCAW
WTGCGTGGGYGK		 Transfac
Matys et al.(2006)
V$NGFIC_01 		0.804 0.812
EGR4
M04462_2.00 		Homo sapiens
HMCGCCCMCGCRH
DYGCGKGGGCGKD		 SELEX
Yin et al.(2017)
EGR4_eDBD_Methyl-HT-SELEX 		0.804 0.812
EGR2
M00233_2.00 		Homo sapiens
HDCCCMCDBN
NVHGKGGGHD		 PBM
Barrera et al.(2016)
EGR2_REF 		0.803 0.957
Egr2
M00778_2.00 		Mus musculus
YRCCCMCGYN
NRCGKGGGYR		 PBM
Weirauch et al.(2013)
pTH3091 		0.803 0.957
EGR2
M02885_2.00 		Homo sapiens
MCGCCCACGCD
HGCGTGGGCGK		 SELEX
Jolma et al.(2013)
EGR2_1 		0.803 0.957
EGR2
M02886_2.00 		Homo sapiens
NNMCGCCCACGCDNN
NNHGCGTGGGCGKNN		 SELEX
Jolma et al.(2013)
EGR2_2 		0.803 0.957
EGR2
M04439_2.00 		Homo sapiens
HMCRCCCACGCNN
NNGCGTGGGYGKD		 SELEX
Yin et al.(2017)
EGR2_FL_HT-SELEX 		0.803 0.957
EGR2
M08302_2.00 		Homo sapiens
CDCCCMCDC
GHGKGGGHG		 ChIP-seq
Schmitges et al.(2016)
P11161_1-3.RCADE 		0.803 0.957
EGR2
M08884_2.00 		Homo sapiens
YYCCDCCCMCDCHYHYHY
RDRDRDGHGKGGGHGGRR		 Misc
Kulakovskiy et al.(2013)
EGR2_HUMAN.H11MO.0.A 		0.803 0.957
Egr2
M08994_2.00 		Mus musculus
BHYCCDCCCMCDCN
NGHGKGGGHGGRDV		 Misc
Kulakovskiy et al.(2013)
EGR2_MOUSE.H11MO.0.A 		0.803 0.957
Egr2
M09515_2.00 		Mus musculus
NMCRCCCACDSN
NSHGTGGGYGKN		 Misc
Heinz et al.(2010)
Thymocytes-Egr2_GSE34254 		0.803 0.957
EGR2
M10197_2.00 		Homo sapiens
MCGCCYACGCAH
DTGCGTRGGCGK		 Transfac
Matys et al.(2006)
V$EGR2_01 		0.803 0.957
EGR2
M10198_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$EGR2_Q4 		0.803 0.957
EGR2
M10199_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$EGR2_Q6 		0.803 0.957
EGR2
M04440_2.00 		Homo sapiens
NMCGCCCACRCRN
NYGYGTGGGCGKN		 SELEX
Yin et al.(2017)
EGR2_FL_Methyl-HT-SELEX 		0.803 0.957
EGR2
M00232_2.00 		Homo sapiens
NHMCGCCYNN
NNRGGCGKDN		 PBM
Barrera et al.(2016)
EGR2_R409W 		0.802 0.942
sr
M06072_2.00 		Drosophila melanogaster
HVMCGCCCMCVYMH
DKRBGKGGGCGKBD		 B1H
Zhu et al.(2011)
sr_SANGER_5_FBgn0003499 		0.801 0.913
sr
M06073_2.00 		Drosophila melanogaster
NNMCRCCCMCVHNN
NNDBGKGGGYGKNN		 B1H
Zhu et al.(2011)
sr_SOLEXA_5_FBgn0003499 		0.801 0.913
egrh-1
M00622_2.00 		Caenorhabditis elegans
CSCCCMCR
YGKGGGSG		 PBM
Narasimhan et al.(2015)
pTH9317 		0.785 0.899
EGR2
M00231_2.00 		Homo sapiens
MCCMCGCD
HGCGKGGK		 PBM
Barrera et al.(2016)
EGR2_R359W 		0.757 0.942
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSGALP00000012417 C2H2 ZF 310 334
ENSGALP00000012417 C2H2 ZF 340 362
ENSGALP00000012417 C2H2 ZF 368 390

Links

Other C2H2 ZF family TFs
Other Gallus gallus TFs

370 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
Aan_R003668 Calypte anna Aan_R003668 I
Aan_R014758 Calypte anna Aan_R014758 I
Afo_R004007 Aptenodytes forsteri Afo_R004007 I
Afo_R008251 Aptenodytes forsteri Afo_R008251 I
Alligator_sinensis_CCG011250.1 Alligator sinensis Alligator_sinensis_CCG011250.1 I
Alligator_sinensis_CCG014066.1 Alligator sinensis Alligator_sinensis_CCG014066.1 I
Brh_R001493 Buceros rhinoceros Brh_R001493 I
Brh_R005182 Buceros rhinoceros Brh_R005182 I
Cmyd_10009615 Chelonia mydas Cmyd_10009615 I
Cmyd_10021057 Chelonia mydas Cmyd_10021057 I
ZNF281 Anolis carolinensis ENSACAG00000006286 I
ZNF148 Anolis carolinensis ENSACAG00000010047 I
ENSAMEG00000004258 Ailuropoda melanoleuca ENSAMEG00000004258 I
ENSAMXG00000006043 Astyanax mexicanus ENSAMXG00000006043 I
ENSAPLG00000008859 Anas platyrhynchos ENSAPLG00000008859 I
ZNF148 Bos taurus ENSBTAG00000040031 I
ZNF148 Canis familiaris ENSCAFG00000012574 I
ZNF148 Callithrix jacchus ENSCJAG00000006741 I
znf148 Danio rerio ENSDARG00000055106 I
ZNF148 Dasypus novemcinctus ENSDNOG00000000280 I
ENSDORG00000003955 Dipodomys ordii ENSDORG00000003955 I
ZNF148 Echinops telfairi ENSETEG00000002856 I
ENSFALG00000013520 Ficedula albicollis ENSFALG00000013520 I
ENSFALG00000014467 Ficedula albicollis ENSFALG00000014467 I
ZNF148 Felis catus ENSFCAG00000026852 I
ZNF148 Homo sapiens ENSG00000163848 D
ZNF148 Gallus gallus ENSGALG00000012049 I
ENSLACG00000006364 Latimeria chalumnae ENSLACG00000006364 I
ZNF148 Loxodonta africana ENSLAFG00000016025 I
ENSLOCG00000002769 Lepisosteus oculatus ENSLOCG00000002769 I
ZNF148 Macaca mulatta ENSMMUG00000001169 I
ZNF148 Monodelphis domestica ENSMODG00000018374 I
ENSMPUG00000004162 Mustela putorius furo ENSMPUG00000004162 I
Zfp148 Mus musculus ENSMUSG00000022811 I
ENSNLEG00000000773 Nomascus leucogenys ENSNLEG00000000773 I
ZNF281 Ornithorhynchus anatinus ENSOANG00000004857 I
ENSOARG00000020237 Ovis aries ENSOARG00000020237 I
ZNF148 Otolemur garnettii ENSOGAG00000013652 I
ENSONIG00000004240 Oreochromis niloticus ENSONIG00000004240 I
ZNF148 Ochotona princeps ENSOPRG00000010519 I
znf148 Oryzias latipes ENSORLG00000015950 I
ENSP00000420448 Macaca fascicularis ENSP00000420448 I
ENSP00000420448-D1 Bos grunniens ENSP00000420448-D1 I
ENSPANG00000004284 Papio anubis ENSPANG00000004284 I
ENSPFOG00000004115 Poecilia formosa ENSPFOG00000004115 I
ENSPPYG00000013462 Pongo abelii ENSPPYG00000013462 I
ENSPSIG00000003614 Pelodiscus sinensis ENSPSIG00000003614 I
ZNF148 Pteropus vampyrus ENSPVAG00000006133 I
Zfp148 Rattus norvegicus ENSRNOG00000001789 I
ZNF148 Sorex araneus ENSSARG00000007257 I
ENSSHAG00000013855 Sarcophilus harrisii ENSSHAG00000013855 I
ZNF148 Sus scrofa ENSSSCG00000011858 I
ENSSTOG00000027082 Ictidomys tridecemlineatus ENSSTOG00000027082 I
ZNF148 Tupaia belangeri ENSTBEG00000008435 I
ZNF148 Taeniopygia guttata ENSTGUG00000004010 I
ZNF281 Taeniopygia guttata ENSTGUG00000004438 I
znf148 Takifugu rubripes ENSTRUG00000006270 I
ZNF148 Tursiops truncatus ENSTTRG00000014714 I
Gfo_R001184 Geospiza fortis Gfo_R001184 I
Gfo_R006633 Geospiza fortis Gfo_R006633 I
Ogr00130 Ophisaurus gracilis Ogr00130 I
Pvit_03082 Pogona vitticeps Pvit_03082 I
Pvit_14619 Pogona vitticeps Pvit_14619 I
Tal_R010113 Tyto alba Tal_R010113 I
Tal_R010256 Tyto alba Tal_R010256 I
znf148 Xenopus tropicalis XB-GENE-996852 I