KLF4 (Monodelphis domestica)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSMODG00000014569 T100034_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
KLF4
M04463_2.00 		Homo sapiens
NVCCACRCCCH
DGGGYGTGGBN		 SELEX
Yin et al.(2017)
KLF4_eDBD_HT-SELEX 		0.827 1.000
KLF4
M08091_2.00 		Homo sapiens
MCACACCCWNN
NNWGGGTGTGK		 ChIP-seq
Mathelier et al.(2014)
MA0039.3 		0.827 1.000
Klf4
M08021_2.00 		Mus musculus
VRCCMCRCCCH
DGGGYGKGGYB		 ChIP-seq
Chen et al.(2011)
SRP000217_Klf4 		0.827 1.000
KLF4
M08243_2.00 		Homo sapiens
RCCMCRCCCH
DGGGYGKGGY		 ChIP-seq
Najafabadi et al.(2015b)
KLF14 		0.827 1.000
KLF4
M08894_2.00 		Homo sapiens
RCCMCRCCCH
DGGGYGKGGY		 Misc
Kulakovskiy et al.(2013)
KLF4_HUMAN.H11MO.0.A 		0.827 1.000
Klf4
M08964_2.00 		Mus musculus
GCCMCRCCCWBYBBN
NVVRVWGGGYGKGGC		 Misc
Kulakovskiy et al.(2013)
KLF4_MOUSE.H11MO.0.A 		0.827 1.000
KLF4
M10217_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$GKLF_02 		0.827 1.000
KLF4
M10218_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$GKLF_Q3_01 		0.827 1.000
KLF4
M10219_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$GKLF_Q3 		0.827 1.000
KLF4
M10220_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$GKLF_Q4 		0.827 1.000
KLF4
M04464_2.00 		Homo sapiens
NVCCMCRCCCN
NGGGYGKGGBN		 SELEX
Yin et al.(2017)
KLF4_eDBD_Methyl-HT-SELEX 		0.827 1.000
KLF2
M04455_2.00 		Homo sapiens
NVCCMCRCCCH
DGGGYGKGGBN		 SELEX
Yin et al.(2017)
KLF2_eDBD_HT-SELEX 		0.813 0.942
KLF2
M10210_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$LKLF_Q3 		0.813 0.942
KLF2
M10211_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$LKLF_Q6 		0.813 0.942
KLF2
M04456_2.00 		Homo sapiens
NVCCMCRCCCN
NGGGYGKGGBN		 SELEX
Yin et al.(2017)
KLF2_eDBD_Methyl-HT-SELEX 		0.813 0.942
KLF1
M00226_2.00 		Homo sapiens
CMCGCCCM
KGGGCGKG		 PBM
Barrera et al.(2016)
KLF1_REF 		0.784 0.884
KLF1
M08293_2.00 		Homo sapiens
NVNNNRCCMCRCCCH
DGGGYGKGGYNNNBN		 ChIP-seq
Schmitges et al.(2016)
Q13351.MEME 		0.784 0.884
KLF1
M08871_2.00 		Homo sapiens
SVNDGCCMCRCCCH
DGGGYGKGGCHNBS		 Misc
Kulakovskiy et al.(2013)
KLF1_HUMAN.H11MO.0.A 		0.784 0.884
KLF1
M10163_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$EKLF_Q5_01 		0.784 0.884
KLF1
M10164_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$EKLF_Q5 		0.784 0.884
KLF1
M00224_2.00 		Homo sapiens
YMCGCCCH
DGGGCGKR		 PBM
Barrera et al.(2016)
KLF1_H299Y 		0.784 0.870
KLF5
M04410_2.00 		Homo sapiens
NMCACRCCCH
DGGGYGTGKN		 SELEX
Yin et al.(2017)
KLF5_eDBD_HT-SELEX 		0.784 0.841
KLF5
M08086_2.00 		Homo sapiens
BCCMCDCCCH
DGGGHGKGGV		 ChIP-seq
Mathelier et al.(2014)
MA0599.1 		0.784 0.841
KLF5
M08868_2.00 		Homo sapiens
NHVNRCCMCDCCCH
DGGGHGKGGYNBDN		 Misc
Kulakovskiy et al.(2013)
KLF5_HUMAN.H11MO.0.A 		0.784 0.841
Klf5
M08965_2.00 		Mus musculus
KCCMCDCCCHBBBCH
DGVVVDGGGHGKGGM		 Misc
Kulakovskiy et al.(2013)
KLF5_MOUSE.H11MO.0.A 		0.784 0.841
KLF5
M09502_2.00 		Homo sapiens
GCCMCRCCCH
DGGGYGKGGC		 Misc
Heinz et al.(2010)
LoVo-KLF5_GSE49402 		0.784 0.841
KLF5
M10149_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$BTEB2_Q3_01 		0.784 0.841
KLF5
M10150_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$BTEB2_Q3 		0.784 0.841
KLF5
M04411_2.00 		Homo sapiens
NMCACRCCYH
DRGGYGTGKN		 SELEX
Yin et al.(2017)
KLF5_eDBD_Methyl-HT-SELEX 		0.784 0.841
KLF3
M04418_2.00 		Homo sapiens
RRCCRCGCCCH
DGGGCGYGGYY		 SELEX
Yin et al.(2017)
KLF3_FL_HT-SELEX 		0.784 0.826
KLF3
M08876_2.00 		Homo sapiens
NSNNVCCMCRCCCHBBBBN
NVVVVDGGGYGKGGBNNSN		 Misc
Kulakovskiy et al.(2013)
KLF3_HUMAN.H11MO.0.B 		0.784 0.826
Klf3
M08982_2.00 		Mus musculus
NSNNVCCMCRCCCHBBBBN
NVVVVDGGGYGKGGBNNSN		 Misc
Kulakovskiy et al.(2013)
KLF3_MOUSE.H11MO.0.A 		0.784 0.826
KLF3
M10172_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$KLF3_Q3_01 		0.784 0.826
KLF3
M10173_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$KLF3_Q3 		0.784 0.826
KLF3
M04419_2.00 		Homo sapiens
DRCCACGCCCH
DGGGCGTGGYH		 SELEX
Yin et al.(2017)
KLF3_FL_Methyl-HT-SELEX_1 		0.784 0.826
KLF3
M04420_2.00 		Homo sapiens
RRSCGCARCCCN
NGGGYTGCGSYY		 SELEX
Yin et al.(2017)
KLF3_FL_Methyl-HT-SELEX_2 		0.784 0.826
Klf1
M08099_2.00 		Mus musculus
NRCCACACCCW
WGGGTGTGGYN		 ChIP-seq
Mathelier et al.(2014)
MA0493.1 		0.781 0.855
Klf1
M09008_2.00 		Mus musculus
MVMNSCCMCRCCCH
DGGGYGKGGSNKBK		 Misc
Kulakovskiy et al.(2013)
KLF1_MOUSE.H11MO.0.A 		0.781 0.855
Klf1
M09516_2.00 		Mus musculus
DRCCACACCCWN
NWGGGTGTGGYH		 Misc
Heinz et al.(2010)
Erythrocyte-Klf1_GSE20478 		0.781 0.855
Klf7
M00134_2.00 		Mus musculus
NHHMCRCCCH
DGGGYGKDDN		 PBM
Badis et al.(2009)
Klf7_0974 		0.765 0.812
luna
M03704_2.00 		Drosophila melanogaster
RCCACRCCCH
DGGGYGTGGY		 SELEX
Nitta et al.(2015)
luna_1 		0.765 0.812
luna
M06163_2.00 		Drosophila melanogaster
RRMHMCRCCC
GGGYGKDKYY		 B1H
Zhu et al.(2011)
luna_SANGER_5_FBgn0040765 		0.765 0.812
luna
M06164_2.00 		Drosophila melanogaster
DRCCMCGCCCHNNN
NNNDGGGCGKGGYH		 B1H
Zhu et al.(2011)
luna_SOLEXA_5_FBgn0040765 		0.765 0.812
KLF7
M08298_2.00 		Homo sapiens
VVCHMCGCCCH
DGGGCGKDGBB		 ChIP-seq
Schmitges et al.(2016)
O75840.MEME 		0.765 0.812
KLF6
M04400_2.00 		Homo sapiens
NVMCACRCCCH
DGGGYGTGKBN		 SELEX
Yin et al.(2017)
KLF6_eDBD_HT-SELEX 		0.765 0.797
KLF6
M08857_2.00 		Homo sapiens
BYBYVNBCYMCDCCCYBBN
NVVRGGGHGKRGVNBRVRV		 Misc
Kulakovskiy et al.(2013)
KLF6_HUMAN.H11MO.0.A 		0.765 0.797
Klf6
M08962_2.00 		Mus musculus
BYBYVNBCYMCDCCCYBBN
NVVRGGGHGKRGVNBRVRV		 Misc
Kulakovskiy et al.(2013)
KLF6_MOUSE.H11MO.0.B 		0.765 0.797
KLF6
M10113_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$CPBP_Q6 		0.765 0.797
KLF6
M04401_2.00 		Homo sapiens
NRCCACGCCCH
DGGGCGTGGYN		 SELEX
Yin et al.(2017)
KLF6_eDBD_Methyl-HT-SELEX 		0.765 0.797
Klf12
M00787_2.00 		Mus musculus
NNHMCRCCCH
DGGGYGKDNN		 PBM
Weirauch et al.(2013)
pTH0977 		0.762 0.812
Klf12
M02937_2.00 		Mus musculus
GRCCACGCCCWHHHN
NDDDWGGGCGTGGYC		 SELEX
Jolma et al.(2013)
Klf12_1 		0.762 0.812
KLF12
M04430_2.00 		Homo sapiens
DRCCACGCCCH
DGGGCGTGGYH		 SELEX
Yin et al.(2017)
KLF12_FL_HT-SELEX 		0.762 0.812
KLF12
M08299_2.00 		Homo sapiens
SBNVGCCMCGCCCHB
VDGGGCGKGGCBNVS		 ChIP-seq
Schmitges et al.(2016)
Q9Y4X4.MEME 		0.762 0.812
KLF12
M08879_2.00 		Homo sapiens
GCCCCGCCCYB
VRGGGCGGGGC		 Misc
Kulakovskiy et al.(2013)
KLF12_HUMAN.H11MO.0.C 		0.762 0.812
KLF12
M10186_2.00 		Homo sapiens
HMYACDG
CHGTRKD		 Transfac
Matys et al.(2006)
V$AP2REP_01 		0.762 0.812
KLF12
M04431_2.00 		Homo sapiens
RGSCGACGCCCN
NGGGCGTCGSCY		 SELEX
Yin et al.(2017)
KLF12_FL_Methyl-HT-SELEX_1 		0.762 0.812
KLF12
M04432_2.00 		Homo sapiens
NRCCACGCCCH
DGGGCGTGGYN		 SELEX
Yin et al.(2017)
KLF12_FL_Methyl-HT-SELEX_2 		0.762 0.812
dar1
M06171_2.00 		Drosophila melanogaster
RMCACACCCWH
DWGGGTGTGKY		 B1H
Zhu et al.(2011)
CG12029_SANGER_10_FBgn0035454 		0.758 0.768
dar1
M06172_2.00 		Drosophila melanogaster
NNNRCCACRCCCHNN
NNDGGGYGTGGYNNN		 B1H
Zhu et al.(2011)
CG12029_SOLEXA_5_FBgn0035454 		0.758 0.768
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMODP00000018197 C2H2 ZF 424 448
ENSMODP00000018197 C2H2 ZF 454 478
ENSMODP00000018197 C2H2 ZF 484 506
ENSMODP00000027792 C2H2 ZF 390 414
ENSMODP00000027792 C2H2 ZF 420 444
ENSMODP00000027792 C2H2 ZF 450 472

Links

Other C2H2 ZF family TFs
Other Monodelphis domestica TFs

669 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
AARA009355 Anopheles arabiensis AARA009355 N
ACEP19659 Atta cephalotes ACEP19659 N
ACOM031370 Anopheles coluzzii ACOM031370 N
AEPI003098 Anopheles epiroticus AEPI003098 N
AEPI009274 Anopheles epiroticus AEPI009274 N
Alligator_sinensis_CCG013371.1 Alligator sinensis Alligator_sinensis_CCG013371.1 N
AMEC017016 Anopheles melas AMEC017016 N
AMEM000352 Anopheles merus AMEM000352 N
ANCCEY_14935 Ancylostoma ceylanicum ANCCEY_14935 N
AQUA001972 Anopheles quadriannulatus AQUA001972 N
BGLB001603 Biomphalaria glabrata BGLB001603 N
Bm11731 Brugia malayi Bm11731 N
Bm12319 Brugia malayi Bm12319 N
Brh_R001625 Buceros rhinoceros Brh_R001625 N
Brh_R008554 Buceros rhinoceros Brh_R008554 N
Cflo_00615--XP_001121679.1_APIME Camponotus floridanus Cflo_00615--XP_001121679.1_APIME N
Cflo_01443--XP_624772.1_APIME Camponotus floridanus Cflo_01443--XP_624772.1_APIME N
Cflo_16445--XP_624772.1_APIME Camponotus floridanus Cflo_16445--XP_624772.1_APIME N
CLEC000374 Cimex lectularius CLEC000374 N
CLEC013286 Cimex lectularius CLEC013286 N
CPIJ012901 Culex quinquefasciatus CPIJ012901 N
CpipJ_CPIJ012901 Culex pipiens CpipJ_CPIJ012901 N
D917_05405 Trichinella nativa D917_05405 N
D917_09827 Trichinella nativa D917_09827 N
KLF6 Bos taurus ENSBTAG00000015188 N
KLF6 Callithrix jacchus ENSCJAG00000032379 I 0.765
klf4 Danio rerio ENSDARG00000079922 N
KLF1 Echinops telfairi ENSETEG00000002006 N
ENSFALG00000014565 Ficedula albicollis ENSFALG00000014565 N
KLF6 Homo sapiens ENSG00000067082 D 0.765
ENSGALG00000028383 Gallus gallus ENSGALG00000028383 N
ENSLOCG00000003791 Lepisosteus oculatus ENSLOCG00000003791 I 0.813
ENSOARG00000018838 Ovis aries ENSOARG00000018838 N
KLF12 Oryctolagus cuniculus ENSOCUG00000004244 N
ENSOPRG00000000197 Ochotona princeps ENSOPRG00000000197 N
KLF5 Ochotona princeps ENSOPRG00000007620 N
KLF3 Procavia capensis ENSPCAG00000015573 N
ENSPFOG00000015451 Poecilia formosa ENSPFOG00000015451 I 0.765
KLF1 Pteropus vampyrus ENSPVAG00000014711 N
Klf7 Rattus norvegicus ENSRNOG00000012961 N
ENSSARG00000006987 Sorex araneus ENSSARG00000006987 N
ENSSHAG00000001834 Sarcophilus harrisii ENSSHAG00000001834 N
KLF10 Tupaia belangeri ENSTBEG00000007597 N
KLF3 Tupaia belangeri ENSTBEG00000015639 N
ENSTTRG00000010639 Tursiops truncatus ENSTTRG00000010639 N
estExt_fgenesh2_pg.C_20012 Branchiostoma floridae estExt_fgenesh2_pg.C_20012 N
GA25126 Drosophila pseudoobscura FBgn0246509 N
GA28679 Drosophila pseudoobscura FBgn0250039 N
HDID_0000086901 Hymenolepis diminuta HDID_0000086901 N
HHAL000942-PA Halyomorpha halys HHAL000942-PA N
HHAL008173-PA Halyomorpha halys HHAL008173-PA N
Hsal_02965--XP_624772.1_APIME Harpegnathos saltator Hsal_02965--XP_624772.1_APIME N
ISCW004118 Ixodes scapularis ISCW004118 N
L798_04124 Zootermopsis nevadensis L798_04124 N
LDEC010928 Leptinotarsa decemlineata LDEC010928 N
LDEC024398 Leptinotarsa decemlineata LDEC024398 N
LLOJ001749 Lutzomyia longipalpis LLOJ001749 N
MESCA001789 Megaselia scalaris MESCA001789 N
nRc.2.0.1.g26965 Romanomermis culicivorax nRc.2.0.1.g26965 N
Ocbimv22007603m.g Octopus bimaculoides Ocbimv22007603m.g N
Ogr05338 Ophisaurus gracilis Ogr05338 N
PHUM399820 Pediculus humanus PHUM399820 N
PPAI010678 Phlebotomus papatasi PPAI010678 N
Pvit_06515 Pogona vitticeps Pvit_06515 N
RPRC011844 Rhodnius prolixus RPRC011844 N
Sakowv30032823m.g Saccoglossus kowalevskii Sakowv30032823m.g I
SINV23345 Solenopsis invicta SINV23345 N
SMAR000017 Strigamia maritima SMAR000017 N
SMTD_0002129001 Schistosoma mattheei SMTD_0002129001 N
SROB_0000810301 Schistosoma rodhaini SROB_0000810301 N
Tal_R002680 Tyto alba Tal_R002680 N
Tal_R005095 Tyto alba Tal_R005095 N
TC003611 Tribolium castaneum TC003611 N