Klf4 (Mus musculus)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSMUSG00000003032 T100977_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Klf4
M08021_2.00		 Mus musculus
VRCCMCRCCCH
DGGGYGKGGYB		 ChIP-seq
Chen et al.(2011)
SRP000217_Klf4		 (Direct) (Direct)
Klf4
M08964_2.00		 Mus musculus
GCCMCRCCCWBYBBN
NVVRVWGGGYGKGGC		 Misc
Kulakovskiy et al.(2013)
KLF4_MOUSE.H11MO.0.A		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
KLF4
M04463_2.00 		Homo sapiens
NVCCACRCCCH
DGGGYGTGGBN		 SELEX
Yin et al.(2017)
KLF4_eDBD_HT-SELEX 		0.827 1.000
KLF4
M08091_2.00 		Homo sapiens
MCACACCCWNN
NNWGGGTGTGK		 ChIP-seq
Mathelier et al.(2014)
MA0039.3 		0.827 1.000
KLF4
M08243_2.00 		Homo sapiens
RCCMCRCCCH
DGGGYGKGGY		 ChIP-seq
Najafabadi et al.(2015b)
KLF14 		0.827 1.000
KLF4
M08894_2.00 		Homo sapiens
RCCMCRCCCH
DGGGYGKGGY		 Misc
Kulakovskiy et al.(2013)
KLF4_HUMAN.H11MO.0.A 		0.827 1.000
KLF4
M10217_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$GKLF_02 		0.827 1.000
KLF4
M10218_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$GKLF_Q3_01 		0.827 1.000
KLF4
M10219_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$GKLF_Q3 		0.827 1.000
KLF4
M10220_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$GKLF_Q4 		0.827 1.000
KLF4
M04464_2.00 		Homo sapiens
NVCCMCRCCCN
NGGGYGKGGBN		 SELEX
Yin et al.(2017)
KLF4_eDBD_Methyl-HT-SELEX 		0.827 1.000
KLF2
M04455_2.00 		Homo sapiens
NVCCMCRCCCH
DGGGYGKGGBN		 SELEX
Yin et al.(2017)
KLF2_eDBD_HT-SELEX 		0.813 0.942
KLF2
M10210_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$LKLF_Q3 		0.813 0.942
KLF2
M10211_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$LKLF_Q6 		0.813 0.942
KLF2
M04456_2.00 		Homo sapiens
NVCCMCRCCCN
NGGGYGKGGBN		 SELEX
Yin et al.(2017)
KLF2_eDBD_Methyl-HT-SELEX 		0.813 0.942
KLF1
M00226_2.00 		Homo sapiens
CMCGCCCM
KGGGCGKG		 PBM
Barrera et al.(2016)
KLF1_REF 		0.784 0.884
KLF1
M08293_2.00 		Homo sapiens
NVNNNRCCMCRCCCH
DGGGYGKGGYNNNBN		 ChIP-seq
Schmitges et al.(2016)
Q13351.MEME 		0.784 0.884
KLF1
M08871_2.00 		Homo sapiens
SVNDGCCMCRCCCH
DGGGYGKGGCHNBS		 Misc
Kulakovskiy et al.(2013)
KLF1_HUMAN.H11MO.0.A 		0.784 0.884
KLF1
M10163_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$EKLF_Q5_01 		0.784 0.884
KLF1
M10164_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$EKLF_Q5 		0.784 0.884
KLF1
M00224_2.00 		Homo sapiens
YMCGCCCH
DGGGCGKR		 PBM
Barrera et al.(2016)
KLF1_H299Y 		0.784 0.870
KLF5
M04410_2.00 		Homo sapiens
NMCACRCCCH
DGGGYGTGKN		 SELEX
Yin et al.(2017)
KLF5_eDBD_HT-SELEX 		0.784 0.841
KLF5
M08086_2.00 		Homo sapiens
BCCMCDCCCH
DGGGHGKGGV		 ChIP-seq
Mathelier et al.(2014)
MA0599.1 		0.784 0.841
KLF5
M08868_2.00 		Homo sapiens
NHVNRCCMCDCCCH
DGGGHGKGGYNBDN		 Misc
Kulakovskiy et al.(2013)
KLF5_HUMAN.H11MO.0.A 		0.784 0.841
Klf5
M08965_2.00 		Mus musculus
KCCMCDCCCHBBBCH
DGVVVDGGGHGKGGM		 Misc
Kulakovskiy et al.(2013)
KLF5_MOUSE.H11MO.0.A 		0.784 0.841
KLF5
M09502_2.00 		Homo sapiens
GCCMCRCCCH
DGGGYGKGGC		 Misc
Heinz et al.(2010)
LoVo-KLF5_GSE49402 		0.784 0.841
KLF5
M10149_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$BTEB2_Q3_01 		0.784 0.841
KLF5
M10150_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$BTEB2_Q3 		0.784 0.841
KLF5
M04411_2.00 		Homo sapiens
NMCACRCCYH
DRGGYGTGKN		 SELEX
Yin et al.(2017)
KLF5_eDBD_Methyl-HT-SELEX 		0.784 0.841
KLF3
M04418_2.00 		Homo sapiens
RRCCRCGCCCH
DGGGCGYGGYY		 SELEX
Yin et al.(2017)
KLF3_FL_HT-SELEX 		0.784 0.826
KLF3
M08876_2.00 		Homo sapiens
NSNNVCCMCRCCCHBBBBN
NVVVVDGGGYGKGGBNNSN		 Misc
Kulakovskiy et al.(2013)
KLF3_HUMAN.H11MO.0.B 		0.784 0.826
Klf3
M08982_2.00 		Mus musculus
NSNNVCCMCRCCCHBBBBN
NVVVVDGGGYGKGGBNNSN		 Misc
Kulakovskiy et al.(2013)
KLF3_MOUSE.H11MO.0.A 		0.784 0.826
KLF3
M10172_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$KLF3_Q3_01 		0.784 0.826
KLF3
M10173_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$KLF3_Q3 		0.784 0.826
KLF3
M04419_2.00 		Homo sapiens
DRCCACGCCCH
DGGGCGTGGYH		 SELEX
Yin et al.(2017)
KLF3_FL_Methyl-HT-SELEX_1 		0.784 0.826
KLF3
M04420_2.00 		Homo sapiens
RRSCGCARCCCN
NGGGYTGCGSYY		 SELEX
Yin et al.(2017)
KLF3_FL_Methyl-HT-SELEX_2 		0.784 0.826
Klf1
M08099_2.00 		Mus musculus
NRCCACACCCW
WGGGTGTGGYN		 ChIP-seq
Mathelier et al.(2014)
MA0493.1 		0.781 0.855
Klf1
M09008_2.00 		Mus musculus
MVMNSCCMCRCCCH
DGGGYGKGGSNKBK		 Misc
Kulakovskiy et al.(2013)
KLF1_MOUSE.H11MO.0.A 		0.781 0.855
Klf1
M09516_2.00 		Mus musculus
DRCCACACCCWN
NWGGGTGTGGYH		 Misc
Heinz et al.(2010)
Erythrocyte-Klf1_GSE20478 		0.781 0.855
Klf7
M00134_2.00 		Mus musculus
NHHMCRCCCH
DGGGYGKDDN		 PBM
Badis et al.(2009)
Klf7_0974 		0.765 0.812
luna
M03704_2.00 		Drosophila melanogaster
RCCACRCCCH
DGGGYGTGGY		 SELEX
Nitta et al.(2015)
luna_1 		0.765 0.812
luna
M06163_2.00 		Drosophila melanogaster
RRMHMCRCCC
GGGYGKDKYY		 B1H
Zhu et al.(2011)
luna_SANGER_5_FBgn0040765 		0.765 0.812
luna
M06164_2.00 		Drosophila melanogaster
DRCCMCGCCCHNNN
NNNDGGGCGKGGYH		 B1H
Zhu et al.(2011)
luna_SOLEXA_5_FBgn0040765 		0.765 0.812
KLF7
M08298_2.00 		Homo sapiens
VVCHMCGCCCH
DGGGCGKDGBB		 ChIP-seq
Schmitges et al.(2016)
O75840.MEME 		0.765 0.812
KLF6
M04400_2.00 		Homo sapiens
NVMCACRCCCH
DGGGYGTGKBN		 SELEX
Yin et al.(2017)
KLF6_eDBD_HT-SELEX 		0.765 0.797
KLF6
M08857_2.00 		Homo sapiens
BYBYVNBCYMCDCCCYBBN
NVVRGGGHGKRGVNBRVRV		 Misc
Kulakovskiy et al.(2013)
KLF6_HUMAN.H11MO.0.A 		0.765 0.797
Klf6
M08962_2.00 		Mus musculus
BYBYVNBCYMCDCCCYBBN
NVVRGGGHGKRGVNBRVRV		 Misc
Kulakovskiy et al.(2013)
KLF6_MOUSE.H11MO.0.B 		0.765 0.797
KLF6
M10113_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$CPBP_Q6 		0.765 0.797
KLF6
M04401_2.00 		Homo sapiens
NRCCACGCCCH
DGGGCGTGGYN		 SELEX
Yin et al.(2017)
KLF6_eDBD_Methyl-HT-SELEX 		0.765 0.797
Klf12
M00787_2.00 		Mus musculus
NNHMCRCCCH
DGGGYGKDNN		 PBM
Weirauch et al.(2013)
pTH0977 		0.762 0.812
Klf12
M02937_2.00 		Mus musculus
GRCCACGCCCWHHHN
NDDDWGGGCGTGGYC		 SELEX
Jolma et al.(2013)
Klf12_1 		0.762 0.812
KLF12
M04430_2.00 		Homo sapiens
DRCCACGCCCH
DGGGCGTGGYH		 SELEX
Yin et al.(2017)
KLF12_FL_HT-SELEX 		0.762 0.812
KLF12
M08299_2.00 		Homo sapiens
SBNVGCCMCGCCCHB
VDGGGCGKGGCBNVS		 ChIP-seq
Schmitges et al.(2016)
Q9Y4X4.MEME 		0.762 0.812
KLF12
M08879_2.00 		Homo sapiens
GCCCCGCCCYB
VRGGGCGGGGC		 Misc
Kulakovskiy et al.(2013)
KLF12_HUMAN.H11MO.0.C 		0.762 0.812
KLF12
M10186_2.00 		Homo sapiens
HMYACDG
CHGTRKD		 Transfac
Matys et al.(2006)
V$AP2REP_01 		0.762 0.812
KLF12
M04431_2.00 		Homo sapiens
RGSCGACGCCCN
NGGGCGTCGSCY		 SELEX
Yin et al.(2017)
KLF12_FL_Methyl-HT-SELEX_1 		0.762 0.812
KLF12
M04432_2.00 		Homo sapiens
NRCCACGCCCH
DGGGCGTGGYN		 SELEX
Yin et al.(2017)
KLF12_FL_Methyl-HT-SELEX_2 		0.762 0.812
dar1
M06171_2.00 		Drosophila melanogaster
RMCACACCCWH
DWGGGTGTGKY		 B1H
Zhu et al.(2011)
CG12029_SANGER_10_FBgn0035454 		0.758 0.768
dar1
M06172_2.00 		Drosophila melanogaster
NNNRCCACRCCCHNN
NNDGGGYGTGGYNNN		 B1H
Zhu et al.(2011)
CG12029_SOLEXA_5_FBgn0035454 		0.758 0.768
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000103245 C2H2 ZF 400 424
ENSMUSP00000103245 C2H2 ZF 430 454
ENSMUSP00000103245 C2H2 ZF 460 482

Links

Other C2H2 ZF family TFs
Other Mus musculus TFs

668 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
A1O1_02576 Capronia coronata A1O1_02576 I
A1O3_05449 Capronia epimyces A1O3_05449 I
A1O5_01242 Cladophialophora psammophila A1O5_01242 I
A1O7_08736 Cladophialophora yegresii A1O7_08736 I
A1O9_12266 Exophiala aquamarina A1O9_12266 I
ACRE_013080 Acremonium chrysogenum ACRE_013080 I
AOL_s00043g74 Arthrobotrys oligospora AOL_s00043g74 I
ARB_05956 Arthroderma benhamiae ARB_05956 I
AUEXF2481DRAFT_4094 Aureobasidium subglaciale AUEXF2481DRAFT_4094 I
BAUCODRAFT_269899 Baudoinia compniacensis BAUCODRAFT_269899 I
BBA_00488 Beauveria bassiana BBA_00488 I
BDDG_07691 Blastomyces dermatitidis BDDG_07691 I
BGHDH14_bgh03757 Blumeria graminis BGHDH14_bgh03757 I
ACLA_055970 Aspergillus clavatus CADACLAG00005179 I
CADAFLAG00008024 Aspergillus flavus CADAFLAG00008024 I
AFUA_4G02940 Aspergillus fumigatus CADAFUAG00001401 I
CADANGAG00011236 Aspergillus niger CADANGAG00011236 I
ANIA_10378 Aspergillus nidulans CADANIAG00009880 D
CADAORAG00000177 Aspergillus oryzae CADAORAG00000177 I
ATEG_07901 Aspergillus terreus CADATEAG00000497 I
NFIA_030610 Neosartorya fischeri CADNFIAG00002762 I
CCM_04263 Cordyceps militaris CCM_04263 I
CFIO01_07847 Colletotrichum fioriniae CFIO01_07847 I
CGGC5_1206 Colletotrichum gloeosporioides CGGC5_1206 I
CH063_13592 Colletotrichum higginsianum CH063_13592 I
CIMG_08892 Coccidioides immitis CIMG_08892 I
CMQ_2549 Grosmannia clavigera CMQ_2549 I
Cob_10575 Colletotrichum orbiculare Cob_10575 I
COCC4DRAFT_40407 Bipolaris maydis COCC4DRAFT_40407 I
COCCADRAFT_6984 Bipolaris zeicola COCCADRAFT_6984 I
COCMIDRAFT_33369 Bipolaris oryzae COCMIDRAFT_33369 I
COCSADRAFT_97657 Bipolaris sorokiniana COCSADRAFT_97657 I
COCVIDRAFT_17332 Bipolaris victoriae COCVIDRAFT_17332 I
CPC735_064040 Coccidioides posadasii CPC735_064040 I
CPUR_06057 Claviceps purpurea CPUR_06057 I
CSUB01_02829 Colletotrichum sublineola CSUB01_02829 I
CTHT_0032650 Chaetomium thermophilum CTHT_0032650 I
DRE_06529 Drechslerella stenobrocha DRE_06529 I
EPUS_01825 Endocarpon pusillum EPUS_01825 I
estExt_fgenesh1_pg.C_400021 Mycosphaerella fijiensis estExt_fgenesh1_pg.C_400021 N
estExt_fgenesh1_pm.C_30735 Cryphonectria parasitica estExt_fgenesh1_pm.C_30735 I
EURHEDRAFT_411156 Aspergillus ruber EURHEDRAFT_411156 I
EV44_g4901 Erysiphe necator EV44_g4901 I
e_gw1.00710.230.1 Aspergillus carbonarius e_gw1.00710.230.1 I
F503_08759 Ophiostoma piceae uamh F503_08759 I
FFUJ_04663 Fusarium fujikuroi FFUJ_04663 I
fgenesh1_kg.C_scaffold_5000057 Cochliobolus heterostrophus C5 fgenesh1_kg.C_scaffold_5000057 I
fgenesh1_pg.sca_18_chr2_1_0000729 Nectria haematococca fgenesh1_pg.sca_18_chr2_1_0000729 I
FGRRES_09832 Fusarium graminearum FGRRES_09832 I
FOXG_08221 Fusarium oxysporum FOXG_08221 I
FPSE_10348 Fusarium pseudograminearum FPSE_10348 I
FVEG_06450 Fusarium verticillioides FVEG_06450 I
G647_07711 Cladophialophora carrionii G647_07711 I
GGTG_08387 Gaeumannomyces graminis GGTG_08387 I
GLRG_02817 Colletotrichum graminicola GLRG_02817 I
GSTUM_00012070001 Tuber melanosporum GSTUM_00012070001 I
H072_3248 Dactylellina haptotyla H072_3248 I
H102_02845 Trichophyton rubrum H102_02845 I
H105_02864 Trichophyton soudanense H105_02864 I
HCBG_08448 Histoplasma capsulatum HCBG_08448 I
HMPREF1120_07358 Exophiala dermatitidis HMPREF1120_07358 I
HMPREF1541_04204 Cyphellophora europaea HMPREF1541_04204 I
HMPREF1624_06072 Sporothrix schenckii HMPREF1624_06072 I
LEMA_P075830.1 Leptosphaeria maculans LEMA_P075830.1 I
M437DRAFT_18084 Aureobasidium melanogenum M437DRAFT_18084 I
M7I_6846 Glarea lozoyensis M7I_6846 I
MAC_06402 Metarhizium acridum MAC_06402 I
MAJ_07228 Metarhizium majus MAJ_07228 I
MAM_03966 Metarhizium album MAM_03966 I
MANI_020708 Metarhizium anisopliae MANI_020708 I
MBM_06253 Marssonina brunnea MBM_06253 I
MBR_00309 Metarhizium brunneum MBR_00309 I
MCYG_02695 Microsporum canis MCYG_02695 I
MCYG_02695 Arthroderma otae MCYG_02695 I
MGG_06131 Magnaporthe oryzae MGG_06131 I
MGU_01258 Metarhizium guizhouense MGU_01258 I
MGYG_08430 Microsporum gypseum MGYG_08430 I
MPH_02812 Macrophomina phaseolina MPH_02812 I
MYCFIDRAFT_89211 Pseudocercospora fijiensis MYCFIDRAFT_89211 N
MYCTH_2299061 Myceliophthora thermophila MYCTH_2299061 I
NCU06399 Neurospora crassa NCU06399 D
NechaG76538 Fusarium solani NechaG76538 I
NEUTE1DRAFT_121024 Neurospora tetrasperma NEUTE1DRAFT_121024 I
OCS_02153 Ophiocordyceps sinensis OCS_02153 I
PAAG_01597 Paracoccidioides sp lutzii PAAG_01597 I
Pc12g13890 Penicillium chrysogenum Pc12g13890 I
PCH_Pc12g13890 Penicillium rubens PCH_Pc12g13890 I
PDE_01297 Penicillium oxalicum PDE_01297 I
PDIP_77620 Penicillium digitatum PDIP_77620 I
PEX1_065040 Penicillium expansum PEX1_065040 I
PFICI_05721 Pestalotiopsis fici PFICI_05721 I
PITC_048290 Penicillium italicum PITC_048290 I
PMAA_006130 Talaromyces marneffei PMAA_006130 I
PMAA_006130 Penicillium marneffei PMAA_006130 I
PODANS_3_4790 Podospora anserina PODANS_3_4790 I
PTRG_08316 Pyrenophora triticirepentis PTRG_08316 I
PTT_12277 Pyrenophora teres PTT_12277 I
PV04_09319 Capronia semiimmersa PV04_09319 I
PV05_00805 Exophiala xenobiotica PV05_00805 I
PV06_05138 Exophiala oligosperma PV06_05138 I
PV07_00488 Cladophialophora immunda PV07_00488 I
PV08_09059 Exophiala spinifera PV08_09059 I
PV09_01316 Verruconis gallopava PV09_01316 I
PV10_04959 Exophiala mesophila PV10_04959 I
PV11_02396 Exophiala sideris PV11_02396 I
S40285_06955 Stachybotrys chlorohalonata S40285_06955 I
S40288_05306 Stachybotrys chartarum S40288_05306 I
SAPIO_CDS7180 Scedosporium apiospermum SAPIO_CDS7180 I
scaffold_3-snap.528.1 Neurospora discreta scaffold_3-snap.528.1 I
SEPMUDRAFT_150066 Sphaerulina musiva SEPMUDRAFT_150066 I
SETTUDRAFT_96438 Setosphaeria turcica SETTUDRAFT_96438 I
SNOG_08036 Stagonospora nodorum SNOG_08036 I
SNOG_08036 Phaeosphaeria nodorum SNOG_08036 I
SPBR_00166 Sporothrix brasiliensis SPBR_00166 I
SS1G_13065 Sclerotinia sclerotiorum SS1G_13065 I
THITE_2115495 Thielavia terrestris THITE_2115495 I
TRIATDRAFT_168746 Trichoderma atroviride TRIATDRAFT_168746 I
TRIREDRAFT_41573 Trichoderma reesei TRIREDRAFT_41573 I
TRIVIDRAFT_192202 Trichoderma virens TRIVIDRAFT_192202 I
TRV_07458 Trichophyton verrucosum TRV_07458 I
TSTA_104870 Talaromyces stipitatus TSTA_104870 I
U727_0043258041 Penicillium solitum U727_0043258041 I
UCRNP2_2391 Neofusicoccum parvum UCRNP2_2391 I
UREG_02800 Uncinocarpus reesii UREG_02800 I
UV8b_314 Ustilaginoidea virens UV8b_314 I
VDAG_08933 Verticillium dahliae VDAG_08933 I
VHEMI03455 Torrubiella hemipterigena VHEMI03455 I
W97_04573 Coniosporium apollinis W97_04573 I
X797_002671 Metarhizium robertsii X797_002671 I
Z517_01506 Fonsecaea pedrosoi Z517_01506 I
Z518_05180 Rhinocladiella mackenziei Z518_05180 I
Z519_08509 Cladophialophora bantiana Z519_08509 I