GRHL1 (Homo sapiens)
Grainyhead

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF04516 (CP2) IPR007604 ENSG00000134317 T199007_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
GRHL1
M03071_2.00		 Homo sapiens
RACYKGWHNDWCMGGTT
AACCKGWHNDWCMRGTY		 SELEX
Jolma et al.(2013)
GRHL1_1		 (Direct) (Direct)
GRHL1
M03072_2.00		 Homo sapiens
DAACCGGTTH
DAACCGGTTH		 SELEX
Jolma et al.(2013)
GRHL1_2		 (Direct) (Direct)
GRHL1
M03073_2.00		 Homo sapiens
HWAACCGGTTTD
HAAACCGGTTWD		 SELEX
Jolma et al.(2013)
GRHL1_3		 (Direct) (Direct)
GRHL1
M04887_2.00		 Homo sapiens
DAACCGGTTH
DAACCGGTTH		 SELEX
Yin et al.(2017)
GRHL1_eDBD_HT-SELEX		 (Direct) (Direct)
GRHL1
M04888_2.00		 Homo sapiens
DAACMKGTTH
DAACMKGTTH		 SELEX
Yin et al.(2017)
GRHL1_eDBD_Methyl-HT-SELEX		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
GRHL2
M08129_2.00 		Homo sapiens
NNNAACTGGTTTNNN
NNNAAACCAGTTNNN		 ChIP-seq
Mathelier et al.(2014)
MA1105.1 		0.723 0.723
GRHL2
M09125_2.00 		Homo sapiens
AACYDGYYBDDC
GHHVRRCHRGTT		 Misc
Kulakovskiy et al.(2013)
GRHL2_HUMAN.H11MO.0.A 		0.723 0.723
Grhl2
M09126_2.00 		Mus musculus
RDCCDGTYYKDC
GHMRRACHGGHY		 Misc
Kulakovskiy et al.(2013)
GRHL2_MOUSE.H11MO.0.A 		0.723 0.723
GRHL2
M09558_2.00 		Homo sapiens
NRAACHDGHHDDDCHDGTTY
RAACHDGHHHDDCHDGTTYN		 Misc
Heinz et al.(2010)
HBE-GRHL2_GSE46194 		0.723 0.723
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000324693 Grainyhead 230 442
ENSP00000384209 Grainyhead 34 253
ENSP00000418275 Grainyhead 230 442

Links

Other Grainyhead family TFs
Other Homo sapiens TFs

109 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
AB00152.1 Alternaria brassicicola AB00152.1 N
ARB_04480 Arthroderma benhamiae ARB_04480 N
BDDG_01953 Blastomyces dermatitidis BDDG_01953 N
CCM_09117 Cordyceps militaris CCM_09117 N
CH063_11689 Colletotrichum higginsianum CH063_11689 N
CHGG_05369 Chaetomium globosum CHGG_05369 N
Cob_05476 Colletotrichum orbiculare Cob_05476 N
COCC4DRAFT_156026 Bipolaris maydis COCC4DRAFT_156026 N
COCSADRAFT_213113 Bipolaris sorokiniana COCSADRAFT_213113 N
CTHT_0072490 Chaetomium thermophilum CTHT_0072490 N
estExt_Genewise1.C_170090 Neurospora discreta estExt_Genewise1.C_170090 N
H101_07016 Trichophyton interdigitale H101_07016 N
HCBG_00501 Histoplasma capsulatum HCBG_00501 N
LEMA_P068960.1 Leptosphaeria maculans LEMA_P068960.1 N
MCYG_05885 Arthroderma otae MCYG_05885 N
MCYG_05885 Microsporum canis MCYG_05885 N
MGYG_06086 Microsporum gypseum MGYG_06086 N
MYCTH_2061546 Myceliophthora thermophila MYCTH_2061546 N
NCU05681 Neurospora crassa NCU05681 N
NEUTE1DRAFT_80790 Neurospora tetrasperma NEUTE1DRAFT_80790 N
PAAG_06800 Paracoccidioides sp lutzii PAAG_06800 N
PABG_01084 Paracoccidioides brasiliensis PABG_01084 N
PFICI_12751 Pestalotiopsis fici PFICI_12751 N
PMAA_055610 Penicillium marneffei PMAA_055610 N
PMAA_055610 Talaromyces marneffei PMAA_055610 N
PODANS_7_650 Podospora anserina PODANS_7_650 N
PTRG_10690 Pyrenophora triticirepentis PTRG_10690 N
PTT_05695 Pyrenophora teres PTT_05695 N
PVAR5_1962 Byssochlamys spectabilis PVAR5_1962 N
SAPIO_CDS2052 Scedosporium apiospermum SAPIO_CDS2052 N
SETTUDRAFT_153515 Setosphaeria turcica SETTUDRAFT_153515 N
SMAC_02038 Sordaria macrospora SMAC_02038 N
SNOG_09796 Stagonospora nodorum SNOG_09796 N
TEQG_06359 Trichophyton equinum TEQG_06359 N
TESG_07518 Trichophyton tonsurans TESG_07518 N
TRIATDRAFT_299214 Trichoderma atroviride TRIATDRAFT_299214 N
TRIREDRAFT_58853 Trichoderma reesei TRIREDRAFT_58853 N
TSTA_016750 Talaromyces stipitatus TSTA_016750 N
V499_03776 Pseudogymnoascus pannorum V499_03776 N