NKX2-6 (Monodelphis domestica)
Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox) IPR001356 ENSMODG00000016788 T212171_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Nkx2-3
M00497_2.00 		Mus musculus
NNRAGDRNN
NNYHCTYNN		 PBM
Berger et al.(2008)
Nkx2-3_3435 		0.852 0.912
NKX2-3
M05042_2.00 		Homo sapiens
NNBAAGTGBN
NVCACTTVNN		 SELEX
Yin et al.(2017)
NKX2-3_eDBD_HT-SELEX 		0.852 0.912
NKX2-3
M05045_2.00 		Homo sapiens
BNBAAGTGBN
NVCACTTVNV		 SELEX
Yin et al.(2017)
NKX2-3_FL_HT-SELEX 		0.852 0.912
NKX2-3
M05043_2.00 		Homo sapiens
BNBAAGTGBN
NVCACTTVNV		 SELEX
Yin et al.(2017)
NKX2-3_eDBD_Methyl-HT-SELEX_1 		0.852 0.912
NKX2-3
M05044_2.00 		Homo sapiens
SDYAACGHB
VDCGTTRHS		 SELEX
Yin et al.(2017)
NKX2-3_eDBD_Methyl-HT-SELEX_2 		0.852 0.912
NKX2-3
M05046_2.00 		Homo sapiens
BNBAAGTGBN
NVCACTTVNV		 SELEX
Yin et al.(2017)
NKX2-3_FL_Methyl-HT-SELEX_1 		0.852 0.912
NKX2-3
M05047_2.00 		Homo sapiens
SWYAACSHB
VDSGTTRWS		 SELEX
Yin et al.(2017)
NKX2-3_FL_Methyl-HT-SELEX_2 		0.852 0.912
NKX2-5
M00323_2.00 		Homo sapiens
NWYAAGTGSNN
NNSCACTTRWN		 PBM
Barrera et al.(2016)
NKX2-5_REF 		0.850 0.860
Nkx2-5
M00404_2.00 		Mus musculus
NNNRAGDRBN
NVYHCTYNNN		 PBM
Berger et al.(2008)
Nkx2-5_3436 		0.850 0.860
NKX2-5
M05346_2.00 		Homo sapiens
BHYAAGTGBN
NVCACTTRDV		 SELEX
Yin et al.(2017)
NKX2-5_FL_HT-SELEX 		0.850 0.860
Nkx2-5
M02686_2.00 		Mus musculus
WTAAKWK
MWMTTAW		 SELEX
Mathelier et al.(2014)
MA0063.1 		0.850 0.860
Nkx2-5
M08136_2.00 		Mus musculus
SYTGAGWGSYH
DRSCWCTCARS		 ChIP-seq
Mathelier et al.(2014)
MA0503.1 		0.850 0.860
NKX2-5
M09163_2.00 		Homo sapiens
BKRAGWGV
BCWCTYMV		 Misc
Kulakovskiy et al.(2013)
NKX25_HUMAN.H11MO.0.B 		0.850 0.860
Nkx2-5
M09177_2.00 		Mus musculus
NBYBRAGTGS
SCACTYVRVN		 Misc
Kulakovskiy et al.(2013)
NKX25_MOUSE.H11MO.0.A 		0.850 0.860
Nkx2-5
M09567_2.00 		Mus musculus
HBRAGWGBNN
NNVCWCTYVD		 Misc
Heinz et al.(2010)
HL1-Nkx2.5.biotin_GSE21529 		0.850 0.860
NKX2-5
M10742_2.00 		Homo sapiens
TYAAGTG
CACTTRA		 Transfac
Matys et al.(2006)
V$NKX25_01 		0.850 0.860
NKX2-5
M10743_2.00 		Homo sapiens
CWTAATTV
BAATTAWG		 Transfac
Matys et al.(2006)
V$NKX25_02 		0.850 0.860
NKX2-5
M10744_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NKX25_Q5 		0.850 0.860
NKX2-5
M10745_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NKX25_Q6 		0.850 0.860
NKX2-5
M05347_2.00 		Homo sapiens
BTYAAGTGGN
NCCACTTRAV		 SELEX
Yin et al.(2017)
NKX2-5_FL_Methyl-HT-SELEX_1 		0.850 0.860
NKX2-5
M05348_2.00 		Homo sapiens
BTYAACGAB
VTCGTTRAV		 SELEX
Yin et al.(2017)
NKX2-5_FL_Methyl-HT-SELEX_2 		0.850 0.860
NKX2-5
M00322_2.00 		Homo sapiens
NNNRNNN
NNNYNNN		 PBM
Barrera et al.(2016)
NKX2-5_R190C 		0.850 0.842
NKX2-5
M00324_2.00 		Homo sapiens
NHNNNNN
NNNNNDN		 PBM
Barrera et al.(2016)
NKX2-5_T178M 		0.850 0.842
NKX2-5
M00321_2.00 		Homo sapiens
HNAAGTRBNN
NNVYACTTND		 PBM
Barrera et al.(2016)
NKX2-5_R161P 		0.846 0.842
ceh-28
M08210_2.00 		Caenorhabditis elegans
AATCGATW
WATCGATT		 ChIP-seq
Contrino et al.(2012)
Mw138 		0.825 0.754
Nkx2-6
M00496_2.00 		Mus musculus
HYAAGTRBNN
NNVYACTTRD		 PBM
Berger et al.(2008)
Nkx2-6_3437 		0.818 0.842
NKX2-5
M00320_2.00 		Homo sapiens
NHBAAKWRN
NYWMTTVDN		 PBM
Barrera et al.(2016)
NKX2-5_K183E 		0.817 0.842
scro
M03854_2.00 		Drosophila melanogaster
NNBRMGTGB
VCACKYVNN		 SELEX
Nitta et al.(2015)
scro_1 		0.805 0.807
ceh-24
M02181_2.00 		Caenorhabditis elegans
NNRAKWRNN
NNYWMTYNN		 PBM
Weirauch et al.(2014)
pTH6327 		0.801 0.754
tin
M00559_2.00 		Drosophila melanogaster
NWYAAGTGGNN
NNCCACTTRWN		 PBM
Busser et al.(2012a)
Tin 		0.791 0.702
tin
M03809_2.00 		Drosophila melanogaster
BTYAAGTGSN
NSCACTTRAV		 SELEX
Nitta et al.(2015)
tin_1 		0.791 0.702
tin
M06284_2.00 		Drosophila melanogaster
BTYAAGTG
CACTTRAV		 B1H
Zhu et al.(2011)
Tin_Cell_FBgn0004110 		0.791 0.702
tin
M06285_2.00 		Drosophila melanogaster
BCTCAAGTGSVN
NBSCACTTGAGV		 B1H
Zhu et al.(2011)
tin_FlyReg_FBgn0004110 		0.791 0.702
tin
M06286_2.00 		Drosophila melanogaster
BWYAAGTR
YACTTRWV		 B1H
Zhu et al.(2011)
Tin_SOLEXA_FBgn0004110 		0.791 0.702
tin
M08421_2.00 		Drosophila melanogaster
DBTCRAGTGS
SCACTYGAVH		 ChIP-chip
Mathelier et al.(2014)
MA0247.2 		0.791 0.702
Nkx2-1
M00385_2.00 		Mus musculus
NNRAGDRN
NYHCTYNN		 PBM
Berger et al.(2008)
Titf1_1722 		0.784 0.789
Nkx2-4
M00514_2.00 		Mus musculus
NNRAGDRBNN
NNVYHCTYNN		 PBM
Berger et al.(2008)
Nkx2-4_3074 		0.784 0.789
NKX2-1
M09146_2.00 		Homo sapiens
BTKGAGWGBN
NVCWCTCMAV		 Misc
Kulakovskiy et al.(2013)
NKX21_HUMAN.H11MO.0.A 		0.784 0.789
Nkx2-1
M09171_2.00 		Mus musculus
NBTKGAGWGB
VCWCTCMAVN		 Misc
Kulakovskiy et al.(2013)
NKX21_MOUSE.H11MO.0.A 		0.784 0.789
Nkx2-1
M09563_2.00 		Mus musculus
BTBRAGWGBH
DVCWCTYVAV		 Misc
Heinz et al.(2010)
LungAC-Nkx2.1_GSE43252 		0.784 0.789
NKX2-1
M10694_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TITF1_Q3 		0.784 0.789
NKX2-1
M10695_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TTF1_Q5_01 		0.784 0.789
NKX2-1
M10696_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TTF1_Q5 		0.784 0.789
NKX2-1
M10697_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TTF1_Q6 		0.784 0.789
Nkx2-9
M00520_2.00 		Mus musculus
NNNRAGDRBN
NVYHCTYNNN		 PBM
Berger et al.(2008)
Nkx2-9_3082 		0.747 0.807
Nkx2-9
M00800_2.00 		Mus musculus
NNRAGDRBNN
NNVYHCTYNN		 PBM
Weirauch et al.(2013)
pTH2842 		0.747 0.807
Nkx2-9
M09215_2.00 		Mus musculus
BTCAAGKRB
VYMCTTGAV		 Misc
Kulakovskiy et al.(2013)
NKX28_MOUSE.H11MO.0.C 		0.747 0.807
Nkx2-2
M00438_2.00 		Mus musculus
NNNRAGDRN
NYHCTYNNN		 PBM
Berger et al.(2008)
Nkx2-2_2823 		0.741 0.789
Nkx2-2
M09190_2.00 		Mus musculus
NTBRAGWGBBN
NVVCWCTYVAN		 Misc
Kulakovskiy et al.(2013)
NKX22_MOUSE.H11MO.0.A 		0.741 0.789
NKX2-2
M10681_2.00 		Homo sapiens
WTAAGTRBTT
AAVYACTTAW		 Transfac
Matys et al.(2006)
V$NKX22_01 		0.741 0.789
NKX2-2
M10682_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NKX2B_Q3_01 		0.741 0.789
NKX2-2
M10683_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NKX2B_Q3 		0.741 0.789
vnd
M06551_2.00 		Drosophila melanogaster
WYTCAAGTR
YACTTGARW		 B1H
Mathelier et al.(2014)
MA0253.1 		0.741 0.772
vnd
M06377_2.00 		Drosophila melanogaster
WYTCAAGTR
YACTTGARW		 B1H
Zhu et al.(2011)
Vnd_Cell_FBgn0003986 		0.741 0.772
vnd
M06378_2.00 		Drosophila melanogaster
KYTSAAGWGY
RCWCTTSARM		 B1H
Zhu et al.(2011)
vnd_FlyReg_FBgn0003986 		0.741 0.772
vnd
M06379_2.00 		Drosophila melanogaster
BTBAAGTR
YACTTVAV		 B1H
Zhu et al.(2011)
Vnd_SOLEXA_FBgn0003986 		0.741 0.772
vnd
M09683_2.00 		Drosophila melanogaster
TCAAGTGB
VCACTTGA		 Misc
Kulakovskiy et al.(2009)
vnd 		0.741 0.772
NKX2-8
M00302_2.00 		Homo sapiens
NNRAGDRB
VYHCTYNN		 PBM
Barrera et al.(2016)
NKX2-8_REF 		0.716 0.772
NKX2-8
M05149_2.00 		Homo sapiens
BTSRAGTGBN
NVCACTYSAV		 SELEX
Yin et al.(2017)
NKX2-8_FL_HT-SELEX 		0.716 0.772
NKX2-8
M09145_2.00 		Homo sapiens
BTCAAGKRB
VYMCTTGAV		 Misc
Kulakovskiy et al.(2013)
NKX28_HUMAN.H11MO.0.C 		0.716 0.772
NKX2-8
M00301_2.00 		Homo sapiens
NNRAKDRB
VYHMTYNN		 PBM
Barrera et al.(2016)
NKX2-8_A94T 		0.716 0.772
NKX2-8
M05150_2.00 		Homo sapiens
GCARTAACGACATC
GATGTCGTTAYTGC		 SELEX
Yin et al.(2017)
NKX2-8_FL_Methyl-HT-SELEX_1 		0.716 0.772
NKX2-8
M05151_2.00 		Homo sapiens
BTSAAGTGBN
NVCACTTSAV		 SELEX
Yin et al.(2017)
NKX2-8_FL_Methyl-HT-SELEX_2 		0.716 0.772
NKX2-8
M05152_2.00 		Homo sapiens
BTBAACGAB
VTCGTTVAV		 SELEX
Yin et al.(2017)
NKX2-8_FL_Methyl-HT-SELEX_3 		0.716 0.772
ceh-22
M00376_2.00 		Caenorhabditis elegans
WBRAGTRBNN
NNVYACTYVW		 PBM
Berger et al.(2006)
Ceh-22 		0.710 0.702
Q24782_9CNID
M02206_2.00 		Eleutheria dichotoma
TTAATTAA
TTAATTAA		 PBM
Weirauch et al.(2014)
pTH5486 		0.622 0.526
CDX1
M10761_2.00 		Gallus gallus
BDBWAAK
MTTWVHV		 Transfac
Matys et al.(2006)
V$CDXA_01 		0.604 0.474
CDX1
M10762_2.00 		Gallus gallus
WWWWMYR
YRKWAWW		 Transfac
Matys et al.(2006)
V$CDXA_02 		0.604 0.474
For this family, TFs with SR scores > 0.599 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMODP00000020954 Homeodomain 99 155

Links

Other Homeodomain family TFs
Other Monodelphis domestica TFs

853 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
BGIOSGA009571 Oryza indica BGIOSGA009571 I
Bo4g009400 Brassica oleracea Bo4g009400 I
Bo8g118250 Brassica oleracea Bo8g118250 I
Bra004548 Brassica rapa Bra004548 I
Bra032665 Brassica rapa Bra032665 I
BRADI2G07357 Brachypodium distachyon BRADI2G07357 I
BRADI2G31480 Brachypodium distachyon BRADI2G31480 I
Carubv10028227m.g Capsella rubella Carubv10028227m.g I
Ciclev10002183m.g Citrus clementina Ciclev10002183m.g I
Cla021505 Citrullus lanatus Cla021505 I
Cucsa.201950 Cucumis sativus Cucsa.201950 I
Cucsa.258900 Cucumis sativus Cucsa.258900 I
F775_13439 Aegilops tauschii F775_13439 I
GRMZM2G044077 Zea mays GRMZM2G044077 I
GRMZM2G142179 Zea mays GRMZM2G142179 I
GRMZM2G171569 Zea mays GRMZM2G171569 I
GRMZM2G328197 Zea mays GRMZM2G328197 I
GRMZM2G429378 Zea mays GRMZM2G429378 I
GSMUA_Achr10G01110_001 Musa acuminata GSMUA_Achr10G01110_001 I
GSMUA_Achr10G14570_001 Musa acuminata GSMUA_Achr10G14570_001 I
GSMUA_Achr11G19880_001 Musa acuminata GSMUA_Achr11G19880_001 I
GSMUA_Achr4G16600_001 Musa acuminata GSMUA_Achr4G16600_001 I
GSMUA_Achr5G27850_001 Musa acuminata GSMUA_Achr5G27850_001 I
GSMUA_Achr6G14240_001 Musa acuminata GSMUA_Achr6G14240_001 I
GSMUA_Achr7G21980_001 Musa acuminata GSMUA_Achr7G21980_001 I
GSMUA_Achr8G01690_001 Musa acuminata GSMUA_Achr8G01690_001 I
GSMUA_Achr9G28840_001 Musa acuminata GSMUA_Achr9G28840_001 I
LPERR01G07340 Leersia perrieri LPERR01G07340 I
LPERR03G32900 Leersia perrieri LPERR03G32900 I
Lus10005281.g Linum usitatissimum Lus10005281.g I
Lus10013958.g Linum usitatissimum Lus10013958.g I
MDP0000190504 Malus domestica MDP0000190504 I
MLOC_40486 Hordeum vulgare MLOC_40486 I
MLOC_58641 Hordeum vulgare MLOC_58641 I
OBART03G38710 Oryza barthii OBART03G38710 I
OGLUM01G08910 Oryza glumaepatula OGLUM01G08910 I
OGLUM03G38530 Oryza glumaepatula OGLUM03G38530 I
OMERI01G07770 Oryza meridionalis OMERI01G07770 I
OMERI03G35630 Oryza meridionalis OMERI03G35630 I
ONIVA01G10020 Oryza nivara ONIVA01G10020 I
ONIVA03G40360 Oryza nivara ONIVA03G40360 I
OPUNC01G07600 Oryza punctata OPUNC01G07600 I
OPUNC03G35790 Oryza punctata OPUNC03G35790 I
orange1.1g043400m.g Citrus sinensis orange1.1g043400m.g I
ORGLA01G0069400 Oryza glaberrima ORGLA01G0069400 I
ORGLA03G0354400 Oryza glaberrima ORGLA03G0354400 I
ORUFI01G08530 Oryza rufipogon ORUFI01G08530 I
ORUFI03G40350 Oryza rufipogon ORUFI03G40350 I
OS01G0224100 Oryza sativa OS01G0224100 I
OS03G0815800 Oryza sativa OS03G0815800 I
Pavir.Da00220 Panicum virgatum Pavir.Da00220 I
Pavir.Db02131 Panicum virgatum Pavir.Db02131 I
Pavir.Ea00119 Panicum virgatum Pavir.Ea00119 I
Pavir.Eb00092 Panicum virgatum Pavir.Eb00092 I
Pavir.Fa01728 Panicum virgatum Pavir.Fa01728 I
Pavir.Fb00951 Panicum virgatum Pavir.Fb00951 I
Pavir.J11205 Panicum virgatum Pavir.J11205 I
Pavir.J13096 Panicum virgatum Pavir.J13096 I
Pavir.J24236 Panicum virgatum Pavir.J24236 I
Pavir.J26710 Panicum virgatum Pavir.J26710 I
Pavir.J29117 Panicum virgatum Pavir.J29117 I
Sb02g006780 Sorghum bicolor Sb02g006780 I
Sb03g001296 Sorghum bicolor Sb03g001296 I
Sb05g001280 Sorghum bicolor Sb05g001280 I
Si002247m.g Setaria italica Si002247m.g I
TRAES3BF017100030CFD_g Triticum aestivum TRAES3BF017100030CFD_g I
TRIUR3_07811 Triticum urartu TRIUR3_07811 I