CIS-BP Database: Catalog of Inferred Sequence Binding Preferences

TF Information

Afo_R001341 *(Aptenodytes forsteri)* Homeodomain
Pfam ID	Interpro ID	Gene ID	CIS-BP ID	Sequence source
PF00046 (Homeobox)	IPR001356	Afo_R001341	T225037_2.00	GigaDB (2015-Oct-22)
Directly determined binding motifs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
No direct experiments
Motifs from related TFs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
Pknox2 M00468_2.00	Mus musculus	NNNGACRNNN	NNNYGTCNNN	PBM Berger et al.(2008) Pknox2_3077	0.867	1.000
PKNOX2 M03195_2.00	Homo sapiens	TGACAGSTGTCA	TGACASCTGTCA	SELEX Jolma et al.(2013) PKNOX2_1	0.867	1.000
Pknox2 M03270_2.00	Mus musculus	TGACAGSTGTCA	TGACASCTGTCA	SELEX Jolma et al.(2013) Pknox2_1	0.867	1.000
PKNOX2 M05246_2.00	Homo sapiens	TGACABVTGTCA	TGACABVTGTCA	SELEX Yin et al.(2017) PKNOX2_eDBD_HT-SELEX	0.867	1.000
PKNOX2 M05247_2.00	Homo sapiens	TGACASSTGTCA	TGACASSTGTCA	SELEX Yin et al.(2017) PKNOX2_eDBD_Methyl-HT-SELEX	0.867	1.000
Pknox1 M00399_2.00	Mus musculus	HGACRNNN	NNNYGTCD	PBM Berger et al.(2008) Pknox1_2364	0.867	0.964
PKNOX1 M03178_2.00	Homo sapiens	TGACAGSTGTCA	TGACASCTGTCA	SELEX Jolma et al.(2013) PKNOX1_1	0.867	0.964
PKNOX1 M05206_2.00	Homo sapiens	TGACASSTGTCA	TGACASSTGTCA	SELEX Yin et al.(2017) PKNOX1_eDBD_HT-SELEX	0.867	0.964
PKNOX1 M05208_2.00	Homo sapiens	TGACAGCTGTCA	TGACAGCTGTCA	SELEX Yin et al.(2017) PKNOX1_FL_HT-SELEX	0.867	0.964
PKNOX1 M09150_2.00	Homo sapiens	TGABTGRCRGV	BCYGYCAVTCA	Misc Kulakovskiy et al.(2013) PKNX1_HUMAN.H11MO.0.B	0.867	0.964
Pknox1 M09175_2.00	Mus musculus	TGABTGRCRGV	BCYGYCAVTCA	Misc Kulakovskiy et al.(2013) PKNX1_MOUSE.H11MO.0.A	0.867	0.964
PKNOX1 M10712_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$PREP1_Q3	0.867	0.964
PKNOX1 M05207_2.00	Homo sapiens	YGWCASSTGWCR	YGWCASSTGWCR	SELEX Yin et al.(2017) PKNOX1_eDBD_Methyl-HT-SELEX	0.867	0.964
PKNOX1 M05209_2.00	Homo sapiens	TGACABVTGTCA	TGACABVTGTCA	SELEX Yin et al.(2017) PKNOX1_FL_Methyl-HT-SELEX	0.867	0.964
Meis1 M00407_2.00	Mus musculus	NTGACADNN	NNHTGTCAN	PBM Berger et al.(2008) Meis1_2335	0.751	0.727
Meis2 M00437_2.00	Mus musculus	NTGACANNN	NNNTGTCAN	PBM Berger et al.(2008) Mrg1_2246	0.751	0.727
Meis3 M00488_2.00	Mus musculus	NTGACANNN	NNNTGTCAN	PBM Berger et al.(2008) Mrg2_2302	0.751	0.727
MEIS1 M03165_2.00	Homo sapiens	NTGACAN	NTGTCAN	SELEX Jolma et al.(2013) MEIS1_1	0.751	0.727
MEIS2 M03147_2.00	Homo sapiens	WTGACAGSTGTCAM	KTGACASCTGTCAW	SELEX Jolma et al.(2013) MEIS2_1	0.751	0.727
MEIS2 M03148_2.00	Homo sapiens	DTGACAGS	SCTGTCAH	SELEX Jolma et al.(2013) MEIS2_2	0.751	0.727
Meis2 M03261_2.00	Mus musculus	NTGACAN	NTGTCAN	SELEX Jolma et al.(2013) Meis2_1	0.751	0.727
Meis2 M03262_2.00	Mus musculus	TGACAGSTGTCA	TGACASCTGTCA	SELEX Jolma et al.(2013) Meis2_2	0.751	0.727
Meis3 M03279_2.00	Mus musculus	NTGACAN	NTGTCAN	SELEX Jolma et al.(2013) Meis3_1	0.751	0.727
Meis3 M03280_2.00	Mus musculus	TGACAGSTGTCA	TGACASCTGTCA	SELEX Jolma et al.(2013) Meis3_2	0.751	0.727
MEIS2 M02740_2.00	Homo sapiens	TGACASSTGTC	GACASSTGTCA	SELEX Jolma et al.(2010) MEIS2_dimer	0.751	0.727
MEIS2 M02741_2.00	Homo sapiens	GGACAKNT	ANMTGTCC	SELEX Jolma et al.(2010) MEIS2_monomer	0.751	0.727
MEIS2 M05138_2.00	Homo sapiens	TGACASSTGTCA	TGACASSTGTCA	SELEX Yin et al.(2017) MEIS2_eDBD_HT-SELEX	0.751	0.727
MEIS2 M05140_2.00	Homo sapiens	TGACASSTGTCA	TGACASSTGTCA	SELEX Yin et al.(2017) MEIS2_FL_HT-SELEX	0.751	0.727
hth M06490_2.00	Drosophila melanogaster	TGACAK	MTGTCA	B1H Mathelier et al.(2014) MA0227.1	0.751	0.727
hth M06252_2.00	Drosophila melanogaster	TGTCA	TGACA	B1H Zhu et al.(2011) Hth_Cell_FBgn0001235	0.751	0.727
hth M06253_2.00	Drosophila melanogaster	NNTGACAD	HTGTCANN	B1H Zhu et al.(2011) hth_SOLEXA_2_FBgn0001235	0.751	0.727
hth M06254_2.00	Drosophila melanogaster	NTGACA	TGTCAN	B1H Zhu et al.(2011) Hth_SOLEXA_FBgn0001235	0.751	0.727
MEIS1 M09148_2.00	Homo sapiens	NTGATTDATDDB	VHHATHAATCAN	Misc Kulakovskiy et al.(2013) MEIS1_HUMAN.H11MO.0.A	0.751	0.727
MEIS2 M09143_2.00	Homo sapiens	HTGACAGBTKTBM	KVAMAVCTGTCAD	Misc Kulakovskiy et al.(2013) MEIS2_HUMAN.H11MO.0.B	0.751	0.727
Meis1 M09178_2.00	Mus musculus	NTGATTDATDDB	VHHATHAATCAN	Misc Kulakovskiy et al.(2013) MEIS1_MOUSE.H11MO.0.A	0.751	0.727
Meis2 M09189_2.00	Mus musculus	HTGACAGBTKTBM	KVAMAVCTGTCAD	Misc Kulakovskiy et al.(2013) MEIS2_MOUSE.H11MO.0.B	0.751	0.727
Meis1 M09568_2.00	Mus musculus	VBTGWCASNN	NNSTGWCAVB	Misc Heinz et al.(2010) MastCells-Meis1_GSE48085	0.751	0.727
MEIS1 M10709_2.00	Homo sapiens	NHNTGACAGNDN	NHNCTGTCANDN	Transfac Matys et al.(2006) V$MEIS1_01	0.751	0.727
MEIS1 M10710_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$MEIS1_06	0.751	0.727
MEIS2 M05139_2.00	Homo sapiens	YGACASSYGHCR	YGDCRSSTGTCR	SELEX Yin et al.(2017) MEIS2_eDBD_Methyl-HT-SELEX	0.751	0.727
MEIS2 M05141_2.00	Homo sapiens	TGACASSTGTCA	TGACASSTGTCA	SELEX Yin et al.(2017) MEIS2_FL_Methyl-HT-SELEX	0.751	0.727
unc-62 M02185_2.00	Caenorhabditis elegans	NHDAHANNN	NNNTDTHDN	PBM Weirauch et al.(2014) pTH5781	0.738	0.655
Tgif2 M00521_2.00	Mus musculus	NNTGACANNN	NNNTGTCANN	PBM Berger et al.(2008) Tgif2_3451	0.633	0.527
TGIF2 M03123_2.00	Homo sapiens	TGACAGSTGTCA	TGACASCTGTCA	SELEX Jolma et al.(2013) TGIF2_1	0.633	0.527
TGIF2 M05032_2.00	Homo sapiens	TGACABVTGTCA	TGACABVTGTCA	SELEX Yin et al.(2017) TGIF2_eDBD_HT-SELEX	0.633	0.527
TGIF2 M05034_2.00	Homo sapiens	DTGACANN	NNTGTCAH	SELEX Yin et al.(2017) TGIF2_FL_HT-SELEX	0.633	0.527
TGIF2 M05033_2.00	Homo sapiens	TGWCABVTGWCA	TGWCABVTGWCA	SELEX Yin et al.(2017) TGIF2_eDBD_Methyl-HT-SELEX	0.633	0.527
TGIF2 M05035_2.00	Homo sapiens	DTGACANN	NNTGTCAH	SELEX Yin et al.(2017) TGIF2_FL_Methyl-HT-SELEX	0.633	0.527
Tgif1 M00500_2.00	Mus musculus	NNTGACANNN	NNNTGTCANN	PBM Berger et al.(2008) Tgif1_2342	0.631	0.527
TGIF1 M03223_2.00	Homo sapiens	TGACAGCTGTCA	TGACAGCTGTCA	SELEX Jolma et al.(2013) TGIF1_1	0.631	0.527
TGIF1 M05317_2.00	Homo sapiens	TGACAGSTGTCA	TGACASCTGTCA	SELEX Yin et al.(2017) TGIF1_eDBD_HT-SELEX	0.631	0.527
TGIF1 M09159_2.00	Homo sapiens	TGACAGS	SCTGTCA	Misc Kulakovskiy et al.(2013) TGIF1_HUMAN.H11MO.0.A	0.631	0.527
Tgif1 M09211_2.00	Mus musculus	TGACAGBNV	BNVCTGTCA	Misc Kulakovskiy et al.(2013) TGIF1_MOUSE.H11MO.0.A	0.631	0.527
TGIF1 M10740_2.00	Homo sapiens	WHNTGACARST	ASYTGTCANDW	Transfac Matys et al.(2006) V$TGIF_01	0.631	0.527
TGIF1 M05318_2.00	Homo sapiens	TGACAKVTGTCA	TGACABMTGTCA	SELEX Yin et al.(2017) TGIF1_eDBD_Methyl-HT-SELEX	0.631	0.527
achi M03860_2.00	Drosophila melanogaster	TGACAD	HTGTCA	SELEX Nitta et al.(2015) achi_1	0.622	0.509
achi M03861_2.00	Drosophila melanogaster	TGACAGMTGTCA	TGACAKCTGTCA	SELEX Nitta et al.(2015) achi_2	0.622	0.509
achi M03862_2.00	Drosophila melanogaster	TGACAGNNNNNNYGTCA	TGACRNNNNNNCTGTCA	SELEX Nitta et al.(2015) achi_3	0.622	0.509
vis M03859_2.00	Drosophila melanogaster	TGACAS	STGTCA	SELEX Nitta et al.(2015) vis_1	0.622	0.509
vis M06534_2.00	Drosophila melanogaster	TGACAB	BTGTCA	B1H Mathelier et al.(2014) MA0252.1	0.622	0.509
achi M06535_2.00	Drosophila melanogaster	TGACAG	CTGTCA	B1H Mathelier et al.(2014) MA0207.1	0.622	0.509
achi M06345_2.00	Drosophila melanogaster	TGTCADW	WHTGACA	B1H Zhu et al.(2011) Achi_Cell_FBgn0033749	0.622	0.509
achi M06346_2.00	Drosophila melanogaster	HTGACA	TGTCAD	B1H Zhu et al.(2011) Achi_SOLEXA_FBgn0033749	0.622	0.509
vis M06343_2.00	Drosophila melanogaster	TGTCA	TGACA	B1H Zhu et al.(2011) Vis_Cell_FBgn0033748	0.622	0.509
vis M06344_2.00	Drosophila melanogaster	TGTCAD	HTGACA	B1H Zhu et al.(2011) Vis_SOLEXA_FBgn0033748	0.622	0.509
TGIF2LX M03171_2.00	Homo sapiens	TGACAGSTGTCA	TGACASCTGTCA	SELEX Jolma et al.(2013) TGIF2LX_1	0.601	0.509
TGIF2LX M05191_2.00	Homo sapiens	TGACABVTGTCA	TGACABVTGTCA	SELEX Yin et al.(2017) TGIF2LX_eDBD_HT-SELEX	0.601	0.509
TGIF2LX M05193_2.00	Homo sapiens	TGACASSTGTCA	TGACASSTGTCA	SELEX Yin et al.(2017) TGIF2LX_FL_HT-SELEX	0.601	0.509
TGIF2LX M05192_2.00	Homo sapiens	TGACABVTGTCA	TGACABVTGTCA	SELEX Yin et al.(2017) TGIF2LX_eDBD_Methyl-HT-SELEX	0.601	0.509
TGIF2LX M05194_2.00	Homo sapiens	TGACASSTGTCA	TGACASSTGTCA	SELEX Yin et al.(2017) TGIF2LX_FL_Methyl-HT-SELEX	0.601	0.509
TGIF2LY M05313_2.00	Homo sapiens	TGACABVTGTCA	TGACABVTGTCA	SELEX Yin et al.(2017) TGIF2LY_eDBD_HT-SELEX	0.601	0.491
TGIF2LY M05314_2.00	Homo sapiens	YGACABVTGTCR	YGACABVTGTCR	SELEX Yin et al.(2017) TGIF2LY_eDBD_Methyl-HT-SELEX	0.601	0.491
For this family, TFs with SR scores > 0.599* will likely have a similar motif*

DNA Binding Domains

Protein ID	Domain	From	To	Sequence
Afo_R001341	Homeodomain	271	328	KNKRGVLPKHATNIMRSWLFQHLMHPYPTEDEKRQIAAQTNLTLLQVNNWFINARRRI

Links
Other Homeodomain family TFs
Other *Aptenodytes forsteri* TFs

798 Related TFs

Name	Species	Gene ID	Motif Evidence	SR Score	Action
Aan_R011585	Calypte anna	Aan_R011585	I	0.000
Afo_R007908	Aptenodytes forsteri	Afo_R007908	I	0.000
Alligator_sinensis_CCG008027.1	Alligator sinensis	Alligator_sinensis_CCG008027.1	I	0.000
Brh_R009272	Buceros rhinoceros	Brh_R009272	I	0.000
Cmyd_10007723	Chelonia mydas	Cmyd_10007723	I	0.000
MAFF	Anolis carolinensis	ENSACAG00000008424	I	0.000
ENSAMEG00000010499	Ailuropoda melanoleuca	ENSAMEG00000010499	I	0.000
ENSAMXG00000008651	Astyanax mexicanus	ENSAMXG00000008651	I	0.000
MAFF	Bos taurus	ENSBTAG00000021435	I	0.000
MAFF	Canis familiaris	ENSCAFG00000029842	I	0.000
MAFF	Callithrix jacchus	ENSCJAG00000011992	I	0.000
ENSCSAG00000006757	Chlorocebus sabaeus	ENSCSAG00000006757	I	0.000
maff	Danio rerio	ENSDARG00000028957	I	0.000
Maff	Dipodomys ordii	ENSDORG00000013449	I	0.000
MAFF	Echinops telfairi	ENSETEG00000012984	I	0.000
ENSFALG00000012611	Ficedula albicollis	ENSFALG00000012611	I	0.000
MAFF	Homo sapiens	ENSG00000185022	D	0.000
mafgb	Gasterosteus aculeatus	ENSGACG00000019041	I	0.000
ENSGALG00000012277	Gallus gallus	ENSGALG00000012277	I	0.000
ENSLACG00000007109	Latimeria chalumnae	ENSLACG00000007109	I	0.000
MAFF	Loxodonta africana	ENSLAFG00000022547	I	0.000
ENSMEUG00000002984	Macropus eugenii	ENSMEUG00000002984	I	0.000
MAFF	Meleagris gallopavo	ENSMGAG00000015937	I	0.000
ENSMICG00000011572	Microcebus murinus	ENSMICG00000011572	I	0.000
MAFF	Myotis lucifugus	ENSMLUG00000011358	I	0.000
ENSMMUG00000013915	Macaca mulatta	ENSMMUG00000013915	I	0.000
ENSMMUP00000018288	Macaca fascicularis	ENSMMUP00000018288	I	0.000
MAFF	Monodelphis domestica	ENSMODG00000018732	I	0.000
ENSMPUG00000013085	Mustela putorius furo	ENSMPUG00000013085	I	0.000
Maff	Mus musculus	ENSMUSG00000042622	D	0.000
ENSNLEG00000015068	Nomascus leucogenys	ENSNLEG00000015068	I	0.000
MAFF	Oryctolagus cuniculus	ENSOCUG00000006266	I	0.000
MAFF	Otolemur garnettii	ENSOGAG00000027848	I	0.000
ENSONIG00000001329	Oreochromis niloticus	ENSONIG00000001329	I	0.000
ENSONIG00000019674	Oreochromis niloticus	ENSONIG00000019674	I	0.000
mafk	Oryzias latipes	ENSORLG00000004687	I	0.000
MAFG	Oryzias latipes	ENSORLG00000012170	I	0.000
ENSPANG00000020550	Papio anubis	ENSPANG00000020550	I	0.000
MAFF	Procavia capensis	ENSPCAG00000013370	I	0.000
ENSPFOG00000002983	Poecilia formosa	ENSPFOG00000002983	I	0.000
ENSPFOG00000005759	Poecilia formosa	ENSPFOG00000005759	I	0.000
ENSPFOG00000012736	Poecilia formosa	ENSPFOG00000012736	I	0.000
ENSPPYG00000011816	Pongo abelii	ENSPPYG00000011816	I	0.000
MAFF	Pan troglodytes	ENSPTRG00000029431	I	0.000
Maff	Rattus norvegicus	ENSRNOG00000012886	I	0.000
MAFF	Sus scrofa	ENSSSCG00000030165	I	0.000
ENSSTOG00000025460	Ictidomys tridecemlineatus	ENSSTOG00000025460	I	0.000
MAFF	Taeniopygia guttata	ENSTGUG00000010431	I	0.000
maff	Tetraodon nigroviridis	ENSTNIG00000001100	I	0.000
mafk	Tetraodon nigroviridis	ENSTNIG00000004471	I	0.000
mafk	Takifugu rubripes	ENSTRUG00000013716	I	0.000
maff	Takifugu rubripes	ENSTRUG00000016981	I	0.000
MAFF	Tursiops truncatus	ENSTTRG00000005618	I	0.000
ENSXMAG00000009331	Xiphophorus maculatus	ENSXMAG00000009331	I	0.000
ENSXMAG00000012964	Xiphophorus maculatus	ENSXMAG00000012964	I	0.000
Gfo_R004700	Geospiza fortis	Gfo_R004700	I	0.000
Ogr11652	Ophisaurus gracilis	Ogr11652	I	0.000
Ogr18387	Ophisaurus gracilis	Ogr18387	N	0.000
Pvit_08359	Pogona vitticeps	Pvit_08359	I	0.000

Afo_R001341 (Aptenodytes forsteri) Homeodomain

TF Information

Directly determined binding motifs

Motifs from related TFs

DNA Binding Domains

Links

798 Related TFs

Afo_R001341 **(Aptenodytes forsteri)
Homeodomain**