HSF5 (Homo sapiens)
HSF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00447 (HSF_DNA-bind) IPR000232 ENSG00000176160 T240227_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
HSF5
M05519_2.00		 Homo sapiens
NRCRTTCTAGAACGYN
NRCGTTCTAGAAYGYN		 SELEX
Yin et al.(2017)
HSF5_eDBD_HT-SELEX_1		 (Direct) (Direct)
HSF5
M05520_2.00		 Homo sapiens
YVGAAYRYNNNNNNNNNBHACRTTCBR
YVGAAYGTDVNNNNNNNNNRYRTTCBR		 SELEX
Yin et al.(2017)
HSF5_eDBD_HT-SELEX_2		 (Direct) (Direct)
HSF5
M05521_2.00		 Homo sapiens
AACRTTCTAGAAYGTT
AACRTTCTAGAAYGTT		 SELEX
Yin et al.(2017)
HSF5_eDBD_Methyl-HT-SELEX_1		 (Direct) (Direct)
HSF5
M05522_2.00		 Homo sapiens
YRGAAYDYNVNNNNNNNBAACRTTCYR
YRGAAYGTTVNNNNNNNBNRHRTTCYR		 SELEX
Yin et al.(2017)
HSF5_eDBD_Methyl-HT-SELEX_2		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
HSFY2
M03326_2.00 		Homo sapiens
WTCGAWNVRWTCGAW
WTCGAWYBNWTCGAW		 SELEX
Jolma et al.(2013)
HSFY2_1 		0.323 0.432
HSFY2
M03327_2.00 		Homo sapiens
CRTTCGAWW
WWTCGAAYG		 SELEX
Jolma et al.(2013)
HSFY2_2 		0.323 0.432
HSFY2
M03328_2.00 		Homo sapiens
DTCGAAHSNWTCGAW
WTCGAWNSDTTCGAH		 SELEX
Jolma et al.(2013)
HSFY2_3 		0.323 0.432
HSFY1
M05515_2.00 		Homo sapiens
NDTVGAAYGWTTCGAAYGB
VCRTTCGAAWCRTTCBAHN		 SELEX
Yin et al.(2017)
HSFY1_eDBD_HT-SELEX_1 		0.323 0.432
HSFY1
M05516_2.00 		Homo sapiens
DTTCGAAHSDTTCGAAH
DTTCGAAHSDTTCGAAH		 SELEX
Yin et al.(2017)
HSFY1_eDBD_HT-SELEX_2 		0.323 0.432
HSFY2
M05511_2.00 		Homo sapiens
NDTVGAAYGWTTCGAAYGB
VCRTTCGAAWCRTTCBAHN		 SELEX
Yin et al.(2017)
HSFY2_eDBD_HT-SELEX_1 		0.323 0.432
HSFY2
M05512_2.00 		Homo sapiens
DTTCGAAHSDTTCGAAH
DTTCGAAHSDTTCGAAH		 SELEX
Yin et al.(2017)
HSFY2_eDBD_HT-SELEX_2 		0.323 0.432
HSFY1
M05517_2.00 		Homo sapiens
NDTRGAATGTTTRGAATGB
VCATTCYAAACATTCYAHN		 SELEX
Yin et al.(2017)
HSFY1_eDBD_Methyl-HT-SELEX_1 		0.323 0.432
HSFY1
M05518_2.00 		Homo sapiens
DTTCGAAHSDTTCGAAH
DTTCGAAHSDTTCGAAH		 SELEX
Yin et al.(2017)
HSFY1_eDBD_Methyl-HT-SELEX_2 		0.323 0.432
HSFY2
M05513_2.00 		Homo sapiens
NDWRGAAYGTTTRGAAYGB
VCRTTCYAAACRTTCYWHN		 SELEX
Yin et al.(2017)
HSFY2_eDBD_Methyl-HT-SELEX_1 		0.323 0.432
HSFY2
M05514_2.00 		Homo sapiens
DTTCGAAHSDTTCGAAH
DTTCGAAHSDTTCGAAH		 SELEX
Yin et al.(2017)
HSFY2_eDBD_Methyl-HT-SELEX_2 		0.323 0.432
For this family, TFs with SR scores > 0.318 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000313243 HSF 14 131

Links

Other HSF family TFs
Other Homo sapiens TFs

72 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ENSAMEG00000014907 Ailuropoda melanoleuca ENSAMEG00000014907 I 0.374
ENSAMXG00000015946 Astyanax mexicanus ENSAMXG00000015946 I 0.395
HSF5 Bos taurus ENSBTAG00000001166 I 0.658
ENSBTAG00000047120 Bos taurus ENSBTAG00000047120 I 0.320
ENSBTAP00000044770-D1 Bos grunniens ENSBTAP00000044770-D1 I 0.318
HSF5 Canis familiaris ENSCAFG00000017528 I 0.658
ENSCAFG00000023067 Canis familiaris ENSCAFG00000023067 I 0.380
ENSCAFG00000029639 Canis familiaris ENSCAFG00000029639 I 0.380
HSF5 Cavia porcellus ENSCPOG00000003431 I 0.562
ENSCSAG00000007182 Chlorocebus sabaeus ENSCSAG00000007182 I 0.329
hsf5 Danio rerio ENSDARG00000104686 I 0.370
HSF5 Dasypus novemcinctus ENSDNOG00000014871 I 0.658
ENSECAG00000008677 Equus caballus ENSECAG00000008677 I 0.348
ENSECAG00000008708 Equus caballus ENSECAG00000008708 I 0.342
ENSECAG00000009495 Equus caballus ENSECAG00000009495 I 0.342
HSF5 Erinaceus europaeus ENSEEUG00000012375 I 0.525
HSF5 Echinops telfairi ENSETEG00000014190 I 0.451
ENSFALG00000014220 Ficedula albicollis ENSFALG00000014220 I 0.372
HSFY2 Homo sapiens ENSG00000169953 D 0.323
HSFX1 Homo sapiens ENSG00000171116 I 0.338
HSFY1 Homo sapiens ENSG00000172468 D 0.323
HSFX2 Homo sapiens ENSG00000268738 I 0.338
HSF5 Gallus gallus ENSGALG00000001031 I 0.542
HSF5 Gorilla gorilla ENSGGOG00000013788 I 0.657
ENSGMOG00000013287 Gadus morhua ENSGMOG00000013287 I 0.345
ENSLACG00000015426 Latimeria chalumnae ENSLACG00000015426 I 0.503
HSF5 Loxodonta africana ENSLAFG00000029785 I 0.579
ENSLOCG00000002988 Lepisosteus oculatus ENSLOCG00000002988 I 0.450
ENSMEUG00000007286 Macropus eugenii ENSMEUG00000007286 I 0.658
HSF5 Myotis lucifugus ENSMLUG00000006132 I 0.534
ENSMLUG00000015387 Myotis lucifugus ENSMLUG00000015387 I 0.324
ENSMLUG00000022730 Myotis lucifugus ENSMLUG00000022730 I 0.329
ENSMMUG00000002887 Macaca mulatta ENSMMUG00000002887 I 0.336
HSF5 Macaca mulatta ENSMMUG00000004184 I 0.415
Hsfy2 Mus musculus ENSMUSG00000045336 I 0.325
Hsf5 Mus musculus ENSMUSG00000070345 I 0.658
ENSNLEG00000013483 Nomascus leucogenys ENSNLEG00000013483 I 0.350
ENSOARG00000003920 Ovis aries ENSOARG00000003920 I 0.325
HSF5 Oryctolagus cuniculus ENSOCUG00000009733 I 0.556
ENSOCUG00000025707 Oryctolagus cuniculus ENSOCUG00000025707 I 0.338
ENSP00000359444 Macaca fascicularis ENSP00000359444 I 0.336
ENSPANG00000004032 Papio anubis ENSPANG00000004032 I 0.336
HSF5 Procavia capensis ENSPCAG00000011323 I 0.658
ENSPFOG00000024243 Poecilia formosa ENSPFOG00000024243 I 0.368
ENSPPYG00000008231 Pongo abelii ENSPPYG00000008231 I 0.658
ENSPPYG00000020808 Pongo abelii ENSPPYG00000020808 I 0.371
HSF5 Pan troglodytes ENSPTRG00000009453 I 0.680
HSF5 Pteropus vampyrus ENSPVAG00000002322 I 0.605
Hsfy2 Rattus norvegicus ENSRNOG00000038569 I 0.325
ENSSSCG00000012732 Sus scrofa ENSSSCG00000012732 I 0.351
HSF5 Sus scrofa ENSSSCG00000017641 I 0.658
ENSSTOG00000020272 Ictidomys tridecemlineatus ENSSTOG00000020272 I 0.658
ENSTGUG00000015457 Taeniopygia guttata ENSTGUG00000015457 I 0.414
ENSTNIG00000008554 Tetraodon nigroviridis ENSTNIG00000008554 I 0.353
ENSTNIG00000019152 Tetraodon nigroviridis ENSTNIG00000019152 I 0.329
ENSTRUG00000004613 Takifugu rubripes ENSTRUG00000004613 I 0.348
ENSTRUG00000008763 Takifugu rubripes ENSTRUG00000008763 I 0.350
ENSTRUG00000010837 Takifugu rubripes ENSTRUG00000010837 I 0.349
ENSTRUG00000012122 Takifugu rubripes ENSTRUG00000012122 I 0.331
ENSTRUG00000015486 Takifugu rubripes ENSTRUG00000015486 I 0.353
ENSTRUG00000016913 Takifugu rubripes ENSTRUG00000016913 I 0.326
ENSTRUG00000017318 Takifugu rubripes ENSTRUG00000017318 I 0.337
HSF5 Tursiops truncatus ENSTTRG00000006851 I 0.507
estExt_fgenesh2_pg.C_2160042 Branchiostoma floridae estExt_fgenesh2_pg.C_2160042 I 0.324
estExt_fgenesh2_pg.C_2160046 Branchiostoma floridae estExt_fgenesh2_pg.C_2160046 I 0.324
estExt_fgenesh2_pg.C_500047 Branchiostoma floridae estExt_fgenesh2_pg.C_500047 I 0.330
estExt_fgenesh2_pg.C_70302 Branchiostoma floridae estExt_fgenesh2_pg.C_70302 I 0.330
fgenesh2_pg.scaffold_142000054 Branchiostoma floridae fgenesh2_pg.scaffold_142000054 I 0.323
fgenesh2_pg.scaffold_315000002 Branchiostoma floridae fgenesh2_pg.scaffold_315000002 I 0.350
maker-pag1_scaffold_1127-snap-gene-0.1 Pythium aphanidermatum maker-pag1_scaffold_1127-snap-gene-0.1 I 0.339
Myotis_brandtii_HSFY1_10020625 Myotis brandtii Myotis_brandtii_HSFY1_10020625 I 0.335
Pvit_11979 Pogona vitticeps Pvit_11979 I 0.329