IRF1 (Homo sapiens)
IRF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00605 (IRF) IPR001346 ENSG00000125347 T244078_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
IRF1
M08142_2.00		 Homo sapiens
RWANNGAAASYGAAASYRNNN
NNNYRSTTTCRSTTTCNNTWY		 ChIP-seq
Mathelier et al.(2014)
MA0050.2		 (Direct) (Direct)
IRF1
M09233_2.00		 Homo sapiens
NRAANNGAAASWGAAASHRN
NYDSTTTCWSTTTCNNTTYN		 Misc
Kulakovskiy et al.(2013)
IRF1_HUMAN.H11MO.0.A		 (Direct) (Direct)
IRF1
M09594_2.00		 Homo sapiens
GAAASTGAAASY
RSTTTCASTTTC		 Misc
Heinz et al.(2010)
PBMC-IRF1_GSE43036		 (Direct) (Direct)
IRF1
M10879_2.00		 Homo sapiens
SAAAASYGAAASY
RSTTTCRSTTTTS		 Transfac
Matys et al.(2006)
V$IRF1_01		 (Direct) (Direct)
IRF1
M10880_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$IRF1_03		 (Direct) (Direct)
IRF1
M10881_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$IRF1_Q5		 (Direct) (Direct)
IRF1
M10882_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$IRF1_Q6		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Irf1
M09242_2.00 		Mus musculus
VRAANNGAAASYGAAASYVN
NBRSTTTCRSTTTCNNTTYB		 Misc
Kulakovskiy et al.(2013)
IRF1_MOUSE.H11MO.0.A 		1.000 1.000
Irf2
M00805_2.00 		Mus musculus
NDWNHGAAAV
BTTTCDNWHN		 PBM
Weirauch et al.(2013)
pTH2835 		0.771 0.771
IRF2
M05545_2.00 		Homo sapiens
NGAAAVYGAAAS
STTTCRBTTTCN		 SELEX
Yin et al.(2017)
IRF2_FL_HT-SELEX 		0.771 0.771
IRF2
M02691_2.00 		Homo sapiens
SGAAAGYGAAASYNWWHH
DDWWNRSTTTCRCTTTCS		 SELEX
Mathelier et al.(2014)
MA0051.1 		0.771 0.771
IRF2
M09237_2.00 		Homo sapiens
NRAANNGAAASYGAAASYRV
BYRSTTTCRSTTTCNNTTYN		 Misc
Kulakovskiy et al.(2013)
IRF2_HUMAN.H11MO.0.A 		0.771 0.771
Irf2
M09245_2.00 		Mus musculus
NRAANNGAAASYGAAASYRV
BYRSTTTCRSTTTCNNTTYN		 Misc
Kulakovskiy et al.(2013)
IRF2_MOUSE.H11MO.0.B 		0.771 0.771
IRF2
M09596_2.00 		Homo sapiens
NRAAVNRRAASB
VSTTYYNBTTYN		 Misc
Heinz et al.(2010)
Erythroblas-IRF2_GSE36985 		0.771 0.771
IRF2
M10892_2.00 		Homo sapiens
GAAAAGYGAAASY
RSTTTCRCTTTTC		 Transfac
Matys et al.(2006)
V$IRF2_01 		0.771 0.771
IRF2
M10893_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$IRF2_Q6 		0.771 0.771
IRF2
M05546_2.00 		Homo sapiens
NGAAASYGAAAS
STTTCRSTTTCN		 SELEX
Yin et al.(2017)
IRF2_FL_Methyl-HT-SELEX 		0.771 0.771
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000245414 IRF 7 112
ENSP00000384406 IRF 7 112
ENSP00000392455 IRF 7 45
ENSP00000396318 IRF 7 112
ENSP00000405655 IRF 7 112
ENSP00000473661 IRF 7 112
ENSP00000480887 IRF 7 112

Links

Other IRF family TFs
Other Homo sapiens TFs

128 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ALUE_0001885601 Ascaris lumbricoides ALUE_0001885601 N
ANCCEY_01474 Ancylostoma ceylanicum ANCCEY_01474 N
ASU_15182 Ascaris suum ASU_15182 N
Bm6550 Brugia malayi Bm6550 N
CBG05690 Caenorhabditis briggsae CBG05690 N
CBN07630 Caenorhabditis brenneri CBN07630 N
CRE06043 Caenorhabditis remanei CRE06043 N
DME_0000028701 Dracunculus medinensis DME_0000028701 N
EEL_0000847601 Elaeophora elaphi EEL_0000847601 N
EVEC_0001283901 Enterobius vermicularis EVEC_0001283901 N
Hba_18486 Heterorhabditis bacteriophora Hba_18486 N
HPLM_0001382501 Haemonchus placei HPLM_0001382501 N
L889_g14208 Steinernema feltiae L889_g14208 N
L892_g27879 Steinernema scapterisci L892_g27879 I
LOAG_13296 Loa loa LOAG_13296 N
NBR_0000071001 Nippostrongylus brasiliensis NBR_0000071001 N
PEQ_0000560001 Parascaris equorum PEQ_0000560001 N
PTRK_0001116100 Parastrongyloides trichosuri PTRK_0001116100 N
RSKR_0000247700 Rhabditophanes kr3021 RSKR_0000247700 N
SMUV_0000467601 Syphacia muris SMUV_0000467601 N
SPAL_0001355700 Strongyloides papillosus SPAL_0001355700 N
SSTP_0000731600 Strongyloides stercoralis SSTP_0000731600 N
SSTP_0000839900 Strongyloides stercoralis SSTP_0000839900 N
TCLT_0000242201 Thelazia callipaeda TCLT_0000242201 N
TCNE_0001625401 Toxocara canis TCNE_0001625401 N
dmd-3 Caenorhabditis elegans WBGene00012832 D
WBGene00242840 Onchocerca volvulus WBGene00242840 N