CIS-BP Database: Catalog of Inferred Sequence Binding Preferences
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IRF8
(
Homo sapiens
)
IRF
TF Information
Pfam ID
Interpro ID
Gene ID
CIS-BP ID
Sequence source
Animal TF db
PF00605 (IRF)
IPR001346
ENSG00000140968
T244082_2.00
Ensembl (2018-Dec-8)
Link out
Directly determined binding motifs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
IRF8
M03335_2.00
Homo sapiens
HCGAAACYGAAACY
RGTTTCRGTTTCGD
SELEX
Jolma et al.(2013)
IRF8_1
(Direct)
(Direct)
IRF8
M03336_2.00
Homo sapiens
HCGAAACCGAAACT
AGTTTCGGTTTCGD
SELEX
Jolma et al.(2013)
IRF8_2
(Direct)
(Direct)
IRF8
M05541_2.00
Homo sapiens
NYGAAASYGAAASHN
NDSTTTCRSTTTCRN
SELEX
Yin et al.(2017)
IRF8_eDBD_HT-SELEX
(Direct)
(Direct)
IRF8
M05542_2.00
Homo sapiens
NYGAAASYGAAASYN
NRSTTTCRSTTTCRN
SELEX
Yin et al.(2017)
IRF8_eDBD_Methyl-HT-SELEX
(Direct)
(Direct)
IRF8
M05543_2.00
Homo sapiens
NCGAAACYGAAACYN
NRGTTTCRGTTTCGN
SELEX
Yin et al.(2017)
IRF8_FL_HT-SELEX
(Direct)
(Direct)
IRF8
M05544_2.00
Homo sapiens
NYGAAASYGAAACYD
HRGTTTCRSTTTCRN
SELEX
Yin et al.(2017)
IRF8_FL_Methyl-HT-SELEX
(Direct)
(Direct)
IRF8
M09236_2.00
Homo sapiens
NDDDRRGGAASTGAAASYNN
NNRSTTTCASTTCCYYHHHN
Misc
Kulakovskiy et al.(2013)
IRF8_HUMAN.H11MO.0.B
(Direct)
(Direct)
IRF8
M10890_2.00
Homo sapiens
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$ICSBP_Q6
(Direct)
(Direct)
IRF8
M10891_2.00
Homo sapiens
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$IRF8_Q6
(Direct)
(Direct)
Motifs from related TFs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
Irf8
M09246_2.00
Mus musculus
NDDDRRGGAASTGAAASYNN
NNRSTTTCASTTCCYYHHHN
Misc
Kulakovskiy et al.(2013)
IRF8_MOUSE.H11MO.0.A
0.949
0.949
Irf4
M00175_2.00
Mus musculus
NNNYGAWASN
NSTWTCRNNN
PBM
Badis et al.(2009)
Irf4_3476
0.817
0.817
IRF4
M03334_2.00
Homo sapiens
HCGAAACCGAAACYW
WRGTTTCGGTTTCGD
SELEX
Jolma et al.(2013)
IRF4_1
0.817
0.817
IRF4
M05539_2.00
Homo sapiens
NYGAAACYGAAACYN
NRGTTTCRGTTTCRN
SELEX
Yin et al.(2017)
IRF4_FL_HT-SELEX
0.817
0.817
IRF4
M07978_2.00
Homo sapiens
DNDVNNGWWVTGAVWVWN
NWBWBTCABWWCNNBHNH
ChIP-seq
Gerstein et al.(2012)
GM12878_IRF4_HudsonAlpha
0.817
0.817
IRF4
M09235_2.00
Homo sapiens
NDWDRRGGAASTGARAVH
DBTYTCASTTCCYYHWHN
Misc
Kulakovskiy et al.(2013)
IRF4_HUMAN.H11MO.0.A
0.846
0.846
Irf4
M09243_2.00
Mus musculus
NDAWVVRGAASTGARAVH
DBTYTCASTTCYBBWTHN
Misc
Kulakovskiy et al.(2013)
IRF4_MOUSE.H11MO.0.A
0.846
0.846
IRF4
M09595_2.00
Homo sapiens
HNYGAAASYD
HRSTTTCRND
Misc
Heinz et al.(2010)
GM12878-IRF4_GSE32465
0.846
0.846
IRF4
M10885_2.00
Homo sapiens
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$IRF4_07
0.846
0.846
IRF4
M10886_2.00
Homo sapiens
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$IRF4_08
0.846
0.846
IRF4
M10887_2.00
Homo sapiens
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$IRF4_Q5_01
0.817
0.817
IRF4
M10888_2.00
Homo sapiens
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$IRF4_Q5
0.817
0.817
IRF4
M10889_2.00
Homo sapiens
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$IRF4_Q6
0.817
0.817
IRF4
M05540_2.00
Homo sapiens
NYGAAASYGAWASHN
NDSTWTCRSTTTCRN
SELEX
Yin et al.(2017)
IRF4_FL_Methyl-HT-SELEX
0.817
0.817
For this family, TFs with SR scores >
0.700
will likely have a similar motif
DNA Binding Domains
Protein ID
Domain
From
To
Sequence
ENSP00000268638
IRF
9
113
RLRQWLIEQIDSSMYPGLIWENEEKSMFRIPWKHAGKQDYNQEVDASIFKAWAVFKGKFKEGDKAEPATWKTRLRCALNKSPDFEEVTDRSQLDISEPYKVYRIV
ENSP00000455048
IRF
1
56
XAWAVFKGKFKEGDKAEPATWKTRLRCALNKSPDFEEVTDRSQLDISEPYKVYRIV
ENSP00000455784
IRF
9
113
RLRQWLIEQIDSSMYPGLIWENEEKSMFRIPWKHAGKQDYNQEVDASIFKAWAVFKGKFKEGDKAEPATWKTRLRCALNKSPDFEEVTDRSQLDISEPYKVYRIV
ENSP00000455816
IRF
9
47
RLRQWLIEQIDSSMYPGLIWENEEKSMFRIPWKHAGKQD
ENSP00000456992
IRF
9
113
RLRQWLIEQIDSSMYPGLIWENEEKSMFRIPWKHAGKQDYNQEVDASIFKAWAVFKGKFKEGDKAEPATWKTRLRCALNKSPDFEEVTDRSQLDISEPYKVYRIV
ENSP00000458047
IRF
9
113
RLRQWLIEQIDSSMYPGLIWENEEKSMFRIPWKHAGKQDYNQEVDASIFKAWAVFKGKFKEGDKAEPATWKTRLRCALNKSPDFEEVTDRSQLDISEPYKVYRIV
Links
Other
IRF
family TFs
Other
Homo sapiens
TFs
166 Related TFs
Name
Species
Gene ID
Motif Evidence
SR
Score
Action
AGABI2DRAFT_224213
Agaricus bisporus
AGABI2DRAFT_224213
N
0.000
BOTBODRAFT_50846
Botryobasidium botryosum
BOTBODRAFT_50846
N
0.000
CERSUDRAFT_89102
Ceriporiopsis subvermispora
CERSUDRAFT_89102
N
0.000
CY34DRAFT_21340
Suillus luteus
CY34DRAFT_21340
N
0.000
estExt_Genewise1.C_70735
Heterobasidion annosum
estExt_Genewise1.C_70735
N
0.000
FIBRA_04563
Fibroporia radiculosa
FIBRA_04563
N
0.000
FOMPIDRAFT_1031471
Fomitopsis pinicola
FOMPIDRAFT_1031471
N
0.000
GALMADRAFT_238181
Galerina marginata
GALMADRAFT_238181
N
0.000
GLOTRDRAFT_66280
Gloeophyllum trabeum
GLOTRDRAFT_66280
N
0.000
HETIRDRAFT_384208
Heterobasidion irregulare
HETIRDRAFT_384208
N
0.000
HYDPIDRAFT_182671
Hydnomerulius pinastri
HYDPIDRAFT_182671
N
0.000
JAAARDRAFT_30454
Jaapia argillacea
JAAARDRAFT_30454
N
0.000
K443DRAFT_672892
Laccaria amethystina
K443DRAFT_672892
N
0.000
LACBIDRAFT_309255
Laccaria bicolor
LACBIDRAFT_309255
N
0.000
M404DRAFT_248099
Pisolithus tinctorius
M404DRAFT_248099
N
0.000
M407DRAFT_30153
Tulasnella calospora
M407DRAFT_30153
N
0.000
M408DRAFT_198102
Serendipita vermifera
M408DRAFT_198102
N
0.000
M413DRAFT_444187
Hebeloma cylindrosporum
M413DRAFT_444187
N
0.000
M422DRAFT_55406
Sphaerobolus stellatus
M422DRAFT_55406
N
0.000
Moror_12409
Moniliophthora roreri
Moror_12409
N
0.000
PAXRUDRAFT_143066
Paxillus rubicundulus
PAXRUDRAFT_143066
N
0.000
PHACADRAFT_262394
Phanerochaete carnosa
PHACADRAFT_262394
N
0.000
PHLGIDRAFT_126149
Phlebiopsis gigantea
PHLGIDRAFT_126149
N
0.000
PIIN_00682
Piriformospora indica
PIIN_00682
N
0.000
PILCRDRAFT_812975
Piloderma croceum
PILCRDRAFT_812975
N
0.000
PISMIDRAFT_684265
Pisolithus microcarpus
PISMIDRAFT_684265
N
0.000
PLEOSDRAFT_1044878
Pleurotus ostreatus
PLEOSDRAFT_1044878
N
0.000
SCHCODRAFT_81726
Schizophyllum commune
SCHCODRAFT_81726
N
0.000
SERLA73DRAFT_55337
Serpula lacrymans
SERLA73DRAFT_55337
N
0.000