TP63 (Homo sapiens)
p53

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00870 (P53) IPR011615 ENSG00000073282 T311038_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
TP63
M03437_2.00		 Homo sapiens
DACATGTYVYRACATGTY
RACATGTYRBRACATGTH		 SELEX
Jolma et al.(2013)
TP63_1		 (Direct) (Direct)
TP63
M09335_2.00		 Homo sapiens
DRCAWGYHCHRRCHTGYHN
NDRCADGYYDGDRCWTGYH		 Misc
Kulakovskiy et al.(2013)
P63_HUMAN.H11MO.0.A		 (Direct) (Direct)
TP63
M11195_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$P63_01		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Trp63
M09338_2.00 		Mus musculus
DRCAWGYHCHRRCHTGYHN
NDRCADGYYDGDRCWTGYH		 Misc
Kulakovskiy et al.(2013)
P63_MOUSE.H11MO.0.B 		1.000 1.000
Trp73
M03438_2.00 		Mus musculus
DRCAWGTYNNRACAYGYH
DRCRTGTYNNRACWTGYH		 SELEX
Jolma et al.(2013)
Tp73_1 		0.857 0.857
TP73
M08035_2.00 		Homo sapiens
RCADGYHSDGRCWDG
CHWGYCHSDRCHTGY		 ChIP-seq
Chen et al.(2011)
GSE15704_TP73_rapamycin 		0.802 0.802
TP73
M08036_2.00 		Homo sapiens
DRRCAWGYHCWGRCWTGYH
DRCAWGYCWGDRCWTGYYH		 ChIP-seq
Chen et al.(2011)
GSE15704_TP73_vehicle 		0.802 0.802
TP73
M08037_2.00 		Homo sapiens
RCMDGYBCHNDCHKG
CMDGHNDGVRCHKGY		 ChIP-seq
Chen et al.(2011)
GSE18650_TP73 		0.857 0.857
TP73
M09336_2.00 		Homo sapiens
NDDCHWGYYCMRRCHTGYH
DRCADGYYKGRRCWDGHHN		 Misc
Kulakovskiy et al.(2013)
P73_HUMAN.H11MO.0.A 		0.857 0.857
Trp73
M09339_2.00 		Mus musculus
NDDCHWGYYCMRRCHTGYH
DRCADGYYKGRRCWDGHHN		 Misc
Kulakovskiy et al.(2013)
P73_MOUSE.H11MO.0.B 		0.857 0.857
TP73
M11196_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$P73_Q6 		0.857 0.857
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000264731 p53 163 359
ENSP00000317510 p53 163 359
ENSP00000346614 p53 69 265
ENSP00000376253 p53 163 359
ENSP00000376254 p53 69 265
ENSP00000376256 p53 69 265
ENSP00000387839 p53 3 180
ENSP00000389485 p53 69 265
ENSP00000392488 p53 69 265
ENSP00000394337 p53 163 359
ENSP00000401661 p53 69 141
ENSP00000401661 p53 148 183
ENSP00000407144 p53 163 359

Links

Other p53 family TFs
Other Homo sapiens TFs

125 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ACRE_080110 Acremonium chrysogenum ACRE_080110 I
BBA_00844 Beauveria bassiana BBA_00844 I
Bcin02g03240 Botrytis cinerea Bcin02g03240 I
BGHDH14_bgh06583 Blumeria graminis BGHDH14_bgh06583 I
CFIO01_02423 Colletotrichum fioriniae CFIO01_02423 I
CH063_08904 Colletotrichum higginsianum CH063_08904 I
CHGG_02493 Chaetomium globosum CHGG_02493 I
CMQ_6262 Grosmannia clavigera CMQ_6262 I
Cob_03179 Colletotrichum orbiculare Cob_03179 I
CPUR_06716 Claviceps purpurea CPUR_06716 I
CSUB01_04857 Colletotrichum sublineola CSUB01_04857 I
estExt_fgenesh2_pg.C_10626 Neurospora discreta estExt_fgenesh2_pg.C_10626 I
estExt_Genewise1Plus.C_sca_6_chr9_2_00224 Nectria haematococca estExt_Genewise1Plus.C_sca_6_chr9_2_00224 I
F503_08286 Ophiostoma piceae uamh F503_08286 I
FFUJ_02554 Fusarium fujikuroi FFUJ_02554 I
FGRRES_07368 Fusarium graminearum FGRRES_07368 I
FOXG_01519 Fusarium oxysporum FOXG_01519 I
FOXG_16654 Fusarium oxysporum FOXG_16654 I
FOXG_16719 Fusarium oxysporum FOXG_16719 I
FPSE_04183 Fusarium pseudograminearum FPSE_04183 I
FVEG_07882 Fusarium verticillioides FVEG_07882 I
GGTG_00491 Gaeumannomyces graminis GGTG_00491 I
GLRG_03014 Colletotrichum graminicola GLRG_03014 I
GMDG_03522 Pseudogymnoascus destructans GMDG_03522 I
HMPREF1624_00394 Sporothrix schenckii HMPREF1624_00394 I
MAJ_01995 Metarhizium majus MAJ_01995 I
MAM_07515 Metarhizium album MAM_07515 I
MANI_016433 Metarhizium anisopliae MANI_016433 I
MBM_08507 Marssonina brunnea MBM_08507 I
MBR_03822 Metarhizium brunneum MBR_03822 I
MGG_08185 Magnaporthe oryzae MGG_08185 I
MGU_05879 Metarhizium guizhouense MGU_05879 I
MYCTH_2300984 Myceliophthora thermophila MYCTH_2300984 I
NCU01386 Neurospora crassa NCU01386 D
NechaG71721 Fusarium solani NechaG71721 I
NEUTE1DRAFT_119830 Neurospora tetrasperma NEUTE1DRAFT_119830 I
OCS_04243 Ophiocordyceps sinensis OCS_04243 I
PFICI_07768 Pestalotiopsis fici PFICI_07768 I
PODANS_2_9090 Podospora anserina PODANS_2_9090 N
S40285_07444 Stachybotrys chlorohalonata S40285_07444 I
S40288_01221 Stachybotrys chartarum S40288_01221 I
SBOR_3407 Sclerotinia borealis SBOR_3407 I
SMAC_08362 Sordaria macrospora SMAC_08362 I
SPBR_06705 Sporothrix brasiliensis SPBR_06705 I
SS1G_01733 Sclerotinia sclerotiorum SS1G_01733 I
TRIATDRAFT_53110 Trichoderma atroviride TRIATDRAFT_53110 I
TRIVIDRAFT_33856 Trichoderma virens TRIVIDRAFT_33856 N
UV8b_2421 Ustilaginoidea virens UV8b_2421 I
V499_06325 Pseudogymnoascus pannorum V499_06325 I
VDAG_08406 Verticillium dahliae VDAG_08406 I
X797_006189 Metarhizium robertsii X797_006189 I
X797_010922 Metarhizium robertsii X797_010922 I
X797_011329 Metarhizium robertsii X797_011329 I
X797_012204 Metarhizium robertsii X797_012204 I