CIS-BP Database: Catalog of Inferred Sequence Binding Preferences
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Cic
(
Rattus norvegicus
)
Sox
TF Information
Pfam ID
Interpro ID
Gene ID
CIS-BP ID
Sequence source
Animal TF db
PF00505 (HMG_box)
IPR000910
ENSRNOG00000056118
T329079_2.00
Ensembl (2018-Dec-8)
Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Predicted to be involved in several processes, including learning or memory; regulation of transcription, DNA-templated; and social behavior. Predicted to act upstream of or within lung alveolus development and negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Predicted to be part of protein-containing complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in autosomal dominant mental retardation 45. Orthologous to human CIC (capicua transcriptional repressor). [provided by Alliance of Genome Resources, Apr 2022]
Directly determined binding motifs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
No direct experiments
Motifs from related TFs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
Cic
M00195_2.00
Mus musculus
NNTGCTGABN
NVTCAGCANN
PBM
Badis et al.(2009)
Cic_3454
0.741
1.000
cic
M06452_2.00
Drosophila melanogaster
YYCATTSA
TSAATGRR
B1H
Zhu et al.(2011)
cic_SANGER_5_FBgn0028386
0.680
0.768
gei-3
M00711_2.00
Caenorhabditis elegans
NWNWMWDN
NHWKWNWN
PBM
Narasimhan et al.(2015)
pTH10038
0.678
0.797
BBX
M05763_2.00
Homo sapiens
TGAWCDNYGWTCA
TGAWCRNHGWTCA
SELEX
Yin et al.(2017)
BBX_eDBD_HT-SELEX
0.468
0.594
BBX
M05764_2.00
Homo sapiens
TGAACDNYGTTCA
TGAACRNHGTTCA
SELEX
Yin et al.(2017)
BBX_eDBD_Methyl-HT-SELEX
0.468
0.594
ROX1
M00070_2.00
Saccharomyces cerevisiae
NRAACAATWNN
NNWATTGTTYN
PBM
Badis et al.(2008)
ROX1_2099
0.440
0.333
ROX1
M07498_2.00
Saccharomyces cerevisiae
YYHATTGTTYTS
SARAACAATDRR
PBM, CSA and or DIP-chip
Mathelier et al.(2014)
MA0371.1
0.440
0.333
ROX1
M08607_2.00
Saccharomyces cerevisiae
BYATTGTN
NACAATRV
Misc
DeBoer et al.(2011)
YPR065W_1396
0.440
0.333
ROX1
M11346_2.00
Saccharomyces cerevisiae
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
F$ROX1_Q6_01
0.440
0.333
ROX1
M11347_2.00
Saccharomyces cerevisiae
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
F$ROX1_Q6
0.440
0.333
bbx
M03975_2.00
Drosophila melanogaster
NAACAATDNCATTGTTN
NAACAATGNHATTGTTN
SELEX
Nitta et al.(2015)
bbx_1
0.440
0.536
Bbx
M00196_2.00
Mus musculus
TTCATTGA
TCAATGAA
PBM
Badis et al.(2009)
Bbx_3753
0.434
0.580
For this family, TFs with SR scores >
0.415
will likely have a similar motif
DNA Binding Domains
Protein ID
Domain
From
To
Sequence
ENSRNOP00000073956
Sox
200
268
IRRPMNAFMIFSKRHRALVHQRHPNQDNRTVSKILGEWWYALGPKEKQKYHDLAFQVKEAHFKAHPDWK
Links
Other
Sox
family TFs
Other
Rattus norvegicus
TFs
477 Related TFs
Name
Species
Gene ID
Motif Evidence
SR
Score
Action
Invalid Input OrderBy