CIS-BP Database: Catalog of Inferred Sequence Binding Preferences

TF Information

TFAP2E *(Oryctolagus cuniculus)* AP-2
Pfam ID	Interpro ID	Gene ID	CIS-BP ID	Sequence source	Animal TF db
PF03299 (TF_AP-2)	IPR013854	ENSOCUG00000013190	T010928_2.00	Ensembl (2018-Dec-8)	Link out
Directly determined binding motifs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
No direct experiments
Motifs from related TFs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
TFAP2E M04050_2.00	Homo sapiens	HSCCYSRGGSD	HSCCYSRGGSD	SELEX Yin et al.(2017) TFAP2E_FL_HT-SELEX_1	0.979	0.979
TFAP2E M04051_2.00	Homo sapiens	NSCCBBVGGSCA	TGSCCBVVGGSN	SELEX Yin et al.(2017) TFAP2E_FL_HT-SELEX_2	0.979	0.979
TFAP2E M04052_2.00	Homo sapiens	HSCCYSRGGSD	HSCCYSRGGSD	SELEX Yin et al.(2017) TFAP2E_FL_Methyl-HT-SELEX_1	0.979	0.979
TFAP2E M04053_2.00	Homo sapiens	NSCCYNRGGGCR	YGCCCYNRGGSN	SELEX Yin et al.(2017) TFAP2E_FL_Methyl-HT-SELEX_2	0.979	0.979
Tfap2e M00114_2.00	Mus musculus	NNGCCYBVGG	CCBVRGGCNN	PBM Badis et al.(2009) Tcfap2e_3713	0.974	0.974
Tfap2b M00112_2.00	Mus musculus	CCBSRGGSNW	WNSCCYSVGG	PBM Badis et al.(2009) Tcfap2b_3988	0.872	0.872
TFAP2B M02753_2.00	Homo sapiens	HSCCYBVRGGCD	HGCCYBVRGGSD	SELEX Jolma et al.(2013) TFAP2B_1	0.872	0.872
TFAP2B M02754_2.00	Homo sapiens	HGCCTSRGGCD	HGCCYSAGGCD	SELEX Jolma et al.(2013) TFAP2B_2	0.872	0.872
TFAP2B M02755_2.00	Homo sapiens	WGCCCYBVRGGCD	HGCCYBVRGGGCW	SELEX Jolma et al.(2013) TFAP2B_3	0.872	0.872
TFAP2B M04046_2.00	Homo sapiens	NSCCBNVGGSN	NSCCBNVGGSN	SELEX Yin et al.(2017) TFAP2B_eDBD_HT-SELEX	0.872	0.872
TFAP2B M08701_2.00	Homo sapiens	GSCYGVGGRV	BYCCBCRGSC	Misc Kulakovskiy et al.(2013) AP2B_HUMAN.H11MO.0.B	0.872	0.872
Tfap2b M08705_2.00	Mus musculus	GSCYGVGGRV	BYCCBCRGSC	Misc Kulakovskiy et al.(2013) AP2B_MOUSE.H11MO.0.B	0.872	0.872
TFAP2B M09750_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$AP2BETA_Q3	0.872	0.872
TFAP2B M04047_2.00	Homo sapiens	NSCCYNRGGSD	HSCCYNRGGSN	SELEX Yin et al.(2017) TFAP2B_eDBD_Methyl-HT-SELEX	0.872	0.872
Tfap2a M00111_2.00	Mus musculus	HSCCBNVRGS	SCYBNVGGSD	PBM Badis et al.(2009) Tcfap2a_2337	0.846	0.846
TFAP2A M02762_2.00	Homo sapiens	HGCCYBVRGGSD	HSCCYBVRGGCD	SELEX Jolma et al.(2013) TFAP2A_1	0.846	0.846
TFAP2A M02763_2.00	Homo sapiens	HGCCYSMGGCN	NGCCKSRGGCD	SELEX Jolma et al.(2013) TFAP2A_2	0.846	0.846
TFAP2A M02764_2.00	Homo sapiens	NSCCCBNVRGGSN	NSCCYBNVGGGSN	SELEX Jolma et al.(2013) TFAP2A_3	0.846	0.846
TFAP2A M02765_2.00	Homo sapiens	HGCCTSRGGCD	HGCCYSAGGCD	SELEX Jolma et al.(2013) TFAP2A_4	0.846	0.846
TFAP2A M02766_2.00	Homo sapiens	HGCCYBVRGGCD	HGCCYBVRGGCD	SELEX Jolma et al.(2013) TFAP2A_5	0.846	0.846
TFAP2A M02767_2.00	Homo sapiens	WGCCCYNVGGGCD	HGCCCBNRGGGCW	SELEX Jolma et al.(2013) TFAP2A_6	0.846	0.846
Tfap2a M02768_2.00	Mus musculus	HGCCYBVRGGCR	YGCCYBVRGGCD	SELEX Jolma et al.(2013) Tcfap2a_1	0.846	0.846
Tfap2a M02769_2.00	Mus musculus	HGCCTSRGGCD	HGCCYSAGGCD	SELEX Jolma et al.(2013) Tcfap2a_2	0.846	0.846
Tfap2a M02770_2.00	Mus musculus	WGCCCYBVGGGCD	HGCCCBVRGGGCW	SELEX Jolma et al.(2013) Tcfap2a_3	0.846	0.846
TFAP2A M04054_2.00	Homo sapiens	NGCCBSVGGCN	NGCCBSVGGCN	SELEX Yin et al.(2017) TFAP2A_FL_HT-SELEX	0.846	0.846
TFAP2A M07784_2.00	Homo sapiens	NBNSCCYSRGGSCWN	NWGSCCYSRGGSNVN	ChIP-seq Gerstein et al.(2012) HeLa-S3_AP2ALPHA_UCD	0.846	0.846
TFAP2A M08703_2.00	Homo sapiens	NHDSCCYCAGGSHWN	NWDSCCTGRGGSHDN	Misc Kulakovskiy et al.(2013) AP2A_HUMAN.H11MO.0.A	0.846	0.846
Tfap2a M08704_2.00	Mus musculus	SCCYCRGGSNNN	NNNSCCYGRGGS	Misc Kulakovskiy et al.(2013) AP2A_MOUSE.H11MO.0.A	0.846	0.846
TFAP2A M09755_2.00	Homo sapiens	GCCBBVVGS	SCBBVVGGC	Transfac Matys et al.(2006) V$AP2ALPHA_01	0.846	0.846
TFAP2A M09756_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$AP2ALPHA_02	0.846	0.846
TFAP2A M09757_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$AP2ALPHA_03	0.846	0.846
TFAP2A M09758_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$AP2ALPHA_Q4	0.846	0.846
TFAP2A M09759_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$AP2ALPHA_Q6	0.846	0.846
TFAP2A M09760_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$TFAP2A_09	0.846	0.846
TFAP2A M04055_2.00	Homo sapiens	NSCCTNAGGSN	NSCCTNAGGSN	SELEX Yin et al.(2017) TFAP2A_FL_Methyl-HT-SELEX	0.846	0.846
Tfap2c M00113_2.00	Mus musculus	NSCCBBVGGS	SCCBVVGGSN	PBM Badis et al.(2009) Tcfap2c_2912	0.774	0.774
Tfap2c M08706_2.00	Mus musculus	NNSCCYGRGGSNN	NNSCCYCRGGSNN	Misc Kulakovskiy et al.(2013) AP2C_MOUSE.H11MO.0.A	0.774	0.774
TFAP2C M02756_2.00	Homo sapiens	HSCCYBVRGGCD	HGCCYBVRGGSD	SELEX Jolma et al.(2013) TFAP2C_1	0.749	0.749
TFAP2C M02757_2.00	Homo sapiens	HGCCTBRGGCD	HGCCYVAGGCD	SELEX Jolma et al.(2013) TFAP2C_2	0.749	0.749
TFAP2C M02758_2.00	Homo sapiens	WGCCCYNRGGGCD	HGCCCYNRGGGCW	SELEX Jolma et al.(2013) TFAP2C_3	0.749	0.749
TFAP2C M02759_2.00	Homo sapiens	HSCCYBVRGGCD	HGCCYBVRGGSD	SELEX Jolma et al.(2013) TFAP2C_4	0.749	0.749
TFAP2C M02760_2.00	Homo sapiens	NGCCCBNVRGGCN	NGCCYBNVGGGCN	SELEX Jolma et al.(2013) TFAP2C_5	0.749	0.749
TFAP2C M02761_2.00	Homo sapiens	HGCCTBRGGCD	HGCCYVAGGCD	SELEX Jolma et al.(2013) TFAP2C_6	0.749	0.749
TFAP2C M04048_2.00	Homo sapiens	NSCYHNHRGBN	NVCYDNDRGSN	SELEX Yin et al.(2017) TFAP2C_eDBD_HT-SELEX	0.749	0.749
TFAP2C M07783_2.00	Homo sapiens	NSCCYSRGGSCANDN	NHNTGSCCYSRGGSN	ChIP-seq Gerstein et al.(2012) HeLa-S3_AP2GAMMA_UCD	0.749	0.749
TFAP2C M08702_2.00	Homo sapiens	NDSCCYCAGGSHHN	NDDSCCTGRGGSHN	Misc Kulakovskiy et al.(2013) AP2C_HUMAN.H11MO.0.A	0.749	0.749
TFAP2C M09451_2.00	Homo sapiens	SCCYSRGGSHNN	NNDSCCYSRGGS	Misc Heinz et al.(2010) MCF7-TFAP2C_GSE21234	0.749	0.749
TFAP2C M09751_2.00	Homo sapiens	GCCBBVRGS	SCYBVVGGC	Transfac Matys et al.(2006) V$AP2GAMMA_01	0.749	0.749
TFAP2C M09752_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$AP2GAMMA_Q4	0.749	0.749
TFAP2C M09753_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$AP2GAMMA_Q5_01	0.749	0.749
TFAP2C M09754_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$AP2GAMMA_Q5	0.749	0.749
TFAP2C M04049_2.00	Homo sapiens	NSCCYNRGGSN	NSCCYNRGGSN	SELEX Yin et al.(2017) TFAP2C_eDBD_Methyl-HT-SELEX	0.749	0.749
AP-2 M03584_2.00	Drosophila melanogaster	HGCCYSRGGCD	HGCCYSRGGCD	SELEX Nitta et al.(2015) AP-2_1	0.703	0.703
AP-2 M03585_2.00	Drosophila melanogaster	HGCCYBVRGGCD	HGCCYBVRGGCD	SELEX Nitta et al.(2015) AP-2_2	0.703	0.703
AP-2 M03586_2.00	Drosophila melanogaster	NSCCYBNVRGGCN	NGCCYBNVRGGSN	SELEX Nitta et al.(2015) AP-2_3	0.703	0.703
AP-2 M03587_2.00	Drosophila melanogaster	HGCCYNRGGCD	HGCCYNRGGCD	SELEX Nitta et al.(2015) AP-2_4	0.703	0.703
AP-2 M03588_2.00	Drosophila melanogaster	HSCCYBVRGGSD	HSCCYBVRGGSD	SELEX Nitta et al.(2015) AP-2_5	0.703	0.703
AP-2 M03589_2.00	Drosophila melanogaster	HGCCYBNVRGGCD	HGCCYBNVRGGCD	SELEX Nitta et al.(2015) AP-2_6	0.703	0.703
For this family, TFs with SR scores > 0.700* will likely have a similar motif*

DNA Binding Domains

Protein ID	Domain	From	To	Sequence
ENSOCUP00000011355	AP-2	166	368	EVFCSVPGRLSLLSSTSKYKVTVGEVQRRLSPPECLNASLLGGVLRRSRAKSKNGGRCLREQLEKIGLNLPAGRRKAANVTLLTSLVEGEAVHLARDFSYVCETEFPAKAAAEYLCRQHADPGGLHSRKSMLLAAKQICKEFADLMAQDRSPLGNSHPALILEPGVQSCLTHFSLITHGFGGPAICAALTAFQNYLLESLKGL

Links
Other AP-2 family TFs
Other *Oryctolagus cuniculus* TFs

393 Related TFs

Name	Species	Gene ID	Motif Evidence	SR Score	Action
GLIS2	Macaca mulatta	ENSMMUG00000015758	N	0.000
ENSTSYG00000009297	Tarsius syrichta	ENSTSYG00000009297	N	0.000
GH12994	Drosophila grimshawi	FBgn0120472	N	0.000
AALB006187	Anopheles albimanus	AALB006187	N	0.000
AMIN010102	Anopheles minimus	AMIN010102	N	0.000

TFAP2E (Oryctolagus cuniculus) AP-2

TF Information

Directly determined binding motifs

Motifs from related TFs

DNA Binding Domains

Links

393 Related TFs

TFAP2E **(Oryctolagus cuniculus)
AP-2**