CIS-BP Database: Catalog of Inferred Sequence Binding Preferences

TF Information

Mlx *(Mus musculus)* bHLH
Pfam ID	Interpro ID	Gene ID	CIS-BP ID	Sequence source	Animal TF db
PF00010 (HLH)	IPR001092	ENSMUSG00000017801	T035668_2.00	Ensembl (2018-Dec-8)	Link out
Directly determined binding motifs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
Mlx M00752_2.00	Mus musculus	CACGTGNNN	NNNCACGTG	PBM Weirauch et al.(2013) pTH2882	(Direct)	(Direct)
Mlx M01721_2.00	Mus musculus	NCRCGTGNNN	NNNCACGYGN	PBM Weirauch et al.(2014) pTH5070	(Direct)	(Direct)
Mlx M02815_2.00	Mus musculus	RTCACGTGAY	RTCACGTGAY	SELEX Jolma et al.(2013) Mlx_1	(Direct)	(Direct)
Motifs from related TFs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
MLX M02779_2.00	Homo sapiens	RTCACGTGAY	RTCACGTGAY	SELEX Jolma et al.(2013) MLX_1	0.914	1.000
MLX M04080_2.00	Homo sapiens	NCACGTGN	NCACGTGN	SELEX Yin et al.(2017) MLX_eDBD_HT-SELEX	0.914	1.000
MLX M04082_2.00	Homo sapiens	NVCACGTGVYN	NRBCACGTGBN	SELEX Yin et al.(2017) MLX_FL_HT-SELEX	0.914	1.000
MLX M04081_2.00	Homo sapiens	NCACRTGV	BCAYGTGN	SELEX Yin et al.(2017) MLX_eDBD_Methyl-HT-SELEX	0.914	1.000
MLX M04083_2.00	Homo sapiens	NDBCACRTGBV	BVCAYGTGVHN	SELEX Yin et al.(2017) MLX_FL_Methyl-HT-SELEX	0.529	1.000
MLX M01114_2.00	Monodelphis domestica	NNNCACGTGN	NCACGTGNNN	PBM Lambert et al.(2019) pTH11463	0.914	0.982
For this family, TFs with SR scores > 0.838* will likely have a similar motif*

Experimental Constructs

Motif ID	Domain	From	To	Sequence
M00752_2.00	bHLH	130	188	RRRAHTQAEQKRRDAIKRGYDDLQTIVPTCQQQDFSIGSQKLSKAIVLQKTIDYIQFLH
M01721_2.00	bHLH	16	74	RRRAHTQAEQKRRDAIKRGYDDLQTIVPTCQQQDFSIGSQKLSKAIVLQKTIDYIQFLH

DNA Binding Domains

Protein ID	Domain	From	To	Sequence
ENSMUSP00000017945	bHLH	130	188	RRRAHTQAEQKRRDAIKRGYDDLQTIVPTCQQQDFSIGSQKLSKAIVLQKTIDYIQFLH
ENSMUSP00000102923	bHLH	76	134	RRRAHTQAEQKRRDAIKRGYDDLQTIVPTCQQQDFSIGSQKLSKAIVLQKTIDYIQFLH
ENSMUSP00000102924	bHLH	46	104	RRRAHTQAEQKRRDAIKRGYDDLQTIVPTCQQQDFSIGSQKLSKAIVLQKTIDYIQFLH
ENSMUSP00000121600	bHLH	100	127	RRRAHTQAEQKRRDAIKRGYDDLQTIVP

Links
Other bHLH family TFs
Other *Mus musculus* TFs