CREB1 (Homo sapiens)
bZIP

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00170 (bZIP_1) IPR011616 ENSG00000118260 T059734_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
CREB1
M04022_2.00		 Homo sapiens
NRTGACGTCAYN
NRTGACGTCAYN		 SELEX
Rodriguez-Martinez et al.(2017)
CREB1.1		 (Direct) (Direct)
CREB1
M04023_2.00		 Homo sapiens
RTGACGTADB
VHTACGTCAY		 SELEX
Rodriguez-Martinez et al.(2017)
CREB1.2		 (Direct) (Direct)
CREB1
M04258_2.00		 Homo sapiens
NVTKACGTMANN
NNTKACGTMABN		 SELEX
Yin et al.(2017)
CREB1_eDBD_HT-SELEX_1		 (Direct) (Direct)
CREB1
M04259_2.00		 Homo sapiens
NRTGACGTR
YACGTCAYN		 SELEX
Yin et al.(2017)
CREB1_eDBD_HT-SELEX_2		 (Direct) (Direct)
CREB1
M04260_2.00		 Homo sapiens
VTSACRYGWBAY
RTVWCRYGTSAB		 SELEX
Yin et al.(2017)
CREB1_eDBD_HT-SELEX_3		 (Direct) (Direct)
CREB1
M04261_2.00		 Homo sapiens
BRTGAYGYGND
HNCRCRTCAYV		 SELEX
Yin et al.(2017)
CREB1_eDBD_Methyl-HT-SELEX_1		 (Direct) (Direct)
CREB1
M04262_2.00		 Homo sapiens
NRTGACRTCAYN
NRTGAYGTCAYN		 SELEX
Yin et al.(2017)
CREB1_eDBD_Methyl-HT-SELEX_2		 (Direct) (Direct)
CREB1
M04263_2.00		 Homo sapiens
NRTGACGYV
BRCGTCAYN		 SELEX
Yin et al.(2017)
CREB1_eDBD_Methyl-HT-SELEX_3		 (Direct) (Direct)
CREB1
M04264_2.00		 Homo sapiens
NVTKACGTMABN
NVTKACGTMABN		 SELEX
Yin et al.(2017)
CREB1_FL_HT-SELEX		 (Direct) (Direct)
CREB1
M04265_2.00		 Homo sapiens
NRTGACRTCAYN
NRTGAYGTCAYN		 SELEX
Yin et al.(2017)
CREB1_FL_Methyl-HT-SELEX		 (Direct) (Direct)
CREB1
M08066_2.00		 Homo sapiens
NVTGACGTCABN
NVTGACGTCABN		 ChIP-seq
Mathelier et al.(2014)
MA0018.3		 (Direct) (Direct)
CREB1
M08791_2.00		 Homo sapiens
WKRCGTCAYYN
NRRTGACGYMW		 Misc
Kulakovskiy et al.(2013)
CREB1_HUMAN.H11MO.0.A		 (Direct) (Direct)
CREB1
M09948_2.00		 Homo sapiens
TGACGTMW
WKACGTCA		 Transfac
Matys et al.(2006)
V$CREB_01		 (Direct) (Direct)
CREB1
M09949_2.00		 Homo sapiens
BBGDTGACGYVV
BBRCGTCAHCVV		 Transfac
Matys et al.(2006)
V$CREB_02		 (Direct) (Direct)
CREB1
M09950_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$CREB1_Q3		 (Direct) (Direct)
CREB1
M09951_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$CREB1_Q6		 (Direct) (Direct)
CREB1
M09952_2.00		 Homo sapiens
BSTGACGYARNN
NNYTRCGTCASV		 Transfac
Matys et al.(2006)
V$CREB_Q2		 (Direct) (Direct)
CREB1
M09953_2.00		 Homo sapiens
BSTGACGYMRBV
BVYKRCGTCASV		 Transfac
Matys et al.(2006)
V$CREB_Q4		 (Direct) (Direct)
CREB1
M09954_2.00		 Homo sapiens
KKGGGKTGACGYMND
HNKRCGTCAMCCCMM		 Transfac
Matys et al.(2006)
V$TAXCREB_01		 (Direct) (Direct)
CREB1
M09955_2.00		 Homo sapiens
RTGACGCATAYCCCC
GGGGRTATGCGTCAY		 Transfac
Matys et al.(2006)
V$TAXCREB_02		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Creb1
M00992_2.00 		Mus musculus
NNTGACGTCV
BGACGTCANN		 PBM
Mann et al.(2013)
CREB1_UM_HK 		0.715 1.000
Creb1
M01806_2.00 		Mus musculus
VTKACGHNN
NNDCGTMAB		 PBM
Weirauch et al.(2014)
pTH5080 		0.904 1.000
Creb1
M08824_2.00 		Mus musculus
WKRCGTCAYYN
NRRTGACGYMW		 Misc
Kulakovskiy et al.(2013)
CREB1_MOUSE.H11MO.0.A 		0.904 1.000
Creb1
M00991_2.00 		Mus musculus
NNRTGACGYVN
NBRCGTCAYNN		 PBM
Mann et al.(2013)
CREB1_M_HK 		0.904 1.000
ATF1
M08792_2.00 		Homo sapiens
HBRCGTCAYHN
NDRTGACGYVD		 Misc
Kulakovskiy et al.(2013)
ATF1_HUMAN.H11MO.0.B 		0.894 0.867
ATF1
M09485_2.00 		Homo sapiens
NVTGACGTMA
TKACGTCABN		 Misc
Heinz et al.(2010)
K562-ATF1_GSE31477 		0.894 0.867
ATF1
M09956_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$ATF1_Q3 		0.894 0.867
ATF1
M09957_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$ATF1_Q6_01 		0.894 0.867
ATF1
M09958_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$ATF1_Q6 		0.894 0.867
Atf1
M00124_2.00 		Mus musculus
NNNNDNDNNN
NNNHNHNNNN		 PBM
Badis et al.(2009)
Atf1_3026 		0.883 0.867
Atf1
M01804_2.00 		Mus musculus
RTGACGTV
BACGTCAY		 PBM
Weirauch et al.(2014)
pTH5005 		0.883 0.867
Atf1
M08820_2.00 		Mus musculus
VTGACGTSAV
BTSACGTCAB		 Misc
Kulakovskiy et al.(2013)
ATF1_MOUSE.H11MO.0.B 		0.883 0.867
Crem
M01821_2.00 		Mus musculus
NRTKACGTMN
NKACGTMAYN		 PBM
Weirauch et al.(2014)
pTH5002 		0.882 0.950
Crem
M08845_2.00 		Mus musculus
SVVTGACGTSA
TSACGTCABBS		 Misc
Kulakovskiy et al.(2013)
CREM_MOUSE.H11MO.0.C 		0.882 0.950
CREM
M04229_2.00 		Homo sapiens
VVTBACGTVABN
NVTBACGTVABB		 SELEX
Yin et al.(2017)
CREM_eDBD_HT-SELEX 		0.851 0.767
CREM
M08784_2.00 		Homo sapiens
SVVTGACGTSA
TSACGTCABBS		 Misc
Kulakovskiy et al.(2013)
CREM_HUMAN.H11MO.0.C 		0.851 0.767
CREM
M09930_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$CREM_Q6_01 		0.851 0.767
CREM
M09931_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$CREM_Q6 		0.851 0.767
CREM
M04230_2.00 		Homo sapiens
NRTGACRTCAYN
NRTGAYGTCAYN		 SELEX
Yin et al.(2017)
CREM_eDBD_Methyl-HT-SELEX 		0.851 0.767
CrebB-17A
M03659_2.00 		Drosophila melanogaster
RTGACGTCAY
RTGACGTCAY		 SELEX
Nitta et al.(2015)
CrebB-17A_1 		0.819 0.800
CrebB-17A
M03660_2.00 		Drosophila melanogaster
RTGACGTCAY
RTGACGTCAY		 SELEX
Nitta et al.(2015)
CrebB-17A_2 		0.819 0.800
For this family, TFs with SR scores > 0.782 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000236995 bZIP 267 326
ENSP00000387699 bZIP 281 340
ENSP00000405539 bZIP 267 326
ENSP00000405711 bZIP 227 251

Links

Other bZIP family TFs
Other Homo sapiens TFs

361 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
Atf3 Drosophila melanogaster FBgn0028550 D
ACUA018111 Anopheles culicifacies ACUA018111 I
SINV20083 Solenopsis invicta SINV20083 I
TC008201 Tribolium castaneum TC008201 I
YQE_04190 Dendroctonus ponderosae YQE_04190 I
Cflo_05052--XP_392513.1_APIME Camponotus floridanus Cflo_05052--XP_392513.1_APIME I
Hsal_14793--XP_392513.1_APIME Harpegnathos saltator Hsal_14793--XP_392513.1_APIME I
CLEC002857 Cimex lectularius CLEC002857 I
LCUP009590 Lucilia cuprina LCUP009590 I
LDEC018714 Leptinotarsa decemlineata LDEC018714 I
AALB009141 Anopheles albimanus AALB009141 I
AARA001983 Anopheles arabiensis AARA001983 I
AATE020966 Anopheles atroparvus AATE020966 I
RPRC001561 Rhodnius prolixus RPRC001561 I
ADIR009888 Anopheles dirus ADIR009888 I
AEPI006169 Anopheles epiroticus AEPI006169 I
AFAF020202 Anopheles farauti AFAF020202 I
AFUN001209 Anopheles funestus AFUN001209 I
AMEC005345 Anopheles melas AMEC005345 I
AMEM000126 Anopheles merus AMEM000126 I
AMIN002428 Anopheles minimus AMIN002428 I
ASIS002535 Anopheles sinensis ASIS002535 I
ASTEI05449 Anopheles stephensi ASTEI05449 I
MDOA009377 Musca domestica MDOA009377 I
GD16430 Drosophila simulans FBgn0188046 I
AAEL009442 Aedes aegypti AAEL009442 I
ACYPI32234 Acyrthosiphon pisum ACYPI32234 I
CPIJ001204 Culex quinquefasciatus CPIJ001204 I
ENSPMAG00000006157 Petromyzon marinus ENSPMAG00000006157 I
GA10981 Drosophila pseudoobscura FBgn0071037 I
GG12710 Drosophila erecta FBgn0104997 I
GH24925 Drosophila grimshawi FBgn0132380 I
GI21781 Drosophila mojavensis FBgn0144511 I
GL14394 Drosophila persimilis FBgn0151999 I
GM18988 Drosophila sechellia FBgn0173891 I
CpipJ_CPIJ001204 Culex pipiens CpipJ_CPIJ001204 I
GJ16954 Drosophila virilis FBgn0204132 I
GK19912 Drosophila willistoni FBgn0221909 I
GE16537 Drosophila yakuba FBgn0234052 I
GB53401 Apis mellifera GB53401 I
HMEL006570 Heliconius melpomene HMEL006570 I
KGM_03513 Danaus plexippus KGM_03513 I
L798_12793 Zootermopsis nevadensis L798_12793 I
MCINX010628 Melitaea cinxia MCINX010628 I
NV16727 Nasonia vitripennis NV16727 I
PHUM288370 Pediculus humanus PHUM288370 I