NFE2 (Homo sapiens)
bZIP

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00170 (bZIP_1) IPR011616 ENSG00000123405 T059736_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
NFE2
M02832_2.00		 Homo sapiens
VATGACTCATB
VATGAGTCATB		 SELEX
Jolma et al.(2013)
NFE2_1		 (Direct) (Direct)
NFE2
M04024_2.00		 Homo sapiens
RTGACTCAY
RTGAGTCAY		 SELEX
Rodriguez-Martinez et al.(2017)
NFE2.1		 (Direct) (Direct)
NFE2
M04266_2.00		 Homo sapiens
VRTGASTCAYB
VRTGASTCAYB		 SELEX
Yin et al.(2017)
NFE2_eDBD_HT-SELEX		 (Direct) (Direct)
NFE2
M04267_2.00		 Homo sapiens
NRTGASTCAYN
NRTGASTCAYN		 SELEX
Yin et al.(2017)
NFE2_eDBD_Methyl-HT-SELEX		 (Direct) (Direct)
NFE2
M07813_2.00		 Homo sapiens
VRTGACTCAGCANWWHB
VDWWNTGCTGAGTCAYB		 ChIP-seq
Gerstein et al.(2012)
K562_NFE2_Stanford		 (Direct) (Direct)
NFE2
M08793_2.00		 Homo sapiens
VVRTGACTCAGCA
TGCTGAGTCAYBB		 Misc
Kulakovskiy et al.(2013)
NFE2_HUMAN.H11MO.0.A		 (Direct) (Direct)
NFE2
M09486_2.00		 Homo sapiens
VATGACTCAGCA
TGCTGAGTCATB		 Misc
Heinz et al.(2010)
K562-NFE2_GSE31477		 (Direct) (Direct)
NFE2
M09959_2.00		 Homo sapiens
RTGASTCAGCD
HGCTGASTCAY		 Transfac
Matys et al.(2006)
V$NFE2_01		 (Direct) (Direct)
NFE2
M09960_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NFE2_04		 (Direct) (Direct)
NFE2
M09961_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NFE2_Q6		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Nfe2
M08843_2.00 		Mus musculus
RTGACTCAGCANDW
WHNTGCTGAGTCAY		 Misc
Kulakovskiy et al.(2013)
NFE2_MOUSE.H11MO.0.A 		0.915 0.952
NFE2L2
M01142_2.00 		Gallus gallus
NNRTKAYNN
NNRTMAYNN		 PBM
Lambert et al.(2019)
pTH9845 		0.868 0.683
NFE2L2
M08789_2.00 		Homo sapiens
RTGACTCAGCANWW
WWNTGCTGAGTCAY		 Misc
Kulakovskiy et al.(2013)
NF2L2_HUMAN.H11MO.0.A 		0.868 0.635
NFE2L2
M09943_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NRF2_Q3 		0.868 0.635
NFE2L2
M09944_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NRF2_Q4_01 		0.868 0.635
NFE2L2
M09945_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NRF2_Q4 		0.868 0.635
NFE2L2
M09946_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NRF2_Q6 		0.868 0.635
Nfe2l2
M08077_2.00 		Mus musculus
NRNNRTGACTCAGCA
TGCTGAGTCAYNNYN		 ChIP-seq
Mathelier et al.(2014)
MA0150.2 		0.858 0.667
Nfe2l2
M08816_2.00 		Mus musculus
RTGACTNAGCANDH
DHNTGCTNAGTCAY		 Misc
Kulakovskiy et al.(2013)
NF2L2_MOUSE.H11MO.0.A 		0.858 0.667
NFE2L1
M04008_2.00 		Homo sapiens
RTGACTCAY
RTGAGTCAY		 SELEX
Rodriguez-Martinez et al.(2017)
NFE2L1.1 		0.832 0.587
NFE2L1
M08782_2.00 		Homo sapiens
NATGAYD
HRTCATN		 Misc
Kulakovskiy et al.(2013)
NF2L1_HUMAN.H11MO.0.C 		0.832 0.587
Nfe2l1
M08831_2.00 		Mus musculus
NATGAYD
HRTCATN		 Misc
Kulakovskiy et al.(2013)
NF2L1_MOUSE.H11MO.0.C 		0.832 0.587
NFE2L1
M09925_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NFE2L1_Q5 		0.832 0.587
NFE2L1
M09926_2.00 		Homo sapiens
NNNNHWNNATGAC
GTCATNNWDNNNN		 Transfac
Matys et al.(2006)
V$TCF11_01 		0.832 0.587
Nfe2l3
M10031_2.00 		Mus musculus Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NRF3_01 		0.828 0.508
NFE2L3
M09923_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NRF3_02 		0.815 0.508
FBgn0262975
M03654_2.00 		Drosophila melanogaster
NYGTCAYSRTGACRN
NYGTCAYSRTGACRN		 SELEX
Nitta et al.(2015)
cnc_1 		0.791 0.444
FBgn0262975
M03655_2.00 		Drosophila melanogaster
SATGACRNVVATGACD
HGTCATBBNYGTCATS		 SELEX
Nitta et al.(2015)
cnc_2 		0.791 0.444
FBgn0262975
M03656_2.00 		Drosophila melanogaster
GTCAKSATGACGTCAY
RTGACGTCATSMTGAC		 SELEX
Nitta et al.(2015)
cnc_3 		0.791 0.444
FBgn0262975
M08189_2.00 		Drosophila melanogaster
TGAYTBDGCA
TGCHVARTCA		 ChIP-seq
Contrino et al.(2012)
Mf3 		0.791 0.444
For this family, TFs with SR scores > 0.782 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000312436 bZIP 265 327
ENSP00000397185 bZIP 265 327
ENSP00000439120 bZIP 265 327
ENSP00000446929 bZIP 265 327
ENSP00000447558 bZIP 265 327

Links

Other bZIP family TFs
Other Homo sapiens TFs

328 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ZHX3 Taeniopygia guttata ENSTGUG00000004817 N 0.000
ENSNLEG00000006488 Nomascus leucogenys ENSNLEG00000006488 N 0.000
ZHX3 Ornithorhynchus anatinus ENSOANG00000014351 N 0.000
ZHX3 Oryctolagus cuniculus ENSOCUG00000006439 N 0.000
ZHX3 Otolemur garnettii ENSOGAG00000013363 N 0.000
ZHX3 Ochotona princeps ENSOPRG00000014931 N 0.000
ENSPANG00000023855 Papio anubis ENSPANG00000023855 N 0.000
ENSPPYG00000011012 Pongo abelii ENSPPYG00000011012 N 0.000
ENSPSIG00000010741 Pelodiscus sinensis ENSPSIG00000010741 N 0.000
ZHX3 Pan troglodytes ENSPTRG00000013501 N 0.000
Zhx3 Rattus norvegicus ENSRNOG00000027988 N 0.000
ZHX3 Sorex araneus ENSSARG00000005424 N 0.000
ENSSTOG00000011674 Ictidomys tridecemlineatus ENSSTOG00000011674 N 0.000
Zhx3 Mus musculus ENSMUSG00000035877 N 0.000
ZHX3 Tursiops truncatus ENSTTRG00000002687 N 0.000
Aan_R003309 Calypte anna Aan_R003309 N 0.000
Afo_R009777 Aptenodytes forsteri Afo_R009777 N 0.000
Alligator_sinensis_CCG018823.1 Alligator sinensis Alligator_sinensis_CCG018823.1 N 0.000
Cmyd_10015207 Chelonia mydas Cmyd_10015207 N 0.000
ENSMMUP00000037938 Macaca fascicularis ENSMMUP00000037938 N 0.000
ENSP00000380144-D1 Bos grunniens ENSP00000380144-D1 N 0.000
Gfo_R005414 Geospiza fortis Gfo_R005414 N 0.000
Myotis_brandtii_ZHX3_10025211 Myotis brandtii Myotis_brandtii_ZHX3_10025211 N 0.000
Ogr10588 Ophisaurus gracilis Ogr10588 N 0.000
Pvit_08734 Pogona vitticeps Pvit_08734 N 0.000
ENSFALG00000005566 Ficedula albicollis ENSFALG00000005566 N 0.000
ENSAMEG00000009571 Ailuropoda melanoleuca ENSAMEG00000009571 N 0.000
ENSAPLG00000006697 Anas platyrhynchos ENSAPLG00000006697 N 0.000
ZHX3 Bos taurus ENSBTAG00000017594 N 0.000
ZHX3 Canis familiaris ENSCAFG00000009101 N 0.000
ZHX3 Choloepus hoffmanni ENSCHOG00000009000 N 0.000
ZHX3 Callithrix jacchus ENSCJAG00000018012 N 0.000
ZHX3 Cavia porcellus ENSCPOG00000002738 N 0.000
ENSCSAG00000013961 Chlorocebus sabaeus ENSCSAG00000013961 N 0.000
ZHX3 Dasypus novemcinctus ENSDNOG00000005387 N 0.000
Zhx3 Dipodomys ordii ENSDORG00000012139 N 0.000
ZHX3 Echinops telfairi ENSETEG00000005517 N 0.000
ZHX3 Anolis carolinensis ENSACAG00000011460 N 0.000
ZHX3 Felis catus ENSFCAG00000009034 N 0.000
ZHX3 Homo sapiens ENSG00000174306 N 0.000
ENSGALG00000027603 Gallus gallus ENSGALG00000027603 N 0.000
ZHX3 Gorilla gorilla ENSGGOG00000008691 N 0.000
ENSLACG00000019016 Latimeria chalumnae ENSLACG00000019016 N 0.000
ZHX3 Loxodonta africana ENSLAFG00000022196 N 0.000
ENSLOCG00000004596 Lepisosteus oculatus ENSLOCG00000004596 N 0.000
ZHX3 Myotis lucifugus ENSMLUG00000010226 N 0.000
ZHX3 Macaca mulatta ENSMMUG00000005904 N 0.000
ZHX3 Monodelphis domestica ENSMODG00000000636 N 0.000
ENSMPUG00000017699 Mustela putorius furo ENSMPUG00000017699 N 0.000