ZNF516 (Gorilla gorilla)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSGGOG00000003996 T096144_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No TFs with similar DNA binding domains

DNA Binding Domains

Protein ID Domain From To Sequence
ENSGGOP00000003922 C2H2 ZF 32 56
ENSGGOP00000003922 C2H2 ZF 62 84
ENSGGOP00000003922 C2H2 ZF 200 223
ENSGGOP00000003922 C2H2 ZF 248 270
ENSGGOP00000003922 C2H2 ZF 278 298
ENSGGOP00000003922 C2H2 ZF 336 357

Links

Other C2H2 ZF family TFs
Other Gorilla gorilla TFs

8 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
FOXK2 Homo sapiens ENSG00000141568 D
FOXK1 Homo sapiens ENSG00000164916 D
FOXI1 Homo sapiens ENSG00000168269 D
Foxi1 Mus musculus ENSMUSG00000047861 D
Foxk1 Mus musculus ENSMUSG00000056493 D
SPU_025010 Strongylocentrotus purpuratus SPU_025010 D
CAOG_05750 Capsaspora owczarzaki CAOG_05750 I
CpipJ_CPIJ003766 Culex pipiens CpipJ_CPIJ003766 I
AAEL008958 Aedes aegypti AAEL008958 I
ACEP17652 Atta cephalotes ACEP17652 I
ACYPI006817 Acyrthosiphon pisum ACYPI006817 I
ADAC001846 Anopheles darlingi ADAC001846 I
AGAP000662 Anopheles gambiae AGAP000662 I
AGAP005804 Anopheles gambiae AGAP005804 I
CapteG23732 Capitella teleta CapteG23732 I
CGI_10026255 Crassostrea gigas CGI_10026255 I
CPIJ003766 Culex quinquefasciatus CPIJ003766 I
DAPPUDRAFT_332896 Daphnia pulex DAPPUDRAFT_332896 I
EFV50646 Trichinella spiralis EFV50646 I
FOXI1 Anolis carolinensis ENSACAG00000015950 I
FOXK2 Anolis carolinensis ENSACAG00000017333 I
FOXK1 Anolis carolinensis ENSACAG00000017542 I
ENSAMEG00000001235 Ailuropoda melanoleuca ENSAMEG00000001235 I
ENSAMEG00000001516 Ailuropoda melanoleuca ENSAMEG00000001516 I
ENSAMEG00000006428 Ailuropoda melanoleuca ENSAMEG00000006428 I
ENSAMXG00000006509 Astyanax mexicanus ENSAMXG00000006509 I
ENSAMXG00000008393 Astyanax mexicanus ENSAMXG00000008393 I
ENSAMXG00000009961 Astyanax mexicanus ENSAMXG00000009961 I
ENSAMXG00000012362 Astyanax mexicanus ENSAMXG00000012362 I
ENSAMXG00000015672 Astyanax mexicanus ENSAMXG00000015672 I
ENSAPLG00000007723 Anas platyrhynchos ENSAPLG00000007723 I
ENSAPLG00000009084 Anas platyrhynchos ENSAPLG00000009084 I
FOXI1 Bos taurus ENSBTAG00000014620 I
FOXK1 Bos taurus ENSBTAG00000019310 I
FOXK2 Canis familiaris ENSCAFG00000012985 I
FOXK1 Canis familiaris ENSCAFG00000016111 I
FOXI1 Canis familiaris ENSCAFG00000016968 I
FOXK2 Choloepus hoffmanni ENSCHOG00000005344 I
foxk Ciona intestinalis ENSCING00000006184 I
foxp Ciona intestinalis ENSCING00000012009 I
FOXI1 Callithrix jacchus ENSCJAG00000011646 I
FOXK2 Callithrix jacchus ENSCJAG00000017923 I
FOXK1 Callithrix jacchus ENSCJAG00000018682 I
FOXK1 Cavia porcellus ENSCPOG00000014118 I
ENSCSAG00000002109 Chlorocebus sabaeus ENSCSAG00000002109 I
ENSCSAG00000010076 Chlorocebus sabaeus ENSCSAG00000010076 I
ENSCSAG00000017639 Chlorocebus sabaeus ENSCSAG00000017639 I
ENSCSAVG00000001390 Ciona savignyi ENSCSAVG00000001390 I
ENSCSAVG00000009468 Ciona savignyi ENSCSAVG00000009468 I
FOXK2 Danio rerio ENSDARG00000011609 I
foxk2 Danio rerio ENSDARG00000030583 I
foxk1 Danio rerio ENSDARG00000037872 I
FOXK1 Dasypus novemcinctus ENSDNOG00000001048 I
FOXI1 Dasypus novemcinctus ENSDNOG00000007480 I
FOXK2 Dasypus novemcinctus ENSDNOG00000039491 I
FOXK1 Equus caballus ENSECAG00000015133 I
FOXK2 Equus caballus ENSECAG00000020989 I
ENSEEUG00000015756 Erinaceus europaeus ENSEEUG00000015756 I
FOXK2 Echinops telfairi ENSETEG00000007437 I
ENSFALG00000000785 Ficedula albicollis ENSFALG00000000785 I
ENSFALG00000009556 Ficedula albicollis ENSFALG00000009556 I
ENSFALG00000013841 Ficedula albicollis ENSFALG00000013841 I
FOXI1 Felis catus ENSFCAG00000000835 I
ENSFCAG00000002315 Felis catus ENSFCAG00000002315 I
FOXK1 Felis catus ENSFCAG00000009982 I
foxk2 Gasterosteus aculeatus ENSGACG00000014443 I
FOXK2 Gasterosteus aculeatus ENSGACG00000015190 I
foxk1 Gasterosteus aculeatus ENSGACG00000016666 I
foxi3a Gasterosteus aculeatus ENSGACG00000018474 I
FOXK2 Gallus gallus ENSGALG00000001577 I
FOXK1 Gallus gallus ENSGALG00000004460 I
ENSGGOG00000002679 Gorilla gorilla ENSGGOG00000002679 I
FOXK2 Gorilla gorilla ENSGGOG00000006120 I
FOXI1 Gorilla gorilla ENSGGOG00000015780 I
ENSGMOG00000001605 Gadus morhua ENSGMOG00000001605 I
ENSGMOG00000001944 Gadus morhua ENSGMOG00000001944 I
ENSGMOG00000002370 Gadus morhua ENSGMOG00000002370 I
ENSGMOG00000007781 Gadus morhua ENSGMOG00000007781 I
ENSLACG00000002970 Latimeria chalumnae ENSLACG00000002970 I
ENSLACG00000003779 Latimeria chalumnae ENSLACG00000003779 I
ENSLACG00000017904 Latimeria chalumnae ENSLACG00000017904 I
FOXK1 Loxodonta africana ENSLAFG00000003036 I
FOXK2 Loxodonta africana ENSLAFG00000008867 I
FOXI1 Loxodonta africana ENSLAFG00000026591 I
ENSLOCG00000004430 Lepisosteus oculatus ENSLOCG00000004430 I
ENSLOCG00000012201 Lepisosteus oculatus ENSLOCG00000012201 I
ENSMEUG00000000316 Macropus eugenii ENSMEUG00000000316 I
ENSMEUG00000012219 Macropus eugenii ENSMEUG00000012219 I
ENSMEUG00000012884 Macropus eugenii ENSMEUG00000012884 I
ENSMEUG00000013467 Macropus eugenii ENSMEUG00000013467 I
FOXK1 Meleagris gallopavo ENSMGAG00000003278 I
FOXK2 Meleagris gallopavo ENSMGAG00000003743 I
FOXK2 Microcebus murinus ENSMICG00000004568 I
FOXK1 Microcebus murinus ENSMICG00000008124 I
FOXI1 Microcebus murinus ENSMICG00000012575 I
FOXK2 Myotis lucifugus ENSMLUG00000000903 I
FOXK1 Myotis lucifugus ENSMLUG00000010254 I
FOXI1 Myotis lucifugus ENSMLUG00000027832 I
FOXK2 Macaca mulatta ENSMMUG00000009129 I
FOXK1 Macaca mulatta ENSMMUG00000011227 I
FOXI1 Macaca mulatta ENSMMUG00000014124 I
FOXK1 Monodelphis domestica ENSMODG00000000866 I
FOXI1 Monodelphis domestica ENSMODG00000006890 I
ENSMODG00000007231 Monodelphis domestica ENSMODG00000007231 I
ENSMPUG00000010920 Mustela putorius furo ENSMPUG00000010920 I
ENSMPUG00000012982 Mustela putorius furo ENSMPUG00000012982 I
ENSMPUG00000016655 Mustela putorius furo ENSMPUG00000016655 I
Foxk2 Mus musculus ENSMUSG00000039275 I
ENSNLEG00000005109 Nomascus leucogenys ENSNLEG00000005109 I
ENSNLEG00000010504 Nomascus leucogenys ENSNLEG00000010504 I
ENSNLEG00000015459 Nomascus leucogenys ENSNLEG00000015459 I
FOXK1 Ornithorhynchus anatinus ENSOANG00000003307 I
ENSOANG00000012578 Ornithorhynchus anatinus ENSOANG00000012578 I
ENSOARG00000003151 Ovis aries ENSOARG00000003151 I
ENSOARG00000003652 Ovis aries ENSOARG00000003652 I
ENSOARG00000016414 Ovis aries ENSOARG00000016414 I
FOXI1 Oryctolagus cuniculus ENSOCUG00000000836 I
FOXK1 Oryctolagus cuniculus ENSOCUG00000004344 I
FOXK2 Oryctolagus cuniculus ENSOCUG00000016861 I
ENSOCUG00000027107 Oryctolagus cuniculus ENSOCUG00000027107 I
FOXK2 Otolemur garnettii ENSOGAG00000005053 I
FOXK1 Otolemur garnettii ENSOGAG00000016251 I
FOXI1 Otolemur garnettii ENSOGAG00000032689 I
ENSONIG00000003229 Oreochromis niloticus ENSONIG00000003229 I
ENSONIG00000009564 Oreochromis niloticus ENSONIG00000009564 I
ENSONIG00000017618 Oreochromis niloticus ENSONIG00000017618 I
ENSONIG00000019520 Oreochromis niloticus ENSONIG00000019520 I
FOXK1 Ochotona princeps ENSOPRG00000007443 I
foxk2 Oryzias latipes ENSORLG00000000973 I
foxk1 Oryzias latipes ENSORLG00000009023 I
ENSORLG00000012992 Oryzias latipes ENSORLG00000012992 I
ENSPANG00000013256 Papio anubis ENSPANG00000013256 I
ENSPANG00000018795 Papio anubis ENSPANG00000018795 I
ENSPANG00000019580 Papio anubis ENSPANG00000019580 I
FOXI1 Procavia capensis ENSPCAG00000006657 I
FOXK1 Procavia capensis ENSPCAG00000009350 I
ENSPFOG00000004194 Poecilia formosa ENSPFOG00000004194 I
ENSPFOG00000007970 Poecilia formosa ENSPFOG00000007970 I
ENSPFOG00000015741 Poecilia formosa ENSPFOG00000015741 I
ENSPFOG00000019094 Poecilia formosa ENSPFOG00000019094 I
ENSPMAG00000004814 Petromyzon marinus ENSPMAG00000004814 I
ENSPMAG00000008224 Petromyzon marinus ENSPMAG00000008224 I
ENSPPYG00000008784 Pongo abelii ENSPPYG00000008784 I
ENSPPYG00000016029 Pongo abelii ENSPPYG00000016029 I
ENSPPYG00000017325 Pongo abelii ENSPPYG00000017325 I
ENSPSIG00000010095 Pelodiscus sinensis ENSPSIG00000010095 I
ENSPSIG00000011566 Pelodiscus sinensis ENSPSIG00000011566 I
FOXK2 Pan troglodytes ENSPTRG00000009806 I
FOXI1 Pan troglodytes ENSPTRG00000017514 I
FOXK1 Pan troglodytes ENSPTRG00000018875 I
FOXI1 Pteropus vampyrus ENSPVAG00000005974 I
FOXK1 Pteropus vampyrus ENSPVAG00000009311 I
ENSPVAG00000009383 Pteropus vampyrus ENSPVAG00000009383 I
Foxk1 Rattus norvegicus ENSRNOG00000001104 I
Foxi1 Rattus norvegicus ENSRNOG00000006293 I
Foxk2 Rattus norvegicus ENSRNOG00000036663 I
FOXK2 Sorex araneus ENSSARG00000000033 I
ENSSHAG00000002409 Sarcophilus harrisii ENSSHAG00000002409 I
ENSSHAG00000006003 Sarcophilus harrisii ENSSHAG00000006003 I
ENSSHAG00000017137 Sarcophilus harrisii ENSSHAG00000017137 I
ENSSHAG00000018578 Sarcophilus harrisii ENSSHAG00000018578 I
FOXK1 Sus scrofa ENSSSCG00000007576 I
FOXI1 Sus scrofa ENSSSCG00000017009 I
FOXK2 Sus scrofa ENSSSCG00000017125 I
ENSSTOG00000000564 Ictidomys tridecemlineatus ENSSTOG00000000564 I
ENSSTOG00000003586 Ictidomys tridecemlineatus ENSSTOG00000003586 I
ENSSTOG00000016524 Ictidomys tridecemlineatus ENSSTOG00000016524 I
FOXI1 Tupaia belangeri ENSTBEG00000000162 I
FOXI1 Taeniopygia guttata ENSTGUG00000001568 I
ENSTGUG00000007654 Taeniopygia guttata ENSTGUG00000007654 I
FOXK1 Taeniopygia guttata ENSTGUG00000007783 I
FOXK2 Tetraodon nigroviridis ENSTNIG00000010237 I
foxk2 Tetraodon nigroviridis ENSTNIG00000011273 I
foxi3a Tetraodon nigroviridis ENSTNIG00000017058 I
foxk2 Takifugu rubripes ENSTRUG00000002114 I
FOXK2 Takifugu rubripes ENSTRUG00000003203 I
foxi3a Takifugu rubripes ENSTRUG00000007060 I
foxk1 Takifugu rubripes ENSTRUG00000012135 I
ENSTSYG00000001279 Tarsius syrichta ENSTSYG00000001279 I
FOXI1 Tursiops truncatus ENSTTRG00000002178 I
FOXK1 Tursiops truncatus ENSTTRG00000013048 I
FOXK2 Tursiops truncatus ENSTTRG00000013147 I
ENSXMAG00000010462 Xiphophorus maculatus ENSXMAG00000010462 I
ENSXMAG00000011644 Xiphophorus maculatus ENSXMAG00000011644 I
fd68A Drosophila melanogaster FBgn0036134 I
GG13935 Drosophila erecta FBgn0106198 I
GH14639 Drosophila grimshawi FBgn0122115 I
GI11623 Drosophila mojavensis FBgn0134383 I
GL22763 Drosophila persimilis FBgn0160354 I
GK20555 Drosophila willistoni FBgn0222552 I
GE20234 Drosophila yakuba FBgn0237554 I
GB52677 Apis mellifera GB52677 I
HelroG74778 Helobdella robusta HelroG74778 I
HelroG77530 Helobdella robusta HelroG77530 I
ISCW002976 Ixodes scapularis ISCW002976 I
KGM_07701 Danaus plexippus KGM_07701 I
KGM_18551 Danaus plexippus KGM_18551 I
L798_01624 Zootermopsis nevadensis L798_01624 I
LOAG_18033 Loa loa LOAG_18033 I
LotgiG106315 Lottia gigantea LotgiG106315 I
LotgiG178394 Lottia gigantea LotgiG178394 I
ML025018a Mnemiopsis leidyi ML025018a I
MYCFIDRAFT_86251 Pseudocercospora fijiensis MYCFIDRAFT_86251 I
Mycgr3G42864 Zymoseptoria tritici Mycgr3G42864 I
NEMVEDRAFT_v1g118122 Nematostella vectensis NEMVEDRAFT_v1g118122 I
NV14169 Nasonia vitripennis NV14169 I
PHUM328000 Pediculus humanus PHUM328000 I
PODANS_7_5690 Podospora anserina PODANS_7_5690 I
RPRC013473 Rhodnius prolixus RPRC013473 I
SEPMUDRAFT_146565 Sphaerulina musiva SEPMUDRAFT_146565 I
SINV25829 Solenopsis invicta SINV25829 I
SMAR014746 Strigamia maritima SMAR014746 I
Smp_135710 Schistosoma mansoni Smp_135710 I
Smp_145650 Schistosoma mansoni Smp_145650 I
TC005482 Tribolium castaneum TC005482 I
tetur27g00040 Tetranychus urticae tetur27g00040 I
TriadG21017 Trichoplax adhaerens TriadG21017 I
YQE_12737 Dendroctonus ponderosae YQE_12737 I
Aan_R009860 Calypte anna Aan_R009860 I
Aan_R012884 Calypte anna Aan_R012884 I
Afo_R006459 Aptenodytes forsteri Afo_R006459 I
Afo_R012328 Aptenodytes forsteri Afo_R012328 I
Alligator_sinensis_CCG012352.1 Alligator sinensis Alligator_sinensis_CCG012352.1 I
Alligator_sinensis_CCG017716.1 Alligator sinensis Alligator_sinensis_CCG017716.1 I
Brh_R000384 Buceros rhinoceros Brh_R000384 I
Brh_R012048 Buceros rhinoceros Brh_R012048 I
Cflo_08790--XP_623740.2_APIME Camponotus floridanus Cflo_08790--XP_623740.2_APIME I
Cmyd_10008356 Chelonia mydas Cmyd_10008356 I
Cmyd_10016625 Chelonia mydas Cmyd_10016625 I
ENSBTAP00000004805-D1 Bos grunniens ENSBTAP00000004805-D1 I
ENSBTAP00000050534-D2 Bos grunniens ENSBTAP00000050534-D2 I
ENSMMUP00000014713 Macaca fascicularis ENSMMUP00000014713 I
ENSP00000304286 Macaca fascicularis ENSP00000304286 I
ENSP00000335677 Macaca fascicularis ENSP00000335677 I
Gfo_R007042 Geospiza fortis Gfo_R007042 I
Gfo_R007363 Geospiza fortis Gfo_R007363 I
Gfo_R011197 Geospiza fortis Gfo_R011197 I
Hsal_11379--XP_623740.2_APIME Harpegnathos saltator Hsal_11379--XP_623740.2_APIME I
Myotis_brandtii_FOXI1_10007902 Myotis brandtii Myotis_brandtii_FOXI1_10007902 I
Myotis_brandtii_FOXK2_10007417 Myotis brandtii Myotis_brandtii_FOXK2_10007417 I
Ogr15673 Ophisaurus gracilis Ogr15673 I
Ogr15750 Ophisaurus gracilis Ogr15750 I
Pvit_01140 Pogona vitticeps Pvit_01140 I
Pvit_01740 Pogona vitticeps Pvit_01740 I
Pvit_09672 Pogona vitticeps Pvit_09672 I
Pvit_14157 Pogona vitticeps Pvit_14157 I
Tal_R008515 Tyto alba Tal_R008515 I
Tal_R009325 Tyto alba Tal_R009325 I
e_gw1.5.1601.1 Mycosphaerella graminicola e_gw1.5.1601.1 I
estExt_fgenesh1_pg.C_11401 Mycosphaerella fijiensis estExt_fgenesh1_pg.C_11401 I
estExt_fgenesh2_pg.C_1390059 Branchiostoma floridae estExt_fgenesh2_pg.C_1390059 I
estExt_fgenesh2_pg.C_2230025 Branchiostoma floridae estExt_fgenesh2_pg.C_2230025 I
gw1.3.684.1 Monosiga brevicollis gw1.3.684.1 I
gw1.9.461.1 Mucor circinelloides gw1.9.461.1 I
Ocbimv22014751m.g Octopus bimaculoides Ocbimv22014751m.g I
Sakowv30045469m.g Saccoglossus kowalevskii Sakowv30045469m.g I
CLEC005770 Cimex lectularius CLEC005770 I
LCUP004460 Lucilia cuprina LCUP004460 I
LDEC009844 Leptinotarsa decemlineata LDEC009844 I
SMU15006235 Schmidtea mediterranea SMU15006235 I
SNAPOd2T00016515001 Oikopleura dioica SNAPOd2T00016515001 I
SNAPOd2T00017674001 Oikopleura dioica SNAPOd2T00017674001 I
foxk2 Xenopus tropicalis XB-GENE-483520 I
foxi1 Xenopus tropicalis XB-GENE-494125 I
foxi1.L Xenopus laevis XB-GENE-494129 I
foxk2.L Xenopus laevis XB-GENE-864986 I
XP_002157478.1 Hydra magnipapillata XP_002157478.1 I
AALB006374 Anopheles albimanus AALB006374 I
AARA007704 Anopheles arabiensis AARA007704 I
AATE005236 Anopheles atroparvus AATE005236 I
AATE010245 Anopheles atroparvus AATE010245 I
ACHR003325 Anopheles christyi ACHR003325 I
ACHR009416 Anopheles christyi ACHR009416 I
ACOM025160 Anopheles coluzzii ACOM025160 I
ACUA002943 Anopheles culicifacies ACUA002943 I
ADIR007813 Anopheles dirus ADIR007813 I
ADIR009268 Anopheles dirus ADIR009268 I
AFAF011451 Anopheles farauti AFAF011451 I
AFUN010432 Anopheles funestus AFUN010432 I
AMEC018059 Anopheles melas AMEC018059 I
AMEM001535 Anopheles merus AMEM001535 I
AMEM017716 Anopheles merus AMEM017716 I
AMIN005769 Anopheles minimus AMIN005769 I
AQUA005742 Anopheles quadriannulatus AQUA005742 I
AQUA011073 Anopheles quadriannulatus AQUA011073 I
ASIS017558 Anopheles sinensis ASIS017558 I
ASIS018090 Anopheles sinensis ASIS018090 I
ASTEI07780 Anopheles stephensi ASTEI07780 I
BGLB010552 Biomphalaria glabrata BGLB010552 I
MDOA009504 Musca domestica MDOA009504 I
A_00735 Schistosoma haematobium A_00735 I
A_02445 Schistosoma haematobium A_02445 I
ALUE_0001375901 Ascaris lumbricoides ALUE_0001375901 I
ASU_13563 Ascaris suum ASU_13563 I
csin104981 Clonorchis sinensis csin104981 I
D915_05410 Fasciola hepatica D915_05410 I
D915_12475 Fasciola hepatica D915_12475 I
D917_03929 Trichinella nativa D917_03929 I
D918_06898 Trichuris suis D918_06898 I
ECANG7_07925 Echinococcus canadensis ECANG7_07925 I
ECPE_0000905801 Echinostoma caproni ECPE_0000905801 I
HmN_000131600 Hymenolepis microstoma HmN_000131600 I
HNAJ_0000565501 Hymenolepis nana HNAJ_0000565501 I
L596_g2916 Steinernema carpocapsae L596_g2916 I
L892_g3155 Steinernema scapterisci L892_g3155 I
L893_g1479 Steinernema glaseri L893_g1479 I
L898_g7434 Steinernema monticolum L898_g7434 I
MCOS_0000744701 Mesocestoides corti MCOS_0000744701 I
nDi.2.2.2.g09096 Dirofilaria immitis nDi.2.2.2.g09096 I
nDi.2.2.2.g09529 Dirofilaria immitis nDi.2.2.2.g09529 I
nLs.2.1.2.g01892 Litomosoides sigmodontis nLs.2.1.2.g01892 I
nOo.2.0.1.g03356 Onchocerca ochengi nOo.2.0.1.g03356 I
OFLC_0001379001 Onchocerca flexuosa OFLC_0001379001 I
SCUD_0001296501 Schistosoma curassoni SCUD_0001296501 I
SCUD_0002144401 Schistosoma curassoni SCUD_0002144401 I
SMRZ_0002168001 Schistosoma margrebowiei SMRZ_0002168001 I
SMTD_0000908801 Schistosoma mattheei SMTD_0000908801 I
SROB_0001634001 Schistosoma rodhaini SROB_0001634001 I
T265_14440 Opisthorchis viverrini T265_14440 I
TASK_0000593301 Taenia asiatica TASK_0000593301 I
TMUE_s0028005600 Trichuris muris TMUE_s0028005600 I
TsM_000087000 Taenia solium TsM_000087000 I
TTRE_0000290501 Trichuris trichiura TTRE_0000290501 I