ztf-11 (Caenorhabditis elegans)
C2HC ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF01530 (zf-C2HC) IPR002515 WBGene00009939 T159400_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable zinc ion binding activity. Involved in nematode larval development; neuron differentiation; and positive regulation of cell differentiation. Located in nucleus. Is expressed in g1 and head neurons. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability 39. Orthologous to human ST18 (ST18 C2H2C-type zinc finger transcription factor); MYT1 (myelin transcription factor 1); and MYT1L (myelin transcription factor 1 like). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
ztf-11
M00650_2.00		 Caenorhabditis elegans
VAAGTTTN
NAAACTTB		 PBM
Narasimhan et al.(2015)
pTH9925		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.700 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00650_2.00 C2HC ZF 53 80
M00650_2.00 C2HC ZF 99 127

DNA Binding Domains

Protein ID Domain From To Sequence
F52F12.6a C2HC ZF 264 291
F52F12.6a C2HC ZF 310 338
F52F12.6b C2HC ZF 167 194
F52F12.6b C2HC ZF 213 241

Links

Other C2HC ZF family TFs
Other Caenorhabditis elegans TFs

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63 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action