CIS-BP Database: Catalog of Inferred Sequence Binding Preferences

TF Information

MDP0000124881 *(Malus domestica)* E2F
Pfam ID	Interpro ID	Gene ID	CIS-BP ID	Sequence source
PF02319 (E2F_TDP)	IPR003316	MDP0000124881	T173968_2.00	JGI:Phytozome (2018-Apr-12)
Directly determined binding motifs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
No direct experiments
Motifs from related TFs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
E2FC M06870_2.00	Arabidopsis thaliana	AWDDDGGCGCCAAAR	YTTTGGCGCCHHHWT	Dap-seq OMalley et al.(2016) E2FC_col_a	0.754	0.754
ENSOANG00000014967 M01962_2.00	Ornithorhynchus anatinus	NDSGCGCSHN	NDSGCGCSHN	PBM Weirauch et al.(2014) pTH9382	0.719	0.719
E2F2 M01963_2.00	Tupaia belangeri	WDVGCGCBHW	WDVGCGCBHW	PBM Weirauch et al.(2014) pTH9291	0.719	0.719
E2FA M06871_2.00	Arabidopsis thaliana	NDDDGGCGCCAWWW	WWWTGGCGCCHHHN	Dap-seq OMalley et al.(2016) E2FA_col_a	0.719	0.719
E2FA M06872_2.00	Arabidopsis thaliana	DDWDGGCGCCAWAD	HTWTGGCGCCHWHH	Dap-seq OMalley et al.(2016) E2FA_colamp_a	0.719	0.719
E2FA M08106_2.00	Arabidopsis thaliana	NVGCGCCAHN	NDTGGCGCBN	ChIP-seq Mathelier et al.(2014) MA1414.1	0.719	0.719
ENSACAG00000013716 M01960_2.00	Anolis carolinensis	HNVGCGCBND	HNVGCGCBND	PBM Weirauch et al.(2014) pTH9221	0.702	0.702
E2f2 M00154_2.00	Mus musculus	NDNNGCGSBN	NVSCGCNNHN	PBM Badis et al.(2009) E2F2_1022	0.702	0.702
E2F3 M01964_2.00	Taeniopygia guttata	NNSGCGCGMN	NKCGCGCSNN	PBM Weirauch et al.(2014) pTH9288	0.702	0.702
E2f2 M09039_2.00	Mus musculus	GGCGCGMAWC	GWTKCGCGCC	Misc Kulakovskiy et al.(2013) E2F2_MOUSE.H11MO.0.B	0.702	0.702
E2F2 M01961_2.00	Homo sapiens	DNSGCGCSNH	DNSGCGCSNH	PBM Weirauch et al.(2014) pTH9195	0.684	0.684
E2f3 M00153_2.00	Mus musculus	NNNNGCGSNN	NNSCGCNNNN	PBM Badis et al.(2009) E2F3_3752	0.684	0.684
e_gw1.38.2.1 M01968_2.00	Physcomitrella patens	NSGCGCBHHN	NDDVGCGCSN	PBM Weirauch et al.(2014) pTH5707	0.684	0.684
estExt_gwp_gw1.C_220046 M01225_2.00	Physcomitrella patens	VGCGCBHHNN	NNDDVGCGCB	PBM Lambert et al.(2019) pTH9809	0.684	0.684
E2F2 M02949_2.00	Homo sapiens	AAAAATGGCGCCAAAAWD	HWTTTTGGCGCCATTTTT	SELEX Jolma et al.(2013) E2F2_1	0.684	0.684
E2F2 M02950_2.00	Homo sapiens	VDTTTTGGCGCCAAAAHN	NDTTTTGGCGCCAAAAHB	SELEX Jolma et al.(2013) E2F2_2	0.684	0.684
E2F2 M02951_2.00	Homo sapiens	AAAWWGGCGCCAWTTT	AAAWTGGCGCCWWTTT	SELEX Jolma et al.(2013) E2F2_3	0.684	0.684
E2F3 M02956_2.00	Homo sapiens	RAAAAKGGCGCCAAAANN	NNTTTTGGCGCCMTTTTY	SELEX Jolma et al.(2013) E2F3_1	0.684	0.684
E2F3 M02957_2.00	Homo sapiens	DAAAADGGCGCCMWWTTY	RAAWWKGGCGCCHTTTTH	SELEX Jolma et al.(2013) E2F3_2	0.684	0.684
E2F3 M02958_2.00	Homo sapiens	NDTTTTGGCGCCAAAABH	DVTTTTGGCGCCAAAAHN	SELEX Jolma et al.(2013) E2F3_3	0.684	0.684
E2F3 M04701_2.00	Homo sapiens	DWTTTGGCGCCAAAWH	DWTTTGGCGCCAAAWH	SELEX Yin et al.(2017) E2F3_eDBD_HT-SELEX	0.684	0.684
E2F2 M04696_2.00	Homo sapiens	GCGCGCGCSYW	WRSGCGCGCGC	SELEX Yin et al.(2017) E2F2_eDBD_HT-SELEX_1	0.684	0.684
E2F2 M04697_2.00	Homo sapiens	NDWWDGGCGCCWWHWN	NWDWWGGCGCCHWWHN	SELEX Yin et al.(2017) E2F2_eDBD_HT-SELEX_2	0.684	0.684
E2F2 M09029_2.00	Homo sapiens	GGCGCGMAWC	GWTKCGCGCC	Misc Kulakovskiy et al.(2013) E2F2_HUMAN.H11MO.0.B	0.684	0.684
E2F3 M09031_2.00	Homo sapiens	NDGGCGGGAAR	YTTCCCGCCHN	Misc Kulakovskiy et al.(2013) E2F3_HUMAN.H11MO.0.A	0.684	0.684
E2f3 M09038_2.00	Mus musculus	DSGCGGGARV	BYTCCCGCSH	Misc Kulakovskiy et al.(2013) E2F3_MOUSE.H11MO.0.A	0.684	0.684
E2F3 M10454_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$E2F1_Q6_01	0.684	0.684
E2F3 M10455_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$E2F3_Q6	0.684	0.684
E2F3 M04702_2.00	Homo sapiens	DTTTTGGCGCCAAAAH	DTTTTGGCGCCAAAAH	SELEX Yin et al.(2017) E2F3_eDBD_Methyl-HT-SELEX	0.684	0.684
E2F2 M04698_2.00	Homo sapiens	SGBGSGCGCGS	SCGCGCSCVCS	SELEX Yin et al.(2017) E2F2_eDBD_Methyl-HT-SELEX_1	0.684	0.684
E2F2 M04699_2.00	Homo sapiens	DWWWDGGCGCCAAAWH	DWTTTGGCGCCHWWWH	SELEX Yin et al.(2017) E2F2_eDBD_Methyl-HT-SELEX_2	0.684	0.684
E2F4 M02961_2.00	Homo sapiens	AATGGCGCCAAA	TTTGGCGCCATT	SELEX Jolma et al.(2013) E2F4_1	0.649	0.649
E2F4 M02962_2.00	Homo sapiens	TTTGGCGCCAAA	TTTGGCGCCAAA	SELEX Jolma et al.(2013) E2F4_2	0.649	0.649
E2F4 M04707_2.00	Homo sapiens	NWWKGGCGCCAAAW	WTTTGGCGCCMWWN	SELEX Yin et al.(2017) E2F4_eDBD_HT-SELEX	0.649	0.649
E2F4 M08109_2.00	Homo sapiens	NSGCGGGARVN	NBYTCCCGCSN	ChIP-seq Mathelier et al.(2014) MA0470.1	0.649	0.649
E2F4 M07942_2.00	Homo sapiens	SGCGSGARDNNBNVN	NBNVNNHYTCSCGCS	ChIP-seq Gerstein et al.(2012) HeLa-S3_E2F4_UCD	0.649	0.649
E2F4 M07943_2.00	Homo sapiens	SGCGGGARDNNBVVN	NBBVNNHYTCCCGCS	ChIP-seq Gerstein et al.(2012) K562b_E2F4_UCD	0.649	0.649
E2F4 M09036_2.00	Homo sapiens	VDRGGCGGGRVND	HNBYCCCGCCYHB	Misc Kulakovskiy et al.(2013) E2F4_HUMAN.H11MO.0.A	0.649	0.649
E2f4 M09037_2.00	Mus musculus	NRDDGGCGGGRMNN	NNKYCCCGCCHHYN	Misc Kulakovskiy et al.(2013) E2F4_MOUSE.H11MO.0.A	0.649	0.649
E2F4 M09524_2.00	Homo sapiens	VGCGSGAADH	DHTTCSCGCB	Misc Heinz et al.(2010) K562-E2F4_GSE31477	0.649	0.649
E2F4 M10457_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$E2F4_05	0.649	0.649
E2F4 M10458_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$E2F4_Q3	0.649	0.649
E2F4 M10459_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$E2F4_Q6	0.649	0.649
E2f5 M09042_2.00	Mus musculus	NGCGCSAAAN	NTTTSGCGCN	Misc Kulakovskiy et al.(2013) E2F5_MOUSE.H11MO.0.B	0.632	0.632
efl-1 M08110_2.00	Caenorhabditis elegans	HNHNSGCGSSAAWWN	NWWTTSSCGCSNDND	ChIP-seq Mathelier et al.(2014) MA0541.1	0.614	0.614
E2f M08196_2.00	Drosophila melanogaster	AAWWBSSCGSCAA	TTGSCGSSVWWTT	ChIP-seq Contrino et al.(2012) Mf10	0.614	0.614
efl-1 M08197_2.00	Caenorhabditis elegans	BGCGSSAAWW	WWTTSSCGCV	ChIP-seq Contrino et al.(2012) Mw140	0.614	0.614
efl-1 M09526_2.00	Caenorhabditis elegans	WGCAARYGCGCTCYA	TRGAGCGCRYTTGCW	Misc Heinz et al.(2010) cElegans-L1-EFL1_modEncode	0.614	0.614
GSPATT00020286001 M01965_2.00	Paramecium tetraurelia	NNSGCGSBN	NVSCGCSNN	PBM Weirauch et al.(2014) pTH5647	0.596	0.596
E2F1 M02952_2.00	Homo sapiens	WWDGGCGCCAAW	WTTGGCGCCHWW	SELEX Jolma et al.(2013) E2F1_1	0.579	0.579
E2F1 M02953_2.00	Homo sapiens	WWKGGCGCCWWW	WWWGGCGCCMWW	SELEX Jolma et al.(2013) E2F1_2	0.579	0.579
E2F1 M02954_2.00	Homo sapiens	WWWKGGCGCCMWWW	WWWKGGCGCCMWWW	SELEX Jolma et al.(2013) E2F1_3	0.579	0.579
E2F1 M02955_2.00	Homo sapiens	AAWKGGCGCCAWTW	WAWTGGCGCCMWTT	SELEX Jolma et al.(2013) E2F1_4	0.579	0.579
E2F1 M04700_2.00	Homo sapiens	NWWWDGGCGCCAAAWH	DWTTTGGCGCCHWWWN	SELEX Yin et al.(2017) E2F1_FL_HT-SELEX	0.579	0.579
E2F1 M07938_2.00	Homo sapiens	VRRVNRVGCGSGMDS	SHKCSCGCBYNBYYB	ChIP-seq Gerstein et al.(2012) HeLa-S3_E2F1_UCD	0.579	0.579
E2F1 M09030_2.00	Homo sapiens	NVNDGGCGGGARVN	NBYTCCCGCCHNBN	Misc Kulakovskiy et al.(2013) E2F1_HUMAN.H11MO.0.A	0.579	0.579
E2f1 M09041_2.00	Mus musculus	NDDGGCGGGRVN	NBYCCCGCCHHN	Misc Kulakovskiy et al.(2013) E2F1_MOUSE.H11MO.0.A	0.579	0.579
E2F1 M09521_2.00	Homo sapiens	NNGGCGGGAA	TTCCCGCCNN	Misc Heinz et al.(2010) Hela-E2F1_GSE22478	0.579	0.579
E2F1 M10444_2.00	Homo sapiens	THVGCGCGAAAAHKR	YMDTTTTCGCGCBDA	Transfac Matys et al.(2006) V$E2F_01	0.579	0.579
E2F1 M10445_2.00	Homo sapiens	BHKSGCGCSAAA	TTTSGCGCSMDV	Transfac Matys et al.(2006) V$E2F_03	0.579	0.579
E2F1 M10446_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$E2F1_01	0.579	0.579
E2F1 M10447_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$E2F1_02	0.579	0.579
E2F1 M10448_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$E2F1_Q3_01	0.579	0.579
E2F1 M10449_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$E2F1_Q3	0.579	0.579
E2F1 M10450_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$E2F1_Q4_01	0.579	0.579
E2F1 M10451_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$E2F1_Q4_02	0.579	0.579
E2F1 M10452_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$E2F1_Q4	0.579	0.579
E2F1 M10453_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$E2F1_Q6	0.579	0.579
E2F M01959_2.00	Dictyostelium discoideum	NNGSGCGCSHN	NDSGCGCSCNN	PBM Weirauch et al.(2014) pTH5403	0.561	0.561
E2F6 M08107_2.00	Homo sapiens	DGGMGGGARVN	NBYTCCCKCCH	ChIP-seq Mathelier et al.(2014) MA0471.1	0.561	0.561
E2F6 M07939_2.00	Homo sapiens	NDSGCGGGARV	BYTCCCGCSHN	ChIP-seq Gerstein et al.(2012) HeLa-S3_E2F6_UCD	0.561	0.561
E2F6 M07940_2.00	Homo sapiens	NDVGCGGGARV	BYTCCCGCBHN	ChIP-seq Gerstein et al.(2012) K562b_E2F6_UCD	0.561	0.561
E2F6 M07941_2.00	Homo sapiens	NDSGCGGGARV	BYTCCCGCSHN	ChIP-seq Gerstein et al.(2012) K562_E2F6_HudsonAlpha	0.561	0.561
E2F6 M09034_2.00	Homo sapiens	NRGGMGGGARRNN	NNYYTCCCKCCYN	Misc Kulakovskiy et al.(2013) E2F6_HUMAN.H11MO.0.A	0.561	0.561
E2f6 M09043_2.00	Mus musculus	NDGGCGGGARVV	BBYTCCCGCCHN	Misc Kulakovskiy et al.(2013) E2F6_MOUSE.H11MO.0.A	0.561	0.561
E2F6 M09523_2.00	Homo sapiens	VGCGGGARNN	NNYTCCCGCB	Misc Heinz et al.(2010) Hela-E2F6_GSE31477	0.561	0.561
E2F6 M10456_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$E2F6_01	0.561	0.561
estExt_gwp_GeneWisePlus.C_Chr_02.00010270 M01969_2.00	Ostreococcus tauri	HRVGCGCCNN	NNGGCGCBYD	PBM Weirauch et al.(2014) pTH5701	0.544	0.544
For this family, TFs with SR scores > 0.429* will likely have a similar motif*

DNA Binding Domains

Protein ID	Domain	From	To	Sequence
MDP0000124881	E2F	82	138	FDNSLGLLTKKFIKLIYEAKDRTLDLNRTAEVLEVQKRRIYDITNVLEGINLDEVES

Links
Other E2F family TFs
Other *Malus domestica* TFs

969 Related TFs

Name	Species	Gene ID	Motif Evidence	SR Score	Action
DEHA2B06600g	Debaryomyces hansenii	DEHA2B06600g	I	0.000
estExt_fgenesh1_pm.C_chr_3.10124	Pichia stipitis	estExt_fgenesh1_pm.C_chr_3.10124	I	0.000
TRIREDRAFT_53484	Trichoderma reesei	TRIREDRAFT_53484	I	0.000
TRIATDRAFT_133472	Trichoderma atroviride	TRIATDRAFT_133472	I	0.000
SPAPADRAFT_133262	Spathaspora passalidarum	SPAPADRAFT_133262	I	0.000
SCLCIDRAFT_1209974	Scleroderma citrinum	SCLCIDRAFT_1209974	I	0.000
PICST_65402	Scheffersomyces stipitis	PICST_65402	I	0.000
OCS_04566	Ophiocordyceps sinensis	OCS_04566	I	0.000
LELG_01582	Lodderomyces elongisporus	LELG_01582	I	0.000
JL09_g2919	Pichia kudriavzevii	JL09_g2919	I	0.000
GNLVRS01_PISO0N11915g	Millerozyma farinosa	GNLVRS01_PISO0N11915g	I	0.000
GNLVRS01_PISO0M11606g	Millerozyma farinosa	GNLVRS01_PISO0M11606g	I	0.000
G210_2921	Candida maltosa	G210_2921	I	0.000
CPAG_00894	Candida parapsilosis	CPAG_00894	I	0.000
CTRG_04585	Candida tropicalis	CTRG_04585	I	0.000
CPUR_02732	Claviceps purpurea	CPUR_02732	I	0.000
CORT_0B10160	Candida orthopsilosis	CORT_0B10160	I	0.000
Cob_02496	Colletotrichum orbiculare	Cob_02496	I	0.000
CD36_01630	Candida dubliniensis	CD36_01630	I	0.000
CaO19.4545	Candida albicans	CaO19.4545	I	0.000
CaO19.12020	Candida albicans	CaO19.12020	I	0.000
CANTEDRAFT_102423	Candida tenuis	CANTEDRAFT_102423	I	0.000
BN7_4296	Wickerhamomyces ciferrii	BN7_4296	I	0.000
ACRE_080650	Acremonium chrysogenum	ACRE_080650	I	0.000
CLUG_00097	Clavispora lusitaniae	CLUG_00097	N	0.000
PGUG_00771	Meyerozyma guilliermondii	PGUG_00771	N	0.000
PGUG_00771	Candida guilliermondii	PGUG_00771	N	0.000

MDP0000124881 (Malus domestica) E2F

TF Information

Directly determined binding motifs

Motifs from related TFs

DNA Binding Domains

Links

969 Related TFs

MDP0000124881 **(Malus domestica)
E2F**