CIS-BP Database: Catalog of Inferred Sequence Binding Preferences

TF Information

Spdef *(Mus musculus)* Ets
Pfam ID	Interpro ID	Gene ID	CIS-BP ID	Sequence source	Animal TF db
PF00178 (Ets)	IPR000418	ENSMUSG00000024215	T176540_2.00	Ensembl (2018-Dec-8)	Link out
Directly determined binding motifs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
Spdef M00159_2.00	Mus musculus	NNVMGGAHNN	NNDTCCKBNN	PBM Badis et al.(2009) Spdef_0905	(Direct)	(Direct)
Spdef M01488_2.00	Mus musculus	NDNVMGGAHN	NDTCCKBNHN	PBM Wei et al.(2010) Spdef	(Direct)	(Direct)
Motifs from related TFs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
SPDEF M02973_2.00	Homo sapiens	AMCCGGATRTD	HAYATCCGGKT	SELEX Jolma et al.(2013) SPDEF_1	0.996	0.988
SPDEF M02974_2.00	Homo sapiens	ATRATCCGGGAMMHY	RDKKTCCCGGATYAT	SELEX Jolma et al.(2013) SPDEF_2	0.996	0.988
SPDEF M02975_2.00	Homo sapiens	RCAGDAAGAAGTAWWM	KWWTACTTCTTHCTGY	SELEX Jolma et al.(2013) SPDEF_3	0.996	0.988
SPDEF M02976_2.00	Homo sapiens	AMCCGGATRTD	HAYATCCGGKT	SELEX Jolma et al.(2013) SPDEF_4	0.996	0.988
SPDEF M02977_2.00	Homo sapiens	WTRATCCGGGACCMC	GKGGTCCCGGATYAW	SELEX Jolma et al.(2013) SPDEF_5	0.996	0.988
SPDEF M02978_2.00	Homo sapiens	RCAGDAAGAMGTAWHM	KDWTACKTCTTHCTGY	SELEX Jolma et al.(2013) SPDEF_6	0.996	0.988
SPDEF M04748_2.00	Homo sapiens	NWVCCGGATRYN	NRYATCCGGBWN	SELEX Yin et al.(2017) SPDEF_eDBD_HT-SELEX	0.996	0.988
SPDEF M04750_2.00	Homo sapiens	NWVCCGGATRYN	NRYATCCGGBWN	SELEX Yin et al.(2017) SPDEF_FL_HT-SELEX	0.996	0.988
SPDEF M09530_2.00	Homo sapiens	WVCMGGAWVY	RBWTCCKGBW	Misc Heinz et al.(2010) VCaP-SPDEF_SRA014231	0.996	0.988
SPDEF M04749_2.00	Homo sapiens	NAVCMGGATRYD	HRYATCCKGBTN	SELEX Yin et al.(2017) SPDEF_eDBD_Methyl-HT-SELEX	0.996	0.988
SPDEF M04751_2.00	Homo sapiens	NAVCMGKATRYD	HRYATMCKGBTN	SELEX Yin et al.(2017) SPDEF_FL_Methyl-HT-SELEX	0.996	0.988
Ets98B M03727_2.00	Drosophila melanogaster	TAMCGGATGCN	NGCATCCGKTA	SELEX Nitta et al.(2015) Ets98B_1	0.984	0.765
Ets98B M03728_2.00	Drosophila melanogaster	TKGCGGATGCN	NGCATCCGCMA	SELEX Nitta et al.(2015) Ets98B_2	0.984	0.765
Ets98B M03729_2.00	Drosophila melanogaster	ATGATCCGGGACN	NGTCCCGGATCAT	SELEX Nitta et al.(2015) Ets98B_3	0.984	0.765
Ets98B M03730_2.00	Drosophila melanogaster	GSATMCGKTA	TAMCGKATSC	SELEX Nitta et al.(2015) Ets98B_4	0.984	0.765
Ets98B M03731_2.00	Drosophila melanogaster	ATGATCCGGGASN	NSTCCCGGATCAT	SELEX Nitta et al.(2015) Ets98B_5	0.984	0.765
Ets98B M06191_2.00	Drosophila melanogaster	ASCCGGAWC	GWTCCGGST	B1H Zhu et al.(2011) Ets98B_SANGER_10_FBgn0005659	0.984	0.765
Elf2 M01494_2.00	Mus musculus	NNVMGGAAVH	DBTTCCKBNN	PBM Wei et al.(2010) Elf2	0.803	0.506
ELF2 M04722_2.00	Homo sapiens	NWHSCGGAAGTN	NACTTCCGSDWN	SELEX Yin et al.(2017) ELF2_eDBD_HT-SELEX_1	0.803	0.506
ELF2 M04723_2.00	Homo sapiens	DRBSCGGAAGTD	HACTTCCGSVYH	SELEX Yin et al.(2017) ELF2_eDBD_HT-SELEX_2	0.803	0.506
ELF2 M04726_2.00	Homo sapiens	NAMCCGGAAGTV	BACTTCCGGKTN	SELEX Yin et al.(2017) ELF2_FL_HT-SELEX_1	0.803	0.506
ELF2 M04727_2.00	Homo sapiens	DAYSCGGAAGTR	YACTTCCGSRTH	SELEX Yin et al.(2017) ELF2_FL_HT-SELEX_2	0.803	0.506
ELF2 M09049_2.00	Homo sapiens	NDVSCGGAAGYVV	BBRCTTCCGSBHN	Misc Kulakovskiy et al.(2013) ELF2_HUMAN.H11MO.0.C	0.803	0.506
Elf2 M09080_2.00	Mus musculus	YDNCAGGAAGBRRVK	MBYYVCTTCCTGNHR	Misc Kulakovskiy et al.(2013) ELF2_MOUSE.H11MO.0.C	0.803	0.506
ELF2 M10480_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$NERF_Q2	0.803	0.506
ELF2 M04724_2.00	Homo sapiens	NWHCMGGAAGTR	YACTTCCKGDWN	SELEX Yin et al.(2017) ELF2_eDBD_Methyl-HT-SELEX_1	0.803	0.506
ELF2 M04725_2.00	Homo sapiens	DANVCGGAAGTD	HACTTCCGBNTH	SELEX Yin et al.(2017) ELF2_eDBD_Methyl-HT-SELEX_2	0.803	0.506
ELF2 M04728_2.00	Homo sapiens	AAMCMGGAAGTR	YACTTCCKGKTT	SELEX Yin et al.(2017) ELF2_FL_Methyl-HT-SELEX_1	0.803	0.506
ELF2 M04729_2.00	Homo sapiens	RAYSMGGAAGTR	YACTTCCKSRTT	SELEX Yin et al.(2017) ELF2_FL_Methyl-HT-SELEX_2	0.803	0.506
Eip74EF M03723_2.00	Drosophila melanogaster	WACCCGGAAGTR	YACTTCCGGGTW	SELEX Nitta et al.(2015) Eip74EF_1	0.761	0.556
Eip74EF M03724_2.00	Drosophila melanogaster	WABSCGGAAGTR	YACTTCCGSVTW	SELEX Nitta et al.(2015) Eip74EF_2	0.761	0.556
Eip74EF M06186_2.00	Drosophila melanogaster	WHMAGGAAKT	AMTTCCTKDW	B1H Zhu et al.(2011) Eip74EF_FlyReg_FBgn0000567	0.761	0.556
Eip74EF M06187_2.00	Drosophila melanogaster	ACCCGGAAGT	ACTTCCGGGT	B1H Zhu et al.(2011) Eip74EF_SANGER_5_FBgn0000567	0.761	0.556
Eip74EF M02679_2.00	Drosophila melanogaster	CMGGAAR	YTTCCKG	SELEX Mathelier et al.(2014) MA0026.1	0.761	0.556
Eip74EF M09667_2.00	Drosophila melanogaster	VWHMMGGAART	AYTTCCKKDWB	Misc Kulakovskiy et al.(2009) Eip74EF	0.761	0.556
Eip74EF M10521_2.00	Drosophila melanogaster	NNAAYCMGGAARTNNDV	BHNNAYTTCCKGRWTNN	Transfac Matys et al.(2006) I$E74A_01	0.761	0.556
ELF1 M02971_2.00	Homo sapiens	DACCCGGAAGTV	BACTTCCGGGTH	SELEX Jolma et al.(2013) ELF1_1	0.760	0.506
ELF1 M02972_2.00	Homo sapiens	WACCCGGAAGTR	YACTTCCGGGTW	SELEX Jolma et al.(2013) ELF1_2	0.760	0.506
ELF1 M04740_2.00	Homo sapiens	NWHSCGGAAGYN	NRCTTCCGSDWN	SELEX Yin et al.(2017) ELF1_eDBD_HT-SELEX_1	0.760	0.506
ELF1 M04741_2.00	Homo sapiens	NDBVCGGAAGTN	NACTTCCGBVHN	SELEX Yin et al.(2017) ELF1_eDBD_HT-SELEX_2	0.760	0.506
ELF1 M04744_2.00	Homo sapiens	NWHSCGGAAGYN	NRCTTCCGSDWN	SELEX Yin et al.(2017) ELF1_FL_HT-SELEX_1	0.760	0.506
ELF1 M04745_2.00	Homo sapiens	DWBVCGGAAGTD	HACTTCCGBVWH	SELEX Yin et al.(2017) ELF1_FL_HT-SELEX_2	0.760	0.506
ELF1 M07947_2.00	Homo sapiens	VVVDSSCGGAAGYSS	SSRCTTCCGSSHBBB	ChIP-seq Gerstein et al.(2012) GM12878_ELF1_HudsonAlpha	0.760	0.506
ELF1 M07948_2.00	Homo sapiens	NVDVSCGGAAGYVV	BBRCTTCCGSBHBN	ChIP-seq Gerstein et al.(2012) HepG2_ELF1_HudsonAlpha	0.760	0.506
ELF1 M07949_2.00	Homo sapiens	DVSCGGAAGYG	CRCTTCCGSBH	ChIP-seq Gerstein et al.(2012) K562_ELF1_HudsonAlpha	0.760	0.506
ELF1 M08198_2.00	Homo sapiens	WCCCGGAAGY	RCTTCCGGGW	ChIP-seq Contrino et al.(2012) Mv63	0.760	0.506
ELF1 M09050_2.00	Homo sapiens	VVWNSMGGAAGYVS	SBRCTTCCKSNWBB	Misc Kulakovskiy et al.(2013) ELF1_HUMAN.H11MO.0.A	0.760	0.506
Elf1 M09079_2.00	Mus musculus	VVDVSCGGAAGYVV	BBRCTTCCGSBHBB	Misc Kulakovskiy et al.(2013) ELF1_MOUSE.H11MO.0.A	0.760	0.506
ELF1 M09529_2.00	Homo sapiens	NVCCGGAAGY	RCTTCCGGBN	Misc Heinz et al.(2010) Jurkat-ELF1_SRA014231	0.760	0.506
ELF1 M10483_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$ELF1_03	0.760	0.506
ELF1 M10484_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$ELF1_07	0.760	0.506
ELF1 M10485_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$ELF1_Q4	0.760	0.506
ELF1 M10486_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$ELF1_Q5	0.760	0.506
ELF1 M10487_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$ELF1_Q6	0.760	0.506
ELF1 M04742_2.00	Homo sapiens	NWNSMGGAAGTR	YACTTCCKSNWN	SELEX Yin et al.(2017) ELF1_eDBD_Methyl-HT-SELEX_1	0.760	0.506
ELF1 M04743_2.00	Homo sapiens	DDNVMGGAAGTR	YACTTCCKBNHH	SELEX Yin et al.(2017) ELF1_eDBD_Methyl-HT-SELEX_2	0.760	0.506
ELF1 M04746_2.00	Homo sapiens	NWHCMGGAAGTN	NACTTCCKGDWN	SELEX Yin et al.(2017) ELF1_FL_Methyl-HT-SELEX_1	0.760	0.506
ELF1 M04747_2.00	Homo sapiens	DABSCGGAAGTR	YACTTCCGSVTH	SELEX Yin et al.(2017) ELF1_FL_Methyl-HT-SELEX_2	0.760	0.506
Elf4 M01492_2.00	Mus musculus	NNVMGGAAVH	DBTTCCKBNN	PBM Wei et al.(2010) Elf4	0.760	0.494
ELF4 M02966_2.00	Homo sapiens	DACCCGGAAGTR	YACTTCCGGGTH	SELEX Jolma et al.(2013) ELF4_1	0.760	0.494
ELF4 M04716_2.00	Homo sapiens	NWHSCGGAAGTN	NACTTCCGSDWN	SELEX Yin et al.(2017) ELF4_eDBD_HT-SELEX_1	0.760	0.494
ELF4 M04717_2.00	Homo sapiens	NABSCGGAAGTR	YACTTCCGSVTN	SELEX Yin et al.(2017) ELF4_eDBD_HT-SELEX_2	0.760	0.494
ELF4 M04718_2.00	Homo sapiens	NAHCMGGAAGTR	YACTTCCKGDTN	SELEX Yin et al.(2017) ELF4_eDBD_Methyl-HT-SELEX_1	0.760	0.494
ELF4 M04719_2.00	Homo sapiens	NANVMGGAAGTD	HACTTCCKBNTN	SELEX Yin et al.(2017) ELF4_eDBD_Methyl-HT-SELEX_2	0.760	0.494
For this family, TFs with SR scores > 0.717* will likely have a similar motif*

Experimental Constructs

Motif ID	Domain	From	To	Sequence
M00159_2.00	Ets	18	100	HLWQFLKELLLKPHSYGRFIRWLNKEKGIFKIEDSAQVARLWGVRKNRPAMNYDKLSRSIRQYYKKGIIRKPDISQRLVYQFV
M01488_2.00	Ets	240	322	HLWQFLKELLLKPHSYGRFIRWLNKEKGIFKIEDSAQVARLWGVRKNRPAMNYDKLSRSIRQYYKKGIIRKPDISQRLVYQFV

DNA Binding Domains

Protein ID	Domain	From	To	Sequence
ENSMUSP00000025054	Ets	240	322	HLWQFLKELLLKPHSYGRFIRWLNKEKGIFKIEDSAQVARLWGVRKNRPAMNYDKLSRSIRQYYKKGIIRKPDISQRLVYQFV
ENSMUSP00000110520	Ets	240	322	HLWQFLKELLLKPHSYGRFIRWLNKEKGIFKIEDSAQVARLWGVRKNRPAMNYDKLSRSIRQYYKKGIIRKPDISQRLVYQFV
ENSMUSP00000127056	Ets	240	322	HLWQFLKELLLKPHSYGRFIRWLNKEKGIFKIEDSAQVARLWGVRKNRPAMNYDKLSRSIRQYYKKGIIRKPDISQRLVYQFV

Links
Other Ets family TFs
Other *Mus musculus* TFs

494 Related TFs

Name	Species	Gene ID	Motif Evidence	SR Score	Action
SPRG_01851	Saprolegnia parasitica	SPRG_01851	N
F443_02170	Phytophthora parasitica	F443_02170	N
fgenesh_scip_prom.28083.8513	Phytophthora lateralis	fgenesh_scip_prom.28083.8513	N
fgenesh_scip_prom.46568.2994	Phytophthora kernoviae	fgenesh_scip_prom.46568.2994	N
HpaG800546	Hyaloperonospora arabidopsidis	HpaG800546	N
HpaG806838	Hyaloperonospora arabidopsidis	HpaG806838	N
maker-pag1_scaffold_241-snap-gene-0.5	Pythium aphanidermatum	maker-pag1_scaffold_241-snap-gene-0.5	N
maker-pag1_scaffold_241-snap-gene-0.8	Pythium aphanidermatum	maker-pag1_scaffold_241-snap-gene-0.8	N
maker-par_contig_498-fgenesh-gene-0.0	Pythium arrhenomanes	maker-par_contig_498-fgenesh-gene-0.0	N
maker-pir_contig_962-fgenesh-gene-0.0	Pythium irregulare	maker-pir_contig_962-fgenesh-gene-0.0	N
maker-pve_contig_244-fgenesh-gene-0.3	Pythium vexans	maker-pve_contig_244-fgenesh-gene-0.3	N
Phyra75938	Phytophthora ramorum	Phyra75938	N
PITG_05734	Phytophthora infestans	PITG_05734	N
PYU1_G005004	Pythium ultimum	PYU1_G005004	N
snap-piw_contig_1471-abinit-gene-0.10	Pythium iwayamai	snap-piw_contig_1471-abinit-gene-0.10	N

Spdef (Mus musculus) Ets

TF Information

Directly determined binding motifs

Motifs from related TFs

Experimental Constructs

DNA Binding Domains

Links

494 Related TFs

Spdef **(Mus musculus)
Ets**