Foxh1 (Mus musculus)
Forkhead

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00250 (Forkhead) IPR001766 ENSMUSG00000033837 T186349_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables DNA-binding transcription activator activity, RNA polymerase II-specific; R-SMAD binding activity; and transcription cis-regulatory region binding activity. Involved in several processes, including aorta morphogenesis; heart morphogenesis; and regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including axial mesoderm development; determination of left/right symmetry; and embryonic heart tube anterior/posterior pattern specification. Located in nucleus. Part of activin responsive factor complex. Is expressed in several structures, including early conceptus; lung; notochord; ovary; and ureter. Used to study agnathia-otocephaly complex and visceral heterotaxy. Orthologous to human FOXH1 (forkhead box H1). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
FOXH1
M08119_2.00 		Homo sapiens
BNSAATMCACA
TGTGKATTSNV		 ChIP-seq
Mathelier et al.(2014)
MA0479.1 		0.781 0.965
FOXH1
M09092_2.00 		Homo sapiens
SAATMCACA
TGTGKATTS		 Misc
Kulakovskiy et al.(2013)
FOXH1_HUMAN.H11MO.0.A 		0.781 0.965
FOXH1
M09546_2.00 		Homo sapiens
NNAATMCACWNN
NNWGTGKATTNN		 Misc
Heinz et al.(2010)
hESC-FOXH1_GSE29422 		0.781 0.965
FOXH1
M10555_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$FOXH1_Q6 		0.781 0.965
For this family, TFs with SR scores > 0.664 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000036591 Forkhead 64 149

Links

Other Forkhead family TFs
Other Mus musculus TFs

Invalid Input OrderBy

35 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action