SIX2 (Bos taurus)
Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox) IPR001356 ENSBTAG00000004159 T207402_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Six2
M00425_2.00 		Mus musculus
NNAYMYNN
NNRKRTNN		 PBM
Berger et al.(2008)
Six2_2307 		0.867 1.000
SIX2
M05285_2.00 		Homo sapiens
NNYGATACSB
VSGTATCRNN		 SELEX
Yin et al.(2017)
SIX2_eDBD_HT-SELEX 		0.867 1.000
SIX2
M05287_2.00 		Homo sapiens
NSGTRWCRYN
NRYGWYACSN		 SELEX
Yin et al.(2017)
SIX2_FL_HT-SELEX 		0.867 1.000
SIX2
M08133_2.00 		Homo sapiens
NNNTGWAACCTGAKMH
DKMTCAGGTTWCANNN		 ChIP-seq
Mathelier et al.(2014)
MA1119.1 		0.867 1.000
SIX2
M09157_2.00 		Homo sapiens
DGWAAYHHGABMH
DKVTCDDRTTWCH		 Misc
Kulakovskiy et al.(2013)
SIX2_HUMAN.H11MO.0.A 		0.867 1.000
Six2
M09185_2.00 		Mus musculus
DGWAAYHYRABMYB
VRKVTYRDRTTWCH		 Misc
Kulakovskiy et al.(2013)
SIX2_MOUSE.H11MO.0.A 		0.867 1.000
SIX2
M05286_2.00 		Homo sapiens
NBRTATCRNN
NNYGATAYVN		 SELEX
Yin et al.(2017)
SIX2_eDBD_Methyl-HT-SELEX 		0.867 1.000
SIX2
M05288_2.00 		Homo sapiens
VBRTAWCRNN
NNYGWTAYVB		 SELEX
Yin et al.(2017)
SIX2_FL_Methyl-HT-SELEX 		0.867 1.000
so
M02117_2.00 		Drosophila melanogaster
NDATMYNNN
NNNRKATHN		 PBM
Weirauch et al.(2014)
pTH5690 		0.866 0.945
so
M03800_2.00 		Drosophila melanogaster
NYGATAYB
VRTATCRN		 SELEX
Nitta et al.(2015)
so_1 		0.866 0.945
so
M03801_2.00 		Drosophila melanogaster
YKATAYNNNYGATAY
RTATCRNNNRTATMR		 SELEX
Nitta et al.(2015)
so_2 		0.866 0.945
so
M03802_2.00 		Drosophila melanogaster
YGATACGTATCR
YGATACGTATCR		 SELEX
Nitta et al.(2015)
so_3 		0.866 0.945
so
M03803_2.00 		Drosophila melanogaster
RTATCRYGATAC
GTATCRYGATAY		 SELEX
Nitta et al.(2015)
so_4 		0.866 0.945
so
M06497_2.00 		Drosophila melanogaster
TGATAC
GTATCA		 B1H
Mathelier et al.(2014)
MA0246.1 		0.866 0.945
so
M06268_2.00 		Drosophila melanogaster
NRTGATA
TATCAYN		 B1H
Zhu et al.(2011)
So_Cell_FBgn0003460 		0.866 0.945
so
M06269_2.00 		Drosophila melanogaster
NNNTGATA
TATCANNN		 B1H
Zhu et al.(2011)
So_SOLEXA_FBgn0003460 		0.866 0.945
Six1
M00512_2.00 		Mus musculus
NNDATMYNNN
NNNRKATHNN		 PBM
Berger et al.(2008)
Six1_0935 		0.865 0.982
SIX1
M05094_2.00 		Homo sapiens
NNYGATACVB
VBGTATCRNN		 SELEX
Yin et al.(2017)
SIX1_eDBD_HT-SELEX 		0.865 0.982
SIX1
M05096_2.00 		Homo sapiens
NNYGATAYVB
VBRTATCRNN		 SELEX
Yin et al.(2017)
SIX1_FL_HT-SELEX 		0.865 0.982
SIX1
M08130_2.00 		Homo sapiens
GWAACCTGANM
KNTCAGGTTWC		 ChIP-seq
Mathelier et al.(2014)
MA1118.1 		0.865 0.982
SIX1
M09142_2.00 		Homo sapiens
DGWAAYHTGABMYN
NRKVTCADRTTWCH		 Misc
Kulakovskiy et al.(2013)
SIX1_HUMAN.H11MO.0.A 		0.865 0.982
Six1
M09579_2.00 		Mus musculus
GWAAYHTGABMH
DKVTCADRTTWC		 Misc
Heinz et al.(2010)
Myoblast-Six1_GSE20150 		0.865 0.982
SIX1
M10684_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SIX1_Q3_01 		0.865 0.982
SIX1
M10685_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SIX1_Q3 		0.865 0.982
SIX1
M05095_2.00 		Homo sapiens
NNYGATABNB
VNVTATCRNN		 SELEX
Yin et al.(2017)
SIX1_eDBD_Methyl-HT-SELEX 		0.865 0.982
SIX1
M05097_2.00 		Homo sapiens
NNYGATAYSB
VSRTATCRNN		 SELEX
Yin et al.(2017)
SIX1_FL_Methyl-HT-SELEX 		0.865 0.982
Six4
M00461_2.00 		Mus musculus
NNKABMHNN
NNDKVTMNN		 PBM
Berger et al.(2008)
Six4_2860 		0.708 0.709
SIX4
M04939_2.00 		Homo sapiens
NVYGATACVB
VBGTATCRBN		 SELEX
Yin et al.(2017)
SIX4_eDBD_HT-SELEX 		0.708 0.709
Six4
M09198_2.00 		Mus musculus
DGDAABHNSASNNN
NNNSTSNDVTTHCH		 Misc
Kulakovskiy et al.(2013)
SIX4_MOUSE.H11MO.0.C 		0.708 0.709
SIX4
M10646_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SIX4_Q3 		0.708 0.709
SIX4
M04940_2.00 		Homo sapiens
NBGTAWCRHN
NDYGWTACVN		 SELEX
Yin et al.(2017)
SIX4_eDBD_Methyl-HT-SELEX 		0.708 0.709
Six4
M00563_2.00 		Drosophila melanogaster
NNDANMHNN
NNDKNTHNN		 PBM
Busser et al.(2012a)
Six4 		0.708 0.673
Six4
M06530_2.00 		Drosophila melanogaster
TGABAC
GTVTCA		 B1H
Mathelier et al.(2014)
MA0204.1 		0.708 0.673
Six4
M06334_2.00 		Drosophila melanogaster
WDDTGABAC
GTVTCAHHW		 B1H
Zhu et al.(2011)
Six4_Cell_FBgn0027364 		0.708 0.673
Six4
M06335_2.00 		Drosophila melanogaster
NTGAKACB
VGTMTCAN		 B1H
Zhu et al.(2011)
Six4_SOLEXA_2_FBgn0027364 		0.708 0.673
Six4
M06336_2.00 		Drosophila melanogaster
NNNTGABA
TVTCANNN		 B1H
Zhu et al.(2011)
Six4_SOLEXA_FBgn0027364 		0.708 0.673
SIX5
M08208_2.00 		Homo sapiens
GARWTGTAGT
ACTACAWYTC		 ChIP-seq
Contrino et al.(2012)
Mv121 		0.708 0.655
SIX5
M08209_2.00 		Homo sapiens
GGAGTTGT
ACAACTCC		 ChIP-seq
Contrino et al.(2012)
Mv123 		0.708 0.655
SIX5
M10738_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SIX5_01 		0.708 0.655
SIX5
M10739_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SIX5_02 		0.708 0.655
ceh-34
M00672_2.00 		Caenorhabditis elegans
NNNRDAWNNN
NNNWTHYNNN		 PBM
Narasimhan et al.(2015)
pTH9708 		0.664 0.618
For this family, TFs with SR scores > 0.599 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSBTAP00000005445 Homeodomain 127 181

Links

Other Homeodomain family TFs
Other Bos taurus TFs

540 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
MET32 Saccharomyces cerevisiae YDR253C D
MET31 Saccharomyces cerevisiae YPL038W D
Scas_Contig568.5 Saccharomyces castellii Scas_Contig568.5 I
SKUD_191509 Saccharomyces kudriavzevii SKUD_191509 I
SU7_3598 Saccharomyces arboricola SU7_3598 I
TBLA_0A00350 Tetrapisispora blattae TBLA_0A00350 I
TDEL_0B01500 Torulaspora delbrueckii TDEL_0B01500 I
TPHA_0L01320 Tetrapisispora phaffii TPHA_0L01320 I
ZBAI_00597 Zygosaccharomyces bailii ZBAI_00597 I
ZYRO0F08162g Zygosaccharomyces rouxii ZYRO0F08162g I
SKUD_139603 Saccharomyces kudriavzevii SKUD_139603 I
Scas_Contig721.56 Saccharomyces castellii Scas_Contig721.56 I
22143_YPL038W Saccharomyces mikatae 22143_YPL038W I
23564_YPL038W Saccharomyces paradoxus 23564_YPL038W I
25018_YPL038W Saccharomyces bayanus 25018_YPL038W I
3987_YDR253C Saccharomyces mikatae 3987_YDR253C I
4678_YDR253C Saccharomyces paradoxus 4678_YDR253C I
KLTH0E11330g Kluyveromyces thermotolerans KLTH0E11330g I
Kwal_11824 Kluyveromyces waltii Kwal_11824 I
SAKL0H11440g Lachancea kluyveri SAKL0H11440g I
KLLA0_D11902g Kluyveromyces lactis KLLA0_D11902g I
BN7_573 Wickerhamomyces ciferrii BN7_573 I
KAFR_0E02900 Kazachstania africana KAFR_0E02900 I
KLTH0E11330g Lachancea thermotolerans KLTH0E11330g I
LALA0_S04e04720g Lachancea lanzarotensis LALA0_S04e04720g I
NCAS_0B02480 Naumovozyma castellii NCAS_0B02480 I
NCAS_0C02430 Naumovozyma castellii NCAS_0C02430 I
NDAI_0C05210 Naumovozyma dairenensis NDAI_0C05210 I
LELG_02390 Lodderomyces elongisporus LELG_02390 N
Kpol_1031p73 Vanderwaltozyma polyspora Kpol_1031p73 N
CLUG_05144 Candida lusitaniae CLUG_05144 N
G210_5850 Candida maltosa G210_5850 N
CTRG_02010 Candida tropicalis CTRG_02010 N
CLUG_05144 Clavispora lusitaniae CLUG_05144 N
CD36_24290 Candida dubliniensis CD36_24290 N
CaO19.9326 Candida albicans CaO19.9326 N
CaO19.1757 Candida albicans CaO19.1757 N
CAGL0L12562g Candida glabrata CAGL0L12562g N
NDAI_0E03120 Naumovozyma dairenensis NDAI_0E03120 N