CIS-BP Database: Catalog of Inferred Sequence Binding Preferences

TF Information

prd-b *(Ciona intestinalis)* Homeodomain
Pfam ID	Interpro ID	Gene ID	CIS-BP ID	Sequence source	Animal TF db
PF00046 (Homeobox)	IPR001356	ENSCING00000012765	T207857_2.00	Ensembl (2018-Dec-8)	Link out
Directly determined binding motifs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
prd-b M02077_2.00	Ciona intestinalis	NTRATTRNN	NNYAATYAN	PBM Weirauch et al.(2014) pTH6284	(Direct)	(Direct)
Motifs from related TFs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
ENSCING00000016045 M02078_2.00	Ciona intestinalis	NNYTAATTRGN	NCYAATTARNN	PBM Weirauch et al.(2014) pTH6551	0.662	0.491
Q4RRY4_TETNG M02169_2.00	Tetraodon nigroviridis	NNYAATYAN	NTRATTRNN	PBM Weirauch et al.(2014) pTH6326	0.643	0.474
SNAPOd2T00006620001 M02231_2.00	Oikopleura dioica	NTAATTRN	NYAATTAN	PBM Weirauch et al.(2014) pTH5666	0.635	0.439
A1JVI6_MOUSE M02033_2.00	Mus musculus	HTGATTGN	NCAATCAD	PBM Weirauch et al.(2014) pTH5986	0.630	0.439
ro M06495_2.00	Drosophila melanogaster	YTAATTA	TAATTAR	B1H Mathelier et al.(2014) MA0241.1	0.628	0.491
ro M06264_2.00	Drosophila melanogaster	NYTAATTA	TAATTARN	B1H Zhu et al.(2011) Ro_Cell_FBgn0003267	0.628	0.491
ro M06265_2.00	Drosophila melanogaster	HTAATTR	YAATTAD	B1H Zhu et al.(2011) Ro_SOLEXA_FBgn0003267	0.628	0.491
Duxbl1 M02099_2.00	Mus musculus	NTGATTRNN	NNYAATCAN	PBM Weirauch et al.(2014) pTH6453	0.626	0.386
ENSTNIG00000017092 M02109_2.00	Tetraodon nigroviridis	YYAATCAD	HTGATTRR	PBM Weirauch et al.(2014) pTH6064	0.623	0.386
P79681_ACIBE M02200_2.00	Acipenser baerii	DTAATTRB	VYAATTAH	PBM Weirauch et al.(2014) pTH6156	0.621	0.456
HESX1 M00309_2.00	Homo sapiens	HTAATTRGN	NCYAATTAD	PBM Barrera et al.(2016) HESX1_REF	0.621	0.421
HESX1 M00307_2.00	Homo sapiens	TAATTRNN	NNYAATTA	PBM Barrera et al.(2016) HESX1_N125S	0.621	0.421
HESX1 M00308_2.00	Homo sapiens	NATAHATRN	NYATDTATN	PBM Barrera et al.(2016) HESX1_R160C	0.621	0.404
En2 M00484_2.00	Mus musculus	NNYHATHN	NDATDRNN	PBM Berger et al.(2008) En2_0952	0.620	0.439
En1 M00519_2.00	Mus musculus	HNWTNNN	NNNAWND	PBM Berger et al.(2008) En1_3123	0.620	0.439
EN1 M03180_2.00	Homo sapiens	NNTAATTRVB	VBYAATTANN	SELEX Jolma et al.(2013) EN1_1	0.620	0.439
EN1 M03181_2.00	Homo sapiens	TAATTRSNYAATTA	TAATTRNSYAATTA	SELEX Jolma et al.(2013) EN1_2	0.620	0.439
EN1 M03182_2.00	Homo sapiens	BTAATTRN	NYAATTAV	SELEX Jolma et al.(2013) EN1_3	0.620	0.439
EN1 M03183_2.00	Homo sapiens	TDAKKRSNYMATTA	TAATKRNSYMMTHA	SELEX Jolma et al.(2013) EN1_4	0.620	0.439
EN2 M03189_2.00	Homo sapiens	NNTAATTRNN	NNYAATTANN	SELEX Jolma et al.(2013) EN2_1	0.620	0.439
EN2 M03190_2.00	Homo sapiens	VBTAATTRNN	NNYAATTAVB	SELEX Jolma et al.(2013) EN2_2	0.620	0.439
En2 M03276_2.00	Mus musculus	VBTAATTASN	NSTAATTAVB	SELEX Jolma et al.(2013) En2_1	0.620	0.439
EN1 M05218_2.00	Homo sapiens	NTAATTRV	BYAATTAN	SELEX Yin et al.(2017) EN1_eDBD_HT-SELEX	0.620	0.439
EN2 M05237_2.00	Homo sapiens	BTAATTRV	BYAATTAV	SELEX Yin et al.(2017) EN2_eDBD_HT-SELEX	0.620	0.439
EN1 M05871_2.00	Homo sapiens	VNYAATTA	TAATTRNB	SMiLE-seq Isakova et al.(2017) EN1	0.620	0.439
EN1 M10714_2.00	Homo sapiens	RTDDTBB	VVAHHAY	Transfac Matys et al.(2006) V$EN1_01	0.620	0.439
EN1 M05219_2.00	Homo sapiens	NTAAYGAB	VTCRTTAN	SELEX Yin et al.(2017) EN1_eDBD_Methyl-HT-SELEX_1	0.620	0.439
EN1 M05220_2.00	Homo sapiens	NTAATTRV	BYAATTAN	SELEX Yin et al.(2017) EN1_eDBD_Methyl-HT-SELEX_2	0.620	0.439
EN2 M05238_2.00	Homo sapiens	VHTDAYGHB	VDCRTHADB	SELEX Yin et al.(2017) EN2_eDBD_Methyl-HT-SELEX_1	0.620	0.439
EN2 M05239_2.00	Homo sapiens	BTAATTRV	BYAATTAV	SELEX Yin et al.(2017) EN2_eDBD_Methyl-HT-SELEX_2	0.620	0.439
en M03793_2.00	Drosophila melanogaster	NTAATTRN	NYAATTAN	SELEX Nitta et al.(2015) en_1	0.619	0.421
en M06485_2.00	Drosophila melanogaster	YTAATTR	YAATTAR	B1H Mathelier et al.(2014) MA0220.1	0.619	0.421
inv M06491_2.00	Drosophila melanogaster	DYTAATTR	YAATTARH	B1H Mathelier et al.(2014) MA0229.1	0.619	0.421
en M06236_2.00	Drosophila melanogaster	NYTAATTR	YAATTARN	B1H Zhu et al.(2011) En_Cell_FBgn0000577	0.619	0.421
en M06237_2.00	Drosophila melanogaster	DBTAATKR	YMATTAVH	B1H Zhu et al.(2011) en_FlyReg_FBgn0000577	0.619	0.421
en M06238_2.00	Drosophila melanogaster	NNNTAATTRN	NYAATTANNN	B1H Zhu et al.(2011) en_SOLEXA_2_FBgn0000577	0.619	0.421
en M06239_2.00	Drosophila melanogaster	NTAATTR	YAATTAN	B1H Zhu et al.(2011) En_SOLEXA_FBgn0000577	0.619	0.421
inv M06255_2.00	Drosophila melanogaster	DYTAATTR	YAATTARH	B1H Zhu et al.(2011) Inv_Cell_FBgn0001269	0.619	0.421
inv M06256_2.00	Drosophila melanogaster	NHTAATTRV	BYAATTADN	B1H Zhu et al.(2011) inv_SOLEXA_2_FBgn0001269	0.619	0.421
inv M06257_2.00	Drosophila melanogaster	NHTAATTRV	BYAATTADN	B1H Zhu et al.(2011) inv_SOLEXA_5_FBgn0001269	0.619	0.421
en M09677_2.00	Drosophila melanogaster	HTAATTRN	NYAATTAD	Misc Kulakovskiy et al.(2009) en	0.619	0.421
en M10785_2.00	Drosophila melanogaster	Transfac license required	Transfac license required	Transfac Matys et al.(2006) I$EN_Q6	0.619	0.421
ESX1 M00291_2.00	Homo sapiens	NNTRATNRN	NYNATYANN	PBM Barrera et al.(2016) ESX1_K193R	0.615	0.421
Isx M00452_2.00	Mus musculus	NNHDATNN	NNATHDNN	PBM Berger et al.(2008) Isx_3445	0.607	0.491
ISX M00319_2.00	Homo sapiens	DTAATTRK	MYAATTAH	PBM Barrera et al.(2016) ISX_REF	0.607	0.474
ISX M03218_2.00	Homo sapiens	NTAATTARATTAN	NTAATYTAATTAN	SELEX Jolma et al.(2013) ISX_1	0.607	0.474
ISX M03219_2.00	Homo sapiens	NTAATTRV	BYAATTAN	SELEX Jolma et al.(2013) ISX_2	0.607	0.474
ISX M03220_2.00	Homo sapiens	NTAATTRN	NYAATTAN	SELEX Jolma et al.(2013) ISX_3	0.607	0.474
ISX M05304_2.00	Homo sapiens	BTAATTRG	CYAATTAV	SELEX Yin et al.(2017) ISX_eDBD_HT-SELEX	0.607	0.474
ISX M05307_2.00	Homo sapiens	YTAATTRS	SYAATTAR	SELEX Yin et al.(2017) ISX_FL_HT-SELEX	0.607	0.474
ISX M00318_2.00	Homo sapiens	DTAATTRK	MYAATTAH	PBM Barrera et al.(2016) ISX_R83Q	0.607	0.474
ISX M05305_2.00	Homo sapiens	NTAATTAG	CTAATTAN	SELEX Yin et al.(2017) ISX_eDBD_Methyl-HT-SELEX_1	0.607	0.474
ISX M05306_2.00	Homo sapiens	HTAAYGHN	NDCRTTAD	SELEX Yin et al.(2017) ISX_eDBD_Methyl-HT-SELEX_2	0.607	0.474
ISX M05308_2.00	Homo sapiens	YTAATTRS	SYAATTAR	SELEX Yin et al.(2017) ISX_FL_Methyl-HT-SELEX_1	0.607	0.474
ISX M05309_2.00	Homo sapiens	HTAAYGHN	NDCRTTAD	SELEX Yin et al.(2017) ISX_FL_Methyl-HT-SELEX_2	0.607	0.474
lim-4 M02182_2.00	Caenorhabditis elegans	YTAATTRVN	NBYAATTAR	PBM Weirauch et al.(2014) pTH6366	0.604	0.351
Gbx2 M00462_2.00	Mus musculus	NNDAHNN	NNDTHNN	PBM Berger et al.(2008) Gbx2_3110	0.604	0.421
Gbx1 M00525_2.00	Mus musculus	NNTAATNR	YNATTANN	PBM Berger et al.(2008) Gbx1_2883	0.604	0.421
GBX1 M03193_2.00	Homo sapiens	NBTAATTRSB	VSYAATTAVN	SELEX Jolma et al.(2013) GBX1_1	0.604	0.421
GBX2 M03201_2.00	Homo sapiens	NNTAATTRNN	NNYAATTANN	SELEX Jolma et al.(2013) GBX2_1	0.604	0.421
GBX2 M03202_2.00	Homo sapiens	TAATTRVBCAATWA	TWATTGVBYAATTA	SELEX Jolma et al.(2013) GBX2_2	0.604	0.421
GBX2 M03203_2.00	Homo sapiens	NNTAATTRNN	NNYAATTANN	SELEX Jolma et al.(2013) GBX2_3	0.604	0.421
Gbx1 M03286_2.00	Mus musculus	NNTAATTRNN	NNYAATTANN	SELEX Jolma et al.(2013) Gbx1_1	0.604	0.421
Gbx2 M03268_2.00	Mus musculus	NNTAATTRNN	NNYAATTANN	SELEX Jolma et al.(2013) Gbx2_1	0.604	0.421
GBX2 M05265_2.00	Homo sapiens	NTAATTRN	NYAATTAN	SELEX Yin et al.(2017) GBX2_eDBD_HT-SELEX	0.604	0.421
GBX2 M05268_2.00	Homo sapiens	NTAATTRV	BYAATTAN	SELEX Yin et al.(2017) GBX2_FL_HT-SELEX	0.604	0.421
GBX2 M05266_2.00	Homo sapiens	HTAAYGAB	VTCRTTAD	SELEX Yin et al.(2017) GBX2_eDBD_Methyl-HT-SELEX_1	0.604	0.421
GBX2 M05267_2.00	Homo sapiens	NTAATTRN	NYAATTAN	SELEX Yin et al.(2017) GBX2_eDBD_Methyl-HT-SELEX_2	0.604	0.421
GBX2 M05269_2.00	Homo sapiens	NTAATTRN	NYAATTAN	SELEX Yin et al.(2017) GBX2_FL_Methyl-HT-SELEX_1	0.604	0.421
GBX2 M05270_2.00	Homo sapiens	NTAAYGAB	VTCRTTAN	SELEX Yin et al.(2017) GBX2_FL_Methyl-HT-SELEX_2	0.604	0.421
unpg M03836_2.00	Drosophila melanogaster	SSTAATYRVN	NBYRATTASS	SELEX Nitta et al.(2015) unpg_1	0.604	0.404
unpg M06517_2.00	Drosophila melanogaster	BTAATTR	YAATTAV	B1H Mathelier et al.(2014) MA0251.1	0.604	0.404
unpg M06311_2.00	Drosophila melanogaster	NBTAATTR	YAATTAVN	B1H Zhu et al.(2011) Unpg_Cell_FBgn0015561	0.604	0.404
unpg M06312_2.00	Drosophila melanogaster	HTAATTR	YAATTAD	B1H Zhu et al.(2011) Unpg_SOLEXA_FBgn0015561	0.604	0.404
al M03776_2.00	Drosophila melanogaster	TAAYBNVRTTA	TAAYBNVRTTA	SELEX Nitta et al.(2015) al_1	0.603	0.474
Pph13 M03845_2.00	Drosophila melanogaster	NTAATTRN	NYAATTAN	SELEX Nitta et al.(2015) Pph13_1	0.603	0.474
al M06477_2.00	Drosophila melanogaster	TAATTAA	TTAATTA	B1H Mathelier et al.(2014) MA0208.1	0.603	0.474
Pph13 M06522_2.00	Drosophila melanogaster	NTAATTR	YAATTAN	B1H Mathelier et al.(2014) MA0200.1	0.603	0.474
al M06212_2.00	Drosophila melanogaster	TAATTAA	TTAATTA	B1H Zhu et al.(2011) Al_Cell_FBgn0000061	0.603	0.474
al M06213_2.00	Drosophila melanogaster	NNYTAATTR	YAATTARNN	B1H Zhu et al.(2011) Al_SOLEXA_FBgn0000061	0.603	0.474
Pph13 M06321_2.00	Drosophila melanogaster	NHTAATTR	YAATTADN	B1H Zhu et al.(2011) Pph13_Cell_FBgn0023489	0.603	0.474
Pph13 M06322_2.00	Drosophila melanogaster	YTAATTR	YAATTAR	B1H Zhu et al.(2011) Pph13_SOLEXA_FBgn0023489	0.603	0.474
HESX1 M00306_2.00	Homo sapiens	WRATDRNN	NNYHATYW	PBM Barrera et al.(2016) HESX1_E149K	0.600	0.404
Awh M02121_2.00	Drosophila melanogaster	NNTAATTANN	NNTAATTANN	PBM Weirauch et al.(2014) pTH5759	0.600	0.333
Awh M03831_2.00	Drosophila melanogaster	BTAATTRV	BYAATTAV	SELEX Nitta et al.(2015) Awh_1	0.600	0.333
Awh M06513_2.00	Drosophila melanogaster	YTAATTA	TAATTAR	B1H Mathelier et al.(2014) MA0167.1	0.600	0.333
Awh M06303_2.00	Drosophila melanogaster	YTAATTA	TAATTAR	B1H Zhu et al.(2011) Awh_Cell_FBgn0013751	0.600	0.333
Awh M06304_2.00	Drosophila melanogaster	YTAATKR	YMATTAR	B1H Zhu et al.(2011) Awh_SOLEXA_FBgn0013751	0.600	0.333
PHOX2B M00282_2.00	Homo sapiens	TAATTRRY	RYYAATTA	PBM Barrera et al.(2016) PHOX2B_REF	0.599	0.456
Phox2a M00400_2.00	Mus musculus	NNHAAYNN	NNRTTDNN	PBM Berger et al.(2008) Phox2a_3947	0.599	0.456
Phox2b M00401_2.00	Mus musculus	NNHAAYNN	NNRTTDNN	PBM Berger et al.(2008) Phox2b_3948	0.599	0.456
PHOX2A M03194_2.00	Homo sapiens	TAATTRVRTTA	TAAYBYAATTA	SELEX Jolma et al.(2013) PHOX2A_1	0.599	0.456
PHOX2B M03113_2.00	Homo sapiens	TAATTRVRTTA	TAAYBYAATTA	SELEX Jolma et al.(2013) PHOX2B_1	0.599	0.456
PHOX2B M03114_2.00	Homo sapiens	TAATTRVRTTA	TAAYBYAATTA	SELEX Jolma et al.(2013) PHOX2B_2	0.599	0.456
PHOX2A M05244_2.00	Homo sapiens	NTAATTRV	BYAATTAN	SELEX Yin et al.(2017) PHOX2A_eDBD_HT-SELEX	0.599	0.456
PHOX2B M05008_2.00	Homo sapiens	BTAATYRV	BYRATTAV	SELEX Yin et al.(2017) PHOX2B_eDBD_HT-SELEX	0.599	0.456
PHOX2B M05010_2.00	Homo sapiens	TAATTWRATTA	TAATYWAATTA	SELEX Yin et al.(2017) PHOX2B_FL_HT-SELEX	0.599	0.456
Phox2a M09564_2.00	Mus musculus	NTAATBNRATTA	TAATYNVATTAN	Misc Heinz et al.(2010) Neuron-Phox2a_GSE31456	0.599	0.456
PHOX2B M00278_2.00	Homo sapiens	NNNNNRY	RYNNNNN	PBM Barrera et al.(2016) PHOX2B_Q143R	0.599	0.456
PHOX2B M00280_2.00	Homo sapiens	NNNHATAAWTDNN	NNHAWTTATDNNN	PBM Barrera et al.(2016) PHOX2B_R141G	0.599	0.456
PHOX2B M00281_2.00	Homo sapiens	NNNNNNNNRY	RYNNNNNNNN	PBM Barrera et al.(2016) PHOX2B_R141Q	0.599	0.456
PHOX2A M05245_2.00	Homo sapiens	NTAATTRV	BYAATTAN	SELEX Yin et al.(2017) PHOX2A_eDBD_Methyl-HT-SELEX	0.599	0.456
PHOX2B M05009_2.00	Homo sapiens	BTAATYRN	NYRATTAV	SELEX Yin et al.(2017) PHOX2B_eDBD_Methyl-HT-SELEX	0.599	0.456
PHOX2B M05011_2.00	Homo sapiens	TAATTHRATTA	TAATYDAATTA	SELEX Yin et al.(2017) PHOX2B_FL_Methyl-HT-SELEX	0.599	0.456
DRGX M03199_2.00	Homo sapiens	NTAATTNRATTAN	NTAATYNAATTAN	SELEX Jolma et al.(2013) DRGX_1	0.599	0.439
CG2808 M03875_2.00	Drosophila melanogaster	TAATYNSRTTA	TAAYSNRATTA	SELEX Nitta et al.(2015) CG2808_1	0.599	0.439
DRGX M05253_2.00	Homo sapiens	NTAATTRR	YYAATTAN	SELEX Yin et al.(2017) DRGX_eDBD_HT-SELEX	0.599	0.439
Drgx M10774_2.00	Rattus norvegicus	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$PRRXL1_01	0.599	0.439
DRGX M05254_2.00	Homo sapiens	NTAATTRV	BYAATTAN	SELEX Yin et al.(2017) DRGX_eDBD_Methyl-HT-SELEX	0.599	0.439
For this family, TFs with SR scores > 0.599* will likely have a similar motif*

Experimental Constructs

Motif ID	Domain	From	To	Sequence
M02077_2.00	Homeodomain	1	57	SRGRTTYSVDQITELEKLFTRNAYPTPQSRQELARNIRVPEGKVKIWFQNRRARAKK

DNA Binding Domains

Protein ID	Domain	From	To	Sequence
ENSCINP00000023689	Homeodomain	153	209	SRGRTTYSVDQITELEKLFTRNAYPTPQSRQELARNIRVPEGKVKIWFQNRRARAKK

Links
Other Homeodomain family TFs
Other *Ciona intestinalis* TFs

1325 Related TFs

Name	Species	Gene ID	Motif Evidence	SR Score	Action
ENSPFOG00000017914	Poecilia formosa	ENSPFOG00000017914	I
ENSDORG00000013398	Dipodomys ordii	ENSDORG00000013398	N
GLIS3	Meleagris gallopavo	ENSMGAG00000005243	N
ENSONIG00000018351	Oreochromis niloticus	ENSONIG00000018351	N
ENSSHAG00000001848	Sarcophilus harrisii	ENSSHAG00000001848	N

prd-b (Ciona intestinalis) Homeodomain

TF Information

Directly determined binding motifs

Motifs from related TFs

Experimental Constructs

DNA Binding Domains

Links

1325 Related TFs

prd-b **(Ciona intestinalis)
Homeodomain**