CIS-BP Database: Catalog of Inferred Sequence Binding Preferences

TF Information

Tgif1 *(Mus musculus)* Homeodomain
Pfam ID	Interpro ID	Gene ID	CIS-BP ID	Sequence source	Animal TF db
PF00046 (Homeobox)	IPR001356	ENSMUSG00000047407	T212524_2.00	Ensembl (2018-Dec-8)	Link out
Directly determined binding motifs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
Tgif1 M00500_2.00	Mus musculus	NNTGACANNN	NNNTGTCANN	PBM Berger et al.(2008) Tgif1_2342	(Direct)	(Direct)
Tgif1 M09211_2.00	Mus musculus	TGACAGBNV	BNVCTGTCA	Misc Kulakovskiy et al.(2013) TGIF1_MOUSE.H11MO.0.A	(Direct)	(Direct)
Motifs from related TFs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
TGIF1 M03223_2.00	Homo sapiens	TGACAGCTGTCA	TGACAGCTGTCA	SELEX Jolma et al.(2013) TGIF1_1	0.867	1.000
TGIF1 M05317_2.00	Homo sapiens	TGACAGSTGTCA	TGACASCTGTCA	SELEX Yin et al.(2017) TGIF1_eDBD_HT-SELEX	0.348	1.000
TGIF1 M09159_2.00	Homo sapiens	TGACAGS	SCTGTCA	Misc Kulakovskiy et al.(2013) TGIF1_HUMAN.H11MO.0.A	0.348	1.000
TGIF1 M10740_2.00	Homo sapiens	WHNTGACARST	ASYTGTCANDW	Transfac Matys et al.(2006) V$TGIF_01	0.867	1.000
TGIF1 M05318_2.00	Homo sapiens	TGACAKVTGTCA	TGACABMTGTCA	SELEX Yin et al.(2017) TGIF1_eDBD_Methyl-HT-SELEX	0.328	1.000
Tgif2 M00521_2.00	Mus musculus	NNTGACANNN	NNNTGTCANN	PBM Berger et al.(2008) Tgif2_3451	0.809	0.836
TGIF2 M03123_2.00	Homo sapiens	TGACAGSTGTCA	TGACASCTGTCA	SELEX Jolma et al.(2013) TGIF2_1	0.809	0.836
TGIF2 M05032_2.00	Homo sapiens	TGACABVTGTCA	TGACABVTGTCA	SELEX Yin et al.(2017) TGIF2_eDBD_HT-SELEX	0.809	0.836
TGIF2 M05034_2.00	Homo sapiens	DTGACANN	NNTGTCAH	SELEX Yin et al.(2017) TGIF2_FL_HT-SELEX	0.809	0.836
TGIF2 M05033_2.00	Homo sapiens	TGWCABVTGWCA	TGWCABVTGWCA	SELEX Yin et al.(2017) TGIF2_eDBD_Methyl-HT-SELEX	0.809	0.836
TGIF2 M05035_2.00	Homo sapiens	DTGACANN	NNTGTCAH	SELEX Yin et al.(2017) TGIF2_FL_Methyl-HT-SELEX	0.809	0.836
achi M03860_2.00	Drosophila melanogaster	TGACAD	HTGTCA	SELEX Nitta et al.(2015) achi_1	0.767	0.727
achi M03861_2.00	Drosophila melanogaster	TGACAGMTGTCA	TGACAKCTGTCA	SELEX Nitta et al.(2015) achi_2	0.767	0.727
achi M03862_2.00	Drosophila melanogaster	TGACAGNNNNNNYGTCA	TGACRNNNNNNCTGTCA	SELEX Nitta et al.(2015) achi_3	0.767	0.727
vis M03859_2.00	Drosophila melanogaster	TGACAS	STGTCA	SELEX Nitta et al.(2015) vis_1	0.767	0.727
vis M06534_2.00	Drosophila melanogaster	TGACAB	BTGTCA	B1H Mathelier et al.(2014) MA0252.1	0.767	0.727
achi M06535_2.00	Drosophila melanogaster	TGACAG	CTGTCA	B1H Mathelier et al.(2014) MA0207.1	0.767	0.727
achi M06345_2.00	Drosophila melanogaster	TGTCADW	WHTGACA	B1H Zhu et al.(2011) Achi_Cell_FBgn0033749	0.767	0.727
achi M06346_2.00	Drosophila melanogaster	HTGACA	TGTCAD	B1H Zhu et al.(2011) Achi_SOLEXA_FBgn0033749	0.767	0.727
vis M06343_2.00	Drosophila melanogaster	TGTCA	TGACA	B1H Zhu et al.(2011) Vis_Cell_FBgn0033748	0.767	0.727
vis M06344_2.00	Drosophila melanogaster	TGTCAD	HTGACA	B1H Zhu et al.(2011) Vis_SOLEXA_FBgn0033748	0.767	0.727
unc-62 M02185_2.00	Caenorhabditis elegans	NHDAHANNN	NNNTDTHDN	PBM Weirauch et al.(2014) pTH5781	0.652	0.509
Pknox2 M00468_2.00	Mus musculus	NNNGACRNNN	NNNYGTCNNN	PBM Berger et al.(2008) Pknox2_3077	0.631	0.527
PKNOX2 M03195_2.00	Homo sapiens	TGACAGSTGTCA	TGACASCTGTCA	SELEX Jolma et al.(2013) PKNOX2_1	0.631	0.527
Pknox2 M03270_2.00	Mus musculus	TGACAGSTGTCA	TGACASCTGTCA	SELEX Jolma et al.(2013) Pknox2_1	0.631	0.527
PKNOX2 M05246_2.00	Homo sapiens	TGACABVTGTCA	TGACABVTGTCA	SELEX Yin et al.(2017) PKNOX2_eDBD_HT-SELEX	0.631	0.527
PKNOX2 M05247_2.00	Homo sapiens	TGACASSTGTCA	TGACASSTGTCA	SELEX Yin et al.(2017) PKNOX2_eDBD_Methyl-HT-SELEX	0.631	0.527
Pknox1 M00399_2.00	Mus musculus	HGACRNNN	NNNYGTCD	PBM Berger et al.(2008) Pknox1_2364	0.631	0.509
PKNOX1 M03178_2.00	Homo sapiens	TGACAGSTGTCA	TGACASCTGTCA	SELEX Jolma et al.(2013) PKNOX1_1	0.631	0.509
PKNOX1 M05206_2.00	Homo sapiens	TGACASSTGTCA	TGACASSTGTCA	SELEX Yin et al.(2017) PKNOX1_eDBD_HT-SELEX	0.631	0.509
PKNOX1 M05208_2.00	Homo sapiens	TGACAGCTGTCA	TGACAGCTGTCA	SELEX Yin et al.(2017) PKNOX1_FL_HT-SELEX	0.631	0.509
PKNOX1 M09150_2.00	Homo sapiens	TGABTGRCRGV	BCYGYCAVTCA	Misc Kulakovskiy et al.(2013) PKNX1_HUMAN.H11MO.0.B	0.631	0.509
Pknox1 M09175_2.00	Mus musculus	TGABTGRCRGV	BCYGYCAVTCA	Misc Kulakovskiy et al.(2013) PKNX1_MOUSE.H11MO.0.A	0.631	0.509
PKNOX1 M10712_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$PREP1_Q3	0.631	0.509
PKNOX1 M05207_2.00	Homo sapiens	YGWCASSTGWCR	YGWCASSTGWCR	SELEX Yin et al.(2017) PKNOX1_eDBD_Methyl-HT-SELEX	0.631	0.509
PKNOX1 M05209_2.00	Homo sapiens	TGACABVTGTCA	TGACABVTGTCA	SELEX Yin et al.(2017) PKNOX1_FL_Methyl-HT-SELEX	0.631	0.509
TGIF2LX M03171_2.00	Homo sapiens	TGACAGSTGTCA	TGACASCTGTCA	SELEX Jolma et al.(2013) TGIF2LX_1	0.628	0.673
TGIF2LX M05191_2.00	Homo sapiens	TGACABVTGTCA	TGACABVTGTCA	SELEX Yin et al.(2017) TGIF2LX_eDBD_HT-SELEX	0.628	0.673
TGIF2LX M05193_2.00	Homo sapiens	TGACASSTGTCA	TGACASSTGTCA	SELEX Yin et al.(2017) TGIF2LX_FL_HT-SELEX	0.628	0.673
TGIF2LX M05192_2.00	Homo sapiens	TGACABVTGTCA	TGACABVTGTCA	SELEX Yin et al.(2017) TGIF2LX_eDBD_Methyl-HT-SELEX	0.628	0.673
TGIF2LX M05194_2.00	Homo sapiens	TGACASSTGTCA	TGACASSTGTCA	SELEX Yin et al.(2017) TGIF2LX_FL_Methyl-HT-SELEX	0.628	0.673
TGIF2LY M05313_2.00	Homo sapiens	TGACABVTGTCA	TGACABVTGTCA	SELEX Yin et al.(2017) TGIF2LY_eDBD_HT-SELEX	0.628	0.655
TGIF2LY M05314_2.00	Homo sapiens	YGACABVTGTCR	YGACABVTGTCR	SELEX Yin et al.(2017) TGIF2LY_eDBD_Methyl-HT-SELEX	0.628	0.655
hth M06490_2.00	Drosophila melanogaster	TGACAK	MTGTCA	B1H Mathelier et al.(2014) MA0227.1	0.624	0.545
hth M06252_2.00	Drosophila melanogaster	TGTCA	TGACA	B1H Zhu et al.(2011) Hth_Cell_FBgn0001235	0.624	0.545
hth M06253_2.00	Drosophila melanogaster	NNTGACAD	HTGTCANN	B1H Zhu et al.(2011) hth_SOLEXA_2_FBgn0001235	0.624	0.545
hth M06254_2.00	Drosophila melanogaster	NTGACA	TGTCAN	B1H Zhu et al.(2011) Hth_SOLEXA_FBgn0001235	0.624	0.545
Meis1 M00407_2.00	Mus musculus	NTGACADNN	NNHTGTCAN	PBM Berger et al.(2008) Meis1_2335	0.624	0.527
Meis2 M00437_2.00	Mus musculus	NTGACANNN	NNNTGTCAN	PBM Berger et al.(2008) Mrg1_2246	0.624	0.527
Meis3 M00488_2.00	Mus musculus	NTGACANNN	NNNTGTCAN	PBM Berger et al.(2008) Mrg2_2302	0.624	0.527
MEIS1 M03165_2.00	Homo sapiens	NTGACAN	NTGTCAN	SELEX Jolma et al.(2013) MEIS1_1	0.624	0.527
MEIS2 M03147_2.00	Homo sapiens	WTGACAGSTGTCAM	KTGACASCTGTCAW	SELEX Jolma et al.(2013) MEIS2_1	0.624	0.527
MEIS2 M03148_2.00	Homo sapiens	DTGACAGS	SCTGTCAH	SELEX Jolma et al.(2013) MEIS2_2	0.624	0.527
Meis2 M03261_2.00	Mus musculus	NTGACAN	NTGTCAN	SELEX Jolma et al.(2013) Meis2_1	0.624	0.527
Meis2 M03262_2.00	Mus musculus	TGACAGSTGTCA	TGACASCTGTCA	SELEX Jolma et al.(2013) Meis2_2	0.624	0.527
Meis3 M03279_2.00	Mus musculus	NTGACAN	NTGTCAN	SELEX Jolma et al.(2013) Meis3_1	0.624	0.527
Meis3 M03280_2.00	Mus musculus	TGACAGSTGTCA	TGACASCTGTCA	SELEX Jolma et al.(2013) Meis3_2	0.624	0.527
MEIS2 M02740_2.00	Homo sapiens	TGACASSTGTC	GACASSTGTCA	SELEX Jolma et al.(2010) MEIS2_dimer	0.624	0.527
MEIS2 M02741_2.00	Homo sapiens	GGACAKNT	ANMTGTCC	SELEX Jolma et al.(2010) MEIS2_monomer	0.624	0.527
MEIS2 M05138_2.00	Homo sapiens	TGACASSTGTCA	TGACASSTGTCA	SELEX Yin et al.(2017) MEIS2_eDBD_HT-SELEX	0.624	0.527
MEIS2 M05140_2.00	Homo sapiens	TGACASSTGTCA	TGACASSTGTCA	SELEX Yin et al.(2017) MEIS2_FL_HT-SELEX	0.624	0.527
MEIS1 M09148_2.00	Homo sapiens	NTGATTDATDDB	VHHATHAATCAN	Misc Kulakovskiy et al.(2013) MEIS1_HUMAN.H11MO.0.A	0.624	0.527
MEIS2 M09143_2.00	Homo sapiens	HTGACAGBTKTBM	KVAMAVCTGTCAD	Misc Kulakovskiy et al.(2013) MEIS2_HUMAN.H11MO.0.B	0.624	0.527
Meis1 M09178_2.00	Mus musculus	NTGATTDATDDB	VHHATHAATCAN	Misc Kulakovskiy et al.(2013) MEIS1_MOUSE.H11MO.0.A	0.624	0.527
Meis2 M09189_2.00	Mus musculus	HTGACAGBTKTBM	KVAMAVCTGTCAD	Misc Kulakovskiy et al.(2013) MEIS2_MOUSE.H11MO.0.B	0.624	0.527
Meis1 M09568_2.00	Mus musculus	VBTGWCASNN	NNSTGWCAVB	Misc Heinz et al.(2010) MastCells-Meis1_GSE48085	0.624	0.527
MEIS1 M10709_2.00	Homo sapiens	NHNTGACAGNDN	NHNCTGTCANDN	Transfac Matys et al.(2006) V$MEIS1_01	0.624	0.527
MEIS1 M10710_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$MEIS1_06	0.624	0.527
MEIS2 M05139_2.00	Homo sapiens	YGACASSYGHCR	YGDCRSSTGTCR	SELEX Yin et al.(2017) MEIS2_eDBD_Methyl-HT-SELEX	0.624	0.527
MEIS2 M05141_2.00	Homo sapiens	TGACASSTGTCA	TGACASSTGTCA	SELEX Yin et al.(2017) MEIS2_FL_Methyl-HT-SELEX	0.624	0.527
For this family, TFs with SR scores > 0.599* will likely have a similar motif*

Experimental Constructs

Motif ID	Domain	From	To	Sequence
M00500_2.00	Homeodomain	17	74	RRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRRL

DNA Binding Domains

Protein ID	Domain	From	To	Sequence
ENSMUSP00000060512	Homeodomain	36	93	RRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRRL
ENSMUSP00000113192	Homeodomain	16	73	RRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRRL
ENSMUSP00000115375	Homeodomain	16	73	RRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRRL
ENSMUSP00000124168	Homeodomain	16	73	RRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRRL
ENSMUSP00000124970	Homeodomain	7	53	RRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQN
ENSMUSP00000125247	Homeodomain	16	58	RRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLS
ENSMUSP00000127139	Homeodomain	16	73	RRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRRL
ENSMUSP00000130930	Homeodomain	69	126	RRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRRL
ENSMUSP00000139438	Homeodomain	36	81	RRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQ

Links
Other Homeodomain family TFs
Other *Mus musculus* TFs

816 Related TFs

Name	Species	Gene ID	Motif Evidence	SR Score	Action

Tgif1 (Mus musculus) Homeodomain

TF Information

Directly determined binding motifs

Motifs from related TFs

Experimental Constructs

DNA Binding Domains

Links

816 Related TFs

Tgif1 **(Mus musculus)
Homeodomain**