CIS-BP Database: Catalog of Inferred Sequence Binding Preferences

TF Information

ISL1 *(Procavia capensis)* Homeodomain
Pfam ID	Interpro ID	Gene ID	CIS-BP ID	Sequence source	Animal TF db
PF00046 (Homeobox)	IPR001356	ENSPCAG00000013037	T214288_2.00	Ensembl (2018-Dec-8)	Link out
Directly determined binding motifs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
No direct experiments
Motifs from related TFs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
Isl2 M00458_2.00	Mus musculus	NWDWDNN	NNHWHWN	PBM Berger et al.(2008) Isl2_3430	0.867	1.000
ISL2 M03177_2.00	Homo sapiens	YTAAKTGB	VCAMTTAR	SELEX Jolma et al.(2013) ISL2_1	0.867	1.000
ISL1 M04908_2.00	Homo sapiens	BTAAKTGS	SCAMTTAV	SELEX Yin et al.(2017) ISL1_eDBD_HT-SELEX	0.867	1.000
ISL1 M04910_2.00	Homo sapiens	NTAAKTGS	SCAMTTAN	SELEX Yin et al.(2017) ISL1_FL_HT-SELEX	0.867	1.000
ISL2 M05204_2.00	Homo sapiens	NTAAKTGS	SCAMTTAN	SELEX Yin et al.(2017) ISL2_eDBD_HT-SELEX	0.867	1.000
ISL1 M09128_2.00	Homo sapiens	NYWRAKKGV	BCMMTYWRN	Misc Kulakovskiy et al.(2013) ISL1_HUMAN.H11MO.0.A	0.867	1.000
Isl1 M09209_2.00	Mus musculus	NYWRAKKGV	BCMMTYWRN	Misc Kulakovskiy et al.(2013) ISL1_MOUSE.H11MO.0.A	0.867	1.000
Isl1 M09578_2.00	Mus musculus	YTAAKKGV	BCMMTTAR	Misc Heinz et al.(2010) Neuron-Isl1_GSE31456	0.867	1.000
ISL1 M10634_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$ISL1_Q3	0.867	1.000
ISL1 M10635_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$ISL1_Q6	0.867	1.000
ISL1 M04909_2.00	Homo sapiens	BTAAKTGS	SCAMTTAV	SELEX Yin et al.(2017) ISL1_eDBD_Methyl-HT-SELEX	0.867	1.000
ISL1 M04911_2.00	Homo sapiens	BTAAKTGS	SCAMTTAV	SELEX Yin et al.(2017) ISL1_FL_Methyl-HT-SELEX	0.867	1.000
ISL2 M05205_2.00	Homo sapiens	NTAAKTGN	NCAMTTAN	SELEX Yin et al.(2017) ISL2_eDBD_Methyl-HT-SELEX	0.867	1.000
ISL2B_ONCTS M10798_2.00	Oncorhynchus tshawytscha	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$ISL2_02	0.866	0.982
ISL2B_ONCTS M10799_2.00	Oncorhynchus tshawytscha	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$ISL2_03	0.866	0.982
ISL2B_ONCTS M10800_2.00	Oncorhynchus tshawytscha	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$ISL2_04	0.866	0.982
ISL2B_ONCTS M10801_2.00	Oncorhynchus tshawytscha	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$ISL2_05	0.866	0.982
tup M06498_2.00	Drosophila melanogaster	WTAATKG	CMATTAW	B1H Mathelier et al.(2014) MA0248.1	0.864	0.965
tup M06270_2.00	Drosophila melanogaster	SWTAATKG	CMATTAWS	B1H Zhu et al.(2011) Tup_Cell_FBgn0003896	0.864	0.965
tup M06271_2.00	Drosophila melanogaster	NYTAATKRV	BYMATTARN	B1H Zhu et al.(2011) tup_SOLEXA_10_FBgn0003896	0.864	0.965
tup M06272_2.00	Drosophila melanogaster	YTAATKR	YMATTAR	B1H Zhu et al.(2011) Tup_SOLEXA_FBgn0003896	0.864	0.965
CBG04010 M01242_2.00	Caenorhabditis briggsae	NNKTAATDDMN	NKHHATTAMNN	PBM Lambert et al.(2019) pTH11489	0.835	0.772
NEMVEDRAFT_v1g81309 M02152_2.00	Nematostella vectensis	NTAATDNNN	NNNHATTAN	PBM Weirauch et al.(2014) pTH5477	0.636	0.351
NOTO M03241_2.00	Homo sapiens	NNTAATKWRN	NYWMATTANN	SELEX Jolma et al.(2013) NOTO_1	0.631	0.368
NOTO M05390_2.00	Homo sapiens	BTAATKRV	BYMATTAV	SELEX Yin et al.(2017) NOTO_eDBD_HT-SELEX	0.631	0.368
NOTO M05391_2.00	Homo sapiens	BTMATKRV	BYMATKAV	SELEX Yin et al.(2017) NOTO_eDBD_Methyl-HT-SELEX	0.631	0.368
PHOX2B M00278_2.00	Homo sapiens	NNNNNRY	RYNNNNN	PBM Barrera et al.(2016) PHOX2B_Q143R	0.623	0.368
Noto M02101_2.00	Mus musculus	NNHHATDDNN	NNHHATDDNN	PBM Weirauch et al.(2014) pTH6268	0.613	0.351
VSX1 M00269_2.00	Homo sapiens	NNWAAYNNN	NNNRTTWNN	PBM Barrera et al.(2016) VSX1_REF	0.608	0.386
Vsx1 M00459_2.00	Mus musculus	NNTAATDDN	NHHATTANN	PBM Berger et al.(2008) Vsx1_1728	0.608	0.386
Vsx1 M03267_2.00	Mus musculus	NTAATTRN	NYAATTAN	SELEX Jolma et al.(2013) Vsx1_1	0.608	0.386
VSX1 M00266_2.00	Homo sapiens	NNTAAYNNN	NNNRTTANN	PBM Barrera et al.(2016) VSX1_G160D	0.608	0.386
Sebox M02097_2.00	Mus musculus	NHTTAATTAN	NTAATTAADN	PBM Weirauch et al.(2014) pTH6379	0.605	0.421
ceh-5 M02179_2.00	Caenorhabditis elegans	NNTAATDDN	NHHATTANN	PBM Weirauch et al.(2014) pTH6562	0.604	0.368
SHOX M02095_2.00	Homo sapiens	NTAATTRN	NYAATTAN	PBM Weirauch et al.(2014) pTH5805	0.601	0.404
Shox2 M00439_2.00	Mus musculus	NTAATDDN	NHHATTAN	PBM Berger et al.(2008) Shox2_2641	0.601	0.404
SHOX M03232_2.00	Homo sapiens	NTAATTRN	NYAATTAN	SELEX Jolma et al.(2013) SHOX_1	0.601	0.404
SHOX2 M03204_2.00	Homo sapiens	BTAATTRN	NYAATTAV	SELEX Jolma et al.(2013) SHOX2_1	0.601	0.404
Shox2 M03263_2.00	Mus musculus	NTAATTRN	NYAATTAN	SELEX Jolma et al.(2013) Shox2_1	0.601	0.404
CG5369 M03876_2.00	Drosophila melanogaster	TAATTHVATTA	TAATBDAATTA	SELEX Nitta et al.(2015) CG5369_1	0.601	0.404
CG5369 M03877_2.00	Drosophila melanogaster	TAATTRNNTAATBN	NVATTANNYAATTA	SELEX Nitta et al.(2015) CG5369_2	0.601	0.404
CG5369 M03878_2.00	Drosophila melanogaster	TAATTVRATWA	TWATYBAATTA	SELEX Nitta et al.(2015) CG5369_3	0.601	0.404
SHOX M05366_2.00	Homo sapiens	NTAATTRV	BYAATTAN	SELEX Yin et al.(2017) SHOX_eDBD_HT-SELEX	0.601	0.404
Shox2 M10772_2.00	Rattus norvegicus	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$SHOX2_05	0.601	0.404
SHOX M05367_2.00	Homo sapiens	NTAATTRV	BYAATTAN	SELEX Yin et al.(2017) SHOX_eDBD_Methyl-HT-SELEX_1	0.601	0.404
SHOX M05368_2.00	Homo sapiens	NTAAYGAN	NTCRTTAN	SELEX Yin et al.(2017) SHOX_eDBD_Methyl-HT-SELEX_2	0.601	0.404
C4B866_NEMVE M02052_2.00	Nematostella vectensis	NNTTAATTARNN	NNYTAATTAANN	PBM Weirauch et al.(2014) pTH6176	0.600	0.421
For this family, TFs with SR scores > 0.599* will likely have a similar motif*

DNA Binding Domains

Protein ID	Domain	From	To	Sequence
ENSPCAP00000012168	Homeodomain	181	237	TRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKK

Links
Other Homeodomain family TFs
Other *Procavia capensis* TFs

604 Related TFs

Name	Species	Gene ID	Motif Evidence	SR Score	Action
PV08_11376	Exophiala spinifera	PV08_11376	N	0.000
MAM_02763	Metarhizium album	MAM_02763	N	0.000
MANI_026709	Metarhizium anisopliae	MANI_026709	N	0.000
MBM_05804	Marssonina brunnea	MBM_05804	N	0.000
MBR_02363	Metarhizium brunneum	MBR_02363	N	0.000
MGU_00675	Metarhizium guizhouense	MGU_00675	N	0.000
NechaG66814	Fusarium solani	NechaG66814	N	0.000
OIDMADRAFT_41356	Oidiodendron maius	OIDMADRAFT_41356	N	0.000
PAAG_04399	Paracoccidioides sp lutzii	PAAG_04399	N	0.000
PABG_04201	Paracoccidioides brasiliensis	PABG_04201	N	0.000
PMAA_027450	Talaromyces marneffei	PMAA_027450	N	0.000
PV04_06890	Capronia semiimmersa	PV04_06890	N	0.000
PV05_09061	Exophiala xenobiotica	PV05_09061	N	0.000
PV06_02579	Exophiala oligosperma	PV06_02579	N	0.000
PV07_03724	Cladophialophora immunda	PV07_03724	N	0.000
PV07_12548	Cladophialophora immunda	PV07_12548	N	0.000
MAJ_00301	Metarhizium majus	MAJ_00301	N	0.000
PV10_08689	Exophiala mesophila	PV10_08689	N	0.000
PV11_06703	Exophiala sideris	PV11_06703	N	0.000
PVAR5_4132	Byssochlamys spectabilis	PVAR5_4132	N	0.000
SBOR_0679	Sclerotinia borealis	SBOR_0679	N	0.000
SPBR_01645	Sporothrix brasiliensis	SPBR_01645	N	0.000
SS1G_04655	Sclerotinia sclerotiorum	SS1G_04655	N	0.000
TSTA_071310	Talaromyces stipitatus	TSTA_071310	N	0.000
VHEMI03871	Torrubiella hemipterigena	VHEMI03871	N	0.000
X797_000370	Metarhizium robertsii	X797_000370	N	0.000
Z517_00960	Fonsecaea pedrosoi	Z517_00960	N	0.000
Z518_02769	Rhinocladiella mackenziei	Z518_02769	N	0.000
Z519_03993	Cladophialophora bantiana	Z519_03993	N	0.000
estExt_Genewise1Plus.C_sca_18_chr2_1_02126	Nectria haematococca	estExt_Genewise1Plus.C_sca_18_chr2_1_02126	N	0.000
fgenesh1_pg.00609_#_575	Aspergillus carbonarius	fgenesh1_pg.00609_#_575	N	0.000
PMAA_027450	Penicillium marneffei	PMAA_027450	N	0.000
NFIA_109970	Neosartorya fischeri	CADNFIAG00009928	N	0.000
A1O3_05959	Capronia epimyces	A1O3_05959	N	0.000
A1O5_08664	Cladophialophora psammophila	A1O5_08664	N	0.000
A1O7_06479	Cladophialophora yegresii	A1O7_06479	N	0.000
A1O9_08053	Exophiala aquamarina	A1O9_08053	N	0.000
ACRE_051010	Acremonium chrysogenum	ACRE_051010	N	0.000
BBA_03393	Beauveria bassiana	BBA_03393	N	0.000
Bcin01g08080	Botrytis cinerea	Bcin01g08080	N	0.000
BDDG_08069	Blastomyces dermatitidis	BDDG_08069	N	0.000
ACLA_045490	Aspergillus clavatus	CADACLAG00004978	N	0.000
CADAFLAG00005113	Aspergillus flavus	CADAFLAG00005113	N	0.000
AFUA_4G06170	Aspergillus fumigatus	CADAFUAG00008511	N	0.000
CADANGAG00003756	Aspergillus niger	CADANGAG00003756	N	0.000
ANIA_04324	Aspergillus nidulans	CADANIAG00006139	N	0.000
CADAORAG00008051	Aspergillus oryzae	CADAORAG00008051	N	0.000
ATEG_06807	Aspergillus terreus	CADATEAG00006231	N	0.000
A1O1_06448	Capronia coronata	A1O1_06448	N	0.000
CCM_00337	Cordyceps militaris	CCM_00337	N	0.000
CPUR_04232	Claviceps purpurea	CPUR_04232	N	0.000
EURHEDRAFT_516818	Aspergillus ruber	EURHEDRAFT_516818	N	0.000
FFUJ_04132	Fusarium fujikuroi	FFUJ_04132	N	0.000
FGRRES_09277	Fusarium graminearum	FGRRES_09277	N	0.000
FOXG_14212	Fusarium oxysporum	FOXG_14212	N	0.000
FPSE_09669	Fusarium pseudograminearum	FPSE_09669	N	0.000
G647_06053	Cladophialophora carrionii	G647_06053	N	0.000
GMDG_03916	Pseudogymnoascus destructans	GMDG_03916	N	0.000
GSTUM_00009240001	Tuber melanosporum	GSTUM_00009240001	N	0.000
HCBG_02231	Histoplasma capsulatum	HCBG_02231	N	0.000
HMPREF1120_03961	Exophiala dermatitidis	HMPREF1120_03961	N	0.000
HMPREF1624_03632	Sporothrix schenckii	HMPREF1624_03632	N	0.000
MAC_08284	Metarhizium acridum	MAC_08284	N	0.000

ISL1 (Procavia capensis) Homeodomain

TF Information

Directly determined binding motifs

Motifs from related TFs

DNA Binding Domains

Links

604 Related TFs

ISL1 **(Procavia capensis)
Homeodomain**