ML223533a (Mnemiopsis leidyi)
Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox) IPR001356 ML223533a T220665_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Six2
M00425_2.00 		Mus musculus
NNAYMYNN
NNRKRTNN		 PBM
Berger et al.(2008)
Six2_2307 		0.853 0.945
Six1
M00512_2.00 		Mus musculus
NNDATMYNNN
NNNRKATHNN		 PBM
Berger et al.(2008)
Six1_0935 		0.853 0.945
SIX1
M05094_2.00 		Homo sapiens
NNYGATACVB
VBGTATCRNN		 SELEX
Yin et al.(2017)
SIX1_eDBD_HT-SELEX 		0.853 0.945
SIX1
M05096_2.00 		Homo sapiens
NNYGATAYVB
VBRTATCRNN		 SELEX
Yin et al.(2017)
SIX1_FL_HT-SELEX 		0.853 0.945
SIX2
M05285_2.00 		Homo sapiens
NNYGATACSB
VSGTATCRNN		 SELEX
Yin et al.(2017)
SIX2_eDBD_HT-SELEX 		0.853 0.945
SIX2
M05287_2.00 		Homo sapiens
NSGTRWCRYN
NRYGWYACSN		 SELEX
Yin et al.(2017)
SIX2_FL_HT-SELEX 		0.853 0.945
SIX1
M08130_2.00 		Homo sapiens
GWAACCTGANM
KNTCAGGTTWC		 ChIP-seq
Mathelier et al.(2014)
MA1118.1 		0.853 0.945
SIX2
M08133_2.00 		Homo sapiens
NNNTGWAACCTGAKMH
DKMTCAGGTTWCANNN		 ChIP-seq
Mathelier et al.(2014)
MA1119.1 		0.853 0.945
SIX1
M09142_2.00 		Homo sapiens
DGWAAYHTGABMYN
NRKVTCADRTTWCH		 Misc
Kulakovskiy et al.(2013)
SIX1_HUMAN.H11MO.0.A 		0.853 0.945
SIX2
M09157_2.00 		Homo sapiens
DGWAAYHHGABMH
DKVTCDDRTTWCH		 Misc
Kulakovskiy et al.(2013)
SIX2_HUMAN.H11MO.0.A 		0.853 0.945
Six2
M09185_2.00 		Mus musculus
DGWAAYHYRABMYB
VRKVTYRDRTTWCH		 Misc
Kulakovskiy et al.(2013)
SIX2_MOUSE.H11MO.0.A 		0.853 0.945
Six1
M09579_2.00 		Mus musculus
GWAAYHTGABMH
DKVTCADRTTWC		 Misc
Heinz et al.(2010)
Myoblast-Six1_GSE20150 		0.853 0.945
SIX1
M10684_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SIX1_Q3_01 		0.853 0.945
SIX1
M10685_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SIX1_Q3 		0.853 0.945
SIX1
M05095_2.00 		Homo sapiens
NNYGATABNB
VNVTATCRNN		 SELEX
Yin et al.(2017)
SIX1_eDBD_Methyl-HT-SELEX 		0.853 0.945
SIX1
M05097_2.00 		Homo sapiens
NNYGATAYSB
VSRTATCRNN		 SELEX
Yin et al.(2017)
SIX1_FL_Methyl-HT-SELEX 		0.853 0.945
SIX2
M05286_2.00 		Homo sapiens
NBRTATCRNN
NNYGATAYVN		 SELEX
Yin et al.(2017)
SIX2_eDBD_Methyl-HT-SELEX 		0.853 0.945
SIX2
M05288_2.00 		Homo sapiens
VBRTAWCRNN
NNYGWTAYVB		 SELEX
Yin et al.(2017)
SIX2_FL_Methyl-HT-SELEX 		0.853 0.945
so
M02117_2.00 		Drosophila melanogaster
NDATMYNNN
NNNRKATHN		 PBM
Weirauch et al.(2014)
pTH5690 		0.852 0.927
so
M03800_2.00 		Drosophila melanogaster
NYGATAYB
VRTATCRN		 SELEX
Nitta et al.(2015)
so_1 		0.852 0.927
so
M03801_2.00 		Drosophila melanogaster
YKATAYNNNYGATAY
RTATCRNNNRTATMR		 SELEX
Nitta et al.(2015)
so_2 		0.852 0.927
so
M03802_2.00 		Drosophila melanogaster
YGATACGTATCR
YGATACGTATCR		 SELEX
Nitta et al.(2015)
so_3 		0.852 0.927
so
M03803_2.00 		Drosophila melanogaster
RTATCRYGATAC
GTATCRYGATAY		 SELEX
Nitta et al.(2015)
so_4 		0.852 0.927
so
M06497_2.00 		Drosophila melanogaster
TGATAC
GTATCA		 B1H
Mathelier et al.(2014)
MA0246.1 		0.852 0.927
so
M06268_2.00 		Drosophila melanogaster
NRTGATA
TATCAYN		 B1H
Zhu et al.(2011)
So_Cell_FBgn0003460 		0.852 0.927
so
M06269_2.00 		Drosophila melanogaster
NNNTGATA
TATCANNN		 B1H
Zhu et al.(2011)
So_SOLEXA_FBgn0003460 		0.852 0.927
Six4
M00461_2.00 		Mus musculus
NNKABMHNN
NNDKVTMNN		 PBM
Berger et al.(2008)
Six4_2860 		0.708 0.691
Six4
M00563_2.00 		Drosophila melanogaster
NNDANMHNN
NNDKNTHNN		 PBM
Busser et al.(2012a)
Six4 		0.708 0.691
SIX4
M04939_2.00 		Homo sapiens
NVYGATACVB
VBGTATCRBN		 SELEX
Yin et al.(2017)
SIX4_eDBD_HT-SELEX 		0.708 0.691
Six4
M06530_2.00 		Drosophila melanogaster
TGABAC
GTVTCA		 B1H
Mathelier et al.(2014)
MA0204.1 		0.708 0.691
Six4
M06334_2.00 		Drosophila melanogaster
WDDTGABAC
GTVTCAHHW		 B1H
Zhu et al.(2011)
Six4_Cell_FBgn0027364 		0.708 0.691
Six4
M06335_2.00 		Drosophila melanogaster
NTGAKACB
VGTMTCAN		 B1H
Zhu et al.(2011)
Six4_SOLEXA_2_FBgn0027364 		0.708 0.691
Six4
M06336_2.00 		Drosophila melanogaster
NNNTGABA
TVTCANNN		 B1H
Zhu et al.(2011)
Six4_SOLEXA_FBgn0027364 		0.708 0.691
Six4
M09198_2.00 		Mus musculus
DGDAABHNSASNNN
NNNSTSNDVTTHCH		 Misc
Kulakovskiy et al.(2013)
SIX4_MOUSE.H11MO.0.C 		0.708 0.691
SIX4
M10646_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SIX4_Q3 		0.708 0.691
SIX4
M04940_2.00 		Homo sapiens
NBGTAWCRHN
NDYGWTACVN		 SELEX
Yin et al.(2017)
SIX4_eDBD_Methyl-HT-SELEX 		0.708 0.691
SIX5
M08208_2.00 		Homo sapiens
GARWTGTAGT
ACTACAWYTC		 ChIP-seq
Contrino et al.(2012)
Mv121 		0.708 0.655
SIX5
M08209_2.00 		Homo sapiens
GGAGTTGT
ACAACTCC		 ChIP-seq
Contrino et al.(2012)
Mv123 		0.708 0.655
SIX5
M10738_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SIX5_01 		0.708 0.655
SIX5
M10739_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SIX5_02 		0.708 0.655
ceh-34
M00672_2.00 		Caenorhabditis elegans
NNNRDAWNNN
NNNWTHYNNN		 PBM
Narasimhan et al.(2015)
pTH9708 		0.664 0.636
For this family, TFs with SR scores > 0.599 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ML223533a-PA Homeodomain 238 292

Links

Other Homeodomain family TFs
Other Mnemiopsis leidyi TFs

540 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
TEAD3 Homo sapiens ENSG00000007866 D
TEAD1 Homo sapiens ENSG00000187079 D
TEAD4 Homo sapiens ENSG00000197905 D
Tead4 Mus musculus ENSMUSG00000030353 D
Tead1 Mus musculus ENSMUSG00000055320 D
sd Drosophila melanogaster FBgn0003345 D
CpipJ_CPIJ013490 Culex pipiens CpipJ_CPIJ013490 I
AGAP000512 Anopheles gambiae AGAP000512 I
Aqu1.216869 Amphimedon queenslandica Aqu1.216869 I
BGIBMGA001129 Bombyx mori BGIBMGA001129 I
CBG02541 Caenorhabditis briggsae CBG02541 I
CPIJ013490 Culex quinquefasciatus CPIJ013490 I
EFV53558 Trichinella spiralis EFV53558 I
TEAD3 Canis familiaris ENSCAFG00000001326 I
TEAD1 Canis familiaris ENSCAFG00000007976 I
ENSCING00000019408 Ciona intestinalis ENSCING00000019408 I
TEAD1 Callithrix jacchus ENSCJAG00000010263 I
ENSCJAG00000018829 Callithrix jacchus ENSCJAG00000018829 I
ENSCSAVG00000007634 Ciona savignyi ENSCSAVG00000007634 I
tead1a Danio rerio ENSDARG00000028159 I
tead1b Danio rerio ENSDARG00000059483 I
tead3b Danio rerio ENSDARG00000063649 I
TEAD4 Dasypus novemcinctus ENSDNOG00000030589 I
Tead3 Dipodomys ordii ENSDORG00000010798 I
TEAD1 Equus caballus ENSECAG00000008332 I
TEAD3 Equus caballus ENSECAG00000015056 I
ENSFALG00000003635 Ficedula albicollis ENSFALG00000003635 I
TEAD3 Felis catus ENSFCAG00000012905 I
tead3a Gasterosteus aculeatus ENSGACG00000009758 I
tead1b Gasterosteus aculeatus ENSGACG00000015715 I
ENSGALG00000000953 Gallus gallus ENSGALG00000000953 I
TEAD3 Gorilla gorilla ENSGGOG00000001847 I
ENSGMOG00000015271 Gadus morhua ENSGMOG00000015271 I
ENSLACG00000016444 Latimeria chalumnae ENSLACG00000016444 I
TEAD3 Loxodonta africana ENSLAFG00000014818 I
TEAD1 Loxodonta africana ENSLAFG00000016484 I
ENSLOCG00000004054 Lepisosteus oculatus ENSLOCG00000004054 I
ENSLOCG00000009736 Lepisosteus oculatus ENSLOCG00000009736 I
TEAD4 Meleagris gallopavo ENSMGAG00000013910 I
TEAD3 Microcebus murinus ENSMICG00000000029 I
TEAD1 Microcebus murinus ENSMICG00000007178 I
TEAD3 Macaca mulatta ENSMMUG00000015909 I
ENSOARG00000012126 Ovis aries ENSOARG00000012126 I
TEAD3 Otolemur garnettii ENSOGAG00000002943 I
TEAD4 Oryzias latipes ENSORLG00000002553 I
TEAD1 Procavia capensis ENSPCAG00000013657 I
ENSPFOG00000003170 Poecilia formosa ENSPFOG00000003170 I
ENSPFOG00000013997 Poecilia formosa ENSPFOG00000013997 I
ENSPPYG00000003475 Pongo abelii ENSPPYG00000003475 I
ENSPSIG00000006176 Pelodiscus sinensis ENSPSIG00000006176 I
TEAD3 Pan troglodytes ENSPTRG00000018086 I
TEAD3 Pteropus vampyrus ENSPVAG00000002764 I
ENSSHAG00000015930 Sarcophilus harrisii ENSSHAG00000015930 I
TEAD3 Taeniopygia guttata ENSTGUG00000001691 I
tead1a Takifugu rubripes ENSTRUG00000005940 I
tead3a Takifugu rubripes ENSTRUG00000011546 I
TEAD4 Takifugu rubripes ENSTRUG00000016489 I
TEAD3 Tursiops truncatus ENSTTRG00000009434 I
GL22923 Drosophila persimilis FBgn0160513 I
GM22588 Drosophila sechellia FBgn0177458 I
HelroG146479 Helobdella robusta HelroG146479 I
NEMVEDRAFT_v1g86806 Nematostella vectensis NEMVEDRAFT_v1g86806 I
SMAR011013 Strigamia maritima SMAR011013 I
egl-44 Caenorhabditis elegans WBGene00001208 I
Alligator_sinensis_CCG011289.1 Alligator sinensis Alligator_sinensis_CCG011289.1 I
Alligator_sinensis_CCG020461.1 Alligator sinensis Alligator_sinensis_CCG020461.1 I
Cmyd_10009267 Chelonia mydas Cmyd_10009267 I
Ogr18322 Ophisaurus gracilis Ogr18322 I
Pvit_05988 Pogona vitticeps Pvit_05988 I
e_gw.291.69.1 Branchiostoma floridae e_gw.291.69.1 I
HHAL001589-PA Halyomorpha halys HHAL001589-PA I
ACHR008952 Anopheles christyi ACHR008952 I
AEPI008594 Anopheles epiroticus AEPI008594 I
MDOA005382 Musca domestica MDOA005382 I
PPAI001408 Phlebotomus papatasi PPAI001408 I
D917_06432 Trichinella nativa D917_06432 I
D918_02241 Trichuris suis D918_02241 I
ECANG7_01760 Echinococcus canadensis ECANG7_01760 I
NBR_0001654801 Nippostrongylus brasiliensis NBR_0001654801 I
NBR_0002152001 Nippostrongylus brasiliensis NBR_0002152001 I
TsM_000210300 Taenia solium TsM_000210300 I
ENSAPLG00000016417 Anas platyrhynchos ENSAPLG00000016417 N
TEAD1 Bos taurus ENSBTAG00000032657 N
TEAD1 Cavia porcellus ENSCPOG00000001830 N
TEAD1 Echinops telfairi ENSETEG00000009056 N
TEAD1 Gorilla gorilla ENSGGOG00000003412 N
ENSLACG00000016717 Latimeria chalumnae ENSLACG00000016717 N
TEAD1 Macaca mulatta ENSMMUG00000010875 N
ENSNLEG00000017672 Nomascus leucogenys ENSNLEG00000017672 N
TEAD2 Ornithorhynchus anatinus ENSOANG00000013933 N
ENSOANG00000021775 Ornithorhynchus anatinus ENSOANG00000021775 N
TEAD1 Pan troglodytes ENSPTRG00000039896 N
TEAD1 Sorex araneus ENSSARG00000001748 N
TEAD1 Taeniopygia guttata ENSTGUG00000015995 N
TEAD1 Tursiops truncatus ENSTTRG00000006621 N
Aan_R006597 Calypte anna Aan_R006597 N
Afo_R014607 Aptenodytes forsteri Afo_R014607 N
ENSP00000355332 Macaca fascicularis ENSP00000355332 N
Gfo_R013616 Geospiza fortis Gfo_R013616 N
Pvit_10291 Pogona vitticeps Pvit_10291 N
tead1.S Xenopus laevis XB-GENE-5909161 N