IRF1 (Homo sapiens)
IRF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00605 (IRF) IPR001346 ENSG00000125347 T244078_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
IRF1
M08142_2.00		 Homo sapiens
RWANNGAAASYGAAASYRNNN
NNNYRSTTTCRSTTTCNNTWY		 ChIP-seq
Mathelier et al.(2014)
MA0050.2		 (Direct) (Direct)
IRF1
M09233_2.00		 Homo sapiens
NRAANNGAAASWGAAASHRN
NYDSTTTCWSTTTCNNTTYN		 Misc
Kulakovskiy et al.(2013)
IRF1_HUMAN.H11MO.0.A		 (Direct) (Direct)
IRF1
M09594_2.00		 Homo sapiens
GAAASTGAAASY
RSTTTCASTTTC		 Misc
Heinz et al.(2010)
PBMC-IRF1_GSE43036		 (Direct) (Direct)
IRF1
M10879_2.00		 Homo sapiens
SAAAASYGAAASY
RSTTTCRSTTTTS		 Transfac
Matys et al.(2006)
V$IRF1_01		 (Direct) (Direct)
IRF1
M10880_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$IRF1_03		 (Direct) (Direct)
IRF1
M10881_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$IRF1_Q5		 (Direct) (Direct)
IRF1
M10882_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$IRF1_Q6		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Irf1
M09242_2.00 		Mus musculus
VRAANNGAAASYGAAASYVN
NBRSTTTCRSTTTCNNTTYB		 Misc
Kulakovskiy et al.(2013)
IRF1_MOUSE.H11MO.0.A 		1.000 1.000
Irf2
M00805_2.00 		Mus musculus
NDWNHGAAAV
BTTTCDNWHN		 PBM
Weirauch et al.(2013)
pTH2835 		0.771 0.771
IRF2
M05545_2.00 		Homo sapiens
NGAAAVYGAAAS
STTTCRBTTTCN		 SELEX
Yin et al.(2017)
IRF2_FL_HT-SELEX 		0.771 0.771
IRF2
M02691_2.00 		Homo sapiens
SGAAAGYGAAASYNWWHH
DDWWNRSTTTCRCTTTCS		 SELEX
Mathelier et al.(2014)
MA0051.1 		0.771 0.771
IRF2
M09237_2.00 		Homo sapiens
NRAANNGAAASYGAAASYRV
BYRSTTTCRSTTTCNNTTYN		 Misc
Kulakovskiy et al.(2013)
IRF2_HUMAN.H11MO.0.A 		0.771 0.771
Irf2
M09245_2.00 		Mus musculus
NRAANNGAAASYGAAASYRV
BYRSTTTCRSTTTCNNTTYN		 Misc
Kulakovskiy et al.(2013)
IRF2_MOUSE.H11MO.0.B 		0.771 0.771
IRF2
M09596_2.00 		Homo sapiens
NRAAVNRRAASB
VSTTYYNBTTYN		 Misc
Heinz et al.(2010)
Erythroblas-IRF2_GSE36985 		0.771 0.771
IRF2
M10892_2.00 		Homo sapiens
GAAAAGYGAAASY
RSTTTCRCTTTTC		 Transfac
Matys et al.(2006)
V$IRF2_01 		0.771 0.771
IRF2
M10893_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$IRF2_Q6 		0.771 0.771
IRF2
M05546_2.00 		Homo sapiens
NGAAASYGAAAS
STTTCRSTTTCN		 SELEX
Yin et al.(2017)
IRF2_FL_Methyl-HT-SELEX 		0.771 0.771
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000245414 IRF 7 112
ENSP00000384406 IRF 7 112
ENSP00000392455 IRF 7 45
ENSP00000396318 IRF 7 112
ENSP00000405655 IRF 7 112
ENSP00000473661 IRF 7 112
ENSP00000480887 IRF 7 112

Links

Other IRF family TFs
Other Homo sapiens TFs

128 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
CH063_05562 Colletotrichum higginsianum CH063_05562 N
Cob_10031 Colletotrichum orbiculare Cob_10031 N
CSUB01_05024 Colletotrichum sublineola CSUB01_05024 N
GLRG_00161 Colletotrichum graminicola GLRG_00161 N
OIDMADRAFT_207916 Oidiodendron maius OIDMADRAFT_207916 N