MECP2 (Homo sapiens)
MBD

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF01429 (MBD) IPR001739 ENSG00000169057 T260168_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
MECP2
M09257_2.00		 Homo sapiens
SCCGGRR
YYCCGGS		 Misc
Kulakovskiy et al.(2013)
MECP2_HUMAN.H11MO.0.C		 (Direct) (Direct)
MECP2
M11032_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$MECP2_01		 (Direct) (Direct)
MECP2
M11033_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$MECP2_02		 (Direct) (Direct)
MECP2
M11034_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$MECP2_Q4_01		 (Direct) (Direct)
MECP2
M11035_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$MECP2_Q4		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Mecp2
M00806_2.00 		Mus musculus
NNNNNHAHNN
NNDTDNNNNN		 PBM
Weirauch et al.(2013)
pTH3054 		0.973 0.973
Mecp2
M09259_2.00 		Mus musculus
SCCGGRR
YYCCGGS		 Misc
Kulakovskiy et al.(2013)
MECP2_MOUSE.H11MO.0.C 		1.000 1.000
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000301948 MBD 91 162
ENSP00000384865 MBD 103 177
ENSP00000395535 MBD 103 174
ENSP00000479736 MBD 87 160
ENSP00000480973 MBD 91 162
ENSP00000484470 MBD 87 158
ENSP00000486978 MBD 91 165

Links

Other MBD family TFs
Other Homo sapiens TFs

62 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
Mecp2 Mus musculus ENSMUSG00000031393 D 1.000
ENSPMAG00000007809 Petromyzon marinus ENSPMAG00000007809 I 0.714
ENSSHAG00000007851 Sarcophilus harrisii ENSSHAG00000007851 I 1.000
MECP2 Sorex araneus ENSSARG00000012925 I 1.000
Mecp2 Rattus norvegicus ENSRNOG00000056659 I 1.000
MECP2 Pteropus vampyrus ENSPVAG00000000472 I 1.000
MECP2 Pan troglodytes ENSPTRG00000022424 I 1.000
ENSPSIG00000002254 Pelodiscus sinensis ENSPSIG00000002254 I 1.000
ENSPPYG00000020866 Pongo abelii ENSPPYG00000020866 I 0.899
MECP2 Otolemur garnettii ENSOGAG00000015115 I 1.000
ENSPFOG00000002307 Poecilia formosa ENSPFOG00000002307 I 0.889
MECP2 Procavia capensis ENSPCAG00000011826 I 0.931
ENSPANG00000011691 Papio anubis ENSPANG00000011691 I 1.000
mecp2 Oryzias latipes ENSORLG00000020117 I 0.847
ENSONIG00000000809 Oreochromis niloticus ENSONIG00000000809 I 0.875
ENSOARG00000005806 Ovis aries ENSOARG00000005806 I 1.000
ENSSSCG00000012796 Sus scrofa ENSSSCG00000012796 I 1.000
ENSSTOG00000006094 Ictidomys tridecemlineatus ENSSTOG00000006094 I 1.000
mecp2 Tetraodon nigroviridis ENSTNIG00000005114 I 0.875
mecp2 Takifugu rubripes ENSTRUG00000006419 I 0.875
ENSTSYG00000007420 Tarsius syrichta ENSTSYG00000007420 I 1.000
MECP2 Tursiops truncatus ENSTTRG00000004653 I 1.000
ENSXMAG00000003522 Xiphophorus maculatus ENSXMAG00000003522 I 0.889
Cmyd_10000498 Chelonia mydas Cmyd_10000498 I 0.889
ENSP00000395535-D1 Bos grunniens ENSP00000395535-D1 I 1.000
ENSP00000395535 Macaca fascicularis ENSP00000395535 I 1.000
Myotis_brandtii_IRAK1_10010673 Myotis brandtii Myotis_brandtii_IRAK1_10010673 I 1.000
Ogr09995 Ophisaurus gracilis Ogr09995 I 1.000
Pvit_16673 Pogona vitticeps Pvit_16673 I 1.000
mecp2 Xenopus tropicalis XB-GENE-494740 I 0.943
mecp2.S Xenopus laevis XB-GENE-494744 I 0.943
MECP2 Felis catus ENSFCAG00000011389 I 1.000
ENSAMEG00000018448 Ailuropoda melanoleuca ENSAMEG00000018448 I 1.000
ENSAMXG00000017019 Astyanax mexicanus ENSAMXG00000017019 I 0.887
MECP2 Bos taurus ENSBTAG00000047855 I 1.000
MECP2 Canis familiaris ENSCAFG00000019440 I 1.000
MECP2 Callithrix jacchus ENSCJAG00000016796 I 1.000
MECP2 Cavia porcellus ENSCPOG00000012579 I 1.000
ENSCSAG00000006798 Chlorocebus sabaeus ENSCSAG00000006798 I 1.000
mecp2 Danio rerio ENSDARG00000014218 I 0.871
MECP2 Dasypus novemcinctus ENSDNOG00000013419 I 1.000
Mecp2 Dipodomys ordii ENSDORG00000014978 I 1.000
MECP2 Equus caballus ENSECAG00000018208 I 1.000
ENSEEUG00000003070 Erinaceus europaeus ENSEEUG00000003070 I 1.000
ENSEEUG00000015025 Erinaceus europaeus ENSEEUG00000015025 I 1.000
MECP2 Echinops telfairi ENSETEG00000009825 I 1.000
MECP2 Oryctolagus cuniculus ENSOCUG00000013147 I 1.000
mecp2 Gasterosteus aculeatus ENSGACG00000000798 I 0.873
MECP2 Gorilla gorilla ENSGGOG00000000222 I 1.000
ENSLACG00000011281 Latimeria chalumnae ENSLACG00000011281 I 0.974
MECP2 Loxodonta africana ENSLAFG00000016292 I 0.942
ENSLOCG00000014725 Lepisosteus oculatus ENSLOCG00000014725 I 0.901
ENSMEUG00000002761 Macropus eugenii ENSMEUG00000002761 I 1.000
MECP2 Microcebus murinus ENSMICG00000005149 I 1.000
MECP2 Myotis lucifugus ENSMLUG00000014297 I 1.000
MECP2 Macaca mulatta ENSMMUG00000018704 I 1.000
MECP2 Monodelphis domestica ENSMODG00000011643 I 1.000
ENSMPUG00000009072 Mustela putorius furo ENSMPUG00000009072 I 1.000
ENSNLEG00000013783 Nomascus leucogenys ENSNLEG00000013783 I 0.903
MECP2 Ornithorhynchus anatinus ENSOANG00000011024 I 1.000
MECP2 Anolis carolinensis ENSACAG00000012519 I 0.986