| NCBI Gene Info:Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Involved in defense response to Gram-negative bacterium and innate immune response. Predicted to be located in nucleus. Is expressed in several structures, including head; hypodermis; pharynx; reproductive system; and tail. Human ortholog(s) of this gene implicated in Alzheimer's disease; coronary artery disease (multiple); hepatocellular carcinoma; lipid metabolism disorder; and type 2 diabetes mellitus. Orthologous to human PPARA (peroxisome proliferator activated receptor alpha) and PPARD (peroxisome proliferator activated receptor delta). [provided by Alliance of Genome Resources, Apr 2022] |