NFATC4 (Homo sapiens)
Rel

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00554 (RHD_DNA_bind) IPR011539 ENSG00000100968 T317168_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
NFATC4
M01306_2.00		 Homo sapiens
NNNWWWVYRN
NYRBWWWNNN		 PBM
Lambert et al.(2019)
pTH9347		 (Direct) (Direct)
NFATC4
M05701_2.00		 Homo sapiens
DBTTTCCRYN
NRYGGAAAVH		 SELEX
Yin et al.(2017)
NFATC4_eDBD_HT-SELEX_1		 (Direct) (Direct)
NFATC4
M05702_2.00		 Homo sapiens
NKTTCCATGGAAMV
BKTTCCATGGAAMN		 SELEX
Yin et al.(2017)
NFATC4_eDBD_HT-SELEX_2		 (Direct) (Direct)
NFATC4
M05703_2.00		 Homo sapiens
DNTTTCCRYN
NRYGGAAANH		 SELEX
Yin et al.(2017)
NFATC4_eDBD_Methyl-HT-SELEX_1		 (Direct) (Direct)
NFATC4
M05704_2.00		 Homo sapiens
NKTTCCRYGGAAMN
NKTTCCRYGGAAMN		 SELEX
Yin et al.(2017)
NFATC4_eDBD_Methyl-HT-SELEX_2		 (Direct) (Direct)
NFATC4
M09345_2.00		 Homo sapiens
HNDBTTTCCN
NGGAAAVHND		 Misc
Kulakovskiy et al.(2013)
NFAC4_HUMAN.H11MO.0.C		 (Direct) (Direct)
NFATC4
M11219_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NFAT3_Q3_01		 (Direct) (Direct)
NFATC4
M11220_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NFAT3_Q3		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Nfatc4
M09354_2.00 		Mus musculus
HNDBTTTCCN
NGGAAAVHND		 Misc
Kulakovskiy et al.(2013)
NFAC4_MOUSE.H11MO.0.C 		1.000 1.000
Nfatc3
M09359_2.00 		Mus musculus
RDTTTTCCA
TGGAAAAHY		 Misc
Kulakovskiy et al.(2013)
NFAC3_MOUSE.H11MO.0.B 		0.860 0.860
NFATC3
M02440_2.00 		Homo sapiens
DNTTTCCRNN
NNYGGAAANH		 PBM
Weirauch et al.(2014)
pTH9192 		0.856 0.856
NFATC2
M02441_2.00 		Homo sapiens
WNTTTCCRHN
NDYGGAAANW		 PBM
Weirauch et al.(2014)
pTH9196 		0.857 0.857
NFATC3
M05693_2.00 		Homo sapiens
WNTTTCCRYN
NRYGGAAANW		 SELEX
Yin et al.(2017)
NFATC3_eDBD_HT-SELEX_1 		0.856 0.856
NFATC1
M02443_2.00 		Meleagris gallopavo
NNTTTCCRNN
NNYGGAAANN		 PBM
Weirauch et al.(2014)
pTH8315 		0.857 0.857
NFATC3
M05694_2.00 		Homo sapiens
NTTTCCATGGAAAN
NTTTCCATGGAAAN		 SELEX
Yin et al.(2017)
NFATC3_eDBD_HT-SELEX_2 		0.856 0.856
NFATC1
M02444_2.00 		Monodelphis domestica
NNDTTCCDNN
NNHGGAAHNN		 PBM
Weirauch et al.(2014)
pTH8401 		0.857 0.857
NFATC3
M05695_2.00 		Homo sapiens
DYGGAAANNNNNNNTTTCCRH
DYGGAAANNNNNNNTTTCCRH		 SELEX
Yin et al.(2017)
NFATC3_eDBD_HT-SELEX_3 		0.856 0.856
nfatc1
M02446_2.00 		Xenopus tropicalis
NNTTTCCRNN
NNYGGAAANN		 PBM
Weirauch et al.(2014)
pTH8557 		0.857 0.857
NFATC3
M09343_2.00 		Homo sapiens
RDTTTTCCA
TGGAAAAHY		 Misc
Kulakovskiy et al.(2013)
NFAC3_HUMAN.H11MO.0.B 		0.856 0.856
NFATC1
M03449_2.00 		Homo sapiens
HKGRAAADDNWBTTTCCAYN
NRTGGAAAVWNHHTTTYCMD		 SELEX
Jolma et al.(2013)
NFATC1_1 		0.857 0.857
NFATC1
M03450_2.00 		Homo sapiens
TTTCCAYWRYGGAAA
TTTCCRYWRTGGAAA		 SELEX
Jolma et al.(2013)
NFATC1_2 		0.857 0.857
NFATC3
M11217_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NFAT4_Q3 		0.853 0.853
NFATC1
M03451_2.00 		Homo sapiens
NTTTCCATGGAAAN
NTTTCCATGGAAAN		 SELEX
Jolma et al.(2013)
NFATC1_3 		0.857 0.857
NFATC3
M11218_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NFAT4_Q5 		0.853 0.853
NFATC1
M02747_2.00 		Homo sapiens
DTTCCRYGGAA
TTCCRYGGAAH		 SELEX
Jolma et al.(2010)
NFATc1_dimer 		0.857 0.857
NFATC3
M05696_2.00 		Homo sapiens
WNTTTCCRYN
NRYGGAAANW		 SELEX
Yin et al.(2017)
NFATC3_eDBD_Methyl-HT-SELEX_1 		0.853 0.853
NFATC1
M02748_2.00 		Homo sapiens
GGAANDTTCC
GGAAHNTTCC		 SELEX
Jolma et al.(2010)
NFATc1_dimer_type2 		0.857 0.857
NFATC3
M05697_2.00 		Homo sapiens
NTTTCCRYGGAAAN
NTTTCCRYGGAAAN		 SELEX
Yin et al.(2017)
NFATC3_eDBD_Methyl-HT-SELEX_2 		0.853 0.853
NFATC1
M02749_2.00 		Homo sapiens
WDTTTCCAY
RTGGAAAHW		 SELEX
Jolma et al.(2010)
NFATc1_monomer 		0.857 0.857
NFATC3
M05698_2.00 		Homo sapiens
RYGGAAANHNNNDNTTTCCRY
RYGGAAANHNNNDNTTTCCRY		 SELEX
Yin et al.(2017)
NFATC3_eDBD_Methyl-HT-SELEX_3 		0.853 0.853
NFATC1
M05711_2.00 		Homo sapiens
NTTTCCATGGAAAN
NTTTCCATGGAAAN		 SELEX
Yin et al.(2017)
NFATC1_eDBD_HT-SELEX_1 		0.857 0.857
Nfatc2
M09357_2.00 		Mus musculus
NWTTTTCCW
WGGAAAAWN		 Misc
Kulakovskiy et al.(2013)
NFAC2_MOUSE.H11MO.0.C 		0.818 0.818
NFATC1
M05712_2.00 		Homo sapiens
NTTTCCRYNNRYGGAAAN
NTTTCCRYNNRYGGAAAN		 SELEX
Yin et al.(2017)
NFATC1_eDBD_HT-SELEX_2 		0.857 0.857
Nfatc1
M09360_2.00 		Mus musculus
KABTCANWBTTTCCW
WGGAAAVWNTGAVTM		 Misc
Kulakovskiy et al.(2013)
NFAC1_MOUSE.H11MO.0.A 		0.814 0.814
NFATC2
M05705_2.00 		Homo sapiens
DTTTCCATGGAAAM
KTTTCCATGGAAAH		 SELEX
Yin et al.(2017)
NFATC2_eDBD_HT-SELEX_1 		0.857 0.857
NFATC2
M05706_2.00 		Homo sapiens
NTTTCCRYNNRYGGAAAN
NTTTCCRYNNRYGGAAAN		 SELEX
Yin et al.(2017)
NFATC2_eDBD_HT-SELEX_2 		0.857 0.857
NFATC1
M09349_2.00 		Homo sapiens
HBYHWBWBTTTCCWB
VWGGAAAVWVWDRVD		 Misc
Kulakovskiy et al.(2013)
NFAC1_HUMAN.H11MO.0.B 		0.857 0.857
NFATC2
M09346_2.00 		Homo sapiens
NWTTTTCCW
WGGAAAAWN		 Misc
Kulakovskiy et al.(2013)
NFAC2_HUMAN.H11MO.0.B 		0.857 0.857
NFATC1
M09625_2.00 		Homo sapiens
WBTTTCCAYY
RRTGGAAAVW		 Misc
Heinz et al.(2010)
Jurkat-NFATC1_Jolma_et_al. 		0.857 0.857
NFATC2
M11221_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NFAT1_Q4 		0.804 0.804
NFATC2
M11222_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NFAT1_Q5 		0.804 0.804
NFATC2
M11223_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NFAT1_Q6 		0.804 0.804
NFATC2
M08462_2.00 		Homo sapiens
TTTTCCA
TGGAAAA		 COMPILED
Mathelier et al.(2014)
MA0152.1 		0.804 0.804
NFATC1
M11232_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NFAT2_Q4 		0.857 0.857
NFATC2
M05707_2.00 		Homo sapiens
NTTTCCGCGGAAAN
NTTTCCGCGGAAAN		 SELEX
Yin et al.(2017)
NFATC2_eDBD_Methyl-HT-SELEX_1 		0.804 0.804
NFATC1
M11233_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NFAT2_Q5_01 		0.857 0.857
NFATC2
M05708_2.00 		Homo sapiens
NTTTCCRYNNRYGGAAAN
NTTTCCRYNNRYGGAAAN		 SELEX
Yin et al.(2017)
NFATC2_eDBD_Methyl-HT-SELEX_2 		0.804 0.804
NFATC1
M11234_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NFAT2_Q5 		0.857 0.857
NFATC1
M05713_2.00 		Homo sapiens
NTTTCCRYGGAAAN
NTTTCCRYGGAAAN		 SELEX
Yin et al.(2017)
NFATC1_eDBD_Methyl-HT-SELEX_1 		0.857 0.857
NFATC1
M05714_2.00 		Homo sapiens
NTTTCCRYNNRYGGAAAN
NTTTCCRYNNRYGGAAAN		 SELEX
Yin et al.(2017)
NFATC1_eDBD_Methyl-HT-SELEX_2 		0.857 0.857
ENSTNIG00000018271
M02445_2.00 		Tetraodon nigroviridis
DNDTTCCRNN
NNYGGAAHNH		 PBM
Weirauch et al.(2014)
pTH9005 		0.727 0.727
For this family, TFs with SR scores > 0.700 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M01306_2.00 Rel 51 210

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000250373 Rel 419 578
ENSP00000388668 Rel 432 591
ENSP00000388910 Rel 482 641
ENSP00000396788 Rel 407 566
ENSP00000439350 Rel 451 610
ENSP00000450469 Rel 349 508
ENSP00000450590 Rel 419 578
ENSP00000450644 Rel 432 591
ENSP00000450686 Rel 407 566
ENSP00000450733 Rel 349 508
ENSP00000450810 Rel 1 113
ENSP00000451151 Rel 419 578
ENSP00000451183 Rel 1 113
ENSP00000451224 Rel 432 591
ENSP00000451284 Rel 349 508
ENSP00000451395 Rel 1 113
ENSP00000451454 Rel 407 566
ENSP00000451502 Rel 451 610
ENSP00000451992 Rel 111 138
ENSP00000452039 Rel 482 641
ENSP00000452270 Rel 451 610
ENSP00000452349 Rel 349 508

Links

Other Rel family TFs
Other Homo sapiens TFs

258 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
HMPREF1120_08148 Exophiala dermatitidis HMPREF1120_08148 I 0.000
HMPREF1541_00116 Cyphellophora europaea HMPREF1541_00116 I 0.000
OIDMADRAFT_160412 Oidiodendron maius OIDMADRAFT_160412 N 0.000
PV06_07091 Exophiala oligosperma PV06_07091 N 0.000
Z517_12489 Fonsecaea pedrosoi Z517_12489 N 0.000