nfatc1 (Xenopus tropicalis)
Rel

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00554 (RHD_DNA_bind) IPR011539 XB-GENE-876756 T317869_2.00 Misc (2018-Jan-19)

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
nfatc1
M02446_2.00		 Xenopus tropicalis
NNTTTCCRNN
NNYGGAAANN		 PBM
Weirauch et al.(2014)
pTH8557		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Nfatc1
M09360_2.00 		Mus musculus
KABTCANWBTTTCCW
WGGAAAVWNTGAVTM		 Misc
Kulakovskiy et al.(2013)
NFAC1_MOUSE.H11MO.0.A 		0.972 0.972
NFATC1
M02443_2.00 		Meleagris gallopavo
NNTTTCCRNN
NNYGGAAANN		 PBM
Weirauch et al.(2014)
pTH8315 		0.965 0.965
NFATC1
M02444_2.00 		Monodelphis domestica
NNDTTCCDNN
NNHGGAAHNN		 PBM
Weirauch et al.(2014)
pTH8401 		0.944 0.944
NFATC1
M03449_2.00 		Homo sapiens
HKGRAAADDNWBTTTCCAYN
NRTGGAAAVWNHHTTTYCMD		 SELEX
Jolma et al.(2013)
NFATC1_1 		0.895 0.895
NFATC1
M03450_2.00 		Homo sapiens
TTTCCAYWRYGGAAA
TTTCCRYWRTGGAAA		 SELEX
Jolma et al.(2013)
NFATC1_2 		0.895 0.895
NFATC1
M03451_2.00 		Homo sapiens
NTTTCCATGGAAAN
NTTTCCATGGAAAN		 SELEX
Jolma et al.(2013)
NFATC1_3 		0.895 0.895
NFATC1
M02747_2.00 		Homo sapiens
DTTCCRYGGAA
TTCCRYGGAAH		 SELEX
Jolma et al.(2010)
NFATc1_dimer 		0.895 0.895
NFATC1
M02748_2.00 		Homo sapiens
GGAANDTTCC
GGAAHNTTCC		 SELEX
Jolma et al.(2010)
NFATc1_dimer_type2 		0.895 0.895
NFATC1
M02749_2.00 		Homo sapiens
WDTTTCCAY
RTGGAAAHW		 SELEX
Jolma et al.(2010)
NFATc1_monomer 		0.895 0.895
NFATC1
M05711_2.00 		Homo sapiens
NTTTCCATGGAAAN
NTTTCCATGGAAAN		 SELEX
Yin et al.(2017)
NFATC1_eDBD_HT-SELEX_1 		0.895 0.895
NFATC1
M05712_2.00 		Homo sapiens
NTTTCCRYNNRYGGAAAN
NTTTCCRYNNRYGGAAAN		 SELEX
Yin et al.(2017)
NFATC1_eDBD_HT-SELEX_2 		0.895 0.895
NFATC1
M09349_2.00 		Homo sapiens
HBYHWBWBTTTCCWB
VWGGAAAVWVWDRVD		 Misc
Kulakovskiy et al.(2013)
NFAC1_HUMAN.H11MO.0.B 		0.895 0.895
NFATC1
M09625_2.00 		Homo sapiens
WBTTTCCAYY
RRTGGAAAVW		 Misc
Heinz et al.(2010)
Jurkat-NFATC1_Jolma_et_al. 		0.895 0.895
NFATC1
M11232_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NFAT2_Q4 		0.895 0.895
NFATC1
M11233_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NFAT2_Q5_01 		0.895 0.895
NFATC1
M11234_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NFAT2_Q5 		0.895 0.895
NFATC1
M05713_2.00 		Homo sapiens
NTTTCCRYGGAAAN
NTTTCCRYGGAAAN		 SELEX
Yin et al.(2017)
NFATC1_eDBD_Methyl-HT-SELEX_1 		0.895 0.895
NFATC1
M05714_2.00 		Homo sapiens
NTTTCCRYNNRYGGAAAN
NTTTCCRYNNRYGGAAAN		 SELEX
Yin et al.(2017)
NFATC1_eDBD_Methyl-HT-SELEX_2 		0.895 0.895
NFATC2
M02441_2.00 		Homo sapiens
WNTTTCCRHN
NDYGGAAANW		 PBM
Weirauch et al.(2014)
pTH9196 		0.853 0.853
NFATC2
M05705_2.00 		Homo sapiens
DTTTCCATGGAAAM
KTTTCCATGGAAAH		 SELEX
Yin et al.(2017)
NFATC2_eDBD_HT-SELEX_1 		0.853 0.853
NFATC2
M05706_2.00 		Homo sapiens
NTTTCCRYNNRYGGAAAN
NTTTCCRYNNRYGGAAAN		 SELEX
Yin et al.(2017)
NFATC2_eDBD_HT-SELEX_2 		0.853 0.853
NFATC2
M09346_2.00 		Homo sapiens
NWTTTTCCW
WGGAAAAWN		 Misc
Kulakovskiy et al.(2013)
NFAC2_HUMAN.H11MO.0.B 		0.853 0.853
NFATC2
M11221_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NFAT1_Q4 		0.853 0.853
NFATC2
M11222_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NFAT1_Q5 		0.853 0.853
NFATC2
M11223_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NFAT1_Q6 		0.853 0.853
NFATC2
M08462_2.00 		Homo sapiens
TTTTCCA
TGGAAAA		 COMPILED
Mathelier et al.(2014)
MA0152.1 		0.853 0.853
NFATC2
M05707_2.00 		Homo sapiens
NTTTCCGCGGAAAN
NTTTCCGCGGAAAN		 SELEX
Yin et al.(2017)
NFATC2_eDBD_Methyl-HT-SELEX_1 		0.853 0.853
NFATC2
M05708_2.00 		Homo sapiens
NTTTCCRYNNRYGGAAAN
NTTTCCRYNNRYGGAAAN		 SELEX
Yin et al.(2017)
NFATC2_eDBD_Methyl-HT-SELEX_2 		0.853 0.853
NFATC3
M02440_2.00 		Homo sapiens
DNTTTCCRNN
NNYGGAAANH		 PBM
Weirauch et al.(2014)
pTH9192 		0.846 0.846
NFATC3
M05693_2.00 		Homo sapiens
WNTTTCCRYN
NRYGGAAANW		 SELEX
Yin et al.(2017)
NFATC3_eDBD_HT-SELEX_1 		0.846 0.846
NFATC3
M05694_2.00 		Homo sapiens
NTTTCCATGGAAAN
NTTTCCATGGAAAN		 SELEX
Yin et al.(2017)
NFATC3_eDBD_HT-SELEX_2 		0.846 0.846
NFATC3
M05695_2.00 		Homo sapiens
DYGGAAANNNNNNNTTTCCRH
DYGGAAANNNNNNNTTTCCRH		 SELEX
Yin et al.(2017)
NFATC3_eDBD_HT-SELEX_3 		0.846 0.846
NFATC3
M09343_2.00 		Homo sapiens
RDTTTTCCA
TGGAAAAHY		 Misc
Kulakovskiy et al.(2013)
NFAC3_HUMAN.H11MO.0.B 		0.846 0.846
Nfatc2
M09357_2.00 		Mus musculus
NWTTTTCCW
WGGAAAAWN		 Misc
Kulakovskiy et al.(2013)
NFAC2_MOUSE.H11MO.0.C 		0.846 0.846
Nfatc3
M09359_2.00 		Mus musculus
RDTTTTCCA
TGGAAAAHY		 Misc
Kulakovskiy et al.(2013)
NFAC3_MOUSE.H11MO.0.B 		0.846 0.846
NFATC3
M11217_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NFAT4_Q3 		0.846 0.846
NFATC3
M11218_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NFAT4_Q5 		0.846 0.846
NFATC3
M05696_2.00 		Homo sapiens
WNTTTCCRYN
NRYGGAAANW		 SELEX
Yin et al.(2017)
NFATC3_eDBD_Methyl-HT-SELEX_1 		0.846 0.846
NFATC3
M05697_2.00 		Homo sapiens
NTTTCCRYGGAAAN
NTTTCCRYGGAAAN		 SELEX
Yin et al.(2017)
NFATC3_eDBD_Methyl-HT-SELEX_2 		0.846 0.846
NFATC3
M05698_2.00 		Homo sapiens
RYGGAAANHNNNDNTTTCCRY
RYGGAAANHNNNDNTTTCCRY		 SELEX
Yin et al.(2017)
NFATC3_eDBD_Methyl-HT-SELEX_3 		0.846 0.846
NFATC4
M01306_2.00 		Homo sapiens
NNNWWWVYRN
NYRBWWWNNN		 PBM
Lambert et al.(2019)
pTH9347 		0.797 0.797
NFATC4
M05701_2.00 		Homo sapiens
DBTTTCCRYN
NRYGGAAAVH		 SELEX
Yin et al.(2017)
NFATC4_eDBD_HT-SELEX_1 		0.797 0.797
NFATC4
M05702_2.00 		Homo sapiens
NKTTCCATGGAAMV
BKTTCCATGGAAMN		 SELEX
Yin et al.(2017)
NFATC4_eDBD_HT-SELEX_2 		0.797 0.797
NFATC4
M09345_2.00 		Homo sapiens
HNDBTTTCCN
NGGAAAVHND		 Misc
Kulakovskiy et al.(2013)
NFAC4_HUMAN.H11MO.0.C 		0.797 0.797
Nfatc4
M09354_2.00 		Mus musculus
HNDBTTTCCN
NGGAAAVHND		 Misc
Kulakovskiy et al.(2013)
NFAC4_MOUSE.H11MO.0.C 		0.797 0.797
NFATC4
M11219_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NFAT3_Q3_01 		0.797 0.797
NFATC4
M11220_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NFAT3_Q3 		0.797 0.797
NFATC4
M05703_2.00 		Homo sapiens
DNTTTCCRYN
NRYGGAAANH		 SELEX
Yin et al.(2017)
NFATC4_eDBD_Methyl-HT-SELEX_1 		0.797 0.797
NFATC4
M05704_2.00 		Homo sapiens
NKTTCCRYGGAAMN
NKTTCCRYGGAAMN		 SELEX
Yin et al.(2017)
NFATC4_eDBD_Methyl-HT-SELEX_2 		0.797 0.797
ENSTNIG00000018271
M02445_2.00 		Tetraodon nigroviridis
DNDTTCCRNN
NNYGGAAHNH		 PBM
Weirauch et al.(2014)
pTH9005 		0.762 0.762
For this family, TFs with SR scores > 0.700 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M02446_2.00 Rel 51 211

DNA Binding Domains

Protein ID Domain From To Sequence
AAI25727 Rel 417 577

Links

Other Rel family TFs
Other Xenopus tropicalis TFs

252 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
FGRRES_17238 Fusarium graminearum FGRRES_17238 D 0.000
PV11_06331 Exophiala sideris PV11_06331 I 0.000
VDBG_00856 Verticillium albo atrum VDBG_00856 I 0.000
MYCTH_122893 Myceliophthora thermophila MYCTH_122893 I 0.000
OIDMADRAFT_141009 Oidiodendron maius OIDMADRAFT_141009 I 0.000
PV04_08189 Capronia semiimmersa PV04_08189 I 0.000
PV05_09089 Exophiala xenobiotica PV05_09089 I 0.000
PV06_02589 Exophiala oligosperma PV06_02589 I 0.000
PV07_11936 Cladophialophora immunda PV07_11936 I 0.000
PV08_11364 Exophiala spinifera PV08_11364 I 0.000
HMPREF1624_05953 Sporothrix schenckii HMPREF1624_05953 I 0.000
SPBR_00057 Sporothrix brasiliensis SPBR_00057 I 0.000
SS1G_03098 Sclerotinia sclerotiorum SS1G_03098 I 0.000
UV8b_5932 Ustilaginoidea virens UV8b_5932 I 0.000
VDAG_00465 Verticillium dahliae VDAG_00465 I 0.000
VDBG_00856 Verticillium alfalfae VDBG_00856 I 0.000
VHEMI03354 Torrubiella hemipterigena VHEMI03354 I 0.000
Z517_03357 Fonsecaea pedrosoi Z517_03357 I 0.000
Z518_06732 Rhinocladiella mackenziei Z518_06732 I 0.000
Z519_05358 Cladophialophora bantiana Z519_05358 I 0.000
CSUB01_02000 Colletotrichum sublineola CSUB01_02000 I 0.000
A1O1_04664 Capronia coronata A1O1_04664 I 0.000
A1O5_09249 Cladophialophora psammophila A1O5_09249 I 0.000
A1O7_07701 Cladophialophora yegresii A1O7_07701 I 0.000
A1O9_01966 Exophiala aquamarina A1O9_01966 I 0.000
ACRE_004430 Acremonium chrysogenum ACRE_004430 I 0.000
Bcin06g06480 Botrytis cinerea Bcin06g06480 I 0.000
CGGC5_14308 Colletotrichum gloeosporioides CGGC5_14308 I 0.000
CH063_05452 Colletotrichum higginsianum CH063_05452 I 0.000
CMQ_3175 Grosmannia clavigera CMQ_3175 I 0.000
HMPREF1120_01670 Exophiala dermatitidis HMPREF1120_01670 I 0.000
EPUS_00089 Endocarpon pusillum EPUS_00089 I 0.000
F503_02949 Ophiostoma piceae uamh F503_02949 I 0.000
FFUJ_04435 Fusarium fujikuroi FFUJ_04435 I 0.000
FOXG_05651 Fusarium oxysporum FOXG_05651 I 0.000
FVEG_04119 Fusarium verticillioides FVEG_04119 I 0.000
G647_02381 Cladophialophora carrionii G647_02381 I 0.000
GLRG_08361 Colletotrichum graminicola GLRG_08361 I 0.000
PITC_097210 Penicillium italicum PITC_097210 N 0.000
PEX1_081420 Penicillium expansum PEX1_081420 N 0.000
PAAG_02161 Paracoccidioides sp lutzii PAAG_02161 N 0.000
A1O3_06687 Capronia epimyces A1O3_06687 N 0.000