RUNX1 (Homo sapiens)
Runt

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00853 (Runt) IPR013524 ENSG00000159216 T319384_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
RUNX1
M09371_2.00		 Homo sapiens
NWAACCACARV
BYTGTGGTTWN		 Misc
Kulakovskiy et al.(2013)
RUNX1_HUMAN.H11MO.0.A		 (Direct) (Direct)
RUNX1
M09631_2.00		 Homo sapiens
VCCACWTCCTBY
RVAGGAWGTGGB		 Misc
Heinz et al.(2010)
Jurkat-RUNX1_GSE17954		 (Direct) (Direct)
RUNX1
M09632_2.00		 Homo sapiens
HAACCACADV
BHTGTGGTTD		 Misc
Heinz et al.(2010)
Jurkat-RUNX1_GSE29180		 (Direct) (Direct)
RUNX1
M11258_2.00		 Homo sapiens
ACCRCA
TGYGGT		 Transfac
Matys et al.(2006)
V$AML1_01		 (Direct) (Direct)
RUNX1
M11259_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$AML1_Q4_01		 (Direct) (Direct)
RUNX1
M11260_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$AML1_Q4_02		 (Direct) (Direct)
RUNX1
M11261_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$AML1_Q4		 (Direct) (Direct)
RUNX1
M11262_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$AML1_Q5		 (Direct) (Direct)
RUNX1
M11263_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$AML1_Q6		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Runx1
M08163_2.00 		Mus musculus
HRRCCACARVN
NBYTGTGGYYD		 ChIP-seq
Mathelier et al.(2014)
MA0002.2 		1.000 1.000
Runx1
M09372_2.00 		Mus musculus
VWRACCACARVV
BBYTGTGGTYWB		 Misc
Kulakovskiy et al.(2013)
RUNX1_MOUSE.H11MO.0.A 		1.000 1.000
Runx1
M09633_2.00 		Mus musculus
NWAACCACAR
YTGTGGTTWN		 Misc
Heinz et al.(2010)
HPC7-Runx1_GSE22178 		0.985 0.985
RUNX3
M03464_2.00 		Homo sapiens
HRACCGCAAACCRCAN
NTGYGGTTTGCGGTYD		 SELEX
Jolma et al.(2013)
RUNX3_1 		0.915 0.915
RUNX3
M03465_2.00 		Homo sapiens
WAACCRCARN
NYTGYGGTTW		 SELEX
Jolma et al.(2013)
RUNX3_2 		0.931 0.931
RUNX3
M03466_2.00 		Homo sapiens
HDACCRCADWAACCRCRN
NYGYGGTTWHTGYGGTHD		 SELEX
Jolma et al.(2013)
RUNX3_3 		0.931 0.931
RUNX3
M03467_2.00 		Homo sapiens
HRACCRCAAH
DTTGYGGTYD		 SELEX
Jolma et al.(2013)
RUNX3_4 		0.931 0.931
RUNX3
M02751_2.00 		Homo sapiens
WACCRCAM
KTGYGGTW		 SELEX
Jolma et al.(2010)
RUNX3_monomer 		0.915 0.915
RUNX3
M05731_2.00 		Homo sapiens
YWAACCGCAAAAACCGCARV
BYTGCGGTTTTTGCGGTTWR		 SELEX
Yin et al.(2017)
RUNX3_FL_HT-SELEX 		0.915 0.915
RUNX3
M09369_2.00 		Homo sapiens
HAACCACARN
NYTGTGGTTD		 Misc
Kulakovskiy et al.(2013)
RUNX3_HUMAN.H11MO.0.A 		0.931 0.931
Runx3
M09374_2.00 		Mus musculus
NHRACCACARVN
NBYTGTGGTYDN		 Misc
Kulakovskiy et al.(2013)
RUNX3_MOUSE.H11MO.0.A 		0.931 0.931
RUNX3
M11252_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$AML2_Q3_01 		0.931 0.931
RUNX3
M11253_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$AML2_Q3 		0.915 0.915
RUNX3
M11254_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$AML2_Q4 		0.931 0.931
RUNX3
M05732_2.00 		Homo sapiens
HWAACCACRAAAACCACRARN
NYTYGTGGTTTTYGTGGTTWD		 SELEX
Yin et al.(2017)
RUNX3_FL_Methyl-HT-SELEX 		0.931 0.931
Runx2
M01307_2.00 		Mus musculus
NHDACCRCAN
NTGYGGTHDN		 PBM
Lambert et al.(2019)
pTH9764 		0.923 0.923
RUNX2
M03468_2.00 		Homo sapiens
HRACCGCAAACCRCRD
HYGYGGTTTGCGGTYD		 SELEX
Jolma et al.(2013)
RUNX2_1 		0.923 0.923
RUNX2
M03469_2.00 		Homo sapiens
HRACCRCADWWACCRCAD
HTGYGGTWWHTGYGGTYD		 SELEX
Jolma et al.(2013)
RUNX2_2 		0.908 0.908
RUNX2
M03470_2.00 		Homo sapiens
WAACCRCAR
YTGYGGTTW		 SELEX
Jolma et al.(2013)
RUNX2_3 		0.923 0.923
RUNX2
M05733_2.00 		Homo sapiens
NHRACCRCADWAACCRCAVN
NBTGYGGTTWHTGYGGTYDN		 SELEX
Yin et al.(2017)
RUNX2_eDBD_HT-SELEX 		0.908 0.908
RUNX2
M09370_2.00 		Homo sapiens
MMHAACCACAVVMH
DKBBTGTGGTTDKK		 Misc
Kulakovskiy et al.(2013)
RUNX2_HUMAN.H11MO.0.A 		0.923 0.923
Runx2
M09373_2.00 		Mus musculus
VWRACCACARVV
BBYTGTGGTYWB		 Misc
Kulakovskiy et al.(2013)
RUNX2_MOUSE.H11MO.0.A 		0.882 0.882
RUNX2
M09630_2.00 		Homo sapiens
NHVACCACANNN
NNNTGTGGTBDN		 Misc
Heinz et al.(2010)
PCa-RUNX2_GSE33889 		0.923 0.923
RUNX2
M11255_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$AML3_Q3 		0.923 0.923
RUNX2
M11256_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$AML3_Q6 		0.923 0.923
RUNX2
M11257_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$OSF2_Q6 		0.908 0.908
RUNX2
M05734_2.00 		Homo sapiens
NWAACCACRAAAACCACRRN
NYYGTGGTTTTYGTGGTTWN		 SELEX
Yin et al.(2017)
RUNX2_eDBD_Methyl-HT-SELEX 		0.882 0.882
lz
M03964_2.00 		Drosophila melanogaster
HRACCGCAAHM
KDTTGCGGTYD		 SELEX
Nitta et al.(2015)
lz_1 		0.731 0.731
lz
M03965_2.00 		Drosophila melanogaster
HVACCRCARWAACCRCAV
BTGYGGTTWYTGYGGTBD		 SELEX
Nitta et al.(2015)
lz_2 		0.731 0.731
lz
M03966_2.00 		Drosophila melanogaster
WRACCRCAWTAACCRCAA
TTGYGGTTAWTGYGGTYW		 SELEX
Nitta et al.(2015)
lz_3 		0.731 0.731
lz
M03967_2.00 		Drosophila melanogaster
HRACCGCAAAACCRCAR
YTGYGGTTTTGCGGTYD		 SELEX
Nitta et al.(2015)
lz_4 		0.731 0.731
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000300305 Runt 78 207
ENSP00000340690 Runt 51 180
ENSP00000351123 Runt 51 180
ENSP00000382182 Runt 66 195
ENSP00000382184 Runt 51 180
ENSP00000388189 Runt 65 140
ENSP00000409227 Runt 78 207

Links

Other Runt family TFs
Other Homo sapiens TFs

356 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
SPBR_01267 Sporothrix brasiliensis SPBR_01267 N 0.000
MANI_026245 Metarhizium anisopliae MANI_026245 N 0.000
MBR_07611 Metarhizium brunneum MBR_07611 N 0.000
MGU_03902 Metarhizium guizhouense MGU_03902 N 0.000
NechaG71135 Fusarium solani NechaG71135 N 0.000
PFICI_08003 Pestalotiopsis fici PFICI_08003 N 0.000
PODANS_7_2610 Podospora anserina PODANS_7_2610 N 0.000
S40285_00214 Stachybotrys chlorohalonata S40285_00214 N 0.000
S40288_02231 Stachybotrys chartarum S40288_02231 N 0.000
MAJ_03545 Metarhizium majus MAJ_03545 N 0.000
THITE_2155541 Thielavia terrestris THITE_2155541 N 0.000
TRIATDRAFT_52152 Trichoderma atroviride TRIATDRAFT_52152 N 0.000
UV8b_1336 Ustilaginoidea virens UV8b_1336 N 0.000
VDBG_06797 Verticillium alfalfae VDBG_06797 N 0.000
VHEMI09995 Torrubiella hemipterigena VHEMI09995 N 0.000
X797_003277 Metarhizium robertsii X797_003277 N 0.000
estExt_Genewise1Plus.C_sca_10_chr8_2_00572 Nectria haematococca estExt_Genewise1Plus.C_sca_10_chr8_2_00572 N 0.000
estExt_fgenesh1_pg.C_10747 Cryphonectria parasitica estExt_fgenesh1_pg.C_10747 N 0.000
FFUJ_08604 Fusarium fujikuroi FFUJ_08604 N 0.000
ACRE_075020 Acremonium chrysogenum ACRE_075020 N 0.000
CCM_07503 Cordyceps militaris CCM_07503 N 0.000
CFIO01_13578 Colletotrichum fioriniae CFIO01_13578 N 0.000
CGGC5_547 Colletotrichum gloeosporioides CGGC5_547 N 0.000
Cob_10044 Colletotrichum orbiculare Cob_10044 N 0.000
CPUR_04956 Claviceps purpurea CPUR_04956 N 0.000
CSUB01_05031 Colletotrichum sublineola CSUB01_05031 N 0.000
F503_04396 Ophiostoma piceae uamh F503_04396 N 0.000
VDBG_06797 Verticillium albo atrum VDBG_06797 N 0.000
FGRRES_12742 Fusarium graminearum FGRRES_12742 N 0.000
FOXG_09425 Fusarium oxysporum FOXG_09425 N 0.000
FPSE_03532 Fusarium pseudograminearum FPSE_03532 N 0.000
FVEG_07057 Fusarium verticillioides FVEG_07057 N 0.000
GGTG_09471 Gaeumannomyces graminis GGTG_09471 N 0.000
GLRG_00168 Colletotrichum graminicola GLRG_00168 N 0.000
HMPREF1624_03120 Sporothrix schenckii HMPREF1624_03120 N 0.000